Gene: Edn1 (endothelin 1) Rattus norvegicus
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Symbol: Edn1
Name: endothelin 1
Description: ENCODES a protein that exhibits endothelin A receptor binding; endothelin B receptor binding; cytokine activity (ortholog); INVOLVED IN artery smooth muscle contraction; cell growth; cellular response to calcium ion; PARTICIPATES IN inflammatory response pathway; endothelin signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH Albuminuria; Brain Ischemia; Bronchopulmonary Dysplasia; FOUND IN basal part of cell; extracellular space; rough endoplasmic reticulum lumen; INTERACTS WITH (+)-catechin; (R)-noradrenaline; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endothelin-1; ET-1; Et1; PPET1; preproendothelin-1
Orthologs:
Homo sapiens : EDN1 (endothelin 1)  HGNC
Mus musculus : Edn1 (endothelin 1)  MGI
more info ...
Is Marker For: Strains:   SD   F344.OLETF-(D17Mgh4-Edn1)/Tj  
QTLs:   Niddm32  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01722,136,814 - 22,143,745 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01724,117,499 - 24,124,188 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41728,303,886 - 28,309,775 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11728,306,726 - 28,312,616 (-)NCBI
Celera1722,134,975 - 22,140,901 (-)NCBI
Cytogenetic Map17p13NCBImapview
Model


Disease Annotations
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Gene Ontology Annotations
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References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Edn1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2532
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE