Gene: Edn1 (endothelin 1) Rattus norvegicus
Symbol: Edn1
Name: endothelin 1
Description: ENCODES a protein that exhibits endothelin A receptor binding; endothelin B receptor binding; cytokine activity (ortholog); INVOLVED IN artery smooth muscle contraction; cellular response to calcium ion; cellular response to drug; PARTICIPATES IN inflammatory response pathway; endothelin signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH adult respiratory distress syndrome; Albuminuria; aspiration pneumonitis; FOUND IN basal part of cell; extracellular space; rough endoplasmic reticulum lumen; INTERACTS WITH (+)-catechin; (R)-noradrenaline; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endothelin-1; ET-1; Et1; PPET1; preproendothelin-1
Homo sapiens (human) : EDN1 (endothelin 1)  HGNC  AGR
Mus musculus (house mouse) : Edn1 (endothelin 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Edn1 (endothelin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EDN1 (endothelin 1)
Canis lupus familiaris (dog) : EDN1 (endothelin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Edn1 (endothelin 1)
more info ...
Is Marker For: Strains:   SD   F344.OLETF-(D17Mgh4-Edn1)/Tj  
QTLs:   Niddm32  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01722,136,814 - 22,143,745 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01724,117,499 - 24,124,188 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41728,303,886 - 28,309,775 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11728,306,726 - 28,312,616 (-)NCBI
Celera1722,134,975 - 22,140,901 (-)NCBI
Cytogenetic Map17p13NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants