Gene: Wrn (Werner syndrome RecQ like helicase) Rattus norvegicus
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Symbol: Wrn
Name: Werner syndrome RecQ like helicase
Description: ENCODES a protein that exhibits chromatin binding; 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); INVOLVED IN brain development; base-excision repair (ortholog); cell aging (ortholog); ASSOCIATED WITH Aging, Premature (ortholog); Breast Neoplasms (ortholog); Cardiomyopathy, Restrictive (ortholog); FOUND IN neuron projection; centrosome (ortholog); chromosome, telomeric region (ortholog); INTERACTS WITH cisplatin; ketamine; sodium arsenite
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290805; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome, RecQ helicase-like
Orthologs:
Homo sapiens (human) : WRN (Werner syndrome RecQ like helicase)  HGNC  AGR
Mus musculus (house mouse) : Wrn (Werner syndrome RecQ like helicase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Wrn (Werner syndrome RecQ like helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : WRN (Werner syndrome RecQ like helicase)
Canis lupus familiaris (dog) : WRN (Werner syndrome RecQ like helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wrn (Werner syndrome RecQ like helicase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01662,483,773 - 62,619,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01662,148,560 - 62,283,748 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41662,535,144 - 62,668,700 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1656,796,927 - 56,929,877 (+)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Wrn
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564788
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-12-05
Status: ACTIVE