Gene: Wrn (Werner syndrome RecQ like helicase) Rattus norvegicus
Symbol: Wrn
Name: Werner syndrome RecQ like helicase
Description: ENCODES a protein that exhibits chromatin binding; 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); INVOLVED IN brain development; base-excision repair (ortholog); cell aging (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiomyopathy, Restrictive (ortholog); Coronary Artery Disease (ortholog); FOUND IN neuron projection; centrosome (ortholog); MutLalpha complex (ortholog); INTERACTS WITH cisplatin; ketamine; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290805; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome, RecQ helicase-like
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01662,483,751 - 62,618,936 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01662,148,560 - 62,283,748 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41662,535,144 - 62,668,700 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1656,796,905 - 56,929,877 (+)NCBI
Cytogenetic Map16q12.3NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Wrn
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1564788
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE