Gene: Wrn (Werner syndrome, RecQ helicase-like) Rattus norvegicus
Symbol: Wrn
Name: Werner syndrome, RecQ helicase-like
Description: ENCODES a protein that exhibits chromatin binding; 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); INVOLVED IN brain development; base-excision repair (ortholog); cell aging (ortholog); ASSOCIATED WITH Breast Cancer, Familial (ortholog); Breast Neoplasms (ortholog); Cardiomyopathy, Restrictive (ortholog); FOUND IN neuron projection; centrosome (ortholog); MutLalpha complex (ortholog); INTERACTS WITH cisplatin; ketamine; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290805; RGD1564788; similar to Werner syndrome helicase homolog
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01662,483,751 - 62,618,936+NCBI
Rat Cytogenetic Map16q12.3 NCBI
RGSC Genome Assembly v5.01662,148,560 - 62,283,748+NCBI
RGSC Genome Assembly v3.41662,535,144 - 62,668,700+NCBI
Rat Celera Assembly1656,796,905 - 56,929,877+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Wrn
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1564788
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2015-11-09
Status: ACTIVE