Gene: Srd5a1 (steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1))  Rattus norvegicus

Symbol: Srd5a1
Name: steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Description: ENCODES a protein that exhibits 3-oxo-5-alpha-steroid 4-dehydrogenase activity; amide binding; NADPH binding; INVOLVED IN androgen biosynthetic process; androgen metabolic process; bone development; PARTICIPATES IN testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2; Hyperprolactinemia; Hypothyroidism; FOUND IN cell body fiber; cytoplasm; intracellular membrane-bounded organelle; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one; 2,2',4,4',5,5'-hexachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-oxo-5-alpha-steroid 4-dehydrogenase 1; MGC156498; S5AR 1; SR type 1; steroid 5 alpha-reductase 1; steroid 5-alpha-reductase 1; steroid-5-alpha-reductase 1; Steroid-5-alpha-reductase alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Orthologs: Homo sapiens : SRD5A1 (steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1))  HGNC
Mus musculus : Srd5a1 (steroid 5 alpha-reductase 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map17p14 NCBI
RGSC Genome Assembly v5.0137,717,526 - 37,751,716+NCBI
RGSC Genome Assembly v3.4173,845,190 - 3,879,165+NCBI
Rat Celera Assembly132,290,558 - 32,325,770+NCBI
Genome Assembly 3.1173,845,345 - 3,877,557+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Srd5a1
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RGD Object Information
RGD ID: 3757
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE