| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SRD5A1 mRNA | CTD | PMID:16940010 |
| 17beta-hydroxy-5alpha-androstan-3-one | affects expression | EXP | | 6480464 | Dihydrotestosterone affects the expression of SRD5A1 mRNA | CTD | PMID:22131296 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A1 protein | CTD | PMID:19464308 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SRD5A1 mRNA | CTD | PMID:16984957 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:11341 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:18796159 PMID:16984957 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:11341 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SRD5A1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:11341 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:16984957 PMID:18796159 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:18178546 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:11341 | 6480464 | AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA] | CTD | PMID:16984957 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRD5A1 mRNA | CTD | PMID:18178546 more ... |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of SRD5A1 mRNA | CTD | PMID:21346803 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of SRD5A1 mRNA | CTD | PMID:21346803 |
| 2-methylcholine | affects expression | ISO | RGD:736446 | 6480464 | beta-methylcholine affects the expression of SRD5A1 mRNA | CTD | PMID:21179406 |
| 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A1 protein | CTD | PMID:19464308 |
| 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRD5A1 mRNA | CTD | PMID:20959002 |
| 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SRD5A1 mRNA | CTD | PMID:16984957 |
| 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of SRD5A1 mRNA | CTD | PMID:19162173 |
| 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:11341 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of SRD5A1 mRNA | CTD | PMID:18648102 |
| acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SRD5A1 mRNA | CTD | PMID:22459607 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SRD5A1 mRNA | CTD | PMID:16483693 |
| Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of SRD5A1 mRNA | CTD | PMID:18178546 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:11341 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of SRD5A1 mRNA; more ... | CTD | PMID:21715664 |
| bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of SRD5A1 mRNA | CTD | PMID:19560483 |
| bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SRD5A1 mRNA; more ... | CTD | PMID:23405234 |
| choline | multiple interactions | ISO | RGD:11341 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SRD5A1 gene | CTD | PMID:20938992 |
| ciguatoxin CTX1B | affects expression | ISO | RGD:11341 | 6480464 | Ciguatoxins affects the expression of SRD5A1 mRNA | CTD | PMID:18353800 |
| clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SRD5A1 mRNA | CTD | PMID:17602206 |
| copper(2+) sulfate | decreases expression | ISO | RGD:736446 | 6480464 | Copper Sulfate results in decreased expression of SRD5A1 mRNA | CTD | PMID:19549813 |
| cumene | multiple interactions | ISO | RGD:11341 | 6480464 | [cumene co-treated with KRAS gene mutant form] results in decreased expression of SRD5A1 mRNA | CTD | PMID:18648096 |
| dehydroepiandrosterone | affects metabolic processing | EXP | | 6480464 | SRD5A1 protein affects the metabolism of Dehydroepiandrosterone | CTD | PMID:15261307 |
| diarsenic trioxide | decreases expression | ISO | RGD:736446 | 6480464 | arsenic trioxide results in decreased expression of SRD5A1 mRNA | CTD | PMID:19769630 |
| dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SRD5A1 mRNA | CTD | PMID:19560483 |
| dioxygen | increases expression | ISO | RGD:11341 | 6480464 | Oxygen deficiency results in increased expression of SRD5A1 mRNA | CTD | PMID:20880076 |
| dipentyl phthalate | decreases expression | EXP | | 6480464 | di-n-pentyl phthalate results in decreased expression of SRD5A1 mRNA | CTD | PMID:19560483 |
| diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of SRD5A1 mRNA | CTD | PMID:21551480 |
| doxorubicin | affects response to substance | ISO | RGD:736446 | 6480464 | SRD5A1 protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 |
| ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of SRD5A1 mRNA | CTD | PMID:17347304 |
| finasteride | decreases activity | EXP | | 6480464 | Finasteride results in decreased activity of SRD5A1 protein | CTD | PMID:20359488 |
| finasteride | decreases activity | ISO | RGD:736446 | 6480464 | Finasteride results in decreased activity of SRD5A1 protein | CTD | PMID:8689240 PMID:8142312 |
| finasteride | decreases activity | ISO | RGD:736446 | 6480464 | Finasteride results in decreased activity of SRD5A1 protein | CTD | PMID:8142312 PMID:8689240 |
| fluconazole | decreases expression | EXP | | 6480464 | Fluconazole results in decreased expression of SRD5A1 mRNA | CTD | PMID:16643972 |
| fluoroethene | decreases activity | ISO | RGD:736446 | 6480464 | vinyl fluoride analog results in decreased activity of SRD5A1 protein | CTD | PMID:8689240 |
| folic acid | multiple interactions | ISO | RGD:11341 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SRD5A1 gene | CTD | PMID:20938992 |
| indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of SRD5A1 mRNA | CTD | PMID:21396975 |
| indomethacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of SRD5A1 mRNA | CTD | PMID:18299717 |
| isotretinoin | decreases expression | ISO | RGD:736446 | 6480464 | Isotretinoin results in decreased expression of SRD5A1 mRNA | CTD | PMID:20436886 |
| L-methionine | multiple interactions | ISO | RGD:11341 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SRD5A1 gene | CTD | PMID:20938992 |
| lycopene | decreases expression | EXP | | 6480464 | lycopene results in decreased expression of SRD5A1 mRNA | CTD | PMID:15084515 |
| metoclopramide | increases expression | EXP | | 6480464 | Metoclopramide results in increased expression of SRD5A1 mRNA | CTD | PMID:18978642 |
| mitoxantrone | affects response to substance | ISO | RGD:736446 | 6480464 | SRD5A1 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SRD5A1 mRNA | CTD | PMID:17602206 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SRD5A1 mRNA | CTD | PMID:18164116 |
| perfluorooctanoic acid | decreases expression | ISO | RGD:11341 | 6480464 | perfluorooctanoic acid results in decreased expression of SRD5A1 mRNA | CTD | PMID:17681415 |
| perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of SRD5A1 mRNA | CTD | PMID:19162173 |
| phenobarbital | increases expression | ISO | RGD:11341 | 6480464 | Phenobarbital results in increased expression of SRD5A1 mRNA | CTD | PMID:19363144 |
| phenobarbital | decreases expression | ISO | RGD:11341 | 6480464 | Phenobarbital results in decreased expression of SRD5A1 mRNA | CTD | PMID:23091169 |
| piperidine | decreases activity | ISO | RGD:736446 | 6480464 | piperidine analog results in decreased activity of SRD5A1 protein | CTD | PMID:10896124 |
| piperidine | decreases activity | EXP | | 6480464 | piperidine analog results in decreased activity of SRD5A1 protein | CTD | PMID:10896124 |
| pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of SRD5A1 mRNA | CTD | PMID:19162173 |
| pirinixic acid | decreases expression | ISO | RGD:11341 | 6480464 | pirinixic acid results in decreased expression of SRD5A1 mRNA | CTD | PMID:20813756 |
| progesterone | affects metabolic processing | ISO | RGD:11341 | 6480464 | SRD5A1 protein affects the metabolism of Progesterone | CTD | PMID:15555913 |
| progesterone | affects metabolic processing | EXP | | 6480464 | SRD5A1 protein affects the metabolism of Progesterone | CTD | PMID:15261307 |
| progesterone | decreases activity | EXP | | 6480464 | Progesterone analog results in decreased activity of SRD5A1 protein | CTD | PMID:20359488 |
| propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of SRD5A1 mRNA | CTD | PMID:16643972 |
| propiconazole | increases expression | ISO | RGD:11341 | 6480464 | propiconazole results in increased expression of SRD5A1 mRNA | CTD | PMID:22334560 |
| Se-methyl-L-selenocysteine | multiple interactions | EXP | | 6480464 | [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein | CTD | PMID:19025659 |
| Se-methylselenocysteine | multiple interactions | EXP | | 6480464 | [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein | CTD | PMID:19025659 |
| sulpiride | increases expression | EXP | | 6480464 | Sulpiride results in increased expression of SRD5A1 mRNA | CTD | PMID:18978642 |
| testosterone | multiple interactions | ISO | RGD:736446 | 6480464 | SRD5A1 promotes the reaction [Testosterone results in increased expression of CPD mRNA] | CTD | PMID:21688280 |
| testosterone | increases expression | EXP | | 6480464 | Testosterone results in increased expression of SRD5A1 mRNA | CTD | PMID:22131296 |
| topotecan | affects response to substance | ISO | RGD:736446 | 6480464 | SRD5A1 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 |
| tributylstannane | decreases activity | ISO | RGD:736446 | 6480464 | tributyltin results in decreased activity of SRD5A1 protein | CTD | PMID:12231121 |
| trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SRD5A1 mRNA | CTD | PMID:19448997 |
| vincaleukoblastine | affects response to substance | ISO | RGD:736446 | 6480464 | SRD5A1 protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 |
| zinc atom | increases expression | EXP | | 6480464 | Zinc results in increased expression of SRD5A1 mRNA | CTD | PMID:18172885 |
| zinc(0) | increases expression | EXP | | 6480464 | Zinc results in increased expression of SRD5A1 mRNA | CTD | PMID:18172885 |