Gene: F2r (coagulation factor II (thrombin) receptor) Rattus norvegicus
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Symbol: F2r
Name: coagulation factor II (thrombin) receptor
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); G-protein coupled receptor activity (ortholog); INVOLVED IN activation of MAPKK activity; establishment of synaptic specificity at neuromuscular junction; G-protein coupled receptor signaling pathway; PARTICIPATES IN G protein mediated signaling pathway; protease mediated signaling via protease-activated receptor 1; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH abnormal nociception after inflammation; ASSOCIATED WITH Brain Edema; brain edema; Brain Ischemia; FOUND IN neuromuscular junction; plasma membrane; postsynaptic membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coagulation factor II receptor; MGC93622; PAR-1; Par1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; TRGPC
Orthologs:
Homo sapiens (human) : F2R (coagulation factor II thrombin receptor)  HGNC
Mus musculus (house mouse) : F2r (coagulation factor II (thrombin) receptor)  MGI
Chinchilla lanigera (long-tailed chinchilla) : F2r (coagulation factor II thrombin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : F2R (coagulation factor II thrombin receptor)
Canis lupus familiaris (dog) : F2R (coagulation factor II thrombin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F2r (coagulation factor II thrombin receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0226,118,760 - 26,135,340 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0245,254,489 - 45,257,761 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4225,985,800 - 25,989,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1225,906,181 - 25,909,441 (-)NCBI
Celera222,933,182 - 22,949,696 (-)NCBI
Cytogenetic Map2q12NCBImapview
RH 3.4 Map213.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on F2r
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RGD Object Information
RGD ID: 2586
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-06-06
Status: ACTIVE