Scg5 (secretogranin V) - Rat Genome Database

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Gene: Scg5 (secretogranin V) Rattus norvegicus
Analyze
Symbol: Scg5
Name: secretogranin V
RGD ID: 3669
Description: Predicted to enable enzyme inhibitor activity and unfolded protein binding activity. Predicted to be involved in intracellular protein transport; peptide hormone processing; and regulation of hormone secretion. Predicted to be located in secretory granule. Predicted to be active in nucleus. Orthologous to human SCG5 (secretogranin V); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 7B2; neuroendocrine protein 7B2; secretogranin V (7B2 protein); secretogranin-5; secretory granule endocrine protein I; secretory granule neuroendocrine protein 1; Secretory granule neuroendocrine protein 1 (7B2 protein); Secretory granule neuroendocrine, protein 1 (7B2 protein); Sgne1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,998,420 - 121,042,881 (-)NCBIGRCr8
mRatBN7.23100,544,101 - 100,588,558 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,544,099 - 100,588,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3104,171,047 - 104,215,378 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03112,770,077 - 112,814,414 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03110,459,966 - 110,504,303 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03105,235,065 - 105,279,475 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3105,235,050 - 105,279,462 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03111,811,718 - 111,856,212 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4399,629,194 - 99,674,523 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1399,525,619 - 99,570,949 (-)NCBI
Celera399,515,552 - 99,558,902 (-)NCBICelera
RH 3.4 Map3840.41RGD
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3,7-dihydropurine-6-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
diallyl trisulfide  (ISO)
dibutyl phthalate  (EXP)
diuron  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
furan  (EXP)
hydroquinone  (ISO)
malathion  (ISO)
mercaptopurine  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
mitomycin C  (ISO)
monosodium L-glutamate  (ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
PD 0325901  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
pirinixic acid  (ISO)
purine-6-thiol  (EXP)
quercetin  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular region  (IEA)
nucleus  (IEA,ISO)
secretory granule  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4. Neuroendocrine protein 7B2 can be inactivated by phosphorylation within the secretory pathway. Lee SN, etal., J Biol Chem. 2006 Feb 10;281(6):3312-20. Epub 2005 Nov 14.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12. Cloning and characterization of the rat complementary deoxyribonucleic acid and gene encoding the neuroendocrine peptide 7B2. Waldbieser GC, etal., Endocrinology 1991 Jun;128(6):3228-36.
Additional References at PubMed
PMID:6514132   PMID:7913882   PMID:8016065   PMID:9348280   PMID:10089884   PMID:11439082   PMID:15489334   PMID:21805245   PMID:25002582   PMID:27914912  


Genomics

Comparative Map Data
Scg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,998,420 - 121,042,881 (-)NCBIGRCr8
mRatBN7.23100,544,101 - 100,588,558 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,544,099 - 100,588,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3104,171,047 - 104,215,378 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03112,770,077 - 112,814,414 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03110,459,966 - 110,504,303 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03105,235,065 - 105,279,475 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3105,235,050 - 105,279,462 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03111,811,718 - 111,856,212 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4399,629,194 - 99,674,523 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1399,525,619 - 99,570,949 (-)NCBI
Celera399,515,552 - 99,558,902 (-)NCBICelera
RH 3.4 Map3840.41RGD
Cytogenetic Map3q35NCBI
SCG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381532,641,710 - 32,697,092 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1532,641,676 - 32,697,098 (+)EnsemblGRCh38hg38GRCh38
GRCh371532,933,911 - 32,989,293 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361530,721,252 - 30,776,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341530,721,251 - 30,776,590NCBI
Celera159,735,550 - 9,791,154 (+)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef159,796,189 - 9,851,652 (+)NCBIHuRef
CHM1_11533,051,914 - 33,107,353 (+)NCBICHM1_1
T2T-CHM13v2.01530,438,200 - 30,493,619 (+)NCBIT2T-CHM13v2.0
Scg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392113,606,708 - 113,659,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2113,606,707 - 113,659,466 (-)EnsemblGRCm39 Ensembl
GRCm382113,776,313 - 113,829,091 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2113,776,362 - 113,829,121 (-)EnsemblGRCm38mm10GRCm38
MGSCv372113,616,470 - 113,669,248 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362113,577,206 - 113,629,965 (-)NCBIMGSCv36mm8
Celera2114,909,627 - 114,958,933 (-)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.45NCBI
Scg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554161,866,997 - 1,914,640 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554161,867,848 - 1,914,505 (-)NCBIChiLan1.0ChiLan1.0
SCG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21621,409,656 - 21,465,388 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11526,131,284 - 26,187,027 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01511,136,920 - 11,192,606 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11529,974,633 - 30,030,291 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1529,974,633 - 30,030,291 (+)Ensemblpanpan1.1panPan2
SCG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1302,261,144 - 2,315,315 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl302,261,189 - 2,315,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha302,310,629 - 2,364,774 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0302,373,662 - 2,427,835 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl302,373,665 - 2,427,885 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1302,310,404 - 2,364,530 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0302,409,276 - 2,463,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0302,537,616 - 2,591,809 (-)NCBIUU_Cfam_GSD_1.0
Scg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864080,784,633 - 80,839,707 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366731,311,861 - 1,367,237 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366731,312,183 - 1,367,205 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1136,525,944 - 136,593,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11136,525,920 - 136,590,021 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21152,695,828 - 152,711,796 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12650,182,966 - 50,243,284 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2650,189,473 - 50,243,282 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604890,640,439 - 90,694,840 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248041,660,371 - 1,711,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scg5
122 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:50
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000010679
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat

Markers in Region
RH94440  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23100,544,122 - 100,544,280 (+)MAPPERmRatBN7.2
Rnor_6.03105,235,087 - 105,235,244NCBIRnor6.0
Rnor_5.03111,811,743 - 111,811,900UniSTSRnor5.0
RGSC_v3.4399,629,212 - 99,629,369UniSTSRGSC3.4
Celera399,515,570 - 99,515,727UniSTS
RH 3.4 Map3840.41UniSTS
Cytogenetic Map3q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7 68 1
Low 3 31 19 10 18 10 3 3 6 35 36 11 3
Below cutoff 12 30 30 1 30 5 7 3 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010679   ⟹   ENSRNOP00000010679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,544,099 - 100,588,463 (-)Ensembl
Rnor_6.0 Ensembl3105,235,050 - 105,279,462 (-)Ensembl
RefSeq Acc Id: NM_013175   ⟹   NP_037307
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,998,420 - 121,042,795 (-)NCBI
mRatBN7.23100,544,102 - 100,588,473 (-)NCBI
Rnor_6.03105,235,069 - 105,279,399 (-)NCBI
Rnor_5.03111,811,718 - 111,856,212 (-)NCBI
RGSC_v3.4399,629,194 - 99,674,523 (-)RGD
Celera399,515,552 - 99,558,902 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234701   ⟹   XP_006234763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,998,420 - 121,042,881 (-)NCBI
mRatBN7.23100,544,101 - 100,588,558 (-)NCBI
Rnor_6.03105,235,065 - 105,279,475 (-)NCBI
Rnor_5.03111,811,718 - 111,856,212 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_037307   ⟸   NM_013175
- Peptide Label: precursor
- UniProtKB: P27682 (UniProtKB/Swiss-Prot),   G3V714 (UniProtKB/TrEMBL),   A6HP67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234763   ⟸   XM_006234701
- Peptide Label: isoform X1
- UniProtKB: P27682 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010679   ⟸   ENSRNOT00000010679

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P27682-F1-model_v2 AlphaFold P27682 1-210 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692296
Promoter ID:EPDNEW_R2821
Type:multiple initiation site
Name:Scg5_1
Description:secretogranin V
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03105,279,399 - 105,279,459EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3669 AgrOrtholog
BioCyc Gene G2FUF-48360 BioCyc
Ensembl Genes ENSRNOG00000007542 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055002745 UniProtKB/Swiss-Prot
  ENSRNOG00060020133 UniProtKB/Swiss-Prot
  ENSRNOG00065015742 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010679 ENTREZGENE
  ENSRNOT00000010679.7 UniProtKB/TrEMBL
  ENSRNOT00055004321 UniProtKB/Swiss-Prot
  ENSRNOT00060034840 UniProtKB/Swiss-Prot
  ENSRNOT00065026142 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918342 IMAGE-MGC_LOAD
InterPro Secretogranin_V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25719 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72901 IMAGE-MGC_LOAD
NCBI Gene 25719 ENTREZGENE
PANTHER NEUROENDOCRINE PROTEIN 7B2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12738 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Secretogranin_V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scg5 PhenoGen
RatGTEx ENSRNOG00000007542 RatGTEx
  ENSRNOG00055002745 RatGTEx
  ENSRNOG00060020133 RatGTEx
  ENSRNOG00065015742 RatGTEx
TIGR TC228445
UniProt 7B2_RAT UniProtKB/Swiss-Prot
  A6HP67 ENTREZGENE, UniProtKB/TrEMBL
  G3V714 ENTREZGENE, UniProtKB/TrEMBL
  P27682 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-26 Scg5  secretogranin V  Scg5  secretogranin V (7B2 protein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-02 Scg5  secretogranin V (7B2 protein)  Scg5  secretogranin V  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-12 Scg5  secretogranin V  Sgne1  secretory granule neuroendocrine protein 1  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-06-10 Sgne1  Secretory granule neuroendocrine, protein 1 (7B2 protein)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the pituitary and in brain 729678