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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Diisodecyl phthalate
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Accession:CHEBI:34709 term browser browse the term
Definition:A phthalate ester that has formula C28H46O4.
Synonyms:related_synonym: Formula=C28H46O4;   InChI=1S/C28H46O4/c1-23(2)17-11-7-5-9-15-21-31-27(29)25-19-13-14-20-26(25)28(30)32-22-16-10-6-8-12-18-24(3)4/h13-14,19-20,23-24H,5-12,15-18,21-22H2,1-4H3;   InChIKey=ZVFDTKUVRCTHQE-UHFFFAOYSA-N;   SMILES=CC(C)CCCCCCCOC(=O)c1ccccc1C(=O)OCCCCCCCC(C)C
 xref: CAS:26761-40-0;   KEGG:C14578
 xref_mesh: MESH:C042080


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Diisodecyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects activity ISO diisodecyl phthalate affects the activity of AHR protein CTD PMID:18294747 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 increases expression ISO diisodecyl phthalate results in increased expression of ASB11 mRNA CTD PMID:25270620 NCBI chr  X:30,014,485...30,037,808 JBrowse link
G Bach2 BTB domain and CNC homolog 2 decreases expression ISO diisodecyl phthalate results in decreased expression of BACH2 mRNA CTD PMID:25270620 NCBI chr 5:46,632,338...46,982,676 JBrowse link
G C1qb complement C1q B chain increases expression ISO diisodecyl phthalate results in increased expression of C1QB mRNA CTD PMID:25270620 NCBI chr 5:149,118,843...149,124,394 JBrowse link
G Ccdc141 coiled-coil domain containing 141 increases expression ISO diisodecyl phthalate results in increased expression of CCDC141 mRNA CTD PMID:25270620 NCBI chr 3:61,948,614...62,109,968 JBrowse link
G Ccdc83 coiled-coil domain containing 83 increases expression ISO diisodecyl phthalate results in increased expression of CCDC83 mRNA CTD PMID:25270620 NCBI chr 1:144,167,993...144,225,622 JBrowse link
G Ccng2 cyclin G2 increases expression ISO diisodecyl phthalate results in increased expression of CCNG2 mRNA CTD PMID:25270620 NCBI chr14:14,804,321...14,812,819 JBrowse link
G Cd28 Cd28 molecule increases expression ISO diisodecyl phthalate results in increased expression of CD28 mRNA CTD PMID:25270620 NCBI chr 9:62,166,324...62,194,674 JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression ISO diisodecyl phthalate results in decreased expression of CDO1 mRNA CTD PMID:16223563 NCBI chr18:39,432,473...39,447,253 JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO diisodecyl phthalate results in increased expression of CEBPB mRNA CTD PMID:29410257 NCBI chr 3:156,398,035...156,399,466 JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO diisodecyl phthalate results in increased expression of CELSR3 mRNA CTD PMID:25270620 NCBI chr 8:109,530,597...109,558,360 JBrowse link
G Cenpv centromere protein V decreases expression ISO diisodecyl phthalate results in decreased expression of CENPV mRNA CTD PMID:25270620 NCBI chr10:47,214,479...47,228,552 JBrowse link
G Chia chitinase, acidic decreases expression ISO diisodecyl phthalate results in decreased expression of CHIA1 mRNA CTD PMID:25270620 NCBI chr 2:193,614,374...193,656,532 JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO diisodecyl phthalate results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 3:77,491,195...77,593,300 JBrowse link
G Cryab crystallin, alpha B increases expression ISO diisodecyl phthalate results in increased expression of CRYAB mRNA CTD PMID:25270620 NCBI chr 8:51,093,441...51,099,161 JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO diisodecyl phthalate results in increased expression of CSF2RB mRNA CTD PMID:25270620 NCBI chr 7:109,876,919...109,901,589 JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP diisodecyl phthalate results in decreased expression of CYP11A1 mRNA; diisodecyl phthalate results in decreased expression of CYP11A1 protein CTD PMID:32387388 NCBI chr 8:58,422,807...58,434,342 JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP diisodecyl phthalate results in decreased expression of CYP11B2 mRNA CTD PMID:33983380 NCBI chr 7:106,808,559...106,814,048 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO diisodecyl phthalate results in increased expression of CYP7A1 mRNA CTD PMID:25270620 NCBI chr 5:19,376,979...19,386,676 JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO diisodecyl phthalate results in increased expression of DGKA mRNA CTD PMID:25270620 NCBI chr 7:1,148,734...1,175,324 JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO diisodecyl phthalate results in decreased expression of ELK4 mRNA CTD PMID:25270620 NCBI chr13:43,451,130...43,475,035 JBrowse link
G Eml6 EMAP like 6 increases expression ISO diisodecyl phthalate results in increased expression of EML6 mRNA CTD PMID:25270620 NCBI chr14:103,471,537...103,806,120 JBrowse link
G Eno3 enolase 3 increases expression ISO diisodecyl phthalate results in increased expression of ENO3 mRNA CTD PMID:25270620 NCBI chr10:55,370,531...55,375,921 JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 decreases expression ISO diisodecyl phthalate results in decreased expression of EPB41 mRNA CTD PMID:25270620 NCBI chr 5:144,110,010...144,264,037 JBrowse link
G Fam53a family with sequence similarity 53, member A decreases expression ISO diisodecyl phthalate results in decreased expression of FAM53A mRNA CTD PMID:25270620 NCBI chr14:77,088,178...77,124,395 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO diisodecyl phthalate results in increased expression of GAPDH mRNA CTD PMID:25270620 NCBI chr 4:157,962,312...157,967,158 JBrowse link
G Glrx glutaredoxin increases expression ISO diisodecyl phthalate results in increased expression of GLRX mRNA CTD PMID:25270620 NCBI chr 2:5,341,873...5,351,686 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of HMOX1 protein CTD PMID:27871981 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO diisodecyl phthalate results in increased expression of HPRT mRNA CTD PMID:25270620 NCBI chr  X:132,736,175...132,768,149 JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP diisodecyl phthalate results in decreased expression of HSD17B3 mRNA; diisodecyl phthalate results in decreased expression of HSD17B3 protein CTD PMID:32387388 NCBI chr17:1,027,229...1,058,554 JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression EXP diisodecyl phthalate results in decreased expression of HSD3B3 mRNA CTD PMID:33983380 NCBI chr 2:186,138,044...186,144,024 JBrowse link
G Ifitm10 interferon induced transmembrane protein 10 decreases expression ISO diisodecyl phthalate results in decreased expression of IFITM10 mRNA CTD PMID:25270620 NCBI chr 1:197,507,501...197,524,180 JBrowse link
G Il4 interleukin 4 multiple interactions ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]] CTD PMID:27871981 NCBI chr10:37,771,203...37,776,750 JBrowse link
G Insl3 insulin-like 3 decreases expression EXP diisodecyl phthalate results in decreased expression of INSL3 mRNA CTD PMID:32387388 NCBI chr16:18,398,682...18,400,566 JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO diisodecyl phthalate results in decreased expression of INTS6 mRNA CTD PMID:25270620 NCBI chr15:36,908,966...37,048,043 JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C increases expression ISO diisodecyl phthalate results in increased expression of ITPKC mRNA CTD PMID:25270620 NCBI chr 1:82,500,957...82,522,533 JBrowse link
G LOC100125368 zinc finger protein LOC100125368 decreases expression ISO diisodecyl phthalate results in decreased expression of ZFP961 mRNA CTD PMID:25270620 NCBI chr 7:8,037,649...8,060,640 JBrowse link
G Lrp8 LDL receptor related protein 8 decreases expression ISO diisodecyl phthalate results in decreased expression of LRP8 mRNA CTD PMID:25270620 NCBI chr 5:122,563,468...122,635,434 JBrowse link
G Lypla1 lysophospholipase 1 increases expression ISO diisodecyl phthalate results in increased expression of LYPLA1 mRNA CTD PMID:25270620 NCBI chr 5:14,679,605...14,708,774 JBrowse link
G Mcph1 microcephalin 1 decreases expression ISO diisodecyl phthalate results in decreased expression of MCPH1 mRNA CTD PMID:25270620 NCBI chr16:71,021,855...71,224,067 JBrowse link
G Morc1 MORC family CW-type zinc finger 1 increases expression ISO diisodecyl phthalate results in increased expression of MORC1 mRNA CTD PMID:25270620 NCBI chr11:52,178,769...52,384,255 JBrowse link
G Ms4a7 membrane spanning 4-domains A7 decreases expression ISO diisodecyl phthalate results in decreased expression of MS4A7 mRNA CTD PMID:25270620 NCBI chr 1:207,968,761...207,984,812 JBrowse link
G Nck1 NCK adaptor protein 1 increases expression ISO diisodecyl phthalate results in increased expression of NCK1 mRNA CTD PMID:25270620 NCBI chr 8:101,018,610...101,079,237 JBrowse link
G Net1 neuroepithelial cell transforming 1 increases expression ISO diisodecyl phthalate results in increased expression of NET1 mRNA CTD PMID:25270620 NCBI chr17:66,341,251...66,370,445 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein CTD PMID:27871981 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nkx2-1 NK2 homeobox 1 increases expression ISO diisodecyl phthalate results in increased expression of NKX2-1 mRNA CTD PMID:25270620 NCBI chr 6:73,996,601...74,001,483 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]] CTD PMID:27871981 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects binding
multiple interactions
ISO diisodecyl phthalate binds to NR1I2 protein
diisodecyl phthalate binds to and results in increased activity of NR1I2 protein
CTD PMID:27071811 PMID:33049310 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Numb NUMB, endocytic adaptor protein decreases expression ISO diisodecyl phthalate results in decreased expression of NUMB mRNA CTD PMID:25270620 NCBI chr 6:103,431,400...103,553,422 JBrowse link
G Omd osteomodulin decreases expression ISO diisodecyl phthalate results in decreased expression of OMD mRNA CTD PMID:25270620 NCBI chr17:15,060,217...15,068,441 JBrowse link
G Osbpl3 oxysterol binding protein-like 3 decreases expression ISO diisodecyl phthalate results in decreased expression of OSBPL3 mRNA CTD PMID:25270620 NCBI chr 4:79,346,583...79,523,523 JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 decreases expression ISO diisodecyl phthalate results in decreased expression of PAPSS1 mRNA CTD PMID:16223563 NCBI chr 2:220,040,338...220,114,399 JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression ISO diisodecyl phthalate results in decreased expression of PAPSS2 mRNA CTD PMID:16223563 NCBI chr 1:230,454,314...230,539,332 JBrowse link
G Pfkp phosphofructokinase, platelet increases expression ISO diisodecyl phthalate results in increased expression of PFKP mRNA CTD PMID:25270620 NCBI chr17:63,729,743...63,794,021 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding
increases activity
ISO diisodecyl phthalate binds to PPARA protein
diisodecyl phthalate results in increased activity of PPARA protein
CTD PMID:23843199 PMID:30203046 NCBI chr 7:116,832,405...116,900,878 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO diisodecyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
increases expression
multiple interactions
ISO diisodecyl phthalate binds to PPARG protein
diisodecyl phthalate results in increased expression of PPARG mRNA
diisodecyl phthalate binds to and results in increased activity of PPARG protein
CTD PMID:23843199 PMID:29410257 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression ISO diisodecyl phthalate results in decreased expression of PPP1R10 mRNA CTD PMID:25270620 NCBI chr20:2,822,995...2,838,125 JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor 6 decreases expression ISO diisodecyl phthalate results in decreased expression of RAPGEF6 mRNA CTD PMID:25270620 NCBI chr10:38,655,854...38,824,227 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein; Melatonin inhibits the reaction [[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein] CTD PMID:27871981 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Rsrp1 arginine and serine rich protein 1 increases expression ISO diisodecyl phthalate results in increased expression of RSRP1 mRNA CTD PMID:25270620 NCBI chr 5:147,147,774...147,151,523 JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO diisodecyl phthalate binds to RXRA protein CTD PMID:29410257 NCBI chr 3:10,989,832...11,076,366 JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO diisodecyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267 JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP diisodecyl phthalate results in decreased expression of SCARB1 mRNA CTD PMID:33983380 NCBI chr12:31,296,143...31,362,649 JBrowse link
G Selenot selenoprotein T increases expression ISO diisodecyl phthalate results in increased expression of SELENOT mRNA CTD PMID:25270620 NCBI chr 2:142,804,387...142,821,438 JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 decreases expression ISO diisodecyl phthalate results in decreased expression of SIPA1L1 mRNA CTD PMID:25270620 NCBI chr 6:101,839,351...102,118,408 JBrowse link
G Slc12a9 solute carrier family 12, member 9 decreases expression ISO diisodecyl phthalate results in decreased expression of SLC12A9 mRNA CTD PMID:25270620 NCBI chr12:19,368,990...19,385,881 JBrowse link
G Slc25a11 solute carrier family 25 member 11 increases expression ISO diisodecyl phthalate results in increased expression of SLC25A11 mRNA CTD PMID:25270620 NCBI chr10:55,358,163...55,360,278 JBrowse link
G Slc26a1 solute carrier family 26 member 1 increases expression ISO diisodecyl phthalate results in increased expression of SLC26A1 mRNA CTD PMID:25270620 NCBI chr14:1,040,565...1,045,851 JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO diisodecyl phthalate results in increased expression of SLC29A1 mRNA CTD PMID:25270620 NCBI chr 9:15,399,661...15,414,203 JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression EXP
ISO
diisodecyl phthalate results in increased expression of SLC5A5 mRNA CTD PMID:16257484 NCBI chr16:18,546,709...18,556,698 JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression EXP diisodecyl phthalate results in decreased expression of SOX9 mRNA; diisodecyl phthalate results in decreased expression of SOX9 protein CTD PMID:32387388 NCBI chr10:97,806,485...97,811,994 JBrowse link
G Srpk1 SRSF protein kinase 1 increases expression ISO diisodecyl phthalate results in increased expression of SRPK1 mRNA CTD PMID:25270620 NCBI chr20:6,645,809...6,682,448 JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP diisodecyl phthalate results in decreased expression of STAR mRNA; diisodecyl phthalate results in decreased expression of STAR protein CTD PMID:32387388 NCBI chr16:66,267,094...66,274,368 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 NCBI chr10:85,811,206...85,863,057 JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]] CTD PMID:27871981 NCBI chr10:85,785,537...85,809,869 JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]] CTD PMID:27871981 NCBI chr 7:63,480,229...63,497,551 JBrowse link
G Suox sulfite oxidase decreases expression ISO diisodecyl phthalate results in decreased expression of SUOX mRNA CTD PMID:16223563 NCBI chr 7:1,103,149...1,107,156 JBrowse link
G Tbr1 T-box brain transcription factor 1 increases expression ISO diisodecyl phthalate results in increased expression of TBR1 mRNA CTD PMID:25270620 NCBI chr 3:46,350,237...46,368,397 JBrowse link
G Tmem98 transmembrane protein 98 increases expression ISO diisodecyl phthalate results in increased expression of TMEM98 mRNA CTD PMID:25270620 NCBI chr10:65,796,173...65,807,082 JBrowse link
G Trim27 tripartite motif-containing 27 decreases expression ISO diisodecyl phthalate results in decreased expression of TRIM27 mRNA CTD PMID:25270620 NCBI chr17:43,538,282...43,550,633 JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]] CTD PMID:27871981 NCBI chr18:24,447,409...24,454,244 JBrowse link
G Tufm Tu translation elongation factor, mitochondrial increases expression ISO diisodecyl phthalate results in increased expression of TUFM mRNA CTD PMID:25270620 NCBI chr 1:181,073,788...181,077,395 JBrowse link
G Vwa5b2 von Willebrand factor A domain containing 5B2 increases expression ISO diisodecyl phthalate results in increased expression of VWA5B2 mRNA CTD PMID:25270620 NCBI chr11:80,306,067...80,323,220 JBrowse link
G Wnt7a Wnt family member 7A decreases expression EXP diisodecyl phthalate results in decreased expression of WNT7A mRNA CTD PMID:22112501 PMID:33983380 NCBI chr 4:123,863,108...123,908,981 JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 increases expression ISO diisodecyl phthalate results in increased expression of ZC3H10 mRNA CTD PMID:25270620 NCBI chr 7:973,415...977,742 JBrowse link
G Zfp217 zinc finger protein 217 increases expression ISO diisodecyl phthalate results in increased expression of ZFP217 mRNA CTD PMID:25270620 NCBI chr 3:158,890,464...158,931,148 JBrowse link
G Zfp316 zinc finger protein 316 decreases expression ISO diisodecyl phthalate results in decreased expression of ZFP316 mRNA CTD PMID:25270620 NCBI chr12:11,294,445...11,313,841 JBrowse link

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  CHEBI ontology 19762
    role 19708
      application 19396
        pharmaceutical 19294
          drug 19294
            hormone receptor modulator 18837
              endocrine disruptor 18625
                phthalate ester 7471
                  Diisodecyl phthalate 88
Path 2
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  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18611
                              organic divalent group 18602
                                organodiyl group 18602
                                  carbonyl group 18519
                                    carbonyl compound 18519
                                      carboxylic acid 18195
                                        aromatic carboxylic acid 11288
                                          benzoic acids 11259
                                            benzenedicarboxylic acid 7735
                                              phthalic acid 7471
                                                phthalate ester 7471
                                                  Diisodecyl phthalate 88
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