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Gene: Mcph1 (microcephalin 1) Rattus norvegicus
Symbol: Mcph1
Name: microcephalin 1
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including establishment of mitotic spindle orientation; neuronal stem cell population maintenance; and regulation of organelle organization. Human ortholog(s) of this gene implicated in breast cancer; endometrial cancer; microcephaly; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 1. Orthologous to human MCPH1 (microcephalin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH amphetamine; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC306594; microcephalin; microcephaly, primary autosomal recessive 1; RGD1560642; similar to microcephalin
Homo sapiens (human) : MCPH1 (microcephalin 1)  HGNC  Alliance
Mus musculus (house mouse) : Mcph1 (microcephaly, primary autosomal recessive 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcph1 (microcephalin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MCPH1 (microcephalin 1)
Canis lupus familiaris (dog) : MCPH1 (microcephalin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcph1 (microcephalin 1)
Sus scrofa (pig) : MCPH1 (microcephalin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01675,904,087 - 76,110,624 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,904,006 - 76,110,553 (-)Ensembl
Rnor_5.01675,508,903 - 75,716,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41675,839,877 - 76,026,968 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1668,871,372 - 69,069,330 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mcph1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560642
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.