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Gene: Mcph1 (microcephalin 1) Rattus norvegicus
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Symbol: Mcph1
Name: microcephalin 1
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including establishment of mitotic spindle orientation; neuronal stem cell population maintenance; and regulation of organelle organization. Human ortholog(s) of this gene implicated in breast cancer; endometrial cancer; microcephaly; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 1. Orthologous to human MCPH1 (microcephalin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH amphetamine; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC306594; microcephalin; microcephaly, primary autosomal recessive 1; RGD1560642; similar to microcephalin
Orthologs:
Homo sapiens (human) : MCPH1 (microcephalin 1)  HGNC  Alliance
Mus musculus (house mouse) : Mcph1 (microcephaly, primary autosomal recessive 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcph1 (microcephalin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MCPH1 (microcephalin 1)
Canis lupus familiaris (dog) : MCPH1 (microcephalin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcph1 (microcephalin 1)
Sus scrofa (pig) : MCPH1 (microcephalin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01675,904,087 - 76,110,624 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,904,006 - 76,110,553 (-)Ensembl
Rnor_5.01675,508,903 - 75,716,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41675,839,877 - 76,026,968 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1668,871,372 - 69,069,330 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mcph1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560642
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.