Gene: Mcph1 (microcephalin 1) Rattus norvegicus
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Symbol: Mcph1
Name: microcephalin 1
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN bone development (ortholog); cerebral cortex development (ortholog); establishment of mitotic spindle orientation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Developmental Disabilities (ortholog); FOUND IN cell (inferred); INTERACTS WITH atrazine; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
AGR Description: Predicted to have identical protein binding activity; predicted to be involved in several processes, including animal organ development, establishment of mitotic spindle orientation, and regulation of organelle organization; predicted to localize to the cell; orthologous to human MCPH1 (microcephalin 1).
Merged Description: Predicted to have identical protein binding activity; predicted to be involved in several processes, including animal organ development, establishment of mitotic spindle orientation, and regulation of organelle organization; predicted to localize to the cell; orthologous to human MCPH1 (microcephalin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH atrazine; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC306594; microcephalin; microcephaly, primary autosomal recessive 1; RGD1560642; similar to microcephalin
Orthologs:
Homo sapiens (human) : MCPH1 (microcephalin 1)  HGNC  Alliance
Mus musculus (house mouse) : Mcph1 (microcephaly, primary autosomal recessive 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcph1 (microcephalin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MCPH1 (microcephalin 1)
Canis lupus familiaris (dog) : MCPH1 (microcephalin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcph1 (microcephalin 1)
Sus scrofa (pig) : MCPH1 (microcephalin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01675,904,087 - 76,110,624 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01675,508,903 - 75,716,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41675,839,877 - 76,026,968 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1668,871,372 - 69,069,330 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mcph1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560642
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.