Prostatic Neoplasms - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Prostatic Neoplasms	go back to main search page
Accession:	DOID:9002304	browse the term
Definition:	Tumors or cancer of the PROSTATE.
Synonyms:	exact_synonym:	prostate neoplasm; prostate neoplasms; prostatic neoplasm
	primary_id:	MESH:D011471

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Genes (1266)

Prostatic Neoplasms

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aladin WD repeat nucleoporin

CTD Direct Evidence: marker/mechanism

NCBI chr11:49,424,469...49,432,082

G

ATP binding cassette subfamily C member 4 (PEL blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579

G

ATP binding cassette subfamily G member 5

CTD Direct Evidence: marker/mechanism

NCBI chr14:63,414,241...63,439,193
Ensembl chr14:63,413,691...63,438,917

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr12:4,863,100...4,892,204
Ensembl chr12:4,863,165...4,885,849

G

ABR activator of RhoGEF and GTPase

CTD Direct Evidence: marker/mechanism

NCBI chr16:732,556...947,329
Ensembl chr16:735,211...847,690

G

acetylcholinesterase (Cartwright blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr28:12,328,304...12,335,302
Ensembl chr28:12,331,039...12,335,076

G

acid phosphatase 3

a positive cis-element in the promoter involved in regulating prostate cell-specific expression of the gene

NCBI chr15:57,887,528...57,934,851
Ensembl chr15:57,887,365...57,934,707

G

acrosin binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr11:6,672,093...6,681,493
Ensembl chr11:6,672,312...6,681,198

G

acyl-CoA synthetase long chain family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr X:97,488,414...97,575,251

G

acyl-CoA synthetase medium chain family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:18,876,390...18,929,914
Ensembl chr 5:18,904,110...18,929,729

G

activin A receptor type 2A

DNA:polymorphism

NCBI chr10:33,223,902...33,311,257
Ensembl chr10:33,224,099...33,307,720

G

ADAM metallopeptidase domain 28

CTD Direct Evidence: marker/mechanism

NCBI chr 8:22,424,260...22,483,878
Ensembl chr 8:22,430,579...22,488,257

G

ADAM metallopeptidase domain 9

CTD Direct Evidence: marker/mechanism

NCBI chr 8:37,017,827...37,131,462
Ensembl chr 8:37,017,545...37,131,615

G

ADAM metallopeptidase with thrombospondin type 1 motif 8

CTD Direct Evidence: marker/mechanism

NCBI chr 1:121,465,341...121,491,301
Ensembl chr 1:121,465,883...121,489,200

G

acireductone dioxygenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:104,140,027...104,172,782
Ensembl chr14:104,139,952...104,172,271

G

adrenoceptor beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

G

anterior gradient 2, protein disulphide isomerase family member

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:25237833

NCBI chr21:41,311,250...41,324,806
Ensembl chr21:41,312,415...41,326,663

G

adenosylhomocysteinase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr21:97,823,901...98,033,724
Ensembl chr21:97,971,154...98,033,738

G

aryl hydrocarbon receptor

CTD Direct Evidence: marker/mechanism

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

G

A-kinase anchoring protein 13

CTD Direct Evidence: marker/mechanism

NCBI chr29:4,009,921...4,364,226
Ensembl chr29:4,106,732...4,359,516

G

AKT serine/threonine kinase 1

ClinVar Annotator: match by term: Prostate neoplasm

PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

G

AKT serine/threonine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

aminolevulinate dehydratase

CTD Direct Evidence: marker/mechanism

NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845

G

aldehyde dehydrogenase 1 family member A2

CTD Direct Evidence: marker/mechanism

NCBI chr26:25,439,159...25,557,199
Ensembl chr26:25,439,360...25,557,202

G

arachidonate 12-lipoxygenase, 12R type

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934

G

arachidonate 5-lipoxygenase

CTD Direct Evidence: marker/mechanism

NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331

G

arachidonate lipoxygenase 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,478,775...7,500,931
Ensembl chr16:7,478,793...7,500,428

G

alpha-methylacyl-CoA racemase

mRNA, protein:increased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:17173048 PMID:20003233 PMID:22919386 PMID:24763052

NCBI chr 4:33,221,777...33,244,829
Ensembl chr 4:33,225,754...33,244,836

G

ANTXR cell adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:28,345,849...28,499,818
Ensembl chr 7:28,375,899...28,499,522

G

annexin A1

CTD Direct Evidence: marker/mechanism

NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562

G

annexin A3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:26,999,136...27,060,783
Ensembl chr 7:26,999,012...27,061,692

G

annexin A4

CTD Direct Evidence: marker/mechanism

NCBI chr14:37,297,960...37,384,187
Ensembl chr14:37,297,652...37,344,884

G

amine oxidase copper containing 1

NCBI chr21:119,037,498...119,046,875
Ensembl chr21:119,038,356...119,047,279

G

APC regulator of WNT signaling pathway

CTD Direct Evidence: marker/mechanism

PMID:17363566 PMID:29610475

NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067

G

apurinic/apyrimidinic endodeoxyribonuclease 1

susceptibility

protein:increased expression, altered localization:prostate, cytoplasm
CTD Direct Evidence: marker/mechanism

PMID:11309329 PMID:16406883 PMID:29541389

RGD:2315665 RGD:2315666

NCBI chr29:20,978,878...20,981,393

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:100,400,093...100,469,234
Ensembl chr11:100,400,084...100,462,507

G

androgen receptor

onset

ClinVar Annotator: match by term: Prostate neoplasm

PMID:17906287 PMID:23779130 PMID:28492532

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

amphiregulin

protein:increased expression:prostate gland

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

G

arginase 2

CTD Direct Evidence: marker/mechanism

NCBI chr24:44,851,139...44,884,118
Ensembl chr24:44,851,175...44,883,853

G

Rho guanine nucleotide exchange factor 5

CTD Direct Evidence: marker/mechanism

NCBI chr21:112,993,339...113,021,237
Ensembl chr21:113,000,705...113,018,050

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167

NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672

G

AT-rich interaction domain 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:41,933,650...42,117,495
Ensembl chr11:42,028,083...42,118,892

G

AT-rich interaction domain 4A

CTD Direct Evidence: marker/mechanism

NCBI chr24:35,491,391...35,566,073

G

ADP ribosylation factor like GTPase 6 interacting protein 1

CTD Direct Evidence: marker/mechanism

G

ASH1 like histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr20:8,290,606...8,499,991
Ensembl chr20:8,322,504...8,500,129

G

ankyrin repeat, SAM and basic leucine zipper domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:86,042,400...86,108,247
Ensembl chr21:86,042,691...86,107,099

G

ATPase family AAA domain containing 3A

CTD Direct Evidence: marker/mechanism

NCBI chr20:129,965,964...129,987,866

G

activating transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr25:16,910,312...16,922,598

G

ATM serine/threonine kinase

CTD Direct Evidence: marker/mechanism
protein:increased expression:prostate gland

PMID:14983937 PMID:17502119 PMID:25415046 PMID:26098866 PMID:29610475

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

ATPase copper transporting beta

CTD Direct Evidence: marker/mechanism

NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077

G

ATR serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137

G

aurora kinase A

protein:increased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:15754349 PMID:16707419 PMID:17898866

RGD:2293877 RGD:2293883

NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395

G

aurora kinase B

NCBI chr16:7,571,255...7,583,034
Ensembl chr16:7,570,538...7,582,959

G

alpha-2-glycoprotein 1, zinc-binding

CTD Direct Evidence: marker/mechanism

NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363

G

beta-2-microglobulin

CTD Direct Evidence: marker/mechanism

NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809

G

beta-1,4-galactosyltransferase 4

CTD Direct Evidence: marker/mechanism

NCBI chr22:61,600,143...61,629,857
Ensembl chr22:61,604,044...61,630,420

G

BCL2 associated agonist of cell death

CTD Direct Evidence: marker/mechanism

PMID:17542986 PMID:17607361 PMID:19593445

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

G

BRCA1 associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740

G

BCL2 associated X, apoptosis regulator

CTD Direct Evidence: marker/mechanism

PMID:17542986 PMID:18317887

NCBI chr 6:42,186,028...42,193,105

G

bromodomain adjacent to zinc finger domain 2A

CTD Direct Evidence: marker/mechanism

NCBI chr11:52,545,183...52,585,822
Ensembl chr11:52,547,789...52,566,799

G

BCAR1 scaffold protein, Cas family member

CTD Direct Evidence: marker/mechanism

NCBI chr 5:60,709,409...60,749,071
Ensembl chr 5:60,707,006...60,732,882

G

brain enriched myelin associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,972,244...10,098,126
Ensembl chr 2:9,972,433...10,096,747

G

BCL2 apoptosis regulator

CTD Direct Evidence: marker/mechanism

PMID:16733517 PMID:18317887

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

G

bone gamma-carboxyglutamate protein

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

G

baculoviral IAP repeat containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr16:70,226,824...70,237,000

G

bone morphogenetic protein 7

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:19283074

NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944

G

bone morphogenetic protein receptor type 1B

CTD Direct Evidence: marker/mechanism

G

BCL2 interacting protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:124,570,958...124,586,002
Ensembl chr 9:124,568,695...124,585,980

G

B-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

PMID:25735316 PMID:29610475

NCBI chr21:109,495,525...109,690,261

G

BRCA1 DNA repair associated

CTD Direct Evidence: marker/mechanism

NCBI chr16:63,162,827...63,243,928

G

BRCA2 DNA repair associated

CTD Direct Evidence: marker/mechanism

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

G

bromodomain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chr 6:13,836,332...13,883,459
Ensembl chr 6:13,836,324...13,873,877

G

bromodomain and PHD finger containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:45,740,192...45,756,327
Ensembl chr22:45,740,351...45,756,390

G

basigin (Ok blood group)

NCBI chr 6:309,579...320,209
Ensembl chr 6:309,506...321,785

G

BTG anti-proliferation factor 2

protein:decreased expression:prostate gland

NCBI chr25:26,032,404...26,036,500
Ensembl chr25:26,034,632...26,036,538

G

calreticulin

CTD Direct Evidence: marker/mechanism

NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792

G

calcium/calmodulin dependent protein kinase kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:116,613,003...116,648,389
Ensembl chr11:116,615,996...116,653,261

G

calpain small subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,049,509...31,061,219
Ensembl chr 6:31,050,494...31,061,421

G

coactivator associated arginine methyltransferase 1

protein:increased expression:prostate gland

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

G

caspase 3

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

G

caspase 9

CTD Direct Evidence: marker/mechanism

NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930

G

castor zinc finger 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:120,986,451...121,144,311

G

caveolin 1

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:11751529 PMID:15948133 PMID:17786030 PMID:22159333

RGD:2289102 RGD:2289111

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

G

caveolin 2

CTD Direct Evidence: marker/mechanism

NCBI chr21:85,197,452...85,206,521
Ensembl chr21:85,197,537...85,206,588

G

chromobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:68,471,298...68,508,180

G

coiled-coil alpha-helical rod protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:41,319,392...41,334,661
Ensembl chr17:41,319,423...41,334,502

G

cyclin A2

severity

protein:increased expression:prostate gland

NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497

G

cyclin D1

disease_progression

CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:prostate gland

PMID:14968434 PMID:17606477

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

G

cyclin D2

CTD Direct Evidence: marker/mechanism

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

G

cyclin E1

disease_progression

mRNA, protein:increased expression:prostate gland

NCBI chr 6:24,879,923...24,888,985

G

cyclin H

CTD Direct Evidence: marker/mechanism

NCBI chr 4:81,373,812...81,392,454
Ensembl chr 4:81,373,994...81,392,326

G

CD276 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr26:9,772,948...9,794,395

G

CD9 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr11:6,236,449...6,275,904
Ensembl chr11:6,236,494...6,275,909

G

cell division cycle 27

CTD Direct Evidence: marker/mechanism

NCBI chr16:59,497,731...59,564,298
Ensembl chr16:59,497,713...59,564,480

G

cadherin 12

CTD Direct Evidence: marker/mechanism

NCBI chr 4:21,183,585...22,272,005

G

cadherin 13

CTD Direct Evidence: marker/mechanism

PMID:17288544 PMID:18264096

NCBI chr 5:68,048,655...69,213,102
Ensembl chr 5:68,451,894...69,211,534

G

cyclin dependent kinase 1

PMID:17460776 PMID:17575168

RGD:2711357 RGD:2756028

NCBI chr 9:70,475,736...70,492,947

G

cyclin dependent kinase 12

CTD Direct Evidence: marker/mechanism

NCBI chr16:66,612,238...66,709,437
Ensembl chr16:66,623,785...66,708,755

G

cyclin dependent kinase 2 associated protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:6,756,853...6,759,087
Ensembl chr 1:6,756,909...6,759,090

G

cyclin dependent kinase inhibitor 1A

CTD Direct Evidence: marker/mechanism

PMID:12727815 PMID:15598783

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

G

cyclin dependent kinase inhibitor 1B

severity

CTD Direct Evidence: marker/mechanism|therapeutic
protein:decreased expression:prostate gland

PMID:12727815 PMID:18006855 PMID:18415709 PMID:20932324 PMID:29610475

RGD:2293591 RGD:2293596

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

G

CUGBP Elav-like family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:10,534,623...11,395,516
Ensembl chr 9:11,080,404...11,388,136

G

centromere protein F

CTD Direct Evidence: marker/mechanism

NCBI chr25:14,914,805...14,972,811
Ensembl chr25:14,914,809...14,972,796

G

chromodomain helicase DNA binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr23:2,433,694...2,507,334
Ensembl chr23:2,432,461...2,507,704

G

chromodomain helicase DNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,274,634...7,300,831
Ensembl chr16:7,276,850...7,300,832

G

chromodomain helicase DNA binding protein 6

CTD Direct Evidence: marker/mechanism

NCBI chr 2:22,163,836...22,373,098
Ensembl chr 2:22,223,919...22,373,275

G

chromodomain helicase DNA binding protein 7

CTD Direct Evidence: marker/mechanism

NCBI chr 8:56,654,939...56,782,803
Ensembl chr 8:56,657,826...56,785,804

G

checkpoint kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

carbohydrate sulfotransferase 14

CTD Direct Evidence: marker/mechanism

NCBI chr26:42,538,380...42,540,588
Ensembl chr26:42,539,203...42,540,333

G

component of inhibitor of nuclear factor kappa B kinase complex

protein:increased expression:prostate gland

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

G

CDKN1A interacting zinc finger protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:9,939,984...9,961,913
Ensembl chr12:9,940,696...9,962,235

G

claudin 3

CTD Direct Evidence: marker/mechanism

NCBI chr28:9,301,312...9,303,496
Ensembl chr28:9,302,446...9,303,108

G

claudin 7

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,632,695...6,635,994
Ensembl chr16:6,630,412...6,635,327

G

claudin 9

CTD Direct Evidence: marker/mechanism

NCBI chr 5:2,755,023...2,757,879
Ensembl chr 5:2,756,747...2,757,400

G

chloride intracellular channel 4

CTD Direct Evidence: marker/mechanism

NCBI chr20:107,855,046...107,952,529

G

CLPTM1 like

CTD Direct Evidence: marker/mechanism

NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898

G

clusterin

CTD Direct Evidence: marker/mechanism

NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789

G

calponin 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:38,325,810...38,356,563
Ensembl chr20:38,325,848...38,356,760

G

CCR4-NOT transcription complex subunit 3

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167

NCBI chr 6:46,814,695...46,832,657
Ensembl chr 6:46,819,903...46,836,838

G

collagen type XV alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr12:40,355,643...40,483,794

G

collagen type V alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr12:3,301,643...3,507,300
Ensembl chr12:3,301,175...3,459,607

G

collagen type V alpha 3 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,033,298...9,092,061
Ensembl chr 6:9,033,287...9,091,826

G

catechol-O-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

G

copine 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:81,697,014...81,744,851
Ensembl chr 8:81,711,571...81,745,019

G

cAMP responsive element binding protein 3 like 4

CTD Direct Evidence: marker/mechanism

NCBI chr20:9,839,137...9,848,413
Ensembl chr20:9,838,085...9,845,287

G

CREB binding protein

CTD Direct Evidence: marker/mechanism

PMID:15378487 PMID:25735316

NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943

G

cellular repressor of E1A stimulated genes 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:61,472,601...61,485,568
Ensembl chr25:61,472,617...61,488,999

G

crystallin alpha B

CTD Direct Evidence: marker/mechanism

NCBI chr 1:103,258,715...103,263,274
Ensembl chr 1:103,257,347...103,261,990

G

crystallin lambda 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:567,937...704,109
Ensembl chr 3:567,931...688,388

G

colony stimulating factor 1 receptor

protein:increased expression:prostate gland

NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304

G

cysteine and glycine rich protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:27,908,426...27,932,107
Ensembl chr25:27,908,554...27,933,275

G

cystatin E/M

CTD Direct Evidence: marker/mechanism

NCBI chr 1:8,244,483...8,246,551
Ensembl chr 1:8,244,485...8,245,968

G

C-terminal binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:117,635,124...117,806,908

G

cytotoxic T-lymphocyte associated protein 4

NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344

G

catenin beta 1

CTD Direct Evidence: marker/mechanism

PMID:17363566 PMID:17638904 PMID:29610475

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

cathepsin B

CTD Direct Evidence: marker/mechanism

NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854

G

cathepsin D

CTD Direct Evidence: marker/mechanism

NCBI chr 1:1,570,163...1,581,857
Ensembl chr 1:1,570,069...1,581,833

G

cullin 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:110,425,895...110,541,431
Ensembl chr10:110,425,076...110,541,538

G

C-X-C motif chemokine ligand 12

CTD Direct Evidence: marker/mechanism

NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494

G

C-X-C motif chemokine ligand 8

CTD Direct Evidence: marker/mechanism

PMID:16606632 PMID:17606477

NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068

G

cytochrome P450 family 17 subfamily A member 1

CTD Direct Evidence: marker/mechanism

PMID:15538743 PMID:16424004 PMID:16859836 PMID:16998812 PMID:17592021

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

G

cytochrome P450 family 19 subfamily A member 1

CTD Direct Evidence: marker/mechanism

PMID:16424004 PMID:17704407

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

G

cytochrome P450 family 1 subfamily A member 1

CTD Direct Evidence: marker/mechanism

PMID:11275366 PMID:17919073

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

G

cytochrome P450 family 1 subfamily B member 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

G

cytochrome P450 family 2 subfamily C member 18

CTD Direct Evidence: marker/mechanism

NCBI chr 9:87,881,444...87,941,586

G

cytochrome P450 family 2 subfamily C member 19

CTD Direct Evidence: marker/mechanism

NCBI chr 9:87,981,300...88,025,007

G

cytochrome P450 family 2 subfamily D member 6

CTD Direct Evidence: marker/mechanism

NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513

G

cytochrome P450 family 2 subfamily E member 1

CTD Direct Evidence: marker/mechanism

NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211

G

cytochrome P450 family 3 subfamily A member 43

CTD Direct Evidence: marker/mechanism

NCBI chr28:13,217,123...13,256,859
Ensembl chr28:13,216,548...13,257,015

G

cytochrome P450 family 3 subfamily A member 5

CTD Direct Evidence: marker/mechanism

NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507

G

cytochrome P450 family 7 subfamily B member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:60,496,607...60,691,457
Ensembl chr 8:60,496,733...60,524,238

G

DAB2 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890

G

dystroglycan 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:10,864,058...10,934,179
Ensembl chr22:10,865,724...10,934,200

G

DDB1 and CUL4 associated factor 6

CTD Direct Evidence: marker/mechanism

NCBI chr25:60,968,836...61,109,235
Ensembl chr25:60,967,870...61,109,562

G

dicarbonyl and L-xylulose reductase

CTD Direct Evidence: marker/mechanism

NCBI chr16:73,923,170...73,925,025
Ensembl chr16:73,919,463...73,925,277

G

discoidin domain receptor tyrosine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:41,564,271...41,583,404
Ensembl chr17:41,564,992...41,575,682

G

defensin beta 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:6,643,753...6,652,209
Ensembl chr 8:6,643,556...6,651,699

G

delta 4-desaturase, sphingolipid 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:5,589,530...5,603,261
Ensembl chr25:5,589,383...5,603,227

G

dihydrodiol dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:42,170,856...42,180,973
Ensembl chr 6:42,170,873...42,181,015

G

DExH-box helicase 30

CTD Direct Evidence: marker/mechanism

NCBI chr22:9,191,527...9,239,445
Ensembl chr22:9,206,175...9,239,372

G

diablo IAP-binding mitochondrial protein

CTD Direct Evidence: therapeutic

NCBI chr11:117,555,328...117,580,419
Ensembl chr11:117,552,145...117,579,553

G

DnaJ heat shock protein family (Hsp40) member C10

CTD Direct Evidence: marker/mechanism

NCBI chr10:68,243,867...68,296,818
Ensembl chr10:68,244,091...68,295,301

G

DnaJ heat shock protein family (Hsp40) member C3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:74,474,643...74,582,942
Ensembl chr 3:74,474,548...74,579,048

G

deoxyribonuclease 1 like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:2,130,879...2,133,817
Ensembl chr 5:2,131,854...2,133,524

G

DNA methyltransferase 1

treatment

CTD Direct Evidence: marker/mechanism

PMID:20584988 PMID:22581815 PMID:24038143

RGD:9588628 RGD:9588671

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

DNA methyltransferase 3 beta

CTD Direct Evidence: marker/mechanism

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

G

DOT1 like histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:1,962,077...2,030,732
Ensembl chr 6:1,962,279...2,026,455

G

ELL associated factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:58,966,640...59,025,158
Ensembl chr22:58,974,409...59,025,143

G

EGF containing fibulin extracellular matrix protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:8,384,212...8,391,501
Ensembl chr 1:8,385,020...8,390,889

G

epidermal growth factor

CTD Direct Evidence: marker/mechanism

NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516

G

epidermal growth factor receptor

ClinVar Annotator: match by term: Prostate neoplasm

PMID:23485129 PMID:25157968

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

G

early growth response 1

CTD Direct Evidence: marker/mechanism

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

G

EH domain binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:43,971,400...44,293,615
Ensembl chr14:43,971,261...44,292,365

G

ETS homologous factor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:30,591,880...30,651,077
Ensembl chr 1:30,591,273...30,622,803

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr15:4,164,795...4,228,593
Ensembl chr15:4,164,838...4,228,651

G

EI24 autophagy associated transmembrane protein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:116,711,922...116,727,208
Ensembl chr 1:116,714,578...116,726,216

G

eukaryotic translation initiation factor 2 alpha kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:70,246,081...70,290,851
Ensembl chr14:70,247,168...70,296,463

G

eukaryotic translation initiation factor 3 subunit A

CTD Direct Evidence: marker/mechanism

NCBI chr 9:111,828,858...111,887,546
Ensembl chr 9:111,830,988...111,887,518

G

eukaryotic translation initiation factor 3 subunit H

CTD Direct Evidence: marker/mechanism

NCBI chr 8:111,283,184...111,390,835

G

elaC ribonuclease Z 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:12,328,864...12,353,916
Ensembl chr16:12,329,300...12,353,872

G

epithelial membrane protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:13,099,213...13,119,492
Ensembl chr11:13,114,132...13,119,541

G

epithelial membrane protein 3 (MAM blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 6:41,591,145...41,596,723
Ensembl chr 6:41,591,020...41,596,951

G

ectonucleotide pyrophosphatase/phosphodiesterase family member 5

CTD Direct Evidence: marker/mechanism

NCBI chr17:26,082,427...26,091,526
Ensembl chr17:26,082,451...26,092,900

G

epithelial cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr14:59,815,128...59,832,360
Ensembl chr14:59,815,064...59,832,229

G

epoxide hydrolase 1

CTD Direct Evidence: marker/mechanism

PMID:17919073 PMID:21716162 PMID:24763052

NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535

G

EPS8 signaling adaptor L3

CTD Direct Evidence: marker/mechanism

NCBI chr20:23,780,116...23,795,946
Ensembl chr20:23,781,999...23,795,989

G

erb-b2 receptor tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

PMID:11222871 PMID:16984552 PMID:17363613

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

G

erb-b2 receptor tyrosine kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028

G

ERCC excision repair 1, endonuclease non-catalytic subunit

disease_progression

NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967

G

ERCC excision repair 2, TFIIH core complex helicase subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073

G

ETS2 repressor factor

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,452,604...36,460,188
Ensembl chr 6:36,452,577...36,460,122

G

ETS transcription factor ERG

CTD Direct Evidence: marker/mechanism

PMID:17173048 PMID:18798265 PMID:19396168 PMID:25735316 PMID:27223260 More...

NCBI chr 2:82,327,088...82,611,341
Ensembl chr 2:82,326,767...82,447,228

G

endoplasmic reticulum protein 29

CTD Direct Evidence: marker/mechanism

NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499

G

endoplasmic reticulum protein 44

CTD Direct Evidence: marker/mechanism

NCBI chr12:39,333,924...39,448,994
Ensembl chr12:39,333,944...39,448,535

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:17176215

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G

estrogen receptor 2

disease_progression

CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:prostate gland

PMID:15046698 PMID:16220300 PMID:16921512 PMID:17132221 PMID:17639508 More...

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G

ETS variant transcription factor 1

CTD Direct Evidence: marker/mechanism

PMID:17173048 PMID:17671502 PMID:27783944

NCBI chr21:44,090,290...44,187,741
Ensembl chr21:44,090,482...44,185,142

G

ETS variant transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:6,736,208...6,753,576
Ensembl chr20:6,736,327...6,753,544

G

ETS variant transcription factor 4

CTD Direct Evidence: marker/mechanism

PMID:17173048 PMID:27783944

NCBI chr16:62,864,628...62,883,574
Ensembl chr16:62,865,275...62,883,563

G

ETS variant transcription factor 5

CTD Direct Evidence: marker/mechanism

NCBI chr15:3,313,331...3,376,024
Ensembl chr15:3,316,585...3,373,708

G

EWS RNA binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:12,138,279...12,169,771

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

PMID:17003774 PMID:17173048 PMID:21903722

NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573

G

ezrin

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:17566973 PMID:24763052

NCBI chr13:86,342,954...86,399,827
Ensembl chr13:86,344,051...86,370,622

G

Fas associated factor family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr23:78,421,558...78,515,671
Ensembl chr23:78,456,545...78,516,245

G

Fas ligand

CTD Direct Evidence: therapeutic

NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251

G

fibulin 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:27,962,669...28,061,356
Ensembl chr19:27,962,642...28,061,364

G

fibulin 5

CTD Direct Evidence: marker/mechanism

NCBI chr24:69,626,498...69,703,146
Ensembl chr24:69,626,339...69,703,108

G

F-box protein 44

CTD Direct Evidence: marker/mechanism

NCBI chr20:120,128,422...120,137,081
Ensembl chr20:120,127,750...120,136,395

G

fibroblast growth factor 10

CTD Direct Evidence: marker/mechanism

NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432

G

fibroblast growth factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:70,089,394...70,157,423

G

fibroblast growth factor 6

mRNA,protein:increased expression:prostate

NCBI chr11:4,464,159...4,476,592
Ensembl chr11:4,464,171...4,473,916

G

fibroblast growth factor 8

disease_progression

protein:increased expression:prostate:expression of isoform FGF8b significantly associated with both stage (P=0.0004) and grade (P<0.0001)
mRNA,protein:increased expression:prostate:isoforms FGF8a and FGF8e
mRNA:decreased expression:prostate:expression negatively correlated with Gleason grade (p = 0.02)

PMID:10343609 PMID:11406643 PMID:12778074

RGD:2289338 RGD:2289340 RGD:2289343

NCBI chr 9:94,797,157...94,803,725
Ensembl chr 9:94,798,088...94,803,629

G

fibroblast growth factor receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456

G

fragile histidine triad diadenosine triphosphatase

CTD Direct Evidence: marker/mechanism

NCBI chr22:21,006,010...22,474,056

G

fms related receptor tyrosine kinase 1

protein:increased expression:prostate:expression in 15/15 (100%) of tumors examined, levels increased in neoplastic tissue relative to adjacent benign tissue
DNA:hypermethylation:promoter:methylated in 24/63 (38.1%) of cancer samples but 0/13 (0%) of benign prostate samples

PMID:10475375 PMID:12824880

RGD:2289936 RGD:2289963

NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967

G

fms related receptor tyrosine kinase 3

NCBI chr 3:7,117,579...7,222,600
Ensembl chr 3:7,116,947...7,222,849

G

forkhead box A1

CTD Direct Evidence: marker/mechanism

PMID:22610119 PMID:26457646 PMID:29295717 PMID:29610475 PMID:32690948

NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094

G

forkhead box A3

CTD Direct Evidence: marker/mechanism

NCBI chr 6:39,309,439...39,320,102
Ensembl chr 6:39,310,108...39,320,095

G

forkhead box C1

CTD Direct Evidence: marker/mechanism

NCBI chr17:70,533,048...70,536,555
Ensembl chr17:70,534,821...70,536,476

G

forkhead box O1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707

G

forkhead box P4

CTD Direct Evidence: marker/mechanism

NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849

G

frizzled class receptor 4

protein:increased expression:prostate gland

NCBI chr 1:78,164,243...78,199,296
Ensembl chr 1:78,188,630...78,198,187

G

growth arrest and DNA damage inducible alpha

CTD Direct Evidence: marker/mechanism

NCBI chr20:65,422,668...65,425,845
Ensembl chr20:65,422,451...65,425,840

G

polypeptide N-acetylgalactosaminyltransferase 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:51,237,150...51,284,301
Ensembl chr10:51,236,756...51,259,062

G

glucosaminyl (N-acetyl) transferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:87,502,202...87,506,171
Ensembl chr12:87,503,999...87,505,285

G

growth differentiation factor 15

CTD Direct Evidence: marker/mechanism

PMID:16775185 PMID:23996089

NCBI chr 6:16,853,397...16,861,924
Ensembl chr 6:16,852,971...16,861,964

G

gamma-glutamyltransferase 1

CTD Direct Evidence: marker/mechanism

G

growth hormone receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666

G

growth hormone releasing hormone receptor

disease_progression

DNA:transition:cds:p.D60G (mouse)

NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521

G

gap junction protein alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339

G

G protein subunit gamma 5

CTD Direct Evidence: marker/mechanism

NCBI chr20:48,862,904...48,866,425

G

glycine N-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr17:29,196,142...29,199,728
Ensembl chr17:29,196,321...29,198,947

G

golgin A4

CTD Direct Evidence: marker/mechanism

NCBI chr15:2,046,436...2,162,590
Ensembl chr15:2,046,156...2,162,235

G

glutathione peroxidase 3

CTD Direct Evidence: marker/mechanism

NCBI chr23:53,576,950...53,585,321

G

growth factor receptor bound protein 7

CTD Direct Evidence: marker/mechanism

NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300

G

glyoxylate and hydroxypyruvate reductase

CTD Direct Evidence: marker/mechanism

NCBI chr12:43,157,323...43,171,546
Ensembl chr12:43,156,840...43,171,532

G

gastrin releasing peptide receptor

CTD Direct Evidence: marker/mechanism

NCBI chr X:14,569,771...14,599,306
Ensembl chr X:14,570,453...14,599,258

G

glycogen synthase kinase 3 beta

CTD Direct Evidence: marker/mechanism

PMID:16421604 PMID:25246272

NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239

G

glutathione S-transferase C-terminal domain containing

CTD Direct Evidence: marker/mechanism

NCBI chr 7:53,750,836...53,881,057
Ensembl chr 7:53,750,628...53,883,001

G

glutathione S-transferase kappa 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:112,149,949...112,155,579
Ensembl chr21:112,149,970...112,155,300

G

glutathione S-transferase mu 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:23,797,794...23,802,910
Ensembl chr20:23,799,177...23,802,921

G

glutathione S-transferase omega 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:97,305,094...97,317,892

G

glutathione S-transferase pi 1

CTD Direct Evidence: marker/mechanism

PMID:11196146 PMID:15538743 PMID:17173048 PMID:19223546 PMID:22581815

NCBI chr 1:6,676,897...6,679,936

G

guanylyl cyclase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:7,578,125...7,589,196
Ensembl chr19:7,583,642...7,591,253

G

hydroxyacid oxidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:30,183,031...30,238,663
Ensembl chr 2:30,183,705...30,240,231

G

histone deacetylase 1

protein:increased expression:prostate gland

PMID:15042618 PMID:18212746

RGD:2306214 RGD:2306219

NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556

G

histone deacetylase 6

CTD Direct Evidence: marker/mechanism

NCBI chr X:45,927,625...45,951,636
Ensembl chr X:45,928,092...45,952,929

G

homocysteine inducible ER protein with ubiquitin like domain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:42,877,812...42,889,576
Ensembl chr 5:42,877,781...42,890,298

G

hypoxia inducible factor 1 subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

G

high mobility group box 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:119,440,089...119,442,806
Ensembl chr 7:119,440,468...119,443,578

G

high mobility group nucleosome binding domain 5

CTD Direct Evidence: marker/mechanism

NCBI chr X:70,103,170...70,201,472
Ensembl chr X:70,102,034...70,111,019

G

heme oxygenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971

G

HNF1 homeobox B

CTD Direct Evidence: marker/mechanism

PMID:18264096 PMID:18758462

NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088

G

heterogeneous nuclear ribonucleoprotein H1

CTD Direct Evidence: marker/mechanism

NCBI chr23:81,330,777...81,340,470
Ensembl chr23:81,330,351...81,339,882

G

heterogeneous nuclear ribonucleoprotein K

disease_progression

protein:increased expression:prostate gland (mouse)

NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743

G

homeobox B13

CTD Direct Evidence: marker/mechanism

PMID:23104005 PMID:24239177 PMID:24390282 PMID:26457646 PMID:32690948 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

homeobox B9

CTD Direct Evidence: marker/mechanism

NCBI chr16:69,027,926...69,047,020
Ensembl chr16:69,035,701...69,039,069

G

homeobox D3

CTD Direct Evidence: marker/mechanism

NCBI chr10:61,739,589...61,754,845
Ensembl chr10:61,744,967...61,748,121

G

15-hydroxyprostaglandin dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:120,589,646...120,620,864
Ensembl chr 7:120,588,462...120,621,016

G

hepsin

CTD Direct Evidence: marker/mechanism

PMID:15583422 PMID:16783571

NCBI chr 6:29,973,743...29,998,701
Ensembl chr 6:29,973,867...29,998,855

G

HRas proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637

G

hydroxysteroid 17-beta dehydrogenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:63,730,303...63,733,974
Ensembl chr16:63,728,777...63,732,411

G

hydroxysteroid 17-beta dehydrogenase 3

CTD Direct Evidence: marker/mechanism

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

G

heat shock protein 90 alpha family class B member 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:27,914,261...27,921,666
Ensembl chr17:27,911,013...27,921,251

G

heat shock protein 90 beta family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722

G

intercellular adhesion molecule 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263

G

inhibitor of DNA binding 3, HLH protein

CTD Direct Evidence: marker/mechanism

NCBI chr20:109,120,403...109,122,269
Ensembl chr20:109,120,691...109,123,210

G

isocitrate dehydrogenase (NADP(+)) 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975

G

insulin like growth factor 1

protein:increased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:16465378 PMID:19171036 PMID:19208208 PMID:24586243

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

G

insulin like growth factor 2 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116

G

insulin like growth factor binding protein 3

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:15318950 PMID:16000583 PMID:24586243

NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205

G

insulin like growth factor binding protein 6

CTD Direct Evidence: therapeutic

NCBI chr11:49,209,135...49,213,803
Ensembl chr11:49,209,136...49,213,858

G

insulin like growth factor binding protein 7

CTD Direct Evidence: therapeutic

NCBI chr 7:11,617,096...11,694,530

G

immunoglobulin superfamily member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 2:83,671,466...83,695,487

G

interleukin 10

CTD Direct Evidence: marker/mechanism

PMID:16284379 PMID:17999153 PMID:18174250

NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836

G

interleukin 16

CTD Direct Evidence: marker/mechanism

NCBI chr26:2,080,985...2,208,764
Ensembl chr26:2,077,228...2,208,431

G

interleukin 17 receptor C

CTD Direct Evidence: marker/mechanism

NCBI chr22:45,944,385...45,960,188
Ensembl chr22:45,944,669...45,960,164

G

interleukin 17 receptor D

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,416,143...18,489,855
Ensembl chr22:18,416,443...18,434,271

G

interleukin 18

CTD Direct Evidence: marker/mechanism

NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150

G

interleukin 1 receptor antagonist

CTD Direct Evidence: marker/mechanism

PMID:16106254 PMID:16284379

NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326

G

interleukin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969

G

interleukin 24

CTD Direct Evidence: therapeutic

PMID:14678967 PMID:21671747

NCBI chr25:22,453,579...22,460,361
Ensembl chr25:22,454,382...22,459,757

G

interleukin 27

CTD Direct Evidence: therapeutic

PMID:21801027 PMID:24028178

NCBI chr 5:26,348,559...26,358,028
Ensembl chr 5:26,348,848...26,356,360

G

interleukin 6

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:15672864 PMID:17196171 PMID:19011039 PMID:19240160 PMID:25970160

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

G

interleukin 6 cytokine family signal transducer

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167

NCBI chr 4:52,174,893...52,232,475
Ensembl chr 4:52,174,312...52,214,584

G

insulin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:1,965,128...1,969,090

G

insulin receptor

protein:increased expression:LNCaP tumors:increased tumor size and INSR levels in human tumor cells injected subcutaneously into mice on a high carbohydrate-high fat diet

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

G

integrator complex subunit 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:69,088,044...69,199,988
Ensembl chr 1:69,090,004...69,199,893

G

interleukin 1 receptor associated kinase 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:39,967,738...39,999,969
Ensembl chr11:39,977,636...39,999,847

G

insulin receptor substrate 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:112,748,283...112,812,368

G

integrin subunit beta 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857

G

inositol 1,4,5-trisphosphate receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842

G

intersectin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:58,298,529...58,543,297
Ensembl chr 2:58,301,399...58,543,281

G

intersectin 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:83,297,061...83,452,784
Ensembl chr14:83,297,259...83,453,335

G

influenza virus NS1A binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr25:44,083,696...44,104,760
Ensembl chr25:44,083,762...44,104,947

G

jade family PHD finger 2

CTD Direct Evidence: marker/mechanism

NCBI chr23:37,329,090...37,385,910
Ensembl chr23:37,330,498...37,386,035

G

Janus kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:68,122,134...68,253,361
Ensembl chr20:68,122,173...68,252,042

G

Janus kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

G

JAZF zinc finger 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:30,190,380...30,539,062

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chr16:44,955,617...44,970,136
Ensembl chr16:44,955,778...44,970,133

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

protein:increased expression:malignant tissues
Jun interacts with androgen receptor and ETV1 to mediate invasion

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

G

junction plakoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322

G

lysine acetyltransferase 5

protein:increased expression:pancreas, nucleus (human)

NCBI chr 1:8,528,097...8,544,512
Ensembl chr 1:8,526,788...8,544,972

G

lysine acetyltransferase 6A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:39,912,120...40,035,776
Ensembl chr 8:39,911,776...39,962,735

G

KDEL endoplasmic reticulum protein retention receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:41,640,954...41,649,740
Ensembl chr 6:41,640,636...41,650,080

G

lysine demethylase 6A

CTD Direct Evidence: marker/mechanism

NCBI chr X:42,053,272...42,291,013
Ensembl chr X:42,053,336...42,290,526

G

kelch like ECH associated protein 1

CTD Direct Evidence: marker/mechanism

PMID:24763052 PMID:29610475

NCBI chr 6:9,515,789...9,526,699
Ensembl chr 6:9,515,416...9,522,797

G

KLF transcription factor 15

CTD Direct Evidence: marker/mechanism

NCBI chr22:54,659,406...54,674,321
Ensembl chr22:54,659,703...54,674,368

G

KLF transcription factor 6

CTD Direct Evidence: marker/mechanism

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

G

kallikrein related peptidase 3

CTD Direct Evidence: marker/mechanism

PMID:12644816 PMID:15790600 PMID:16424004 PMID:16442593 PMID:16984552 More...

NCBI chr 6:43,905,684...43,911,925

G

kallikrein related peptidase 5

CTD Direct Evidence: marker/mechanism

NCBI chr 6:43,965,110...43,976,135
Ensembl chr 6:43,965,438...43,974,972

G

lysine methyltransferase 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:109,819,748...109,912,763
Ensembl chr 1:109,853,758...109,908,113

G

lysine methyltransferase 2C

CTD Direct Evidence: marker/mechanism

NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137

G

lysine methyltransferase 2D

CTD Direct Evidence: marker/mechanism

NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423

G

KRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

PMID:19117991 PMID:29610475

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

laminin subunit beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:10,523,763...10,535,733
Ensembl chr22:10,523,717...10,536,207

G

laminin subunit gamma 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:46,233,409...46,354,060
Ensembl chr25:46,231,780...46,353,557

G

lipid droplet associated hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr14:86,843,370...87,008,966
Ensembl chr14:86,866,459...87,010,009

G

lactate dehydrogenase B

CTD Direct Evidence: marker/mechanism

NCBI chr11:21,489,815...21,511,892
Ensembl chr11:21,488,814...21,511,938

G

leptin

CTD Direct Evidence: marker/mechanism

NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220

G

LIF receptor subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 4:37,307,753...37,385,489
Ensembl chr 4:37,314,347...37,362,137

G

lipopolysaccharide induced TNF factor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:11,023,158...11,099,133
Ensembl chr 5:11,021,717...11,059,149

G

lemur tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr28:14,961,397...15,067,423
Ensembl chr28:14,959,280...15,067,364

G

arylamine N-acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:16,302,296...16,315,406
Ensembl chr 8:16,314,446...16,315,318

G

carbonyl reductase [NADPH] 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:80,096,743...80,099,982

G

splicing factor U2AF 35 kDa subunit-like protein

CTD Direct Evidence: marker/mechanism

NCBI chr 2:86,949,910...86,964,655
Ensembl chr 2:86,950,056...86,964,579

G

growth regulating estrogen receptor binding 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:95,967,736...96,174,324
Ensembl chr14:95,967,699...96,019,165

G

heat shock 70 kDa protein 1A

CTD Direct Evidence: marker/mechanism

NCBI chr17:40,203,647...40,206,028
Ensembl chr17:40,203,936...40,205,858

G

uncharacterized LOC103221883

CTD Direct Evidence: marker/mechanism

PMID:16740699 PMID:29662167

NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027

G

histone H2B type 1-C/E/F/G/I

CTD Direct Evidence: marker/mechanism

NCBI chr17:46,035,117...46,035,587
Ensembl chr17:46,132,622...46,132,999

G

glutathione S-transferase Mu 1

CTD Direct Evidence: marker/mechanism

PMID:11275366 PMID:18304461 PMID:22564066

NCBI chr20:23,854,969...23,861,634

G

serine protease 2

protein:increased expression:serum

NCBI chr21:111,650,502...111,656,688
Ensembl chr21:111,651,681...111,656,699

G

fractalkine

CTD Direct Evidence: marker/mechanism

NCBI chr 5:43,310,711...43,323,533
Ensembl chr 5:43,310,753...43,323,529

G

cadherin-1

CTD Direct Evidence: marker/mechanism

PMID:16813949 PMID:22581815 PMID:29295717 PMID:29610475

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

PVR cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 6:38,127,864...38,141,612

G

kallikrein-2

CTD Direct Evidence: marker/mechanism

PMID:15643194 PMID:17085659

NCBI chr 6:43,916,304...43,927,165

G

N-deacetylase and N-sulfotransferase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:62,619,344...62,911,843
Ensembl chr 7:62,622,455...62,874,293

G

calcitonin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:49,946,574...49,956,010
Ensembl chr 1:49,951,694...49,954,092

G

mucin-4

CTD Direct Evidence: marker/mechanism

NCBI chr15:91,313,060...91,345,172

G

signal transducer and activator of transcription 5B

NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445

G

cytochrome P450 3A8

CTD Direct Evidence: marker/mechanism

NCBI chr28:13,297,566...13,330,023

G

lysophosphatidic acid receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:28,502,717...28,669,581
Ensembl chr12:28,503,354...28,669,795

G

lipoprotein lipase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:18,009,049...18,038,315
Ensembl chr 8:18,009,093...18,038,598

G

LDL receptor related protein 1B

CTD Direct Evidence: marker/mechanism

NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111

G

LDL receptor related protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:54,672,876...54,889,374
Ensembl chr10:54,711,517...54,889,208

G

leucine zipper tumor suppressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:18,315,243...18,377,492
Ensembl chr 8:18,315,130...18,324,345

G

mannose-6-phosphate receptor, cation dependent

CTD Direct Evidence: marker/mechanism

NCBI chr11:8,759,490...8,769,130
Ensembl chr11:8,757,799...8,768,379

G

macrophage immunometabolism regulator

CTD Direct Evidence: marker/mechanism

NCBI chr23:6,695,131...6,714,925
Ensembl chr23:6,712,171...6,712,791

G

mitotic arrest deficient 1 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

mesencephalic astrocyte derived neurotrophic factor

susceptibility

NCBI chr22:12,725,718...12,730,377
Ensembl chr22:12,726,308...12,730,587

G

mitogen-activated protein kinase kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

G

mitogen-activated protein kinase kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412

G

mitogen-activated protein kinase kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:19,396,377...19,427,617
Ensembl chr16:19,396,452...19,427,652

G

mitogen-activated protein kinase kinase 4

disease_progression

protein:increased expression:tumor:increased in high-grade prostatic intraepithelial neoplasias and tumor tissues (p<0.0001)
protein:decreased expression:tumor:significant inverse correlation between Gleason pattern and expression (p<0.01)
expression inhibits metastatic colonization of secondary sites by cancer cells in the AT6.1 model system

PMID:11306453 PMID:16322247 PMID:17577251

RGD:2293333 RGD:2293334 RGD:2293337

NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125

G

mitogen-activated protein kinase kinase 5

CTD Direct Evidence: marker/mechanism

NCBI chr26:15,694,760...15,956,814
Ensembl chr26:15,693,811...15,956,918

G

mitogen-activated protein kinase kinase 6

no_association

expression has no effect on metastatic colonization of secondary sites by cancer cells in the AT6.1 model system
protein:increased expression:tumor:increased in high-grade prostatic intraepithelial neoplasias and tumor tissues (p<0.0001)
CTD Direct Evidence: marker/mechanism

PMID:16322247 PMID:17577251 PMID:32512071

RGD:2293334 RGD:2293337

NCBI chr16:52,045,398...52,188,416
Ensembl chr16:52,057,784...52,187,997

G

mitogen-activated protein kinase kinase 7

disease_progression

expression inhibits metastatic colonization of secondary sites by cancer cells in the AT6.1 model system
protein:increased expression:tumor:increased in high-grade prostatic intraepithelial neoplasias and tumor tissues (p<0.0001)

PMID:16322247 PMID:17577251

RGD:2293334 RGD:2293337

NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398

G

mitogen-activated protein kinase kinase kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772

G

mitogen-activated protein kinase kinase kinase 7

no_association

based one the lack of correlation to loss of heterozygosity (LOH)
CTD Direct Evidence: marker/mechanism

PMID:12967473 PMID:17199135

NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832

G

mitogen-activated protein kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461

G

mitogen-activated protein kinase 9

CTD Direct Evidence: marker/mechanism

NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659

G

matrilin 4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:18,532,094...18,544,386

G

methyl-CpG binding domain protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:30,675,419...30,690,111
Ensembl chr18:30,675,653...30,685,946

G

methyl-CpG binding domain protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:26,714,610...26,785,028

G

membrane bound transcription factor peptidase, site 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:69,464,064...69,527,588
Ensembl chr 5:69,463,920...69,527,541

G

melanocortin 2 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr18:72,286,380...72,296,607
Ensembl chr18:72,288,224...72,289,105

G

MDM2 proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890

G

mediator complex subunit 12

CTD Direct Evidence: marker/mechanism

PMID:22610119 PMID:29610475

NCBI chr X:60,915,796...60,939,220
Ensembl chr X:60,915,703...60,937,677

G

MET proto-oncogene, receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093

G

MAX dimerization protein MGA

CTD Direct Evidence: marker/mechanism

NCBI chr26:41,215,424...41,381,828
Ensembl chr26:41,218,082...41,311,526

G

macrophage migration inhibitory factor

CTD Direct Evidence: marker/mechanism

NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757

G

mutL homolog 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393

G

membrane metalloendopeptidase

CTD Direct Evidence: marker/mechanism

NCBI chr15:35,577,460...35,681,730
Ensembl chr15:35,580,714...35,633,914

G

matrix metallopeptidase 13

CTD Direct Evidence: marker/mechanism

NCBI chr 1:94,322,473...94,370,665
Ensembl chr 1:94,322,979...94,334,747

G

matrix metallopeptidase 9

CTD Direct Evidence: marker/mechanism

NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712

G

myeloperoxidase

CTD Direct Evidence: marker/mechanism

NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671

G

MRE11 homolog, double strand break repair nuclease

CTD Direct Evidence: marker/mechanism

NCBI chr 1:85,615,448...85,694,247
Ensembl chr 1:85,610,819...85,694,269

G

mutS homolog 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:74,811,181...75,032,067
Ensembl chr 4:74,811,198...75,032,005

G

microseminoprotein beta

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:18264096 PMID:18264097

NCBI chr 9:41,796,948...41,810,373
Ensembl chr 9:41,803,922...41,810,276

G

macrophage scavenger receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:14,221,389...14,305,059
Ensembl chr 8:14,220,529...14,304,946

G

methylthioadenosine phosphorylase

CTD Direct Evidence: marker/mechanism

NCBI chr15:84,196,548...84,198,357
Ensembl chr12:57,997,427...58,050,241

G

methylenetetrahydrofolate reductase

CTD Direct Evidence: marker/mechanism

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

G

mechanistic target of rapamycin kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020

G

MAX interactor 1, dimerization protein

CTD Direct Evidence: marker/mechanism

NCBI chr 9:103,131,534...103,211,609
Ensembl chr 9:103,131,420...103,209,231

G

MYB binding protein 1a

CTD Direct Evidence: marker/mechanism

NCBI chr16:4,019,823...4,036,811
Ensembl chr16:4,016,222...4,036,782

G

MYC proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

PMID:17173048 PMID:23704919 PMID:29295717 PMID:32512071

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

MYCL proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr20:92,998,668...93,005,283
Ensembl chr20:92,999,219...93,005,344

G

myosin heavy chain 14

CTD Direct Evidence: marker/mechanism

NCBI chr 6:43,270,363...43,372,927
Ensembl chr 6:43,275,715...43,372,190

G

N-acetylglucosamine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr14:36,086,624...36,098,465
Ensembl chr14:36,082,137...36,096,914

G

N-acetyl-alpha-glucosaminidase

CTD Direct Evidence: marker/mechanism

NCBI chr16:63,735,411...63,744,365

G

N-acetyltransferase 2

CTD Direct Evidence: marker/mechanism

PMID:12618593 PMID:12622714 PMID:15717312 PMID:16083506

NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621

G

nibrin

CTD Direct Evidence: marker/mechanism

PMID:14973119 PMID:25415046

NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028

G

nuclear receptor coactivator 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

G

nuclear receptor coactivator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

G

nuclear receptor coactivator 3

CTD Direct Evidence: marker/mechanism

PMID:11927493 PMID:12237244

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

G

nuclear receptor coactivator 7

CTD Direct Evidence: marker/mechanism

NCBI chr13:47,787,740...47,949,814
Ensembl chr13:47,786,841...47,935,770

G

nuclear receptor corepressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:127,668,012...127,727,918
Ensembl chr 8:127,667,981...127,719,011

G

N-deacetylase and N-sulfotransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:57,561,349...57,574,145
Ensembl chr 9:57,563,820...57,569,756

G

nectin cell adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:38,320,791...38,361,419
Ensembl chr 6:38,320,933...38,361,742

G

NFE2 like bZIP transcription factor 2

CTD Direct Evidence: marker/mechanism

PMID:20124447 PMID:23441843

NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339

G

nuclear factor I C

CTD Direct Evidence: marker/mechanism

NCBI chr 6:3,128,553...3,232,485
Ensembl chr 6:3,135,480...3,227,601

G

nerve growth factor receptor

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:17409433 PMID:18056468

NCBI chr16:69,894,000...69,914,209
Ensembl chr16:69,894,139...69,912,189

G

NIPA like domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:108,225,452...108,281,448
Ensembl chr20:108,229,235...108,279,436

G

NK3 homeobox 1

CTD Direct Evidence: marker/mechanism

PMID:16817226 PMID:17173048 PMID:17202838 PMID:22610119 PMID:32690948

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

G

nucleolar protein 8

CTD Direct Evidence: marker/mechanism

NCBI chr12:102,823,206...102,851,484
Ensembl chr12:102,822,839...102,843,078

G

nitric oxide synthase 3

CTD Direct Evidence: marker/mechanism

PMID:12429631 PMID:12445681 PMID:16458450

NCBI chr21:119,174,829...119,196,840

G

NADPH oxidase 3

CTD Direct Evidence: marker/mechanism

NCBI chr13:82,972,005...83,033,457
Ensembl chr13:82,970,184...83,032,974

G

natriuretic peptide A

CTD Direct Evidence: therapeutic

NCBI chr20:119,942,412...119,946,211
Ensembl chr20:119,944,532...119,945,917

G

natriuretic peptide receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:31,984,712...32,062,593
Ensembl chr 4:31,986,217...32,062,199

G

NAD(P)H quinone dehydrogenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599

G

nuclear receptor subfamily 3 group C member 1

CTD Direct Evidence: marker/mechanism

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

G

neuropilin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:32,474,787...32,632,746
Ensembl chr 9:32,474,309...32,633,101

G

nucleobindin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:47,634,425...47,690,723
Ensembl chr 1:47,634,531...47,689,011

G

8-oxoguanine DNA glycosylase

CTD Direct Evidence: marker/mechanism

PMID:11956079 PMID:14634453

NCBI chr22:45,757,414...45,763,690

G

olfactomedin 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:3,028,681...3,063,754

G

one cut homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:22,248,353...22,296,290
Ensembl chr18:22,252,123...22,296,166

G

prolyl 4-hydroxylase subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr16:73,718,743...73,733,488
Ensembl chr16:73,718,656...73,733,892

G

p21 (RAC1) activated kinase 6

CTD Direct Evidence: marker/mechanism

NCBI chr26:42,737,848...42,798,960
Ensembl chr26:42,737,613...42,750,248

G

partner and localizer of BRCA2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:21,322,952...21,358,363
Ensembl chr 5:21,322,975...21,358,198

G

progestin and adipoQ receptor family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 5:2,708,807...2,713,104
Ensembl chr 5:2,709,245...2,713,256

G

par-3 family cell polarity regulator

CTD Direct Evidence: marker/mechanism

NCBI chr 9:33,396,738...34,104,479
Ensembl chr 9:33,396,246...33,803,997

G

poly(ADP-ribose) polymerase 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:3,350,798...3,405,040

G

PATJ crumbs cell polarity complex component

CTD Direct Evidence: marker/mechanism

NCBI chr20:70,910,594...71,300,877
Ensembl chr20:70,910,447...71,301,424

G

pro-apoptotic WT1 regulator

CTD Direct Evidence: marker/mechanism

NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072

G

paired box 6

CTD Direct Evidence: marker/mechanism

NCBI chr 1:33,386,165...33,414,605
Ensembl chr 1:33,392,970...33,414,587

G

protocadherin 8

CTD Direct Evidence: marker/mechanism

NCBI chr 3:30,602,449...30,610,656
Ensembl chr 3:30,602,321...30,606,926

G

pyruvate dehydrogenase E1 subunit alpha 1

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:29335542

NCBI chr X:17,804,123...17,820,087

G

protein disulfide isomerase family A member 3

CTD Direct Evidence: marker/mechanism

NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966

G

pyruvate dehydrogenase phosphatase catalytic subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:88,896,049...88,905,430
Ensembl chr 8:88,897,030...88,903,003

G

PDS5 cohesin associated factor A

CTD Direct Evidence: marker/mechanism

NCBI chr27:10,333,784...10,502,113
Ensembl chr27:10,388,334...10,487,029

G

PDZ domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:13,026,422...13,076,094
Ensembl chr20:13,040,475...13,079,241

G

PDZK1 interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:85,695,031...85,731,819

G

proenkephalin

CTD Direct Evidence: marker/mechanism

NCBI chr 8:52,458,113...52,463,933
Ensembl chr 8:52,457,904...52,463,859

G

phosphoglycerate mutase 2

CTD Direct Evidence: marker/mechanism

NCBI chr21:14,604,127...14,609,196
Ensembl chr21:14,606,401...14,609,158

G

progesterone receptor membrane component 1

CTD Direct Evidence: marker/mechanism

G

prohibitin 1

mRNA, protein:increased expression:prostate gland

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

G

phosphoglycerate dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr20:14,045,395...14,075,935
Ensembl chr20:14,045,346...14,076,177

G

phosphatidylinositol glycan anchor biosynthesis class P

CTD Direct Evidence: marker/mechanism

NCBI chr 2:81,026,551...81,048,686
Ensembl chr 2:81,040,993...81,048,661

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:29610475

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

CTD Direct Evidence: marker/mechanism

NCBI chr20:122,040,131...122,111,397
Ensembl chr20:122,041,963...122,078,504

G

phosphoinositide-3-kinase regulatory subunit 1

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167 PMID:33129824

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

G

phosphoinositide-3-kinase regulatory subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937

G

paired like homeodomain 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:95,266,257...95,278,333
Ensembl chr 9:95,266,582...95,268,139

G

plakophilin 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:214,986...223,958
Ensembl chr 1:215,874...224,015

G

plasminogen activator, urokinase

CTD Direct Evidence: marker/mechanism

PMID:11454671 PMID:16430655 PMID:17192053

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

G

plasminogen activator, urokinase receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 6:37,161,957...37,191,867

G

pleckstrin 2

CTD Direct Evidence: marker/mechanism

NCBI chr24:44,626,830...44,654,620
Ensembl chr24:44,622,248...44,653,976

G

PML nuclear body scaffold

CTD Direct Evidence: marker/mechanism

NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931

G

PMS1 homolog 1, mismatch repair system component

CTD Direct Evidence: marker/mechanism

NCBI chr10:75,305,129...75,392,193
Ensembl chr10:75,311,887...75,392,590

G

podocalyxin like

CTD Direct Evidence: marker/mechanism

NCBI chr21:100,139,902...100,194,013
Ensembl chr21:100,135,856...100,192,221

G

DNA polymerase kappa

CTD Direct Evidence: marker/mechanism

NCBI chr 4:69,842,887...69,948,285
Ensembl chr 4:69,872,752...69,948,249

G

paraoxonase 1

CTD Direct Evidence: marker/mechanism

PMID:12783936 PMID:15538743 PMID:21716162

NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875

G

peroxisome proliferator activated receptor alpha

CTD Direct Evidence: marker/mechanism

G

PPFIA binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:57,182,518...57,326,875
Ensembl chr 1:57,182,327...57,289,827

G

periplakin

CTD Direct Evidence: marker/mechanism

NCBI chr 5:4,554,837...4,610,427
Ensembl chr 5:4,555,682...4,610,278

G

protein phosphatase 2 regulatory subunit Balpha

CTD Direct Evidence: marker/mechanism

NCBI chr 8:24,390,751...24,485,657
Ensembl chr 8:24,390,781...24,487,195

G

protein phosphatase 3 catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 7:49,149,044...49,478,796
Ensembl chr 7:49,148,933...49,321,013

G

peroxiredoxin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:11,484,452...11,489,067
Ensembl chr 6:11,481,784...11,489,051

G

protein kinase cAMP-activated catalytic subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806

G

protein kinase C zeta

CTD Direct Evidence: marker/mechanism

NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818

G

protein kinase, DNA-activated, catalytic subunit

CTD Direct Evidence: marker/mechanism

PMID:17196815 PMID:25415046

NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541

G

prion protein (Kanno blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 2:33,368,020...33,384,556
Ensembl chr 2:33,369,629...33,370,366

G

paired related homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr25:58,347,686...58,423,454
Ensembl chr25:58,347,704...58,421,980

G

serine protease 8

disease_progression

mRNA:increased expression:prostate gland
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood

PMID:11173941 PMID:12518323 PMID:16541421

RGD:2292484 RGD:2292487

NCBI chr 5:27,820,898...27,827,873
Ensembl chr 5:27,817,830...27,824,926

G

prostate stem cell antigen

CTD Direct Evidence: marker/mechanism

NCBI chr 8:136,925,881...136,929,257

G

PSMC3 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr16:63,709,351...63,715,338
Ensembl chr16:63,709,982...63,714,804

G

phosphatase and tensin homolog

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:9371490 PMID:11175795 PMID:11854455 PMID:16421604 PMID:17173048 More...

RGD:1302553 RGD:2292497 RGD:2292510

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

prostaglandin-endoperoxide synthase 2

severity

CTD Direct Evidence: marker/mechanism
protein:altered localization
DNA:hypermethylation

PMID:10753955 PMID:14754878 PMID:15126378 PMID:16506214 PMID:17609663 More...

RGD:2300123 RGD:2300193

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

G

parathyroid hormone like hormone

CTD Direct Evidence: marker/mechanism

NCBI chr11:27,682,300...27,694,808
Ensembl chr11:27,682,338...27,694,898

G

protein tyrosine phosphatase receptor type C

CTD Direct Evidence: marker/mechanism

NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303

G

protein tyrosine phosphatase receptor type K

CTD Direct Evidence: marker/mechanism

NCBI chr13:45,062,273...45,619,939
Ensembl chr13:45,062,342...45,619,929

G

peptidyl-tRNA hydrolase 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:33,738,444...33,749,016
Ensembl chr16:33,748,336...33,748,909

G

pyrin and HIN domain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:4,967,123...5,006,172
Ensembl chr20:4,967,224...5,006,035

G

glutaminyl-tRNA synthetase 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:10,497,921...10,507,673
Ensembl chr22:10,497,658...10,507,325

G

RAB4B, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr 6:35,231,448...35,249,080
Ensembl chr 6:35,231,490...35,251,111

G

RAD23 homolog B, nucleotide excision repair protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:32,203,501...32,250,555
Ensembl chr12:32,204,893...32,250,570

G

Raf-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020

G

recombination activating 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:28,667,996...28,701,002

G

ralA binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:68,353,823...68,415,221
Ensembl chr18:68,391,245...68,413,555

G

ras related dexamethasone induced 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:16,529,075...16,531,085
Ensembl chr16:16,528,896...16,531,095

G

RB transcriptional corepressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546

G

REC8 meiotic recombination protein

CTD Direct Evidence: marker/mechanism

NCBI chr24:1,157,135...1,165,927

G

RELA proto-oncogene, NF-kB subunit

disease_progression

protein:altered localization, increased expression:nucleus, prostate gland

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

G

riboflavin kinase

CTD Direct Evidence: marker/mechanism

NCBI chr12:87,392,305...87,400,414
Ensembl chr12:87,394,190...87,400,083

G

regulatory factor X6

CTD Direct Evidence: marker/mechanism

NCBI chr13:56,889,160...56,948,304
Ensembl chr13:56,889,780...56,946,413

G

repulsive guidance molecule BMP co-receptor b

CTD Direct Evidence: marker/mechanism

NCBI chr23:2,339,567...2,368,239
Ensembl chr23:2,341,856...2,369,294

G

ring finger protein, LIM domain interacting

CTD Direct Evidence: marker/mechanism

NCBI chr X:64,178,159...64,205,759

G

relaxin 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:74,184,516...74,191,364
Ensembl chr12:74,186,116...74,190,540

G

ribonuclease A family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr29:21,216,021...21,233,306
Ensembl chr29:21,216,477...21,232,699

G

ribonuclease L

CTD Direct Evidence: marker/mechanism

PMID:16114055 PMID:17020975 PMID:27318894

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

ring finger protein 130

CTD Direct Evidence: marker/mechanism

NCBI chr23:81,647,146...81,794,893
Ensembl chr23:81,682,202...81,794,489

G

ring finger protein 31

CTD Direct Evidence: marker/mechanism

NCBI chr24:1,133,589...1,146,020
Ensembl chr24:1,133,723...1,142,943

G

ring finger protein 43

CTD Direct Evidence: marker/mechanism

NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107

G

roundabout guidance receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:97,178,093...98,363,647
Ensembl chr22:98,222,891...98,363,219

G

roundabout guidance receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:99,334,033...101,101,924

G

ribosomal protein L10

CTD Direct Evidence: marker/mechanism

G

ribosomal protein L11

CTD Direct Evidence: marker/mechanism

NCBI chr20:108,982,781...108,987,667
Ensembl chr20:108,981,723...108,987,734

G

ribosomal protein L12

CTD Direct Evidence: marker/mechanism

NCBI chr12:10,677,061...10,681,041

G

ribophorin II

CTD Direct Evidence: marker/mechanism

NCBI chr 2:26,503,344...26,563,958
Ensembl chr 2:26,503,597...26,564,142

G

regulation of nuclear pre-mRNA domain containing 2

CTD Direct Evidence: marker/mechanism

G

ribosomal protein S19

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,067,959...36,085,581

G

RAS related

CTD Direct Evidence: marker/mechanism

NCBI chr 6:42,810,411...42,815,504
Ensembl chr 6:42,810,339...42,815,479

G

retinoid X receptor alpha

protein:decreased expression:prostate
CTD Direct Evidence: marker/mechanism

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

G

sterile alpha motif domain containing 9

CTD Direct Evidence: marker/mechanism

NCBI chr21:55,895,799...55,913,845
Ensembl chr21:55,907,249...55,912,015

G

stromal cell derived factor 2 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761

G

selenoprotein P

CTD Direct Evidence: marker/mechanism

NCBI chr 4:41,544,098...41,556,152

G

selenoprotein S

CTD Direct Evidence: marker/mechanism

NCBI chr29:19,727,073...19,732,384
Ensembl chr29:19,726,451...19,732,375

G

SUMO specific peptidase 6

CTD Direct Evidence: marker/mechanism

NCBI chr13:315,000...427,549
Ensembl chr13:315,390...425,390

G

serine incorporator 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:19,299,852...19,325,448
Ensembl chr 2:19,299,828...19,321,466

G

serpin family A member 3

CTD Direct Evidence: marker/mechanism

NCBI chr24:72,388,948...72,415,746
Ensembl chr24:72,402,560...72,415,507

G

serpin family B member 10

CTD Direct Evidence: marker/mechanism

NCBI chr18:15,878,552...15,903,891
Ensembl chr18:15,878,191...15,894,609

G

serpin family E member 1

CTD Direct Evidence: marker/mechanism

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

G

serpin family F member 1

treatment

CTD Direct Evidence: therapeutic
human gene in a rat model

PMID:20360944 PMID:21671747

NCBI chr16:1,408,453...1,424,197

G

sestrin 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:86,426,258...86,486,465
Ensembl chr 1:86,427,988...86,486,477

G

SET domain containing 2, histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201

G

SET domain bifurcated histone lysine methyltransferase 1

CTD Direct Evidence: marker/mechanism

G

splicing factor 3b subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:82,901,908...82,952,094
Ensembl chr10:82,899,079...82,952,071

G

sex hormone binding globulin

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,002,380...7,012,170
Ensembl chr16:7,008,682...7,012,764

G

SIL1 nucleotide exchange factor

CTD Direct Evidence: marker/mechanism

NCBI chr23:41,611,360...41,855,632
Ensembl chr23:41,609,484...41,855,663

G

sirtuin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

G

solute carrier family 12 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr23:31,028,514...31,132,263
Ensembl chr23:31,029,026...31,132,289

G

solute carrier family 22 member 3

CTD Direct Evidence: marker/mechanism

NCBI chr13:87,971,305...88,076,468
Ensembl chr13:87,971,392...88,074,946

G

solute carrier family 26 member 4

CTD Direct Evidence: marker/mechanism

NCBI chr21:76,578,035...76,631,725
Ensembl chr21:76,578,665...76,633,165

G

solute carrier family 30 member 4

disease_progression

protein:decreased expression:prostate gland

NCBI chr26:37,692,164...37,732,102
Ensembl chr26:37,692,219...37,731,292

G

solute carrier family 31 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:26,307,308...26,348,701
Ensembl chr12:26,311,334...26,348,694

G

solute carrier family 39 member 1

CTD Direct Evidence: marker/mechanism

PMID:16700911 PMID:19208208

NCBI chr20:9,847,928...9,852,998
Ensembl chr20:9,847,968...9,853,413

G

solute carrier family 4 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr21:119,240,352...119,258,920
Ensembl chr21:119,241,490...119,263,193

G

solute carrier family 5 member 5

CTD Direct Evidence: therapeutic

PMID:12489024 PMID:14633711

NCBI chr 6:16,346,361...16,367,833

G

solute carrier family 6 member 20

CTD Direct Evidence: marker/mechanism

NCBI chr22:7,228,039...7,265,441
Ensembl chr22:7,228,517...7,265,031

G

solute carrier family 7 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:8,522,268...8,606,437
Ensembl chr 3:8,527,273...8,606,402

G

SMAD family member 4

disease_progression

NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:104,690,937...104,768,326
Ensembl chr X:104,690,689...104,768,298

G

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:42,468,551...42,552,493
Ensembl chr 7:42,498,601...42,553,661

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:12592389 PMID:15512801 PMID:17465268 PMID:17646272 PMID:18829485 More...

NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974

G

SRY-box transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:7,673,581...7,676,812
Ensembl chr15:7,674,867...7,675,826

G

Sp5 transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr10:56,244,579...56,247,770
Ensembl chr10:56,245,295...56,247,186

G

spermatogenesis associated 18

CTD Direct Evidence: marker/mechanism

NCBI chr 7:16,342,176...16,388,458
Ensembl chr 7:16,340,607...16,387,995

G

spen family transcriptional repressor

CTD Direct Evidence: marker/mechanism

NCBI chr20:116,359,981...116,458,156
Ensembl chr20:116,361,008...116,458,064

G

serine peptidase inhibitor Kazal type 1

CTD Direct Evidence: marker/mechanism

NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814

G

serine peptidase inhibitor Kazal type 5

CTD Direct Evidence: marker/mechanism

NCBI chr23:50,587,698...50,667,219
Ensembl chr23:50,592,412...50,663,302

G

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1

CTD Direct Evidence: marker/mechanism

NCBI chr23:39,676,750...40,192,565
Ensembl chr23:39,676,558...39,965,037

G

spondin 2

CTD Direct Evidence: marker/mechanism

NCBI chr27:47,609,170...47,615,507
Ensembl chr27:47,609,922...47,615,496

G

speckle type BTB/POZ protein

CTD Direct Evidence: marker/mechanism

PMID:22610119 PMID:29295717 PMID:29610475

NCBI chr16:69,990,554...70,073,241

G

secreted phosphoprotein 1

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

G

steroid 5 alpha-reductase 1

CTD Direct Evidence: marker/mechanism

PMID:17707058 PMID:18500220 PMID:20564326

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

G

steroid 5 alpha-reductase 2

CTD Direct Evidence: marker/mechanism

PMID:16998812 PMID:17136762 PMID:17823934 PMID:18306354 PMID:18500220

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

G

single stranded DNA binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:75,561,872...75,882,924
Ensembl chr 4:75,562,625...75,882,845

G

signal sequence receptor subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,844,461...7,856,869
Ensembl chr20:7,844,430...7,856,999

G

ST14 transmembrane serine protease matriptase

CTD Direct Evidence: marker/mechanism
protein:increased expression:prostate gland

PMID:17013881 PMID:18813126

NCBI chr 1:121,238,666...121,290,528
Ensembl chr 1:121,238,643...121,290,007

G

stabilin 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:98,780,148...98,953,871
Ensembl chr11:98,779,921...98,954,913

G

StAR related lipid transfer domain containing 10

CTD Direct Evidence: marker/mechanism

NCBI chr 1:63,993,578...64,032,849
Ensembl chr 1:63,991,312...64,020,610

G

StAR related lipid transfer domain containing 3

CTD Direct Evidence: marker/mechanism

PMID:17013881 PMID:17592021

NCBI chr16:66,503,544...66,530,214
Ensembl chr16:66,504,119...66,513,861

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism
protein:increased expression:prostate gland

PMID:14975756 PMID:16427044 PMID:18317887 PMID:25970160

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

G

STEAP4 metalloreductase

CTD Direct Evidence: marker/mechanism

NCBI chr21:60,653,504...60,680,414
Ensembl chr21:60,653,454...60,680,323

G

stathmin 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:106,866,719...106,873,314
Ensembl chr20:106,868,838...106,874,403

G

syntaxin 4

CTD Direct Evidence: marker/mechanism

NCBI chr 5:27,725,121...27,734,442
Ensembl chr 5:27,724,495...27,732,736

G

sulfotransferase family 1E member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:18,313,510...18,330,768
Ensembl chr 7:18,313,238...18,330,741

G

sulfotransferase family 2A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:41,160,707...41,175,382
Ensembl chr 6:41,159,978...41,175,300

G

sulfotransferase family 2B member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:41,809,654...41,852,685
Ensembl chr 6:41,810,049...41,852,681

G

surfeit 4

CTD Direct Evidence: marker/mechanism

NCBI chr12:4,759,307...4,775,227
Ensembl chr12:4,759,388...4,776,219

G

TATA-box binding protein associated factor 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr12:47,620,400...47,626,369

G

transporter 1, ATP binding cassette subfamily B member

CTD Direct Evidence: marker/mechanism

NCBI chr17:39,252,000...39,260,195

G

TBC1 domain family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:41,160,921...41,221,547
Ensembl chr12:41,161,695...41,222,815

G

TBL1X/Y related 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:12,223,404...12,406,165
Ensembl chr15:12,224,226...12,402,908

G

T-box transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:109,952,100...109,966,328
Ensembl chr11:109,952,054...109,965,065

G

thromboxane A synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163

G

transcription elongation factor A like 7

CTD Direct Evidence: marker/mechanism

NCBI chr X:91,233,827...91,235,963
Ensembl chr X:91,235,036...91,235,338

G

transcobalamin 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:13,489,849...13,511,360
Ensembl chr19:13,490,645...13,511,810

G

t-complex 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:87,377,452...87,388,692
Ensembl chr13:87,377,996...87,388,568

G

telomerase reverse transcriptase

CTD Direct Evidence: marker/mechanism

PMID:19151717 PMID:21743467

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

tet methylcytosine dioxygenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:53,193,824...53,326,813
Ensembl chr 7:53,193,941...53,326,942

G

transforming growth factor alpha

CTD Direct Evidence: therapeutic

NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237

G

transforming growth factor beta 1

CTD Direct Evidence: marker/mechanism

PMID:15159307 PMID:18082198

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

G

transforming growth factor beta receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

G

thrombospondin type 1 domain containing 8

CTD Direct Evidence: marker/mechanism

G

thymocyte nuclear protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:125,308,232...125,313,553

G

TIMP metallopeptidase inhibitor 4

CTD Direct Evidence: marker/mechanism

PMID:16940965 PMID:17013881

NCBI chr22:48,134,133...48,140,870
Ensembl chr22:48,134,637...48,140,600

G

TIR domain containing adaptor protein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:117,417,561...117,419,870

G

tight junction protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 6:3,474,639...3,505,801
Ensembl chr 6:3,481,060...3,505,678

G

toll like receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515

G

toll like receptor 5

CTD Direct Evidence: marker/mechanism

NCBI chr25:6,418,895...6,440,433
Ensembl chr25:6,437,638...6,440,211

G

toll like receptor 6

CTD Direct Evidence: marker/mechanism

NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571

G

transmembrane protein with EGF like and two follistatin like domains 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:77,491,041...77,735,890
Ensembl chr10:77,490,095...77,735,849

G

TATA element modulatory factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:30,048,269...30,078,600
Ensembl chr22:30,045,685...30,078,414

G

tropomodulin 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:41,808,594...41,899,713
Ensembl chr12:41,811,036...41,877,357

G

thymosin beta 4 X-linked

CTD Direct Evidence: marker/mechanism

NCBI chr X:11,454,090...11,456,268

G

TNF receptor superfamily member 10a

CTD Direct Evidence: marker/mechanism

NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673

G

TNF receptor superfamily member 11a

protein:increased expression:prostate gland

NCBI chr18:17,385,251...17,446,442

G

TNF receptor superfamily member 21

CTD Direct Evidence: marker/mechanism

NCBI chr17:24,981,649...25,053,504
Ensembl chr17:24,981,540...25,055,897

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

PMID:16368536 PMID:17636462 PMID:17718901 PMID:21209944

NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860

G

target of myb1 like 1 membrane trafficking protein

CTD Direct Evidence: marker/mechanism

NCBI chr16:38,425,406...38,477,444
Ensembl chr16:38,414,535...38,477,416

G

DNA topoisomerase II alpha

CTD Direct Evidence: marker/mechanism

NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

PMID:16434975 PMID:17202838 PMID:20875869 PMID:21946351 PMID:25735316 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

G

tumor protein p63

CTD Direct Evidence: marker/mechanism
protein:decreased expression:prostate gland
mRNA:decreased expression:prostate gland

PMID:17189982 PMID:17982114 PMID:22581815

RGD:2315433 RGD:2315434

NCBI chr15:83,861,489...84,126,675

G

trophoblast glycoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr13:7,047,658...7,051,390
Ensembl chr13:7,049,415...7,050,680

G

tumor protein D52

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:17875733 PMID:27415467

NCBI chr 8:75,482,413...75,616,018

G

TPD52 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:48,450,068...48,559,488
Ensembl chr13:48,450,058...48,559,504

G

tripeptidyl peptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:58,205,999...58,211,743
Ensembl chr 1:58,206,072...58,210,945

G

tumor protein, translationally-controlled 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:23,428,523...23,432,846
Ensembl chr 3:23,429,044...23,433,108

G

TNF receptor associated factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:18,647,131...18,672,685
Ensembl chr12:18,650,190...18,670,643

G

transient receptor potential cation channel subfamily M member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146

G

thiosulfate sulfurtransferase

CTD Direct Evidence: marker/mechanism

NCBI chr19:19,716,295...19,724,712
Ensembl chr19:19,716,180...19,724,589

G

tetratricopeptide repeat domain 9C

CTD Direct Evidence: marker/mechanism

NCBI chr 1:11,166,185...11,178,935
Ensembl chr 1:11,165,910...11,179,138

G

thioredoxin domain containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr17:64,250,319...64,278,102
Ensembl chr17:64,250,359...64,281,195

G

thioredoxin reductase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:5,803,178...5,868,224
Ensembl chr19:5,813,099...5,866,674

G

thymidylate synthetase

CTD Direct Evidence: marker/mechanism

NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856

G

uridine-cytidine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr25:62,974,515...63,059,436
Ensembl chr25:62,974,257...63,059,414

G

uncoupling protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:65,269,611...65,279,079
Ensembl chr 1:65,269,607...65,278,807

G

uridine monophosphate synthetase

CTD Direct Evidence: marker/mechanism

PMID:15999119 PMID:19082440

NCBI chr22:56,081,897...56,097,164
Ensembl chr22:56,082,103...56,097,105

G

unc-13 homolog D

CTD Direct Evidence: marker/mechanism

NCBI chr16:45,836,659...45,856,805
Ensembl chr16:45,838,175...45,857,201

G

USO1 vesicle transport factor

CTD Direct Evidence: marker/mechanism

NCBI chr 7:24,236,601...24,325,575
Ensembl chr 7:24,236,698...24,325,630

G

ubiquitin specific peptidase 28

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167

NCBI chr 1:105,175,116...105,257,163
Ensembl chr 1:105,175,067...105,257,102

G

ubiquitin specific peptidase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 5:8,470,137...8,540,736
Ensembl chr 5:8,469,230...8,540,770

G

ubiquitously expressed prefoldin like chaperone

CTD Direct Evidence: marker/mechanism

NCBI chr X:44,828,836...44,836,433
Ensembl chr X:44,828,841...44,835,985

G

vav guanine nucleotide exchange factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:25,631,104...26,023,854
Ensembl chr20:25,631,171...26,023,849

G

valosin containing protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:45,545,139...45,560,702
Ensembl chr12:45,545,507...45,563,380

G

vitamin D receptor

CTD Direct Evidence: marker/mechanism

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

PMID:12893367 PMID:16606632 PMID:16908180 PMID:20052738

NCBI chr17:28,377,959...28,394,508

G

vimentin

CTD Direct Evidence: marker/mechanism

PMID:17566973 PMID:24763052

NCBI chr 9:17,183,466...17,191,771
Ensembl chr 9:17,183,388...17,191,829

G

vasoactive intestinal peptide

CTD Direct Evidence: marker/mechanism

NCBI chr13:80,217,602...80,228,320
Ensembl chr13:80,218,572...80,228,278

G

VPS52 subunit of GARP complex

CTD Direct Evidence: marker/mechanism

NCBI chr17:38,805,072...38,824,526
Ensembl chr17:38,805,355...38,825,383

G

WW domain containing adaptor with coiled-coil

CTD Direct Evidence: marker/mechanism

NCBI chr 9:28,131,774...28,222,501
Ensembl chr 9:28,131,769...28,219,134

G

WASP family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:5,805,115...5,934,764
Ensembl chr 3:5,889,263...5,931,662

G

Wnt family member 10B

CTD Direct Evidence: marker/mechanism

NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893

G

Wnt family member 11

disease_progression

mRNA:increased expression:tumor:increased expression in 4/4 cases with Gleason sum score >= 7, also in progression from androgen-dependence to androgen-independence in xenografts

NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509

G

Wnt family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203

G

X-linked inhibitor of apoptosis

severity

G

exportin 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723

G

X-ray repair cross complementing 1

CTD Direct Evidence: marker/mechanism

PMID:16406883 PMID:17196815 PMID:17486273

NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094

G

zinc finger BED-type containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:603,749...618,949
Ensembl chr X:605,953...608,037

G

zinc finger and BTB domain containing 16

CTD Direct Evidence: marker/mechanism

NCBI chr 1:105,446,067...105,648,771
Ensembl chr 1:105,449,994...105,643,344

G

zinc finger and BTB domain containing 20

CTD Direct Evidence: marker/mechanism

NCBI chr22:65,715,470...66,528,195
Ensembl chr22:66,511,237...66,524,064

G

zinc finger and BTB domain containing 7A

CTD Direct Evidence: therapeutic

NCBI chr 6:3,802,171...3,824,552
Ensembl chr 6:3,801,046...3,812,884

G

zinc finger AN1-type containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr12:83,403,552...83,414,572
Ensembl chr12:83,401,111...83,414,591

G

zinc finger homeobox 3

CTD Direct Evidence: marker/mechanism

PMID:16637072 PMID:17013881 PMID:29610475

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

G

ZFP36 ring finger protein like 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:64,019,633...64,022,301
Ensembl chr14:64,019,418...64,026,281

G

Zic family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:78,631,556...78,637,422
Ensembl chr 3:78,631,530...78,636,548

G

zinc finger MYM-type containing 3

CTD Direct Evidence: marker/mechanism

PMID:24763052 PMID:29610475 PMID:29662167

NCBI chr X:61,035,332...61,050,757
Ensembl chr X:61,035,325...61,050,172

G

zinc finger protein 160

CTD Direct Evidence: marker/mechanism

NCBI chr 6:45,806,754...45,844,629

G

zinc finger protein 292

CTD Direct Evidence: marker/mechanism

PMID:29610475 PMID:29662167

NCBI chr13:11,648,871...11,760,029
Ensembl chr13:11,651,537...11,762,656

castration-resistant prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

CTD Direct Evidence: marker/mechanism

PMID:18985049 PMID:24740322 PMID:28500234 PMID:28757136

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

anti-silencing function 1B histone chaperone

CTD Direct Evidence: marker/mechanism

NCBI chr 6:12,760,865...12,773,423

G

cyclin E2

treatment

NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037

G

CD46 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr25:21,650,825...21,693,898
Ensembl chr25:21,655,969...21,693,878

G

centromere protein K

CTD Direct Evidence: marker/mechanism

NCBI chr 4:61,712,006...61,755,082
Ensembl chr 4:61,712,043...61,747,178

G

chromodomain helicase DNA binding protein 1

DNA:mutations: :

NCBI chr23:2,433,694...2,507,334
Ensembl chr23:2,432,461...2,507,704

G

lysine demethylase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr20:109,592,761...109,657,885
Ensembl chr20:109,593,074...109,657,839

G

NUF2 component of NDC80 kinetochore complex

treatment

NCBI chr25:65,462,608...65,493,242
Ensembl chr25:65,462,603...65,493,246

G

signal transducer and activator of transcription 5A

treatment
disease_progression

DNA:CNV: :prostate (human)

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

G

tripartite motif containing 24

CTD Direct Evidence: marker/mechanism

NCBI chr21:107,166,180...107,291,897
Ensembl chr21:107,166,395...107,295,736

G

zinc finger protein 217

CTD Direct Evidence: marker/mechanism

NCBI chr 2:10,427,584...10,455,308
Ensembl chr 2:10,439,082...10,450,670

G

zinc finger protein 367

CTD Direct Evidence: marker/mechanism

NCBI chr12:106,712,962...106,743,351
Ensembl chr12:106,713,310...106,741,040

Familial Prostate Cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adhesion G protein-coupled receptor G1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:43,559,792...43,595,906
Ensembl chr 5:43,570,189...43,596,087

G

androgen receptor

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8530589 PMID:10589774 PMID:11103816 PMID:28492532

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

Rho GTPase activating protein 6

CTD Direct Evidence: marker/mechanism

G

alpha tubulin acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:41,807,405...41,830,670
Ensembl chr17:41,807,291...41,830,000

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:15928302 PMID:16199547 PMID:16941484 PMID:17124347 PMID:17910737 More...

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

beta-1,3-glucuronyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:125,449,162...125,490,208
Ensembl chr 1:125,448,500...125,490,192

G

brain enriched myelin associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,972,244...10,098,126
Ensembl chr 2:9,972,433...10,096,747

G

BCL2 apoptosis regulator

CTD Direct Evidence: marker/mechanism

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

G

BCL2 like 11

CTD Direct Evidence: marker/mechanism

NCBI chr14:14,178,159...14,205,337

G

bridge-like lipid transfer protein family member 3A

CTD Direct Evidence: marker/mechanism

NCBI chr17:37,241,841...37,322,220
Ensembl chr17:37,246,908...37,321,337

G

BRCA1 DNA repair associated

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:17319787 PMID:18489799 PMID:20104584 PMID:21203900 PMID:25525159 More...

NCBI chr16:63,162,827...63,243,928

G

caspase 8

CTD Direct Evidence: marker/mechanism

NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829

G

cell division cycle associated 7

CTD Direct Evidence: marker/mechanism

NCBI chr10:58,847,319...58,859,843
Ensembl chr10:58,848,781...58,859,845

G

cyclin dependent kinase inhibitor 1B

CTD Direct Evidence: marker/mechanism

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

G

chromodomain helicase DNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,274,634...7,300,831
Ensembl chr16:7,276,850...7,300,832

G

checkpoint kinase 2

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:21876083 PMID:24713400 PMID:25741868 PMID:26467025 PMID:27083775 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

collagen type XXIII alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr23:79,932,340...80,279,808

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182

G

DENN domain containing 4B

CTD Direct Evidence: marker/mechanism

NCBI chr20:9,865,833...9,882,259
Ensembl chr20:9,868,106...9,881,465

G

DNA methyltransferase 3 beta

CTD Direct Evidence: marker/mechanism

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

G

dedicator of cytokinesis 2

CTD Direct Evidence: marker/mechanism

NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056

G

EMSY transcriptional repressor, BRCA2 interacting

CTD Direct Evidence: marker/mechanism

NCBI chr 1:67,657,747...67,762,157
Ensembl chr 1:67,657,753...67,760,610

G

fibrosin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:127,840,826...127,936,739

G

HAUS augmin like complex subunit 6

CTD Direct Evidence: marker/mechanism

G

homeobox B13

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

inner centromere protein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:11,695,803...11,725,633
Ensembl chr 1:11,692,559...11,720,940

G

integrin subunit beta 8

CTD Direct Evidence: marker/mechanism

NCBI chr21:37,811,811...37,896,539
Ensembl chr21:37,817,572...37,895,560

G

lysine demethylase 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:7,004,109...7,152,072
Ensembl chr 1:7,003,784...7,082,720

G

kinetochore scaffold 1

CTD Direct Evidence: marker/mechanism

NCBI chr26:42,342,741...42,409,466

G

La ribonucleoprotein 4B

CTD Direct Evidence: marker/mechanism

NCBI chr 9:778,786...898,263

G

long intergenic non-protein coding RNA 3103

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,646,904...26,648,574

G

cadherin-1

CTD Direct Evidence: marker/mechanism

PMID:14961571 PMID:16189707

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

cytochrome P450 3A8

no_association

NCBI chr28:13,297,566...13,330,023

G

mitotic arrest deficient 1 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

mitogen-activated protein kinase kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

G

methyl-CpG binding domain protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:26,714,610...26,785,028

G

muscleblind like splicing regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:38,208,694...38,427,867
Ensembl chr15:38,208,038...38,375,273

G

MDS1 and EVI1 complex locus

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,726,423...20,320,832
Ensembl chr15:20,256,384...20,320,834

G

major histocompatibility complex, class II, DO alpha

CTD Direct Evidence: marker/mechanism

NCBI chr17:39,084,785...39,090,477
Ensembl chr17:39,085,080...39,090,474

G

matrix metallopeptidase 14

CTD Direct Evidence: marker/mechanism

NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679

G

MOB kinase activator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:1,267,041...1,338,940
Ensembl chr 1:1,266,952...1,338,895

G

mutS homolog 6

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:18269114 PMID:24362816 PMID:25741868 PMID:28492532

NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174

G

myosin IXB

CTD Direct Evidence: marker/mechanism

NCBI chr 6:15,571,276...15,707,571
Ensembl chr 6:15,596,583...15,707,567

G

paired box 9

CTD Direct Evidence: marker/mechanism

NCBI chr24:13,454,839...13,470,564
Ensembl chr24:13,455,589...13,473,505

G

PBX/knotted 1 homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:116,332,851...116,604,758
Ensembl chr 1:116,523,593...116,605,161

G

POU class 2 homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,292,252...36,382,354
Ensembl chr 6:36,295,275...36,336,013

G

PPFIA binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:57,182,518...57,326,875
Ensembl chr 1:57,182,327...57,289,827

G

Ras association domain family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:60,289,751...60,374,220
Ensembl chr11:60,289,680...60,375,600

G

regulatory factor X7

CTD Direct Evidence: marker/mechanism

NCBI chr26:27,248,814...27,399,385

G

ribonuclease L

CTD Direct Evidence: marker/mechanism

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

ring finger protein 43

CTD Direct Evidence: marker/mechanism

NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107

G

renalase, FAD dependent amine oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr 9:81,725,115...82,029,361

G

succinyl-CoA:glutarate-CoA transferase

CTD Direct Evidence: marker/mechanism

NCBI chr21:17,621,886...18,511,591
Ensembl chr21:18,151,535...18,511,310

G

transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr18:24,116,595...24,483,037
Ensembl chr18:24,116,547...24,478,228

G

transcription factor 7 like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:105,828,834...106,047,810

G

torsin family 1 member A

CTD Direct Evidence: marker/mechanism

NCBI chr12:8,312,652...8,323,932
Ensembl chr12:8,312,650...8,322,907

G

teashirt zinc finger homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:4,622,407...4,702,267
Ensembl chr18:4,623,731...4,626,925

G

tetratricopeptide repeat domain 28

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,883,566...11,559,332
Ensembl chr19:10,887,702...11,334,237

prostate adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

susceptibility

DNA:SNPs, haplotypes:5' utr, introns, exon:multiple

NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391

G

adiponectin receptor 1

susceptibility

DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human)

NCBI chr25:26,445,993...26,462,346
Ensembl chr25:26,453,242...26,462,549

G

AKT serine/threonine kinase 1

treatment

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

G

AKT serine/threonine kinase 2

treatment

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

AKT serine/threonine kinase 3

treatment

NCBI chr25:80,509,701...80,878,792
Ensembl chr25:80,515,168...80,816,018

G

androgen receptor

treatment

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

bridging integrator 1

NCBI chr10:3,112,605...3,173,522
Ensembl chr10:3,113,868...3,173,620

G

baculoviral IAP repeat containing 6

ameliorates

mRNA:increased expression:prostate gland (human)

NCBI chr14:74,879,597...75,138,462
Ensembl chr14:74,878,700...75,138,441

G

baculoviral IAP repeat containing 7

exacerbates

mRNALincreased expression:prostate gland (human)

NCBI chr 2:965,811...970,983

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:2493360 PMID:12068308 PMID:12198537 PMID:12460918 PMID:12460919 More...

NCBI chr21:109,495,525...109,690,261

G

calcium/calmodulin dependent protein kinase II inhibitor 1

treatment

NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256

G

cyclin B1

severity

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

G

cyclin E2

NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037

G

CD9 molecule

disease_progression

DNA, mRNA:deletion, point mutation, decreased expression:prostate gland

NCBI chr11:6,236,449...6,275,904
Ensembl chr11:6,236,494...6,275,909

G

chromodomain helicase DNA binding protein 4

mRNA:decreased expression:prostate gland (human)

NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351

G

component of inhibitor of nuclear factor kappa B kinase complex

treatment

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

G

clusterin

treatment

NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789

G

CCR4-NOT transcription complex subunit 9

ClinVar Annotator: match by term: Prostate adenocarcinoma

NCBI chr10:104,473,215...104,502,321
Ensembl chr10:104,473,216...104,503,007

G

cAMP responsive element binding protein 3 like 4

PMID:11830526 PMID:17270658

RGD:13504714 RGD:13504715

NCBI chr20:9,839,137...9,848,413
Ensembl chr20:9,838,085...9,845,287

G

catenin beta 1

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More...

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

DNA methyltransferase 1

mRNA,protein:increased expression:prostate gland:

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

DNA methyltransferase 3 alpha

mRNA:increased expression:prostate gland:

NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819

G

DNA methyltransferase 3 beta

mRNA,protein:increased expression:prostate gland:

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:23220880 PMID:26619011

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

G

fibroblast growth factor 2

disease_progression

NCBI chr 7:70,089,394...70,157,423

G

fibroblast growth factor receptor 1

PMID:18068632 PMID:23576558

RGD:13504748 RGD:2298702

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

growth factor receptor bound protein 2

NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975

G

insulin like growth factor 1 receptor

treatment
disease_progression

PMID:8692980 PMID:25442907 PMID:25862373 PMID:26452103

RGD:13504753 RGD:13504767 RGD:13504768 RGD:13504771

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

inhibitor of nuclear factor kappa B kinase subunit beta

treatment

NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381

G

integrin linked kinase

disease_progression

protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004)

NCBI chr 1:58,214,630...58,221,770
Ensembl chr 1:58,213,310...58,221,217

G

insulin receptor

treatment

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

protein:increased expression, increased activation:significantly higher levels in invading vs organ-confined specimens (P<0.001)

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

G

kinase insert domain receptor

protein:increased expression:tumor:relative to benign prostatic hypertrophy (BPH) tissue
protein:increased expression:prostate gland

PMID:17491265 PMID:20808233

RGD:2291925 RGD:5684541

NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633

G

mitogen-activated protein kinase kinase 1

disease_progression

metastasis; inhibition reduced invasiveness of prostate tumor cells
ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:12688676 PMID:23444215 PMID:25157968 PMID:26619011

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

G

mitogen-activated protein kinase 1

treatment

PMID:22139534 PMID:28492138

RGD:13504818 RGD:13504820

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

G

mediator complex subunit 12

ClinVar Annotator: match by term: Prostate adenocarcinoma

NCBI chr X:60,915,796...60,939,220
Ensembl chr X:60,915,703...60,937,677

G

MYC proto-oncogene, bHLH transcription factor

human gene in mouse model

PMID:14522256 PMID:20195545

RGD:7207413 RGD:7207781

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

nuclear receptor coactivator 2

ameliorates

human cells in mouse model

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

G

NFKB inhibitor alpha

severity

protein:increased serine phosphorylation

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

peptidylglycine alpha-amidating monooxygenase

mRNA:increased expression:prostate gland (human)

NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751

G

platelet derived growth factor subunit A

protein:increased expression:prostate

NCBI chr28:21,044,549...21,068,411
Ensembl chr28:21,047,219...21,069,827

G

platelet derived growth factor receptor alpha

protein:increased expression:prostate

NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422

G

3-phosphoinositide dependent protein kinase 1

treatment

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

G

protein phosphatase 2 scaffold subunit Aalpha

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More...

NCBI chr 6:44,990,402...45,026,210
Ensembl chr 6:44,990,367...45,026,227

G

protein kinase C theta

mRNA:increased expression:prostate

NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More...

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020

G

RELA proto-oncogene, NF-kB subunit

disease_progression

protein:increased expression:prostate gland

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

G

SMAD family member 4

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:6604412 PMID:12116240 PMID:15031030 PMID:26619011

NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478

G

speckle type BTB/POZ protein

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:23265383 PMID:26619011

NCBI chr16:69,990,554...70,073,241

G

signal transducer and activator of transcription 1

disease_progression

protein:increased activity:prostate

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

G

telomerase reverse transcriptase

treatment

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

transmembrane serine protease 2

disease_progression

protein:increased expression, altered localization:prostate gland

NCBI chr 2:85,372,881...85,413,717
Ensembl chr 2:85,372,117...85,412,926

G

tumor protein p53

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1591732 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

G

exportin 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723

prostate cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 4 (PEL blood group)

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579

G

ATP binding cassette subfamily E member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:91,673,359...91,704,774

G

ATP binding cassette subfamily F member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:5,232,161...5,240,012
Ensembl chr15:5,227,836...5,239,958

G

ATP binding cassette subfamily G member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:110,522,773...110,537,747
Ensembl chr 1:110,524,900...110,537,735

G

ankyrin repeat and BTB domain containing 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:102,535,469...102,882,227
Ensembl chr11:102,800,591...102,882,388

G

acid phosphatase 3

disease_progression

PSA/PAP (prostatic acid phosphatase) ratio - a valuable prognostic indicator in men with Stage IV prostate cancer
OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

PMID:16024648 PMID:17991541

RGD:2301054 RGD:2301055

NCBI chr15:57,887,528...57,934,851
Ensembl chr15:57,887,365...57,934,707

G

acrosomal vesicle protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:116,812,667...116,821,625
Ensembl chr 1:116,812,726...116,821,073

G

acyl-CoA synthetase long chain family member 3

disease_progression
treatment

NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042

G

ADAM metallopeptidase with thrombospondin type 1 motif 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:20,793,392...21,068,712
Ensembl chr 7:20,793,399...21,048,515

G

adenosine deaminase tRNA specific 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:61,083,029...61,108,751
Ensembl chr 5:61,082,819...61,108,330

G

ADRM1 26S proteasome ubiquitin receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:1,930,281...1,936,323
Ensembl chr 2:1,925,382...1,936,393

G

adenylosuccinate lyase

severity

protein:increased activity:tumor (human)

NCBI chr19:22,920,971...22,940,468

G

alpha fetoprotein

protein:increased expression:serum

NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

protein:increased expression:prostate

NCBI chr11:53,638,722...53,655,826
Ensembl chr11:53,640,079...53,651,913

G

AGBL carboxypeptidase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:82,893,087...84,293,578

G

advanced glycosylation end-product specific receptor

mRNA:increased expression:prostate gland (human)

NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127

G

1-acylglycerol-3-phosphate O-acyltransferase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:1,511,063...1,525,146
Ensembl chr12:1,511,124...1,525,440

G

aryl-hydrocarbon receptor repressor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:220,523...329,973
Ensembl chr 4:243,026...326,722

G

apoptosis inducing factor mitochondria associated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:105,383,408...105,419,146
Ensembl chr X:105,382,693...105,419,095

G

A-kinase anchoring protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:36,275,287...36,313,612
Ensembl chr16:36,275,209...36,306,012

G

AKT serine/threonine kinase 1

severity

DNA:SNPs:5' utr, intron: (rs1130214, rs2494738) (human)

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

G

AKT serine/threonine kinase 2

DNA:SNP: :rs7254617 (human)

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

AKT serine/threonine kinase 3

severity

DNA:SNP: :rs2125230 (human)

NCBI chr25:80,509,701...80,878,792
Ensembl chr25:80,515,168...80,816,018

G

aldehyde dehydrogenase 5 family member A1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:47,712,785...47,746,198
Ensembl chr17:47,709,888...47,745,830

G

aldehyde dehydrogenase 9 family member A1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:63,184,220...63,223,865

G

arachidonate 12-lipoxygenase, 12S type

disease_progression

mRNA:increased expression:prostate gland

NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738

G

adenosylmethionine decarboxylase 1

protein:increased expression:prostate

NCBI chr13:62,977,659...62,999,150

G

angiogenin

PMID:11948474 PMID:19276260

RGD:2325697 RGD:2325707

NCBI chr29:21,215,985...21,226,927

G

ankyrin repeat domain 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:68,055,330...68,189,543
Ensembl chr18:68,121,005...68,187,751

G

anoctamin 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:235,246...253,391
Ensembl chr 1:235,702...249,990

G

annexin A7

protein:decreased expression:prostate gland

NCBI chr 9:57,863,482...57,900,972
Ensembl chr 9:57,863,546...57,900,324

G

adaptor related protein complex 3 subunit beta 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 4:72,225,658...72,524,971
Ensembl chr 4:72,225,599...72,524,933

G

APC regulator of WNT signaling pathway

disease_progression

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067

G

androgen receptor

no_association
susceptibility
treatment

african-american men
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

RGD
OMIM
ClinVar

PMID:1307250 PMID:1631125 PMID:1779964 PMID:2594783 PMID:7671849 More...

RGD:10043311 RGD:1578686

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:44,280,010...44,308,046
Ensembl chr23:44,279,727...44,306,272

G

Rho GTPase activating protein 20

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:101,920,074...102,047,171
Ensembl chr 1:101,921,839...102,046,751

G

Rho guanine nucleotide exchange factor 15

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:7,674,190...7,687,129
Ensembl chr16:7,674,577...7,687,834

G

Rho guanine nucleotide exchange factor 25

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,518,295...53,525,428
Ensembl chr11:53,518,397...53,525,068

G

Rho guanine nucleotide exchange factor 40

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:21,543,572...21,563,229
Ensembl chr29:21,546,064...21,562,558

G

armadillo repeat containing 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:36,368,789...36,392,119
Ensembl chr17:36,368,832...36,388,749

G

cAMP regulated phosphoprotein 21

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:80,048,078...80,204,843
Ensembl chr15:80,089,657...80,204,314

G

acid sensing ion channel subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:26,547,878...27,674,909

G

aspartic peptidase retroviral like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:37,019,454...37,051,341
Ensembl chr14:37,158,086...37,159,117
Ensembl chr14:37,158,086...37,159,117

G

activating transcription factor 3

disease_progression
treatment

PMID:26522727 PMID:26944919

RGD:13506816 RGD:13506817

NCBI chr25:16,910,312...16,922,598

G

autophagy related 13

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:18,651,872...18,712,395
Ensembl chr 1:18,652,998...18,712,482

G

atlastin GTPase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:10,569,052...10,611,518
Ensembl chr 1:10,569,235...10,611,323

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23807571 PMID:25614872 PMID:25741868 PMID:28492532

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

ATPase Na+/K+ transporting subunit alpha 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054

G

ATPase plasma membrane Ca2+ transporting 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:25,602,857...25,716,385
Ensembl chr25:25,602,715...25,661,553

G

ATPase H+ transporting V0 subunit a1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:63,754,523...63,818,537
Ensembl chr16:63,753,521...63,816,551

G

alpha-2-glycoprotein 1, zinc-binding

protein:increased expression:serum

NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363

G

beta-1,3-galactosyltransferase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:52,792,505...53,368,536
Ensembl chr10:53,366,522...53,367,499

G

BRISC and BRCA1 A complex member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:79,277,238...79,732,996
Ensembl chr14:79,289,043...79,732,891

G

BAG cochaperone 1

DNA, protein:amplification, increased expression:prostate gland

NCBI chr12:47,006,177...47,016,177

G

BCL2 associated X, apoptosis regulator

PMID:17575222 PMID:18444130

RGD:1643354 RGD:2292907

NCBI chr 6:42,186,028...42,193,105

G

BCL2 apoptosis regulator

disease_progression

PMID:16984224 PMID:17850375 PMID:18084610

RGD:2292512 RGD:2293015 RGD:2293017

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

G

BEN domain containing 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:84,054,527...84,103,998
Ensembl chr20:84,054,586...84,104,279

G

bone gamma-carboxyglutamate protein

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

G

BICRA like chromatin remodeling complex associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:29,283,287...29,402,201
Ensembl chr17:29,283,150...29,331,259

G

BCL2 interacting killer

NCBI chr19:25,632,837...25,658,951
Ensembl chr19:25,652,945...25,658,541

G

baculoviral IAP repeat containing 5

severity

mRNA:increased expression:prostate gland

PMID:17804712 PMID:18336887

RGD:2293091 RGD:2293100

NCBI chr16:70,226,824...70,237,000

G

bridge-like lipid transfer protein family member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:22,383,058...22,414,910
Ensembl chr16:22,383,677...22,412,701

G

bone morphogenetic protein 2

disease_progression
susceptibility

DNA:amplification:prostate gland

PMID:15042598 PMID:17656261

RGD:2289030 RGD:2299981

NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901

G

bone morphogenetic protein 6

protein:increased expression:prostate

NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382

G

bone morphogenetic protein 7

susceptibility

protein:decreased expression:prostate gland
DNA:amplification:prostate gland

PMID:15861517 PMID:17656261

RGD:2289030 RGD:2289031

NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944

G

BCL2 interacting protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:35,792,013...35,807,059
Ensembl chr17:35,792,115...35,805,471

G

BRCA1 DNA repair associated

no_association
severity

ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:deletions: :185_186del,1294_1333del,3875_3878del

PMID:10398279 PMID:12491487 PMID:15235020 PMID:15447980 PMID:16267036 More...

RGD:2289042 RGD:734657

NCBI chr16:63,162,827...63,243,928

G

BRCA2 DNA repair associated

disease_progression

DNA:mutation
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

RGD
OMIM
ClinVar

PMID:1 PMID:251866 PMID:278235 PMID:2200631 PMID:8524414 More...

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

G

BRF2 RNA polymerase III transcription initiation factor subunit

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:35,879,762...35,885,572
Ensembl chr 8:35,880,373...35,885,485

G

BTB domain containing 16

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:115,005,070...115,073,976
Ensembl chr 9:115,010,795...115,073,899

G

C2 calcium dependent domain containing 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:87,133,453...87,303,521
Ensembl chr10:87,133,461...87,302,735

G

complement C3a receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:8,128,192...8,135,517
Ensembl chr11:8,128,620...8,130,062

G

complement C5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:18,525,855...18,624,048
Ensembl chr12:18,525,880...18,623,636

G

calcineurin binding protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:7,127,370...7,289,054
Ensembl chr19:7,127,401...7,289,050

G

calcium voltage-gated channel subunit alpha1 D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101

G

cell adhesion molecule 1

DNA:hypermethylation:promoter

NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637

G

cell adhesion molecule 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:4,746,751...4,777,321
Ensembl chr20:4,747,800...4,777,298

G

calcium dependent secretion activator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:23,471,616...23,948,694

G

calcium/calmodulin dependent protein kinase II inhibitor 1

disease_progression

mRNA, protein:decreased expression:prostate gland

PMID:25003983 PMID:31762801

RGD:18337271 RGD:18337280

NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256

G

cullin associated and neddylation dissociated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:62,923,198...62,968,789
Ensembl chr11:62,922,885...62,966,994

G

calpain 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:99,052,100...99,077,508
Ensembl chr X:99,051,989...99,077,302

G

calcium/calmodulin dependent serine protein kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:38,704,623...39,121,309

G

caspase 1

protein:decreased expression:prostate gland

NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849

G

caspase 3

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

G

calcium sensing receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756

G

caveolin 1

disease_progression

protein:increased expression:serum
DNA:hypermethylation:promoter

PMID:11170154 PMID:14506154 PMID:15948133

RGD:2289104 RGD:2289109 RGD:2289112

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

G

chromobox 1

protein:increased expression:prostate:

NCBI chr16:68,471,298...68,508,180

G

chromobox 3

protein:increased expression:prostate:

NCBI chr21:32,154,707...32,166,843
Ensembl chr21:32,155,839...32,166,114

G

chromobox 5

protein:increased expression:prostate:

NCBI chr11:50,350,440...50,396,595
Ensembl chr11:50,353,638...50,396,608

G

chromobox 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309

G

chibby 1, beta catenin antagonist

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,318,124...21,335,973
Ensembl chr19:21,318,164...21,338,920

G

coiled-coil domain containing 171

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:63,594,745...64,044,086
Ensembl chr12:63,753,934...64,042,872

G

cyclin A1

disease_progression

human gene, mouse model

NCBI chr 3:14,979,775...14,992,609
Ensembl chr 3:14,982,392...14,993,562

G

cyclin B1

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

G

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

G

cyclin D2

disease_progression

DNA, mRNA:hyperymethylation, decreased expression:promoter, prostate gland

PMID:16322291 PMID:17016690

RGD:151665170 RGD:2289151

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

G

cyclin D3

disease_progression

NCBI chr17:30,107,236...30,228,449
Ensembl chr17:30,221,598...30,227,452

G

CD2 molecule

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:16,954,925...16,970,066
Ensembl chr20:16,953,811...16,970,044

G

CD244 molecule

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:3,103,226...3,138,322

G

CD2 associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:24,664,245...24,815,786
Ensembl chr17:24,663,872...24,815,829

G

CD44 molecule (IN blood group)

disease_progression

DNA:hypermethylation:prostate gland

NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416

G

CD55 molecule (Cromer blood group)

PMID:16533428 PMID:18288643

RGD:2326167 RGD:2326168

NCBI chr25:22,055,138...22,092,472
Ensembl chr25:22,073,629...22,092,173

G

CD82 molecule

disease_progression

protein:decreased expression:prostate gland

NCBI chr 1:20,736,216...20,793,943
Ensembl chr 1:20,735,287...20,763,160

G

cell division cycle 25A

NCBI chr22:9,534,114...9,564,927
Ensembl chr22:9,534,053...9,564,741

G

cell division cycle 25B

protein:increased expression:prostate gland

NCBI chr 2:34,482,709...34,493,737
Ensembl chr 2:34,483,771...34,494,071

G

cell division cycle 25C

mRNA, protein:alternative form, increased expression, increased activity:prostate gland

PMID:12896904 PMID:16000564 PMID:16140946 PMID:17460776

RGD:2756028 RGD:2774210 RGD:2776427 RGD:4105453

NCBI chr23:40,960,154...41,013,016
Ensembl chr23:40,960,572...41,006,984

G

cadherin 13

disease_progression

DNA:hypermethylation:promoter

NCBI chr 5:68,048,655...69,213,102
Ensembl chr 5:68,451,894...69,211,534

G

cadherin 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 5:58,717,600...58,775,033
Ensembl chr 5:58,717,597...58,775,339

G

cyclin dependent kinase 13

mRNA,protein:increased expression:prostate:

NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525

G

cyclin dependent kinase 2

NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907

G

cyclin dependent kinase 4

NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861

G

cyclin dependent kinase inhibitor 1A

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

G

CDKN2A interacting protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:129,429,535...129,433,687
Ensembl chr 7:129,429,533...129,435,285

G

ceramide synthase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:18,883,532...19,016,790
Ensembl chr29:18,929,866...18,974,662

G

cilia and flagella associated protein 43

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:97,179,767...97,283,267
Ensembl chr 9:97,179,647...97,283,225

G

cilia and flagella associated protein 65

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:104,902,365...104,946,934
Ensembl chr10:104,902,401...104,944,401

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:42,038,751...42,041,836
Ensembl chr26:42,038,528...42,041,760

G

chromatin assembly factor 1 subunit B

disease_progression

protein:increased expression:prostate:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19309489 PMID:23265383

NCBI chr 2:80,379,637...80,409,626
Ensembl chr 2:80,380,425...80,409,687

G

chromodomain helicase DNA binding protein 1

DNA:deletions: :

NCBI chr23:2,433,694...2,507,334
Ensembl chr23:2,432,461...2,507,704

G

chromodomain helicase DNA binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:11,436,170...11,579,468
Ensembl chr29:11,450,799...11,579,594

G

checkpoint kinase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:116,768,141...116,809,557
Ensembl chr 1:116,767,944...116,801,371

G

checkpoint kinase 2

susceptibility

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to
DNA:mutations: :multiple

OMIM
ClinVar
RGD

PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

chromogranin A

susceptibility

DNA:missense mutation:cds:p.E264D (human)

NCBI chr24:70,663,040...70,675,827
Ensembl chr24:70,663,298...70,677,116

G

chromogranin B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:32,210,079...32,224,123
Ensembl chr 2:32,209,433...32,224,204

G

cysteine rich hydrophobic domain 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:63,124,857...63,244,752
Ensembl chr X:63,124,918...63,241,072

G

component of inhibitor of nuclear factor kappa B kinase complex

protein:increased serine phosphorylation:prostate gland

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

G

cytoskeleton associated protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:18,504,588...18,584,635
Ensembl chr 1:18,484,372...18,586,623

G

CLPTM1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898

G

ciliary neurotrophic factor receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:46,017,992...46,068,187
Ensembl chr12:46,030,203...46,069,944

G

component of oligomeric golgi complex 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:48,426,303...48,441,274
Ensembl chr16:48,423,212...48,441,227

G

collagen type I alpha 1 chain

ClinVar Annotator: match by term: Prostate cancer

PMID:17211858 PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

G

collagen type XXIV alpha 1 chain

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:47,260,635...47,650,408
Ensembl chr20:47,261,261...47,649,269

G

collagen type V alpha 1 chain

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:3,301,643...3,507,300
Ensembl chr12:3,301,175...3,459,607

G

catechol-O-methyltransferase

no_association
disease_progression
susceptibility

DNA:polymorphism: :p.V158M
DNA:polymorphism:cds

PMID:16126332 PMID:16492910 PMID:17507624

RGD:2289718 RGD:2289719 RGD:2289720

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

G

COP9 signalosome subunit 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:12,986,194...12,989,189
Ensembl chr28:12,986,346...12,989,174

G

corin, serine peptidase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:2,407,451...2,662,855
Ensembl chr27:2,408,219...2,662,279

G

carboxypeptidase A6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,281,059...63,590,016
Ensembl chr 8:63,281,180...63,374,824

G

cleavage and polyadenylation specific factor 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:12,417,452...12,445,984
Ensembl chr 1:12,417,490...12,446,527

G

CREB regulated transcription coactivator 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:9,223,410...9,341,576
Ensembl chr29:9,223,409...9,341,514

G

cone-rod homeobox

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:41,125,912...41,133,478
Ensembl chr 6:41,126,125...41,132,951

G

CUB and Sushi multiple domains 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:98,708,384...99,358,093
Ensembl chr20:98,936,373...99,352,601

G

catenin alpha 1

disease_progression

protein:decreased expression:prostate gland

PMID:16334164 PMID:17639504

RGD:2289791 RGD:2289793

NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190

G

catenin beta 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:9927029 PMID:23265383 PMID:25157968 PMID:26619011

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

cathepsin E

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:23,318,421...23,333,885
Ensembl chr25:23,319,248...23,332,980

G

cortactin binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:86,376,005...86,539,662
Ensembl chr21:86,376,011...86,527,223

G

C-X-C motif chemokine ligand 12

ameliorates

human cells in mouse model

NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494

G

C-X-C motif chemokine receptor 4

ameliorates

human cells in mouse model

NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309

G

cytochrome P450 family 17 subfamily A member 1

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

G

cytochrome P450 family 1 subfamily A member 1

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

G

cysteinyl leukotriene receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

G

DAB2 interacting protein

treatment

human cells in mouse model

NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890

G

death domain associated protein

disease_progression

NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071

G

dachsous cadherin-related 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:100,770,541...101,036,985

G

DExD-box helicase 50

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:62,378,977...62,424,108
Ensembl chr 9:62,377,491...62,424,006

G

DExD/H-box helicase 60

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:114,474,678...114,578,749
Ensembl chr 7:114,474,680...114,578,563

G

DExD/H-box 60 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:114,611,177...114,727,737
Ensembl chr 7:114,610,288...114,727,734

G

DEAF1 transcription factor

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 1:487,497...510,440

G

diacylglycerol O-acyltransferase 2 like 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:60,018,508...60,048,540
Ensembl chr X:60,041,748...60,047,814

G

DiGeorge syndrome critical region gene 6 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:2,436,534...2,441,930

G

dihydrodiol dehydrogenase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,170,856...42,180,973
Ensembl chr 6:42,170,873...42,181,015

G

DExH-box helicase 29

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:51,491,356...51,543,889
Ensembl chr 4:51,491,598...51,543,774

G

DIS3 like exosome 3'-5' exoribonuclease

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:17,217,316...17,258,356
Ensembl chr26:17,216,558...17,257,942

G

dihydrolipoamide S-acetyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:103,379,165...103,419,585
Ensembl chr 1:103,380,426...103,420,386

G

delta like canonical Notch ligand 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:97,928,480...97,936,594
Ensembl chr13:97,928,634...97,936,589

G

dynein axonemal heavy chain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:19,068,468...19,274,958
Ensembl chr 5:19,068,515...19,279,417

G

dynein axonemal heavy chain 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:33,110,149...33,427,553
Ensembl chr17:33,110,289...33,419,519

G

dynein axonemal heavy chain 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:10,947,254...11,316,414
Ensembl chr16:10,948,014...11,317,291

G

DnaJ heat shock protein family (Hsp40) member C3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25466870 PMID:28940199

NCBI chr 3:74,474,643...74,582,942
Ensembl chr 3:74,474,548...74,579,048

G

DnaJ heat shock protein family (Hsp40) member C6

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:22563501 PMID:23211418 PMID:26528954 PMID:28492532

NCBI chr20:67,661,187...67,824,822
Ensembl chr20:67,660,680...67,809,086

G

DNA methyltransferase 1

disease_progression

protein:increased expression:nucleus:

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

dedicator of cytokinesis 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056

G

dedicator of cytokinesis 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:23,310,524...23,540,174
Ensembl chr 8:23,310,673...23,540,478

G

diphthamide biosynthesis 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:633,517...651,892

G

developmental pluripotency associated 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:71,435,945...71,446,490
Ensembl chr22:71,435,925...71,446,110

G

dihydropyrimidine dehydrogenase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679

G

DS cell adhesion molecule like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:108,801,895...109,167,011
Ensembl chr 1:108,802,452...108,906,272

G

dual specificity phosphatase 1

disease_progression

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

G

dymeclin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:31,513,665...31,902,064
Ensembl chr18:31,513,735...31,901,811

G

E2F transcription factor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326

G

E2F transcription factor 3

disease_progression

PMID:15184867 PMID:17701752 PMID:25017995

RGD:13504717 RGD:13504729 RGD:13504730

NCBI chr17:51,714,052...51,805,827

G

E2F transcription factor 5

mRNA,protein:increased expression:prostate:

NCBI chr 8:80,542,390...80,587,888
Ensembl chr 8:80,542,580...80,587,226

G

ELL associated factor 2

protein:decreased expression:prostate gland

NCBI chr22:58,966,640...59,025,158
Ensembl chr22:58,974,409...59,025,143

G

eukaryotic translation elongation factor 2

protein:increased expression:prostate (human)

NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826

G

EF-hand calcium binding domain 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:26,023,566...26,327,309
Ensembl chr19:26,023,643...26,295,493

G

epidermal growth factor receptor

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

G

eukaryotic translation initiation factor 3 subunit H

disease_progression

DNA:amplification
mRNA:increased expression:prostate gland

PMID:10362802 PMID:11733359

RGD:2289901 RGD:2289902

NCBI chr 8:111,283,184...111,390,835

G

eukaryotic translation initiation factor 4 gamma 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:111,381,420...111,747,248
Ensembl chr20:111,469,837...111,747,416

G

elongin A2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:33,924,612...33,927,003

G

elastin microfibril interfacer 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:80,531,973...80,539,820

G

endoglin

severity

protein:increased expression:tumor, vasculature (human)

NCBI chr12:10,274,705...10,315,715
Ensembl chr12:10,275,064...10,315,040

G

enolase 2

NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304

G

ecto-NOX disulfide-thiol exchanger 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:21,339,684...21,909,377
Ensembl chr 3:21,339,690...21,545,310

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:71,693,148...71,701,517
Ensembl chr16:71,693,851...71,699,926

G

ectonucleoside triphosphate diphosphohydrolase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:1,881,640...1,923,708
Ensembl chr22:1,882,978...1,923,837

G

endosomal transmembrane epsin interactor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:80,421,600...80,485,566
Ensembl chr12:80,421,683...80,484,918

G

E1A binding protein p300

disease_progression

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

G

EPH receptor B1

susceptibility

DNA:SNPs,haplptype:multiple

NCBI chr15:55,144,178...55,592,252
Ensembl chr15:55,143,630...55,589,862

G

epithelial stromal interaction 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:20,955,649...21,128,997
Ensembl chr 3:21,022,117...21,128,503

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

G

erb-b2 receptor tyrosine kinase 3

disease_progression

protein:altered localization:nucleus
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:17532856 PMID:23265383

NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028

G

erb-b2 receptor tyrosine kinase 4

protein:increased expression:prostate gland

NCBI chr10:97,099,090...98,281,697

G

erbb2 interacting protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:62,123,012...62,267,832
Ensembl chr 4:62,182,705...62,268,617

G

ERCC excision repair 2, TFIIH core complex helicase subunit

susceptibility

DNA:missense mutation:cds:p.D312N (human)
DNA:polymorphism:exon:p.R156R(human)

PMID:17695467 PMID:24649009

RGD:5688739 RGD:8657136

NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073

G

estrogen receptor 1

susceptibility
severity
disease_progression

DNA:repeat
DNA:hypermethylation:promoter
mRNA:increased expression:prostate gland

PMID:17908481 PMID:17922863 PMID:18006911

RGD:2290020 RGD:2290022 RGD:2290023

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G

estrogen receptor 2

susceptibility

DNA:snps, haplotype:multiple (human)

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G

exocyst complex component 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:71,463,836...71,668,429
Ensembl chr17:71,473,962...71,670,095

G

EYA transcriptional coactivator and phosphatase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:66,902,961...67,238,149
Ensembl chr 8:66,902,972...67,060,567

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

severity

protein:increased expression:prostate gland (human)

NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573

G

coagulation factor V

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872

G

fatty acid binding protein 5

mRNA:increased expression:prostate (human)

NCBI chr 8:76,696,899...76,701,459

G

family with sequence similarity 13 member C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:71,898,392...72,038,998
Ensembl chr 9:71,923,477...72,040,371

G

family with sequence similarity 83 member C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:56,191,896...56,199,786
Ensembl chr 2:56,192,688...56,198,758

G

FA complementation group A

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:10094191 PMID:24728327 PMID:25741868 PMID:26181256 PMID:28492532 More...

NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591

G

failed axon connections homolog, metaxin like GST domain containing

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:74,525,175...74,596,948
Ensembl chr13:74,525,691...74,594,703

G

F-box DNA helicase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:6,001,071...6,047,512
Ensembl chr 9:6,013,908...6,047,753

G

fibrillin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:31,204,652...31,476,677
Ensembl chr23:31,204,391...31,475,820

G

F-box and leucine rich repeat protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:34,575,889...34,682,308
Ensembl chr27:34,580,426...34,625,036

G

FYVE, RhoGEF and PH domain containing 1

protein:increased expression:prostate gland (human)

NCBI chr X:50,554,648...50,609,437
Ensembl chr X:50,556,168...50,583,010

G

FYVE, RhoGEF and PH domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:35,112,453...35,136,161
Ensembl chr17:35,112,815...35,136,017

G

fibroblast growth factor 7

mRNA:increased expression:prostate gland stroma, hormone insensitive tumors

NCBI chr26:33,802,349...33,867,743
Ensembl chr26:33,802,328...33,867,333

G

fibroblast growth factor receptor 1

disease_progression

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

fibroblast growth factor receptor 2

no_association
disease_progression

DNA:mutation,polymorphism:exons:no mutations or polymorphisms found in patient or cell line DNA to explain changes in expression seen in other studies
mRNA:splice variant::shift from Fgfr2IIIb to Fgfr2IIIc in malignancy, restoration of Fgfr2IIIb slows growth
mRNA:increased expression:prostate gland
mRNA:alternative form:prostate:switch from isoform IIIb to IIIc
mRNA:decreased expression:prostate:isoforms IIIb and IIIc, decrease in IIIb associated with progression to androgen-independence

PMID:9285567 PMID:9537256 PMID:11069376 PMID:11170144 PMID:12111699

RGD:2289086 RGD:2289728 RGD:2289746 RGD:2289845 RGD:2289859

NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704

G

fibroblast growth factor receptor 4

disease_progression

DNA:SNP:exon 9: 288G>A, p.G388R (human)

NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456

G

FHF complex subunit HOOK interacting protein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:58,592,828...58,625,732
Ensembl chr 1:58,592,886...58,626,272

G

fragile histidine triad diadenosine triphosphatase

DNA:SNP:intron:increased risk in carriers of minor allele of SNP rs760317
DNA:hypermethylation:promoter:methylation percentage 15% in tumors vs no methylation in nonmalignant prostate
DNA:SNP:intron:reduced risk in carriers of minor allele of SNP rs760317

PMID:11839671 PMID:15705877 PMID:17548701

RGD:2289869 RGD:2289878 RGD:2289896

NCBI chr22:21,006,010...22,474,056

G

fms related receptor tyrosine kinase 3

NCBI chr 3:7,117,579...7,222,600
Ensembl chr 3:7,116,947...7,222,849

G

forkhead box O1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors, also lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707

G

forkhead box O3

mRNA:decreased expression:tumor:lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725

G

formyl peptide receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,568,338...44,574,614
Ensembl chr 6:44,568,501...44,569,559

G

FRAS1 related extracellular matrix 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:17,121,063...17,310,149
Ensembl chr 3:17,129,126...17,300,363

G

gamma-aminobutyric acid type A receptor subunit beta2

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr23:63,636,094...63,894,587
Ensembl chr23:63,637,109...63,893,370

G

gamma-aminobutyric acid type A receptor subunit gamma1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:4,133,320...4,224,366
Ensembl chr27:4,133,161...4,219,122

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:30,458,076...30,470,139
Ensembl chr 6:30,458,383...30,470,139

G

growth differentiation factor 10

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:44,066,979...44,080,319
Ensembl chr 9:44,067,469...44,079,522

G

GEN1 Holliday junction 5' flap endonuclease

ClinVar Annotator: match by term: GEN1-related prostate cancer

PMID:25741868 PMID:28492532

NCBI chr14:89,886,102...89,917,485
Ensembl chr14:89,888,853...89,911,293

G

guided entry of tail-anchored proteins factor 3, ATPase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:11,426,857...11,437,343
Ensembl chr 6:11,426,787...11,437,119

G

GDNF family receptor alpha 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:40,927,283...40,948,591
Ensembl chr23:40,927,289...40,946,023

G

GLI family zinc finger 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,371,929...53,384,339
Ensembl chr11:53,375,558...53,385,269

G

glyceronephosphate O-acyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:68,518,643...68,553,055
Ensembl chr25:68,518,300...68,553,767

G

golgi membrane protein 1

protein,mRNA:increased expression:prostate

NCBI chr12:96,706,865...96,778,687
Ensembl chr12:96,708,548...96,779,065

G

gephyrin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:43,702,384...44,421,890
Ensembl chr24:43,880,344...44,422,276

G

G protein-coupled receptor 26

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:116,329,336...116,353,073
Ensembl chr 9:116,329,419...116,351,784

G

G protein-coupled receptor 55

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:116,945,216...116,967,559
Ensembl chr10:116,947,905...116,948,864

G

G protein-coupled receptor 82

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:38,918,871...38,932,011
Ensembl chr X:38,930,844...38,931,854

G

growth factor receptor bound protein 2

treatment
disease_progression

DNA:amplification, mutation

PMID:17372910 PMID:28930697

RGD:13504750 RGD:13504751

NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156

G

glutamate ionotropic receptor delta type subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:45,485,219...46,265,186

G

glutamate ionotropic receptor NMDA type subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231

G

glutamate metabotropic receptor 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:95,264,905...96,060,822
Ensembl chr21:95,264,765...96,050,554

G

gastrin releasing peptide

protein:increased expression:serum (human)

NCBI chr18:20,496,201...20,508,551
Ensembl chr18:20,496,516...20,507,153

G

glutamate rich WD repeat containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:41,707,669...41,715,293
Ensembl chr 6:41,707,743...41,714,425

G

glutathione S-transferase pi 1

susceptibility

DNA:polymorphism:exon:p.I105V (human)

PMID:9111193 PMID:17067754

RGD:4142515 RGD:6906883

NCBI chr 1:6,676,897...6,679,936

G

glucuronidase beta

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:1,679,682...1,699,238

G

heme binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:34,985,834...34,995,037
Ensembl chr13:34,986,129...34,994,809

G

HEPACAM family member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:55,788,028...55,829,876
Ensembl chr21:55,788,084...55,824,890

G

HHIP like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:77,602,306...77,633,281
Ensembl chr24:77,602,532...77,632,232

G

hypoxia inducible factor 1 subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

G

homeodomain interacting protein kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:34,834,526...34,848,751
Ensembl chr 6:34,835,059...34,848,138

G

histone cell cycle regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:6,324,050...6,424,999
Ensembl chr19:6,324,253...6,425,641

G

HLF transcription factor, PAR bZIP family member

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:38,048,114...38,108,798
Ensembl chr16:38,048,097...38,108,725

G

hemicentin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:43,230,265...43,677,315
Ensembl chr25:43,231,328...43,554,097

G

heterogeneous nuclear ribonucleoprotein K

protein:increased expression:prostate gland (human)

NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743

G

homeobox B13

mRNA:increased expression:prostate gland

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:41,537,122...41,581,994
Ensembl chr15:41,537,837...41,581,929

G

5-hydroxytryptamine receptor 2C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:102,190,355...102,499,928
Ensembl chr X:102,325,731...102,497,278

G

5-hydroxytryptamine receptor 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:123,229,239...123,244,360
Ensembl chr21:123,229,816...123,241,481

G

HtrA serine peptidase 2

mRNA, protein:increased expression:prostate (human)

NCBI chr14:32,745,436...32,749,176
Ensembl chr14:32,743,708...32,748,577

G

inhibitor of Bruton tyrosine kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:6,836,527...6,915,731
Ensembl chr13:6,834,532...6,915,778

G

intercellular adhesion molecule 1

NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263

G

interferon induced with helicase C domain 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264

G

intraflagellar transport 43

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:53,231,293...53,329,116
Ensembl chr24:53,231,300...53,329,109

G

insulin like growth factor 1 receptor

disease_progression

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

insulin like growth factor 2 receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116

G

insulin like growth factor binding protein 3

severity
no_association

DNA:SNP:promoter:rs2854744, homozygous C allele associated with 2x increased risk
DNA:SNP:promoter:rs2854744 C allele associated with low grade tumors only, odds ratio=4.1 for low grade vs 1.0 for high grade
DNA:SNP:promoter:no association with rs2854744, 440 cases and 480 related controls from Cleveland, OH and Detroit, MI

PMID:15006930 PMID:17668637 PMID:17724372

RGD:2290008 RGD:2290012 RGD:2290015

NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205

G

inhibitor of nuclear factor kappa B kinase subunit beta

protein:increased serine phosphorylation:prostate gland

NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381

G

interleukin 16

DNA:SNP:exon:rs4072111 (human)

NCBI chr26:2,080,985...2,208,764
Ensembl chr26:2,077,228...2,208,431

G

interleukin 33

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436

G

integrin linked kinase

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
protein:decreased expression:tumor:significantly lower in benign prostatic hyperplasia then any prostate cancer (p<0.01), gradient of expression from BPH to poorly differentiated C+D stage neoplasms

PMID:15704679 PMID:18336616

RGD:2301729 RGD:2301731

NCBI chr 1:58,214,630...58,221,770
Ensembl chr 1:58,213,310...58,221,217

G

interphotoreceptor matrix proteoglycan 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:79,560,987...79,664,906
Ensembl chr22:79,561,498...79,660,472

G

inhibitor of growth family member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:6,683,994...6,696,888
Ensembl chr11:6,684,897...6,696,852

G

inhibin subunit alpha

mRNA,protein:decreased expression:malignant tumors

NCBI chr10:105,467,575...105,471,388
Ensembl chr10:105,467,963...105,471,688

G

indolethylamine N-methyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:27,635,727...27,707,463
Ensembl chr21:27,634,903...27,639,800

G

insulin

disease_progression

NCBI chr 1:1,965,128...1,969,090

G

integrator complex subunit 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,037,176...10,085,499

G

integrator complex subunit 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:89,790,758...89,846,764
Ensembl chr 8:89,790,758...89,850,755

G

immunity related GTPase Q

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:37,111,782...37,116,258
Ensembl chr 6:37,112,015...37,115,322

G

integrin subunit alpha D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:28,095,341...28,128,498

G

integrin subunit beta 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:45,506,355...45,650,979
Ensembl chr10:45,504,987...45,595,543

G

inter-alpha-trypsin inhibitor heavy chain 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:7,621,779...7,723,731
Ensembl chr 9:7,617,999...7,723,662

G

ITPRIP like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:745,194...748,203
Ensembl chr14:745,331...750,727

G

Janus kinase 1

severity

DNA:frameshift mutations

NCBI chr20:68,122,134...68,253,361
Ensembl chr20:68,122,173...68,252,042

G

junction plakoglobin

severity

DNA,mRNA,protein:loss of heterozygosity, decreased expression:tumor:relative to either BPH or normal prostate
protein:increased expression:tumor:significantly associated with capsular invasion (p=0.007 for all cases, p=0.015 for cases with Gleason score 5-7)

PMID:10206308 PMID:15781623

RGD:2291864 RGD:2291876

NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322

G

lysine acetyltransferase 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:43,508,888...43,548,411
Ensembl chr16:43,510,483...43,548,517

G

katanin catalytic subunit A1 like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:33,848,471...33,967,832
Ensembl chr18:33,848,748...33,907,092

G

potassium voltage-gated channel modifier subfamily F member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:96,695,647...96,698,931
Ensembl chr14:96,695,961...96,697,445

G

potassium inwardly rectifying channel subfamily J member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:119,971,282...120,040,752
Ensembl chr 1:119,969,370...119,986,411

G

potassium inwardly rectifying channel subfamily J member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659

G

potassium calcium-activated channel subfamily N member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:8,961,833...9,124,728
Ensembl chr20:8,962,302...9,124,166

G

potassium voltage-gated channel subfamily Q member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:126,566,288...126,921,354
Ensembl chr 8:126,566,545...126,622,712

G

potassium voltage-gated channel subfamily Q member 5

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:1,932,962...2,495,926
Ensembl chr17:1,930,803...2,128,570

G

lysine demethylase 3A

mRNA:increased expression:prostate gland (human)
mRNA:increased expression:prostate (human)

PMID:20127736 PMID:22120715

RGD:9586733 RGD:9587486

NCBI chr14:20,668,215...20,721,854
Ensembl chr14:20,668,821...20,720,759

G

lysine demethylase 4A

mRNA:increased expression:prostate (human)

NCBI chr20:89,108,090...89,164,657
Ensembl chr20:89,073,876...89,164,663

G

lysine demethylase 4B

mRNA:increased expression:prostate (human)

NCBI chr 6:4,649,140...4,831,634
Ensembl chr 6:4,649,221...4,831,636

G

lysine demethylase 4C

severity

mRNA:increased expression:prostate gland (human)

NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666

G

lysine demethylase 5A

mRNA:decreased expression:prostate gland (human)

NCBI chr11:285,206...381,481
Ensembl chr11:286,728...381,430

G

lysine demethylase 5B

severity

mRNA:increased expression:prostate gland (human)

NCBI chr25:26,599,740...26,685,256
Ensembl chr25:26,600,736...26,683,632

G

lysine demethylase 6A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:42,053,272...42,291,013
Ensembl chr X:42,053,336...42,290,526

G

kinase insert domain receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771

G

KIAA1755 ortholog

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:25,490,719...25,540,750
Ensembl chr 2:25,504,610...25,540,756

G

kinesin family member 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:25,486,907...25,495,445
Ensembl chr12:25,487,832...25,495,557

G

kinesin family member 16B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:45,189,908...45,495,837
Ensembl chr 2:45,189,756...45,495,725

G

kinesin family member 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr11:53,458,795...53,493,801

G

KLF transcription factor 6

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

G

kelch like family member 20

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:55,407,648...55,473,195
Ensembl chr25:55,405,713...55,473,175

G

kallikrein related peptidase 10

susceptibility

DNA:SNP:exon:p.A50S (human)

NCBI chr 6:44,034,371...44,039,966
Ensembl chr 6:44,034,682...44,038,607

G

kallikrein related peptidase 13

protein:decreased expression:prostate

NCBI chr 6:44,069,309...44,085,681
Ensembl chr 6:44,069,324...44,083,884

G

kallikrein related peptidase 4

protein:increased expression:prostate gland

PMID:12370833 PMID:17545602

RGD:2314854 RGD:2314857

NCBI chr 6:43,921,920...43,935,224
Ensembl chr 6:43,922,052...43,934,253

G

kallikrein related peptidase 6

protein:decreased expression:prostate

NCBI chr 6:43,980,680...43,991,873
Ensembl chr 6:43,980,701...43,990,060

G

killin, p53 regulated DNA replication inhibitor

ClinVar Annotator: match by term: Prostate cancer

PMID:25741868 PMID:27535533

NCBI chr 9:81,304,883...81,307,162

G

lysine methyltransferase 2A

mRNA:decreased expression:prostate gland (human)

NCBI chr 1:109,819,748...109,912,763
Ensembl chr 1:109,853,758...109,908,113

G

lysine methyltransferase 2B

mRNA:decreased expression:prostate gland (human)

NCBI chr 6:30,626,723...30,648,204
Ensembl chr 6:30,626,848...30,647,883

G

lysine methyltransferase 2C

mRNA:decreased expression:prostate gland (human)

NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137

G

lysine methyltransferase 2D

mRNA:decreased expression:prostate gland (human)

NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423

G

lysine methyltransferase 2E (inactive)

mRNA:decreased expression:prostate gland (human)

NCBI chr21:73,930,957...74,030,434
Ensembl chr21:73,930,932...74,029,673

G

lysine methyltransferase 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:118,712,964...118,743,322
Ensembl chr11:118,723,029...118,743,325

G

kinetochore associated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:117,866,814...117,966,297
Ensembl chr11:117,869,711...117,963,907

G

keratinocyte proline rich protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,955,183...10,959,767
Ensembl chr20:10,955,971...10,957,707

G

KRAS proto-oncogene, GTPase

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

keratin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:48,810,671...48,817,436
Ensembl chr11:48,810,677...48,816,363

G

keratin 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:64,669,805...64,677,091
Ensembl chr16:64,670,844...64,677,001

G

laminin subunit alpha 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:1,872,740...1,930,037
Ensembl chr 2:1,872,832...1,929,854

G

La ribonucleoprotein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:75,189,782...75,343,852
Ensembl chr 7:75,204,960...75,342,059

G

ligand dependent nuclear receptor corepressor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:90,009,449...90,157,340
Ensembl chr 9:90,152,909...90,156,646

G

lymphoid enhancer binding factor 1

associated with prostate cancer

NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110

G

DNA ligase 4

treatment

NCBI chr 3:86,576,200...86,587,097
Ensembl chr 3:86,577,304...86,580,039

G

lectin, mannose binding 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:8,645,361...8,659,139
Ensembl chr26:8,646,256...8,658,576

G

leishmanolysin like peptidase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:91,676,060...91,745,251
Ensembl chr15:91,676,379...91,744,928

G

arylamine N-acetyltransferase 1

susceptibility

DNA:polymorphism

NCBI chr 8:16,302,296...16,315,406
Ensembl chr 8:16,314,446...16,315,318

G

olfactory receptor 6K2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:5,221,383...5,224,559

G

glutathione S-transferase Mu 1

NCBI chr20:23,854,969...23,861,634

G

ATP-binding cassette sub-family A member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:2,171,487...2,218,851

G

solute carrier family 25 member 47

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:78,285,089...78,292,562
Ensembl chr24:78,285,593...78,292,773

G

olfactory receptor 2T1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:85,325,169...85,330,931

G

cadherin-1

disease_progression
susceptibility

protein:decreased expression:prostate gland
DNA:polymorphism:promoter:-160C>A (human)
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to

RGD
OMIM
ClinVar

PMID:1722187 PMID:2403327 PMID:2449335 PMID:8075649 PMID:9537325 More...

RGD:2289487 RGD:2289493

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

zinc finger protein 100

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:19,712,698...19,755,896

G

olfactory receptor 1S2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:15,053,977...15,055,511

G

zinc finger protein 776

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:50,123,668...50,135,933

G

serine/threonine-protein kinase Sgk3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:62,587,494...62,732,766
Ensembl chr 8:62,647,303...62,732,868

G

mucin-6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:822,052...858,589

G

myosin-8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:9,733,585...9,765,740
Ensembl chr16:9,733,717...9,763,255

G

cyclic nucleotide gated channel subunit alpha 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:2,273,540...2,313,083
Ensembl chr27:2,293,765...2,312,761

G

mismatch repair endonuclease PMS2

disease_progression

NCBI chr28:15,174,359...15,209,962
Ensembl chr28:15,172,100...15,209,852

G

lon peptidase 2, peroxisomal

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:34,050,284...34,160,363
Ensembl chr 5:34,050,446...34,160,165

G

LDL receptor related protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776

G

LDL receptor related protein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111

G

LDL receptor related protein 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:12,016,542...12,170,496
Ensembl chr11:12,021,560...12,170,663

G

LDL receptor related protein associated protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:45,206,455...45,225,766
Ensembl chr27:45,206,618...45,225,767

G

leucine rich repeat containing 37 member A3

ClinVar Annotator: match by term: Malignant tumor of prostate

G

microtubule actin crosslinking factor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:93,413,111...93,814,388

G

mitotic arrest deficient 1 like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:11423979 PMID:25741868

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:69,460,345...70,916,684

G

MAM domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:81,104,453...81,285,287
Ensembl chr12:81,105,126...81,285,531

G

mastermind like transcriptional coactivator 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:81,456,537...81,508,893
Ensembl chr23:81,496,033...81,506,497

G

mastermind like domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:124,955,942...125,093,874
Ensembl chr X:125,025,375...125,083,319

G

mitogen-activated protein kinase kinase 5

protein:increased expression

NCBI chr26:15,694,760...15,956,814
Ensembl chr26:15,693,811...15,956,918

G

mitogen-activated protein kinase kinase 7

mRNA:splice variant:exon 2: (human)

NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398

G

mitogen-activated protein kinase kinase kinase 7

DNA:deletion

NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832

G

mitogen-activated protein kinase 10

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:34,394,600...34,725,658
Ensembl chr 7:34,399,544...34,564,212

G

mitogen-activated protein kinase 7

NCBI chr16:17,962,827...17,969,027
Ensembl chr16:17,964,408...17,968,714

G

microtubule associated protein tau

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:59,894,400...60,020,723
Ensembl chr16:59,890,221...59,955,612

G

MCC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:16,309,574...16,773,736
Ensembl chr23:16,310,968...16,579,343

G

mediator complex subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

G

matrix metallopeptidase 13

disease_progression

protein:increased expression:plasma:higher concentration in patients with metastases vs non-metastatic PCa, BPH or control patients

NCBI chr 1:94,322,473...94,370,665
Ensembl chr 1:94,322,979...94,334,747

G

matrix metallopeptidase 15

disease_progression

NCBI chr 5:43,961,288...43,982,182
Ensembl chr 5:43,960,891...43,982,261

G

matrix metallopeptidase 2

disease_progression

protein:increased expression:prostate gland

NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004

G

matrix metallopeptidase 7

NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587

G

mitochondrial ribosomal protein L46

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:7,025,380...7,033,219
Ensembl chr29:7,025,442...7,033,219

G

mutS homolog 2

disease_progression

NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819

G

mutS homolog 6

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:28492532

NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174

G

microseminoprotein beta

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 9:41,796,948...41,810,373
Ensembl chr 9:41,803,922...41,810,276

G

macrophage scavenger receptor 1

susceptibility

DNA:SNPs
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:12244320 PMID:12958598 PMID:17903305 PMID:21791690 PMID:24082139 More...

NCBI chr 8:14,221,389...14,305,059
Ensembl chr 8:14,220,529...14,304,946

G

MDM2 binding protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:115,023,272...115,109,948
Ensembl chr 8:115,029,029...115,102,088

G

methylenetetrahydrofolate reductase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

G

mitochondrial nucleoid associated protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:48,388,665...48,404,425
Ensembl chr16:48,386,342...48,403,958

G

mechanistic target of rapamycin kinase

treatment

NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020

G

mucin 1, cell surface associated

severity

NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962

G

MX dynamin like GTPase 1

susceptibility

DNA:SNP:promoter:-g.88G>T (rs2071430) (human)

NCBI chr 2:85,333,327...85,368,179
Ensembl chr 2:85,338,530...85,368,507

G

MAX interactor 1, dimerization protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:103,131,534...103,211,609
Ensembl chr 9:103,131,420...103,209,231

G

matrix remodeling associated 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:1,525,422...1,563,711

G

MYC proto-oncogene, bHLH transcription factor

susceptibility
severity

DNA:snp:intron:IVS1-355T>A rs3891248 (human)
protein:increased expression:prostate gland (human)

PMID:18483343 PMID:20140016

RGD:7207432 RGD:7240541

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

MYC binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:56,128,691...56,412,854
Ensembl chr 3:56,128,428...56,412,923

G

myosin heavy chain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532 PMID:31030430

NCBI chr16:9,966,801...9,999,458
Ensembl chr16:9,966,922...9,994,402

G

myosin light chain kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464

G

myosin XVI

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:86,850,362...87,550,840

G

myosin XVIIIA

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:22,836,856...22,942,366

G

myosin IA

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:52,939,744...52,961,957
Ensembl chr11:52,936,090...52,961,486

G

myosin VI

protein:increased expression:prostate gland epithelium, perinuclear region of cytoplasm

NCBI chr13:527,361...620,418
Ensembl chr13:457,495...618,858

G

myocardin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:11,923,464...12,100,897
Ensembl chr16:12,000,197...12,095,552

G

myotilin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:40,542,153...40,567,873
Ensembl chr23:40,548,100...40,568,217

G

myelin regulatory factor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:12,066,277...12,103,091

G

NSF attachment protein beta

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:52,379,633...52,395,274

G

N-acetyltransferase 2

susceptibility

DNA:polymorphism

NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621

G

nibrin

susceptibility

DNA:deletion, loss of heterozygosity
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:14973119 PMID:23265383 PMID:23555315 PMID:25741868 PMID:26467025 More...

NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028

G

nuclear receptor coactivator 1

disease_progression

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

G

nuclear receptor coactivator 2

mRNA:increased expression:prostate (human)

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

G

nuclear receptor coactivator 3

mRNA:increased expression:prostate (human)

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

G

nuclear receptor coactivator 4

severity

protein:increased expression:prostate gland
mRNA:decreased expression:prostate gland

PMID:12368219 PMID:15166229

RGD:2293534 RGD:2293535

NCBI chr 9:41,813,018...41,836,974
Ensembl chr 9:41,826,320...41,837,505

G

NECAP endocytosis associated 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:115,865,118...115,882,157
Ensembl chr20:115,864,746...115,882,392

G

NIMA related kinase 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:52,297,211...52,342,359
Ensembl chr24:52,296,261...52,342,724

G

negative elongation factor complex member C/D

disease_progression

NCBI chr 2:5,146,137...5,159,965
Ensembl chr 2:5,146,575...5,159,883

G

neural EGFL like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:43,416,052...44,335,894
Ensembl chr 1:43,415,553...44,335,381

G

neuropilin and tolloid like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:32,929,091...32,991,240
Ensembl chr 5:32,930,692...32,979,561

G

nuclear factor kappa B subunit 1

susceptibility
treatment

DNA:SNPs, haplotype: :multiple
DNA:indel:promoter

PMID:26068031 PMID:26788504 PMID:28797847

RGD:11054182 RGD:11554936 RGD:13506729

NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498

G

NFKB inhibitor alpha

disease_progression
susceptibility
no_association

protein:increased serine phosphorylation
ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:SNPs:promoter:-826C>T, -881A>G (human)
DNA:SNPs: :rs2233406, rs3138053 (human)
DNA:polymorphism:3' UTR

PMID:23093296 PMID:26068031 PMID:26834482

RGD:11054182 RGD:13506766 RGD:13506767

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

NHS actin remodeling regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr X:15,803,386...16,183,809
Ensembl chr X:16,168,609...16,183,787

G

NK3 homeobox 1

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

G

NLR family pyrin domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr16:4,930,643...4,983,378

G

NLR family pyrin domain containing 7

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19066229 PMID:21507883 PMID:24105752

NCBI chr 6:47,534,730...47,560,380
Ensembl chr 6:47,539,594...47,552,265

G

NMD3 ribosome export adaptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:29,592,847...29,765,928
Ensembl chr15:29,592,577...29,621,567

G

nitric oxide synthase 3

disease_progression

DNA:polymorphism:exon:p.E298D (human)

NCBI chr21:119,174,829...119,196,840

G

notch receptor 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:7732783 PMID:15364702 PMID:16328531 PMID:23265383 PMID:25033846 More...

NCBI chr 6:13,762,570...13,803,676
Ensembl chr 6:13,761,512...13,793,359

G

nuclear receptor subfamily 3 group C member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

G

NRAS proto-oncogene, GTPase

disease_progression

NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931

G

netrin 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:91,052,142...91,172,463
Ensembl chr11:91,051,662...91,172,522

G

NACHT and WD repeat domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:15,255,116...15,318,589
Ensembl chr 6:15,221,120...15,318,470

G

8-oxoguanine DNA glycosylase

susceptibility

DNA:missense mutation:exon:p.S326C (1245C>G) (rs1052133) (human)
DNA:missense mutation:cds:p.S326C (human)

PMID:19914098 PMID:24649009

RGD:8657136 RGD:8657378

NCBI chr22:45,757,414...45,763,690

G

oncoprotein induced transcript 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:58,338,703...58,378,492
Ensembl chr 9:58,337,958...58,377,734

G

Obg like ATPase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:59,589,475...59,766,259

G

olfactomedin like 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:19,676,162...19,679,013
Ensembl chr20:19,676,132...19,679,124

G

OXA1L mitochondrial inner membrane protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:23,131,273...23,137,470
Ensembl chr29:23,131,453...23,137,245

G

p21 (RAC1) activated kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:33,715,695...33,769,272
Ensembl chr 6:33,759,462...33,770,497

G

PALM2 and AKAP2 fusion

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:29,371,705...29,908,100
Ensembl chr12:29,371,209...29,604,909

G

par-3 family cell polarity regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:33,396,738...34,104,479
Ensembl chr 9:33,396,246...33,803,997

G

protocadherin beta 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:43,680,654...43,734,646

G

pecanex 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:48,113,578...48,314,005
Ensembl chr24:48,113,348...48,312,922

G

phosphodiesterase 1C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:26,094,604...26,712,127
Ensembl chr21:26,501,264...26,598,053

G

phosphodiesterase 3A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:20,235,814...20,545,740
Ensembl chr11:20,236,430...20,540,900

G

phosphodiesterase 6B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:48,117,495...48,168,727
Ensembl chr27:48,118,190...48,162,368

G

phosphodiesterase 7B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:37,230,419...37,560,391
Ensembl chr13:37,226,606...37,378,218

G

platelet derived growth factor receptor beta

NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234

G

pyruvate dehydrogenase kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776

G

pyruvate dehyrogenase phosphatase catalytic subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:52,575,280...52,583,614
Ensembl chr 5:52,580,423...52,582,009

G

3-phosphoinositide dependent protein kinase 1

treatment

G

phosphatidylethanolamine binding protein 1

NCBI chr11:113,469,845...113,479,177

G

pyroglutamyl-peptidase I

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:16,818,743...16,837,565
Ensembl chr 6:16,818,643...16,836,949

G

PHD finger protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:103,959,502...104,055,711
Ensembl chr12:104,007,498...104,055,711

G

PHD finger protein 8

mRNA:increased expression:prostate (human)

NCBI chr X:50,058,687...50,172,827
Ensembl chr X:50,058,273...50,172,086

G

PH domain and leucine rich repeat protein phosphatase 1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)

NCBI chr18:16,786,128...17,051,250

G

phosphatidylinositol glycan anchor biosynthesis class H

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:44,790,528...44,848,870
Ensembl chr24:44,838,242...44,848,598

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15647370 PMID:15805248 More...

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

disease_progression
treatment

PMID:18372911 PMID:20103642

RGD:13506809 RGD:13506810

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496

G

phosphoinositide-3-kinase regulatory subunit 1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:18336616 PMID:23265383

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

G

phosphoinositide-3-kinase regulatory subunit 2

NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937

G

paired like homeodomain 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:58,501,669...58,526,413
Ensembl chr 7:58,501,559...58,507,318

G

polycystin 2 like 1, transient receptor potential cation channel

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:93,319,408...93,363,389

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:20,411,746...20,873,601

G

plasminogen activator, urokinase

severity

protein:increased expression:serum (human)

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

G

phospholipase B1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:78,960,601...79,122,082
Ensembl chr14:78,960,202...79,096,555

G

phospholipase C beta 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:28,650,604...29,059,435
Ensembl chr 2:28,650,421...28,915,290

G

pleckstrin homology domain containing A4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,076,695...42,110,904

G

pleckstrin homology and RhoGEF domain containing G1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:78,034,968...78,285,288
Ensembl chr13:78,154,150...78,287,996

G

pleckstrin homology and RhoGEF domain containing G4B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:10,284...129,774

G

prostate transmembrane protein, androgen induced 1

disease_progression

NCBI chr 2:6,403,358...6,465,958
Ensembl chr 2:6,404,515...6,465,982

G

pancreatic lipase related protein 1

NCBI chr 9:109,397,970...109,417,422
Ensembl chr 9:109,399,227...109,417,351

G

podocan

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:79,834,491...79,858,606
Ensembl chr20:79,834,497...79,858,087

G

DNA polymerase kappa

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:26046662

NCBI chr 4:69,842,887...69,948,285
Ensembl chr 4:69,872,752...69,948,249

G

DNA polymerase nu

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:46,523,052...46,694,474

G

paraoxonase 1

protein:increased activity:serum (human)

NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875

G

diphosphoinositol pentakisphosphate kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:6,562,435...6,639,330
Ensembl chr23:6,571,657...6,641,002

G

protein phosphatase 1 regulatory subunit 3C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:84,918,592...84,923,281
Ensembl chr 9:84,918,591...84,923,334

G

protein phosphatase 2 catalytic subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280

G

protein phosphatase 2 regulatory subunit B'gamma

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:79,703,316...79,875,379
Ensembl chr24:79,703,312...79,875,389

G

protein phosphatase 6 regulatory subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:32,824,732...32,917,356
Ensembl chr19:32,866,039...32,916,534

G

PPARG related coactivator 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:95,157,759...95,183,031
Ensembl chr 9:95,157,800...95,183,037

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

protein:increased expression:prostate, lymph node

NCBI chr 2:15,152,001...15,354,556
Ensembl chr 2:15,152,096...15,354,544

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,781,892...64,061,222
Ensembl chr 8:63,781,948...64,060,864

G

peripherin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:29,429,876...29,456,013
Ensembl chr17:29,430,545...29,453,636

G

proteasome 26S subunit, ATPase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:67,979,449...67,995,103

G

phosphatase and tensin homolog

disease_progression
susceptibility

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
DNA:deletion

RGD
OMIM
ClinVar

PMID:9259288 PMID:9399897 PMID:9467011 PMID:9856571 PMID:10232405 More...

RGD:2292502 RGD:2301729

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

prostaglandin-endoperoxide synthase 2

susceptibility

DNA:SNP:promoter:-1195G>A (human)

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

G

protein tyrosine kinase 2

protein:increased expression:prostate gland

NCBI chr 8:134,897,511...135,246,300

G

protein tyrosine kinase 2 beta

severity

protein:decreased expression:prostate gland

NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782

G

protein tyrosine phosphatase non-receptor type 21

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:66,102,081...66,191,918
Ensembl chr24:66,101,788...66,187,987

G

protein tyrosine phosphatase non-receptor type 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:30,048,941...30,168,816
Ensembl chr12:30,083,128...30,171,473

G

protein tyrosine phosphatase receptor type D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:70,160,253...71,237,292
Ensembl chr12:70,693,214...71,239,437

G

protein tyrosine phosphatase receptor type N2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:125,655,787...126,622,503

G

pyrroline-5-carboxylate reductase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:137,823,685...137,830,630
Ensembl chr 8:137,826,293...137,830,546

G

pyrin and HIN domain family member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:4,967,123...5,006,172
Ensembl chr20:4,967,224...5,006,035

G

RAB11 family interacting protein 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:24,851,474...24,991,482
Ensembl chr16:24,851,595...24,991,361

G

RAB33A, member RAS oncogene family

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:105,421,709...105,437,206
Ensembl chr X:105,424,290...105,437,169

G

Rac family small GTPase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:19,930,799...19,949,381
Ensembl chr19:19,929,892...19,949,376

G

RAD50 double strand break repair protein

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:26467025 PMID:28492532 PMID:33339169

NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622

G

Raf-1 proto-oncogene, serine/threonine kinase

disease_progression

NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020

G

Rap guanine nucleotide exchange factor like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:65,978,561...65,995,738

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:89,191,220...89,294,746
Ensembl chr10:89,192,772...89,250,757

G

RAS protein activator like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:50,838,985...51,211,683
Ensembl chr25:50,840,184...50,941,942

G

Ras association domain family member 1

disease_progression

DNA:hypermethylation:promoter

NCBI chr22:11,716,969...11,728,646
Ensembl chr22:11,716,918...11,725,027

G

RB transcriptional corepressor 1

DNA:loss of heterozygosity

NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546

G

RB associated KRAB zinc finger

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:16,594,449...16,648,577

G

regulator of chromosome condensation 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:115,139,279...115,171,872

G

RERG like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:17,928,575...17,938,408
Ensembl chr11:17,928,557...17,938,351

G

Rho related BTB domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:21,069,255...21,098,000
Ensembl chr 8:21,079,411...21,097,026

G

RIPOR family member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

G

ring finger protein, LIM domain interacting

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:64,178,159...64,205,759

G

ribonuclease L

ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to

PMID:11799394 PMID:12415269 PMID:16609730 PMID:25741868 PMID:28492532

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

ribosomal protein L10 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:23,667,440...23,669,041
Ensembl chr24:23,668,304...23,668,948

G

ribosomal protein S6 kinase C1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:16,298,782...16,510,108
Ensembl chr25:16,297,144...16,510,023

G

RNA pseudouridine synthase domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:704,649...708,025
Ensembl chr 5:704,519...708,058

G

regulator of telomere elongation helicase 1

susceptibility

DNA:SNP:cds:rs2297441|rs3208008 (human)

NCBI chr 2:531,905...567,430
Ensembl chr 2:531,085...566,840

G

rubicon like autophagy enhancer

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:24,400,507...24,445,514
Ensembl chr 3:24,399,500...24,430,601

G

RUN domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:63,297,669...63,313,397
Ensembl chr16:63,299,545...63,313,306

G

S100 calcium binding protein A3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,249,332...10,256,671
Ensembl chr20:10,255,515...10,256,318

G

scaffold attachment factor B2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:5,244,072...5,281,053
Ensembl chr 6:5,244,000...5,280,932

G

strawberry notch homolog 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:118,633,151...118,702,472
Ensembl chr11:118,634,332...118,677,415

G

sodium channel epithelial 1 subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337

G

secernin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:28,386,910...28,456,556
Ensembl chr21:28,408,528...28,456,558

G

signal peptide, CUB domain and EGF like domain containing 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:36,871,032...36,910,583
Ensembl chr17:36,875,410...36,910,091

G

sidekick cell adhesion molecule 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:17,354,106...18,316,238
Ensembl chr28:17,351,241...17,998,205

G

serpin family B member 13

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:16,163,247...16,175,953
Ensembl chr18:16,165,054...16,173,438

G

SET domain containing 5

severity

NCBI chr22:45,391,871...45,475,183
Ensembl chr22:45,430,660...45,475,217

G

SET domain bifurcated histone lysine methyltransferase 1

mRNA, protein:increased expression:prostate gland (human)

G

seizure related 6 homolog like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:9,069,476...9,284,540
Ensembl chr19:9,069,746...9,284,543

G

splicing factor 3b subunit 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:53,673,443...53,724,485
Ensembl chr 5:53,673,455...53,725,615

G

small G protein signaling modulator 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:1,970,412...2,012,417
Ensembl chr16:1,970,456...2,014,384

G

SHC binding and spindle associated 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:46,424,943...46,473,336
Ensembl chr25:46,426,312...46,473,218

G

sucrase-isomaltase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:24,480,060...24,582,468
Ensembl chr15:24,482,865...24,582,394

G

sialic acid binding Ig like lectin 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,367,499...44,405,288
Ensembl chr 6:44,367,624...44,382,790

G

sirtuin 1

disease_progression

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

G

SKI3 subunit of superkiller complex

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:89,346,960...89,438,260
Ensembl chr 4:89,344,526...89,430,070

G

SKI like proto-oncogene

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:19,022,167...19,059,117
Ensembl chr15:19,022,017...19,057,004

G

S-phase kinase associated protein 2

disease_progression

NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632

G

solute carrier family 13 member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr 2:17,233,287...17,324,761
Ensembl chr 2:17,233,346...17,324,951

G

solute carrier family 16 member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:64,023,846...64,123,428
Ensembl chr X:64,023,327...64,125,422

G

solute carrier family 25 member 22

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:593,914...601,603
Ensembl chr 1:593,890...598,585

G

solute carrier family 25 member 32

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:98,256,793...98,271,347
Ensembl chr 8:98,254,852...98,271,514

G

SLC2A4 regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:487,282...490,957
Ensembl chr 2:483,483...490,435

G

solute carrier family 30 member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:106,722,539...106,731,494
Ensembl chr20:106,724,256...106,731,955

G

solute carrier family 34 member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:79,395,923...79,410,835
Ensembl chr23:79,396,250...79,411,695

G

solute carrier family 35 member C1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:19,534,437...19,541,990
Ensembl chr 1:19,530,466...19,541,551

G

solute carrier family 35 member G1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:87,127,367...87,137,526

G

solute carrier family 46 member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:7,802,170...7,819,608
Ensembl chr 3:7,801,728...7,819,584

G

solute carrier family 5 member 2

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:25741868

NCBI chr 5:28,183,141...28,191,352
Ensembl chr 5:28,183,618...28,191,120

G

solute carrier family 5 member 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:11,346,281...11,373,754
Ensembl chr14:11,347,861...11,370,297

G

solute carrier family 6 member 9

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr20:88,774,354...88,809,726
Ensembl chr20:88,774,339...88,808,669

G

solute carrier family 8 member A3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:47,287,487...47,428,608
Ensembl chr24:47,288,256...47,427,776

G

solute carrier organic anion transporter family member 1B3

disease_progression

mRNA,protein:increased expression:prostate (human)

NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161

G

SMAD family member 3

disease_progression

protein:increased expression:tumor:significantly elevated in 53/67 (79%, p=0.0002) overall, in 23/35 with Gleason score 6-7(66%) and 30/32 with Gleason score 8-10 (94%, p=0.0062); by immunohistochemistry

NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527

G

SMAD family member 9

protein:altered localization

NCBI chr 3:15,369,119...15,444,599
Ensembl chr 3:15,372,933...15,405,836

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

disease_progression

NCBI chr12:77,364,468...77,546,356
Ensembl chr12:77,375,500...77,546,314

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

no_association
disease_progression

absence of somatic mutations in the samples used

PMID:12684665 PMID:17075831

RGD:2302527 RGD:2302528

NCBI chr 6:9,943,162...10,044,476

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:52,103,075...52,131,070
Ensembl chr11:52,104,345...52,131,079

G

single-strand-selective monofunctional uracil-DNA glycosylase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:50,292,780...50,307,828
Ensembl chr11:50,289,154...50,300,492

G

small nuclear ribonucleoprotein polypeptide E

severity

mRNA:increased expression:prostate gland (human)

NCBI chr25:25,474,620...25,483,427

G

suppressor of cytokine signaling 1

DNA:hypermethylation

NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991

G

sorbin and SH3 domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:88,475,783...88,729,912
Ensembl chr 9:88,472,946...88,729,851

G

sortilin related VPS10 domain containing receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:99,581,375...100,171,637

G

SOS Ras/Rac guanine nucleotide exchange factor 1

NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895

G

SRY-box transcription factor 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898

G

spermatogenesis associated 18

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:16,342,176...16,388,458
Ensembl chr 7:16,340,607...16,387,995

G

sperm antigen with calponin homology and coiled-coil domains 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:7,488,821...7,539,961
Ensembl chr19:7,488,832...7,539,952

G

serine peptidase inhibitor Kazal type 1

severity

protein:increased expression:prostate gland, serum

NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814

G

speckle type BTB/POZ protein

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:26619011

NCBI chr16:69,990,554...70,073,241

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

protein:increased tyrosine phosphorylation:prostate gland, membrane

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

G

steroid 5 alpha-reductase 1

disease_progression

protein:increased expression:prostate gland
mRNA:increased expression:prostate gland (rat)

PMID:16818707 PMID:17720776

RGD:2302521 RGD:2302523

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

G

steroid 5 alpha-reductase 2

susceptibility

DNA:missense mutation:cds:p.A49T (human)
mRNA:decreased expression:prostate gland

PMID:10501358 PMID:12949937

RGD:2302560 RGD:4891929

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

G

sterol regulatory element binding transcription factor 2

disease_progression

NCBI chr19:24,364,725...24,439,851
Ensembl chr19:24,364,911...24,440,014

G

single stranded DNA binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:75,561,872...75,882,924
Ensembl chr 4:75,562,625...75,882,845

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:17,269,548...17,400,860

G

signal transducer and activator of transcription 3

treatment

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

G

signal transducer and activator of transcription 5A

disease_progression

DNA:CNV: :prostate (human)

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

G

signal transducer and activator of transcription 6

disease_progression

mRNA, protein:increased expression:fibromuscular stroma, malignant epithelia:correlated with high histological grade and increased tumor size

NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203

G

syntaxin 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:8,613,551...8,937,428

G

syntaxin binding protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:10,440,061...10,519,798
Ensembl chr12:10,439,801...10,519,777

G

SUFU negative regulator of hedgehog signaling

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 9:95,532,228...95,660,594
Ensembl chr 9:95,532,242...95,657,290

G

sulfotransferase family 2A member 1

no_association
severity

DNA:missense mutations:cds:p.A63P (187G>C), p.A261T (781G>A) (human)
DNA:SNP:intron: (rs2547238) (human)

PMID:16617014 PMID:22542949

RGD:6893648 RGD:6893649

NCBI chr 6:41,160,707...41,175,382
Ensembl chr 6:41,159,978...41,175,300

G

synaptic vesicle glycoprotein 2B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:9,691,421...9,875,657
Ensembl chr29:9,806,570...9,872,782

G

synaptonemal complex protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:4,214,713...4,283,451
Ensembl chr 2:4,226,063...4,282,751

G

synaptogyrin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,924,110...21,957,453
Ensembl chr19:21,924,174...21,953,808

G

TAO kinase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:113,485,871...113,717,213
Ensembl chr11:113,484,330...113,704,271

G

taste 2 receptor member 20

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:10,935,490...10,938,807
Ensembl chr11:10,936,104...10,937,030

G

transcription factor 3

severity

NCBI chr 6:1,393,147...1,440,515
Ensembl chr 6:1,393,107...1,440,479

G

transcription factor 7

severity

NCBI chr23:36,919,648...36,953,088
Ensembl chr23:36,919,745...36,951,192

G

transcription factor 7 like 2

disease_progression

DNA:SNP: :rs7903146 (human)
DNA:SNPs: :rs7094463, rs10749127, rs11196224 (human)

PMID:24961829 PMID:25678841

RGD:13506821 RGD:13506825

NCBI chr 9:105,828,834...106,047,810

G

telomerase reverse transcriptase

mRNA:increased expression:plasma

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

testis expressed 14, intercellular bridge forming factor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:34,709,039...34,849,855
Ensembl chr16:34,746,004...34,849,781

G

transferrin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149

G

trefoil factor 1

disease_progression

mRNA:increased expression:prostate gland
protein:increased expression:plasma

PMID:10458410 PMID:16467092

RGD:2291999 RGD:2298571

NCBI chr 2:86,239,101...86,244,491
Ensembl chr 2:86,239,105...86,243,795

G

trefoil factor 2

disease_progression

protein:increased expression:plasma

NCBI chr 2:86,223,113...86,228,964

G

transferrin receptor

protein:increased expression:serum

NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584

G

thyroglobulin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:127,293,797...127,567,218
Ensembl chr 8:127,293,834...127,567,771

G

transforming growth factor beta 1

protein:increased expression:prostate gland

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

G

transforming growth factor beta receptor 2

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

G

transforming growth factor beta receptor 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:41,353,182...41,565,357
Ensembl chr20:41,353,325...41,565,343

G

thrombospondin 1

mRNA:decreased expression:prostate gland

NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812

G

thrombospondin 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:8,621,706...8,640,252
Ensembl chr20:8,622,812...8,640,532

G

thyroid hormone receptor beta

DNA:loss of heterozygosity (human)

NCBI chr15:68,797,410...69,161,256
Ensembl chr15:68,802,078...68,902,292

G

TIMP metallopeptidase inhibitor 2

disease_progression

DNA, protein:hypermethylation, decreased expression:promoter, prostate gland
protein:increased expression:prostate gland

PMID:17325663 PMID:18329693

RGD:2290389 RGD:2290397

NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471

G

TIMP metallopeptidase inhibitor 3

disease_progression

mRNA:decreased expression:prostate gland

NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449

G

toll like receptor 2

susceptibility

DNA:deletion:promoter:−196_−174del (human)

NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795

G

transmembrane and coiled-coil domains 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:45,001,265...45,040,160
Ensembl chr26:45,023,323...45,038,035

G

transmembrane protein with EGF like and two follistatin like domains 2

disease_progression

DNA:hypermethylation

PMID:15299075 PMID:16458425 PMID:16500022

RGD:2290485 RGD:2290486 RGD:2290490

NCBI chr10:77,491,041...77,735,890
Ensembl chr10:77,490,095...77,735,849

G

transmembrane protein 183A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:26,329,213...26,346,850
Ensembl chr25:26,328,841...26,346,750

G

transmembrane protein 230

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:32,955,522...32,968,578
Ensembl chr 2:32,955,538...32,969,152

G

transmembrane protein 94

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:46,178,237...46,223,931
Ensembl chr16:46,177,181...46,202,463

G

tumor necrosis factor

G

TNF receptor superfamily member 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:119,656,183...119,736,151
Ensembl chr20:119,657,614...119,715,078

G

DNA topoisomerase II alpha

NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:47,702,638...47,714,309
Ensembl chr12:47,702,995...47,714,338

G

tumor protein p53

disease_progression

DNA:mutations:exon
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:1467311 PMID:1565144 PMID:2750177 PMID:7887414 PMID:7969167 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

G

tumor protein p63

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:28492532

NCBI chr15:83,861,489...84,126,675

G

tumor protein p73

mRNA:alternative forms

NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691

G

tripartite motif containing 28

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:50,820,188...50,826,376
Ensembl chr 6:50,819,833...50,827,010

G

tripartite motif containing 34

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:61,104,681...61,123,901

G

tripartite motif containing 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:61,040,908...61,067,815
Ensembl chr 1:61,040,928...61,069,356

G

tripartite motif family like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:133,998,623...134,009,606
Ensembl chr 7:134,001,323...134,009,241

G

thyroid hormone receptor interactor 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:115,789,978...115,946,978
Ensembl chr10:115,789,605...115,945,753

G

transient receptor potential cation channel subfamily C member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:47,827,295...47,909,207
Ensembl chr15:47,827,247...47,909,202

G

transient receptor potential cation channel subfamily C member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:16,135,822...16,358,902

G

transient receptor potential cation channel subfamily M member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:81,608,301...82,616,349
Ensembl chr12:81,609,229...81,925,984

G

transformation/transcription domain associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:14,154,962...14,289,110
Ensembl chr28:14,154,960...14,286,512

G

tumor susceptibility 101

mRNA:alternative forms:cds:multiple

NCBI chr 1:46,401,889...46,451,122
Ensembl chr 1:46,402,024...46,450,916

G

teashirt zinc finger homeobox 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:26,334,239...26,409,597

G

translin associated factor X interacting protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:59,611,229...59,631,212
Ensembl chr 5:59,609,692...59,630,985

G

tetraspanin 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:46,610,841...46,788,761
Ensembl chr 7:46,609,602...46,788,704

G

unc-51 like autophagy activating kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:18,335,095...18,434,031
Ensembl chr16:18,335,235...18,433,578

G

uromodulin like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:85,894,102...86,023,577
Ensembl chr 2:85,959,746...86,019,950

G

unc-79 homolog, NALCN channel complex subunit

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:71,172,214...71,455,415
Ensembl chr24:71,209,614...71,456,568

G

URB2 ribosome biogenesis homolog

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:66,893,033...66,926,921
Ensembl chr25:66,893,112...66,929,487

G

upstream transcription factor 2, c-fos interacting

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:30,202,224...30,212,783
Ensembl chr 6:30,202,375...30,213,058

G

usherin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:13,171,499...13,950,553
Ensembl chr25:13,173,576...13,947,724

G

ubiquitin specific peptidase 28

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:105,175,116...105,257,163
Ensembl chr 1:105,175,067...105,257,102

G

ubiquitin specific peptidase 48

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:110,854,966...110,958,140
Ensembl chr20:110,854,758...110,960,529

G

UV radiation resistance associated

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:67,032,575...67,353,207
Ensembl chr 1:67,032,436...67,353,166

G

versican

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 4:77,581,627...77,692,495
Ensembl chr 4:77,593,449...77,690,616

G

voltage dependent anion channel 1

DNA:SNP: :rs7250897 (human)

NCBI chr23:36,783,670...36,817,071

G

vitamin D receptor

susceptibility

DNA:SNP: :rs11574143 (human)

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

G

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

G

vitamin K epoxide reductase complex subunit 1 like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:1,535,346...1,617,484

G

vanin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:40,756,307...40,776,538
Ensembl chr13:40,762,296...40,776,872

G

WD repeat and FYVE domain containing 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:33,031,762...33,331,475
Ensembl chr 7:33,030,069...33,237,701

G

WD repeat domain 49

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:21,778,500...21,967,551

G

WAP four-disulfide core domain 1

disease_progression

mRNA:decreased expression:prostate gland
protein:decreased expression, increased expression:connective tissue, epithelium

PMID:15305341 PMID:15305342

RGD:2291859 RGD:2291860

NCBI chr 5:69,700,984...69,734,682
Ensembl chr 5:69,701,470...69,731,823

G

WNT inhibitory factor 1

mRNA, protein:decreased expression:prostate gland

NCBI chr11:60,728,316...60,800,181
Ensembl chr11:60,727,948...60,799,960

G

Wnt family member 2

mRNA:decreased expression:prostate gland

NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730

G

WWC family member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

G

X-linked inhibitor of apoptosis

disease_progression

protein:increased expression:prostate gland

PMID:17947468 PMID:19415464

RGD:2315849 RGD:2315852

G

X-ray repair cross complementing 1

susceptibility

DNA:polymorphism: :p.R399Q

NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094

G

YTH N6-methyladenosine RNA binding protein C2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:16,800,515...16,880,983
Ensembl chr23:16,800,558...16,880,952

G

zinc finger DHHC-type palmitoyltransferase 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:5,591,311...5,607,448
Ensembl chr19:5,589,090...5,607,387

G

zinc finger homeobox 3

susceptibility

DNA:deletion (human)
DNA, mRNA:mutations, decreased expression: :multiple, prostate gland (human)

PMID:15750593 PMID:16637072

RGD:2315694 RGD:2315695

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

G

zinc finger with KRAB and SCAN domains 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:13,013,603...13,064,154
Ensembl chr28:13,044,616...13,056,332

G

zinc finger matrin-type 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:10,374,093...10,434,212
Ensembl chr15:10,373,904...10,430,759

G

zinc finger protein 136

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:10,984,818...11,012,092

G

zinc finger protein 184

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:45,046,492...45,068,236
Ensembl chr17:45,061,170...45,071,256

G

zinc finger protein 287

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:15,087,895...15,107,194

G

zinc finger protein 304

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:49,754,839...49,763,281

G

zinc finger protein 419

ClinVar Annotator: match by term: Malignant tumor of prostate

G

zinc finger protein 48

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:27,069,694...27,074,692
Ensembl chr 5:27,070,309...27,074,731

G

zinc finger protein 534

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:45,201,650...45,208,617

G

zinc finger protein 560

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:8,632,432...8,675,720
Ensembl chr 6:8,632,708...8,641,252

G

zinc finger protein 772

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:49,856,459...49,862,922

G

zona pellucida glycoprotein 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:75,002,053...75,010,764
Ensembl chr25:75,002,344...75,010,323

G

zinc finger and SCAN domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:3,746,183...3,770,586
Ensembl chr29:3,744,923...3,769,890

Prostate Cancer, Hereditary, 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12068308 PMID:12460918 PMID:12460919 PMID:14679157 PMID:15035987 More...

NCBI chr21:109,495,525...109,690,261

G

homeobox B13

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9536098 PMID:17576681 PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:17056636 PMID:17468812 PMID:17704260 PMID:18386799 PMID:20949621 More...

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9467011 PMID:9600246 PMID:10051160 PMID:12786840 PMID:16773562 More...

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

ribonuclease L

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:11799394 PMID:12415269 PMID:16609730 PMID:25741868 PMID:28492532

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

tumor protein p53

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12826609 PMID:20522432 PMID:25741868 PMID:27545002 PMID:28492532 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

Prostate Cancer, Hereditary, 12

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EH domain binding protein 1

ClinVar Annotator: match by term: Prostate cancer, hereditary, 12

NCBI chr14:43,971,400...44,293,615
Ensembl chr14:43,971,261...44,292,365

Prostate Cancer, Hereditary, 13

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

microseminoprotein beta

ClinVar Annotator: match by term: Prostate cancer, hereditary, 13

PMID:18264096 PMID:18264097 PMID:19153072 PMID:19383797 PMID:19644707

NCBI chr 9:41,796,948...41,810,373
Ensembl chr 9:41,803,922...41,810,276

Prostate Cancer, Hereditary, 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

elaC ribonuclease Z 2

ClinVar Annotator: match by term: Prostate cancer, hereditary, 2

PMID:10986046 PMID:11175785 PMID:11254448 PMID:11507049 PMID:12515253 More...

NCBI chr16:12,328,864...12,353,916
Ensembl chr16:12,329,300...12,353,872

Prostate Cancer, Hereditary, 9

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

homeobox B13

ClinVar Annotator: match by term: Prostate cancer, hereditary, 9

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

Prostate Cancer, Somatic

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:1631125 PMID:1779964 PMID:6541981 PMID:7723794 PMID:7795646 More...

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

checkpoint kinase 2

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:12533788 PMID:16835864 PMID:16941491 PMID:18058223 PMID:18996005 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

KLF transcription factor 6

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

G

mitotic arrest deficient 1 like 1

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:11423979 PMID:25741868

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

zinc finger homeobox 3

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

Prostate Cancer/Brain Cancer Susceptibility

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EPH receptor B2

susceptibility

ClinVar Annotator: match by term: Prostate cancer/brain cancer susceptibility

PMID:15300251 PMID:16155194 PMID:25741868 PMID:28492532

NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777

prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 2

treatment

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

angiopoietin 1

protein:increased expression:prostate gland

NCBI chr 8:102,020,346...102,268,443

G

activating transcription factor 4

treatment

NCBI chr19:22,092,046...22,094,184
Ensembl chr19:22,091,667...22,095,230

G

alpha-2-glycoprotein 1, zinc-binding

exacerbates

NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363

G

BCL2 associated agonist of cell death

protein:increased expression:prostate gland

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

G

BCL2 associated X, apoptosis regulator

disease_progression

protein:increased expression:prostate gland epithelium

NCBI chr 6:42,186,028...42,193,105

G

BCL2 like 1

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

G

BCL2 like 14

mRNA:decreased expression:prostate gland

NCBI chr11:11,961,329...12,001,903
Ensembl chr11:11,973,010...12,002,128

G

bone morphogenetic protein 2

disease_progression

protein:increased expression:prostate gland

NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901

G

bone morphogenetic protein 4

disease_progression

protein:increased expression:prostate

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

G

caspase 6

mRNA:increased expression:prostate gland

NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489

G

cyclin dependent kinase 13

ameliorates

NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525

G

glycoprotein hormones, alpha polypeptide

mRNA:increased expression:prostate gland

NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093

G

chitinase 3 like 1

severity

protein:increased secretion:serum (human)

NCBI chr25:26,160,993...26,169,005
Ensembl chr25:26,160,961...26,169,566

G

CRK like proto-oncogene, adaptor protein

protein:decreased tyrosine phosphorylation:prostate gland

G

E2F transcription factor 5

ameliorates

NCBI chr 8:80,542,390...80,587,888
Ensembl chr 8:80,542,580...80,587,226

G

eukaryotic translation initiation factor 3 subunit H

DNA:amplification

NCBI chr 8:111,283,184...111,390,835

G

growth hormone releasing hormone

mRNA:increased expression:prostate

NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499

G

histone deacetylase 2

disease_progression

protein:increased expression:prostate gland

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

G

histone deacetylase 3

protein:increased expression:prostate gland

NCBI chr23:44,246,296...44,263,127

G

hydroxymethylbilane synthase

mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.009)

NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095

G

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

inhibin subunit alpha

DNA:hypermethylation,loss of heterozygosity:promoter,genomic region:significant hypermethylation (P<0.001) in tumors vs nonmalignant controls, LOH at 2q32-36 in 42% of cases

NCBI chr10:105,467,575...105,471,388
Ensembl chr10:105,467,963...105,471,688

G

Jun proto-oncogene, AP-1 transcription factor subunit

protein:increased activation:tumor:nuclear localization in 13/16 (81.25%) of BPH and 31/36 (86.1%) of adenocarcinomas (PCa) with significantly stronger staining in PCa (P=0.006)

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

G

nucleoside diphosphate kinase A

NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616

G

MET proto-oncogene, receptor tyrosine kinase

disease_progression

protein:increased expression:primary tumor, metastatic carcinoma (human)

NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093

G

matrix Gla protein

mRNA:increased expression:primary tumor; mRNA:decreased expression:metastatic tissue:decreased or absent expression in metastases and cell lines from metastatic tumors

NCBI chr11:14,776,668...14,780,796
Ensembl chr11:14,776,209...14,780,947

G

marker of proliferation Ki-67

NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866

G

matrix metallopeptidase 7

NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587

G

platelet derived growth factor subunit B

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

G

platelet derived growth factor D

disease_progression

NCBI chr 1:95,293,263...95,551,138
Ensembl chr 1:95,292,193...95,385,199

G

polo like kinase 1

mRNA, protein:increased expression:prostate gland

NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718

G

protein kinase C alpha

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

G

seryl-tRNA synthetase 1

mRNA:decreased expression:prostate gland (human)

G

S-phase kinase associated protein 2

NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632

G

serine peptidase inhibitor, Kunitz type 1

disease_progression

protein:decreased expression:prostate gland (human)

NCBI chr26:42,136,749...42,150,125
Ensembl chr26:42,134,536...42,150,118

G

secreted phosphoprotein 1

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

G

signal transducer and activator of transcription 3

protein:increased activity:prostate gland

PMID:11987152 PMID:18210874

RGD:2291910 RGD:2298538

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

G

signal transducer and activator of transcription 6

protein:increased activity:tumor:significant increase in constitutive activation vs adjacent normal tissue and unrelated normal prostate, by EMSA

NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203

G

transmembrane BAX inhibitor motif containing 6

mRNA:increased expression:prostate gland

NCBI chr11:45,976,689...46,001,021
Ensembl chr11:45,976,700...46,001,457

G

tumor protein p73

disease_progression

mRNA, protein:increased expression:prostate gland

NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691

prostate carcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-methylacyl-CoA racemase

disease_progression

NCBI chr 4:33,221,777...33,244,829
Ensembl chr 4:33,225,754...33,244,836

G

angiogenin

NCBI chr29:21,215,985...21,226,927

G

apurinic/apyrimidinic endodeoxyribonuclease 1

protein:increased expression, altered localization:prostate, cytoplasm

NCBI chr29:20,978,878...20,981,393

G

androgen receptor

CTD Direct Evidence: marker/mechanism

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

amphiregulin

protein:increased expression:prostate gland

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

G

ATM serine/threonine kinase

protein:increased serine phosphorylation:prostate gland

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

aurora kinase A

protein:increased expression:prostate gland

PMID:15754349 PMID:16707419

RGD:2293877 RGD:2293883

NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395

G

aurora kinase B

NCBI chr16:7,571,255...7,583,034
Ensembl chr16:7,570,538...7,582,959

G

BTG anti-proliferation factor 2

protein:decreased expression:prostate gland

NCBI chr25:26,032,404...26,036,500
Ensembl chr25:26,034,632...26,036,538

G

coactivator associated arginine methyltransferase 1

protein:increased expression:prostate gland

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

G

cyclin D1

mRNA, protein:decreased expression:prostate gland

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

G

cyclin E1

mRNA, protein:increased expression:prostate gland

NCBI chr 6:24,879,923...24,888,985

G

cyclin dependent kinase inhibitor 1B

CTD Direct Evidence: therapeutic

PMID:18691549 PMID:20932324

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

G

cAMP responsive element binding protein 3 like 4

severity

NCBI chr20:9,839,137...9,848,413
Ensembl chr20:9,838,085...9,845,287

G

colony stimulating factor 1 receptor

protein:increased expression:prostate gland

NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304

G

cytochrome P450 family 19 subfamily A member 1

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

G

DNA methyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G

estrogen receptor 2

treatment

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G

fibroblast growth factor 6

protein:increased expression:prostate gland

NCBI chr11:4,464,159...4,476,592
Ensembl chr11:4,464,171...4,473,916

G

fibroblast growth factor 8

NCBI chr 9:94,797,157...94,803,725
Ensembl chr 9:94,798,088...94,803,629

G

fibroblast growth factor receptor 1

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

fibroblast growth factor receptor 2

NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704

G

fms related receptor tyrosine kinase 1

protein:decreased expression:prostate gland

NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967

G

frizzled class receptor 4

protein:increased expression:prostate gland

NCBI chr 1:78,164,243...78,199,296
Ensembl chr 1:78,188,630...78,198,187

G

glutathione S-transferase pi 1

CTD Direct Evidence: marker/mechanism

PMID:22581815 PMID:24312188

NCBI chr 1:6,676,897...6,679,936

G

histone deacetylase 1

protein:increased expression:prostate gland

NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556

G

insulin like growth factor 1

protein:increased expression:prostate gland

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

G

KRAS proto-oncogene, GTPase

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

lymphoid enhancer binding factor 1

NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110

G

cadherin-1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

LDL receptor related protein 1

protein:increased expression:prostate gland

NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776

G

mitogen-activated protein kinase kinase 4

disease_progression

protein:increased expression

NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125

G

mitogen-activated protein kinase kinase 6

disease_progression

protein:increased expression

NCBI chr16:52,045,398...52,188,416
Ensembl chr16:52,057,784...52,187,997

G

mitogen-activated protein kinase kinase 7

disease_progression

protein:increased expression

NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398

G

MYC proto-oncogene, bHLH transcription factor

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

prohibitin 1

mRNA, protein:increased expression:prostate gland

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

G

Pim-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr17:34,968,661...34,973,920
Ensembl chr17:34,968,429...34,973,760

G

serine protease 8

disease_progression

mRNA, protein:increased expression:prostate gland

NCBI chr 5:27,820,898...27,827,873
Ensembl chr 5:27,817,830...27,824,926

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

PMID:18268330 PMID:19081794 PMID:22581815

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

prostaglandin-endoperoxide synthase 2

protein:altered localization

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

G

RELA proto-oncogene, NF-kB subunit

protein:increased expression:prostate gland

PMID:15570007 PMID:16278667

RGD:2298767 RGD:2298769

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

G

retinoid X receptor alpha

protein:decreased expression:prostate

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

G

solute carrier family 30 member 4

protein:decreased expression:prostate gland

NCBI chr26:37,692,164...37,732,102
Ensembl chr26:37,692,219...37,731,292

G

SMAD family member 4

protein:increased expression:prostate gland

NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478

G

ST14 transmembrane serine protease matriptase

protein:increased expression:prostate gland

NCBI chr 1:121,238,666...121,290,528
Ensembl chr 1:121,238,643...121,290,007

G

serine/threonine kinase 11

NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136

G

TIMP metallopeptidase inhibitor 4

NCBI chr22:48,134,133...48,140,870
Ensembl chr22:48,134,637...48,140,600

G

DNA topoisomerase II beta

CTD Direct Evidence: marker/mechanism

NCBI chr15:70,266,267...70,332,079
Ensembl chr15:70,266,601...70,332,824

G

tumor protein p63

protein:decreased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:17189982 PMID:17982114 PMID:22581815

RGD:2315433 RGD:2315434

NCBI chr15:83,861,489...84,126,675

prostate malignant phyllodes tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

kallikrein related peptidase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 6:43,905,684...43,911,925

prostate small cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma

PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 PMID:15689453 More...

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

Term paths to the root

Path 1
Term	Annotations
disease	15273
disease of anatomical entity	14893
reproductive system disease	2885
male reproductive system disease	1912
prostate disease	1280
Prostatic Neoplasms	1266
prostate cancer +	805
prostatic adenoma	0
Path 2
Term	Annotations
disease	15273
disease of anatomical entity	14893
Urogenital Diseases	4663
Male Urogenital Diseases	1912
male reproductive system disease	1912
prostate disease	1280
Prostatic Neoplasms	1266
prostate cancer +	805
prostatic adenoma	0

paths to the root