BIRC6 (baculoviral IAP repeat containing 6) - Rat Genome Database

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Gene: BIRC6 (baculoviral IAP repeat containing 6) Chlorocebus sabaeus
Analyze
Symbol: BIRC6
Name: baculoviral IAP repeat containing 6
RGD ID: 18385048
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); ubiquitin conjugating enzyme activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN cell population proliferation (ortholog); labyrinthine layer development (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH adrenocortical carcinoma (ortholog); autism spectrum disorder (ortholog); cholangiocarcinoma (ortholog); FOUND IN endosome (inferred); membrane (inferred); microtubule organizing center (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: baculoviral IAP repeat-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11474,879,597 - 75,138,462 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1474,878,700 - 75,138,441 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BIRC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11474,879,597 - 75,138,462 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1474,878,700 - 75,138,441 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BIRC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38232,357,023 - 32,618,878 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl232,357,023 - 32,619,571 (+)EnsemblGRCh38hg38GRCh38
GRCh37232,582,091 - 32,843,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36232,435,600 - 32,697,470 (+)NCBINCBI36Build 36hg18NCBI36
Build 34232,493,964 - 32,754,622NCBI
Celera232,426,891 - 32,688,789 (+)NCBICelera
Cytogenetic Map2p22.3NCBI
HuRef232,320,949 - 32,583,634 (+)NCBIHuRef
CHM1_1232,512,260 - 32,774,075 (+)NCBICHM1_1
T2T-CHM13v2.0232,405,536 - 32,667,526 (+)NCBIT2T-CHM13v2.0
Birc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391774,835,247 - 75,010,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1774,835,290 - 75,010,351 (+)EnsemblGRCm39 Ensembl
GRCm381774,528,254 - 74,703,356 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1774,528,295 - 74,703,356 (+)EnsemblGRCm38mm10GRCm38
MGSCv371774,927,635 - 75,103,113 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361774,433,277 - 74,608,126 (+)NCBIMGSCv36mm8
Celera1778,838,153 - 79,014,648 (+)NCBICelera
Cytogenetic Map17E2NCBI
cM Map1745.64NCBI
Birc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8626,474,843 - 26,668,275 (-)NCBIGRCr8
mRatBN7.2620,722,922 - 20,916,396 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl620,722,922 - 20,916,434 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx621,052,875 - 21,246,458 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0621,368,724 - 21,562,308 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0620,849,173 - 21,042,748 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0621,900,763 - 22,092,484 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl621,950,100 - 22,092,346 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0631,789,563 - 31,980,891 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4620,655,186 - 20,848,961 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1620,657,539 - 20,852,541 (-)NCBI
Celera620,282,854 - 20,476,452 (-)NCBICelera
Cytogenetic Map6q13NCBI
Birc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955441739,567 - 922,959 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955441740,299 - 923,920 (+)NCBIChiLan1.0ChiLan1.0
BIRC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21293,877,633 - 94,140,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A93,881,889 - 94,144,897 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A32,373,479 - 32,633,088 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A33,084,892 - 33,344,219 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A33,084,929 - 33,343,245 (+)Ensemblpanpan1.1panPan2
BIRC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11725,618,262 - 25,847,920 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1725,617,892 - 25,847,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1725,409,075 - 25,638,461 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01726,180,036 - 26,412,717 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11725,479,687 - 25,710,494 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01725,551,633 - 25,782,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01725,651,296 - 25,881,986 (+)NCBIUU_Cfam_GSD_1.0
Birc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629269,724,144 - 69,936,276 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936493899,961 - 1,115,493 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936493903,295 - 1,115,434 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BIRC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3107,012,986 - 107,269,477 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13107,012,967 - 107,269,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23113,955,900 - 114,112,369 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Birc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473813,991,022 - 14,246,225 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473813,990,997 - 14,246,741 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 33 18 60
Low 3 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007970997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007970998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007970999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005243294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_492500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000009671   ⟹   ENSCSAP00000007781
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1474,878,700 - 75,138,441 (-)Ensembl
RefSeq Acc Id: XM_007970997   ⟹   XP_007969188
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11474,879,597 - 75,138,462 (-)NCBI
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007971000   ⟹   XP_007969191
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11474,879,597 - 75,138,462 (-)NCBI
Vero_WHO_p1.0NW_02366604536,937,369 - 37,192,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007971001   ⟹   XP_007969192
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11474,879,597 - 75,138,462 (-)NCBI
Vero_WHO_p1.0NW_02366604536,937,369 - 37,192,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007971002   ⟹   XP_007969193
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11474,879,597 - 75,138,462 (-)NCBI
Vero_WHO_p1.0NW_02366604536,937,369 - 37,192,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007971003   ⟹   XP_007969194
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11474,879,597 - 75,138,462 (-)NCBI
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038006767   ⟹   XP_037862695
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
RefSeq Acc Id: XM_038006768   ⟹   XP_037862696
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
RefSeq Acc Id: XM_038006769   ⟹   XP_037862697
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
RefSeq Acc Id: XM_038006770   ⟹   XP_037862698
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
RefSeq Acc Id: XM_038006772   ⟹   XP_037862700
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,192,673 (+)NCBI
RefSeq Acc Id: XR_005243294
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604536,936,136 - 37,167,686 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007969193   ⟸   XM_007971002
- Peptide Label: isoform X7
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007969192   ⟸   XM_007971001
- Peptide Label: isoform X6
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007969191   ⟸   XM_007971000
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007969194   ⟸   XM_007971003
- Peptide Label: isoform X9
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007969188   ⟸   XM_007970997
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007781   ⟸   ENSCSAT00000009671
RefSeq Acc Id: XP_037862695   ⟸   XM_038006767
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862697   ⟸   XM_038006769
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862696   ⟸   XM_038006768
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862698   ⟸   XM_038006770
- Peptide Label: isoform X8
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862700   ⟸   XM_038006772
- Peptide Label: isoform X10
- UniProtKB: A0A0D9RGP2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011594 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009671.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro BIR_rpt UniProtKB/TrEMBL
  BIRC6 UniProtKB/TrEMBL
  UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
KEGG Report csab:103220526 UniProtKB/TrEMBL
NCBI Gene BIRC6 ENTREZGENE
PANTHER (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME UniProtKB/TrEMBL
  BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
Pfam BIR UniProtKB/TrEMBL
  BIRC6 UniProtKB/TrEMBL
  UQ_con UniProtKB/TrEMBL
PROSITE BIR_REPEAT_2 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
SMART BIR UniProtKB/TrEMBL
  UBCc UniProtKB/TrEMBL
Superfamily-SCOP Inhibitor of apoptosis (IAP) repeat UniProtKB/TrEMBL
  SSF54495 UniProtKB/TrEMBL
UniProt A0A0D9RGP2 ENTREZGENE, UniProtKB/TrEMBL