REC8 (REC8 meiotic recombination protein) - Rat Genome Database

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Gene: REC8 (REC8 meiotic recombination protein) Chlorocebus sabaeus
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Symbol: REC8
Name: REC8 meiotic recombination protein
RGD ID: 18742786
Description: ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN double-strand break repair via homologous recombination (ortholog); fertilization (ortholog); homologous chromosome pairing at meiosis (ortholog); ASSOCIATED WITH azoospermia (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); FOUND IN cohesin complex (inferred); condensed chromosome (inferred); condensed chromosome, centromeric region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: meiotic recombination protein REC8 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,157,135 - 1,165,927 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
REC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,157,135 - 1,165,927 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
REC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,172,080 - 24,180,923 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,171,853 - 24,180,257 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,641,289 - 24,649,460 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,711,074 - 23,719,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,711,073 - 23,719,302NCBI
Celera144,505,702 - 4,513,934 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,756,236 - 4,764,468 (+)NCBIHuRef
CHM1_11424,639,883 - 24,648,115 (+)NCBICHM1_1
T2T-CHM13v2.01418,370,390 - 18,378,718 (+)NCBIT2T-CHM13v2.0
Rec8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,855,459 - 55,862,852 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,855,494 - 55,862,852 (+)EnsemblGRCm39 Ensembl
GRCm381455,618,002 - 55,625,395 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,618,037 - 55,625,395 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,237,007 - 56,244,227 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,572,241 - 54,579,461 (+)NCBIMGSCv36mm8
Celera1453,423,239 - 53,430,463 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Rec8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,079,818 - 33,087,283 (+)NCBIGRCr8
mRatBN7.21529,109,862 - 29,117,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,109,863 - 29,117,326 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,955,575 - 30,963,040 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,102,773 - 32,110,240 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,345,115 - 30,352,582 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,296,922 - 34,304,387 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,296,922 - 34,304,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,187,117 - 38,194,582 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,753,772 - 33,761,237 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,769,471 - 33,776,936 (+)NCBI
Celera1528,686,049 - 28,693,447 (+)NCBICelera
Cytogenetic Map15p13NCBI
Rec8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,223,844 - 36,230,948 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,223,783 - 36,231,749 (-)NCBIChiLan1.0ChiLan1.0
REC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,523,163 - 25,534,563 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,741,709 - 24,751,055 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,948,100 - 4,956,492 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,071,724 - 23,079,964 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,071,724 - 23,079,948 (+)Ensemblpanpan1.1panPan2
REC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,165,637 - 4,171,488 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,165,879 - 4,171,486 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,086,993 - 4,093,172 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,276,107 - 4,282,285 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,276,238 - 4,282,280 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,966,501 - 3,972,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,028,327 - 4,034,503 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,290,634 - 4,296,812 (+)NCBIUU_Cfam_GSD_1.0
Rec8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,012,451 - 36,019,615 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722369,423 - 375,243 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722369,366 - 375,243 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,118,744 - 75,125,537 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,118,743 - 75,127,759 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,390,043 - 80,397,865 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rec8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,361,400 - 8,368,347 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,361,345 - 8,369,356 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_007986297   ⟹   XP_007984488
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,157,135 - 1,165,927 (+)NCBI
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,637 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037985482   ⟹   XP_037841410
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBI
RefSeq Acc Id: XM_037985484   ⟹   XP_037841412
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBI
RefSeq Acc Id: XM_037985485   ⟹   XP_037841413
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBI
RefSeq Acc Id: XM_037985488   ⟹   XP_037841416
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,648 (+)NCBI
RefSeq Acc Id: XM_037985492   ⟹   XP_037841420
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,839,860 - 12,848,637 (+)NCBI
RefSeq Acc Id: XM_037985494   ⟹   XP_037841422
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,843,872 - 12,848,648 (+)NCBI
RefSeq Acc Id: XP_007984488   ⟸   XM_007986297
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RU28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037841412   ⟸   XM_037985484
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037841416   ⟸   XM_037985488
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037841410   ⟸   XM_037985482
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037841413   ⟸   XM_037985485
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037841420   ⟸   XM_037985492
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037841422   ⟸   XM_037985494
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016044 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014138.1 UniProtKB/TrEMBL
Gene3D-CATH Structural maintenance of chromosome 1. Chain E UniProtKB/TrEMBL
InterPro Rad21/Rec8-like UniProtKB/TrEMBL
  Rad21/Rec8_C_eu UniProtKB/TrEMBL
  ScpA-like_C UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene REC8 ENTREZGENE
PANTHER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG UniProtKB/TrEMBL
  SCC1 / RAD21 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Rad21_Rec8 UniProtKB/TrEMBL
Superfamily-SCOP Winged helix' DNA-binding domain UniProtKB/TrEMBL
UniProt A0A0D9RU28 ENTREZGENE, UniProtKB/TrEMBL