STXBP1 (syntaxin binding protein 1) - Rat Genome Database

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Gene: STXBP1 (syntaxin binding protein 1) Chlorocebus sabaeus
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Symbol: STXBP1
Name: syntaxin binding protein 1
RGD ID: 18604013
Description: ENCODES a protein that exhibits identical protein binding (ortholog); molecular adaptor activity (ortholog); phospholipase binding (ortholog); INVOLVED IN axon target recognition (ortholog); cellular response to type II interferon (ortholog); developmental process involved in reproduction (ortholog); PARTICIPATES IN insulin secretion pathway; synaptic vesicle exocytosis - neurotransmitter release pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Bardet-Biedl syndrome 1 (ortholog); FOUND IN axon (ortholog); extrinsic component of presynaptic membrane (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: syntaxin-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,440,061 - 10,519,798 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,439,801 - 10,519,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,699,673 - 5,781,129 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STXBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,440,061 - 10,519,798 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,439,801 - 10,519,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,699,673 - 5,781,129 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STXBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,611,912 - 127,696,029 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,579,370 - 127,696,027 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,374,191 - 130,458,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,414,390 - 129,494,816 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,454,121 - 127,534,549NCBI
Celera9101,025,378 - 101,105,881 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef999,990,647 - 100,071,101 (+)NCBIHuRef
CHM1_19130,525,679 - 130,606,190 (+)NCBICHM1_1
T2T-CHM13v2.09139,818,871 - 139,902,984 (+)NCBIT2T-CHM13v2.0
Stxbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,677,619 - 32,737,249 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,677,614 - 32,737,257 (-)EnsemblGRCm39 Ensembl
GRCm38232,787,607 - 32,847,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,787,602 - 32,847,245 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,643,127 - 32,702,757 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,609,971 - 32,669,135 (-)NCBIMGSCv36mm8
Celera232,494,462 - 32,554,183 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Stxbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,474,428 - 36,536,120 (-)NCBIGRCr8
mRatBN7.2316,076,725 - 16,138,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,076,391 - 16,138,369 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,144,972 - 19,206,215 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,729,979 - 27,791,223 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,981,796 - 26,042,989 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,823,779 - 11,885,479 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,823,785 - 11,885,417 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,160,752 - 17,221,893 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,762,105 - 11,825,531 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,658,476 - 11,721,903 (-)NCBI
Celera310,816,317 - 10,877,576 (-)NCBICelera
RH 3.4 Map379.6RGD
Cytogenetic Map3p11NCBI
Stxbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419963,829 - 1,000,759 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419963,829 - 1,000,759 (-)NCBIChiLan1.0ChiLan1.0
STXBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,662,956 - 11,743,095 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,665,339 - 11,745,425 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,731,527 - 98,811,608 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,434,080 - 127,483,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,434,080 - 127,486,152 (+)Ensemblpanpan1.1panPan2
STXBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,690,939 - 55,768,008 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,678,264 - 55,727,680 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,884,147 - 54,958,397 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,612,796 - 56,687,174 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1955,372,644 - 55,447,116 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,687,749 - 55,761,958 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,778,988 - 55,853,304 (-)NCBIUU_Cfam_GSD_1.0
Stxbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,532,283 - 195,598,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,300,952 - 15,365,713 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,300,758 - 15,367,475 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STXBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,116,120 - 268,205,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,116,124 - 268,205,805 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,023,293 - 302,098,188 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Stxbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,842,640 - 7,914,484 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,843,741 - 7,914,444 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSCSAT00000011844   ⟹   ENSCSAP00000009904
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1210,439,801 - 10,519,777 (-)Ensembl
RefSeq Acc Id: XM_008006156   ⟹   XP_008004347
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11210,440,061 - 10,519,798 (-)NCBI
Vero_WHO_p1.0NW_0236660795,699,673 - 5,781,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008006157   ⟹   XP_008004348
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11210,440,061 - 10,519,797 (-)NCBI
Vero_WHO_p1.0NW_0236660795,699,673 - 5,781,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008006158   ⟹   XP_008004349
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11210,440,063 - 10,519,797 (-)NCBI
Vero_WHO_p1.0NW_0236660795,699,673 - 5,781,129 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008004347 (Get FASTA)   NCBI Sequence Viewer  
  XP_008004348 (Get FASTA)   NCBI Sequence Viewer  
  XP_008004349 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009904
  ENSCSAP00000009904.1
RefSeq Acc Id: XP_008004347   ⟸   XM_008006156
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008004348   ⟸   XM_008006157
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RMR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008004349   ⟸   XM_008006158
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCSAP00000009904   ⟸   ENSCSAT00000011844


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013746 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011844.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.60 UniProtKB/TrEMBL
  3.40.50.1910 UniProtKB/TrEMBL
  3.40.50.2060 UniProtKB/TrEMBL
InterPro Sec-1-like_dom1 UniProtKB/TrEMBL
  Sec-1-like_dom2 UniProtKB/TrEMBL
  Sec-1-like_dom3a UniProtKB/TrEMBL
  Sec1-like UniProtKB/TrEMBL
  Sec1-like_sf UniProtKB/TrEMBL
NCBI Gene STXBP1 ENTREZGENE
PANTHER PTHR11679 UniProtKB/TrEMBL
  SYNTAXIN-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam Sec1 UniProtKB/TrEMBL
PIRSF VPS45_Sec1 UniProtKB/TrEMBL
Superfamily-SCOP SSF56815 UniProtKB/TrEMBL
UniProt A0A0D9RMR5 ENTREZGENE, UniProtKB/TrEMBL