GRPR (gastrin releasing peptide receptor)

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Gene: GRPR (gastrin releasing peptide receptor) Chlorocebus sabaeus

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Symbol:

GRPR

Name:

gastrin releasing peptide receptor

RGD ID:

18658218

Description:

ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); neuropeptide binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); learning or memory (ortholog); regulation of cell population proliferation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Memory Disorders (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

gastrin-releasing peptide receptor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	14,569,771 - 14,599,306 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	14,570,453 - 14,599,258 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	16,425,059 - 16,455,086 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Memory Disorders (ISO)

Neurodevelopmental Disorders (ISO)

Prostatic Neoplasms (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA,ISO)

learning or memory (ISO)

motor behavior (IEA)

neuropeptide signaling pathway (IEA)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA)

positive regulation of behavioral fear response (IEA)

positive regulation of respiratory gaseous exchange (IEA)

psychomotor behavior (IEA)

regulation of cell population proliferation (IEA,ISO)

response to external biotic stimulus (IEA)

signal transduction (IEA)

social behavior (IEA,ISO)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled peptide receptor activity (IEA)

G protein-coupled receptor activity (ISO)

neuropeptide binding (ISO)

neuropeptide receptor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GRPR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	14,569,771 - 14,599,306 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	14,570,453 - 14,599,258 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	16,425,059 - 16,455,086 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

GRPR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	16,123,565 - 16,153,518 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	16,123,565 - 16,153,518 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	16,141,688 - 16,171,641 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	16,051,345 - 16,081,562 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	15,901,335 - 15,930,598	NCBI
Celera	X	20,259,707 - 20,289,922 (+)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	13,896,945 - 13,927,133 (+)	NCBI		HuRef
CHM1_1	X	16,172,364 - 16,202,581 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	15,706,468 - 15,736,420 (+)	NCBI		T2T-CHM13v2.0

Grpr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	162,296,900 - 162,332,732 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	162,296,900 - 162,332,673 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	163,513,904 - 163,549,736 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	163,513,904 - 163,549,677 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	159,951,836 - 159,987,579 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	158,858,009 - 158,893,752 (-)	NCBI		MGSCv36	mm8
Celera	X	146,739,026 - 146,774,660 (-)	NCBI		Celera
Cytogenetic Map	X	F5	NCBI
cM Map	X	75.63	NCBI

Grpr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	34,630,238 - 34,670,245 (+)	NCBI		GRCr8
mRatBN7.2	X	30,998,425 - 31,038,442 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	30,998,416 - 31,038,442 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	32,038,434 - 32,078,466 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	35,468,323 - 35,508,331 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	31,669,805 - 31,709,843 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	32,746,259 - 32,786,266 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	32,745,873 - 32,786,359 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	33,083,317 - 33,123,324 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	51,743,248 - 51,783,255 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	51,796,714 - 51,836,724 (+)	NCBI
Celera	X	31,324,305 - 31,364,289 (+)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

Grpr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955519	2,032,500 - 2,063,292 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955519	2,032,500 - 2,063,292 (-)	NCBI	ChiLan1.0	ChiLan1.0

GRPR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	17,916,672 - 17,960,806 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	17,920,074 - 17,949,208 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	8,744,020 - 8,775,085 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	16,099,778 - 16,131,069 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	16,099,778 - 16,131,069 (+)	Ensembl	panpan1.1		panPan2

GRPR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	12,344,704 - 12,381,445 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	12,345,318 - 12,380,915 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	12,194,783 - 12,232,039 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	12,305,424 - 12,342,697 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	12,306,033 - 12,342,171 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	12,374,968 - 12,412,213 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	12,361,417 - 12,398,693 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	12,387,955 - 12,425,227 (+)	NCBI		UU_Cfam_GSD_1.0

Grpr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	5,533,131 - 5,565,860 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	5,533,256 - 5,565,869 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	5,533,256 - 5,565,827 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRPR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	12,659,776 - 12,696,103 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	12,654,059 - 12,711,417 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	13,603,713 - 13,650,148 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Grpr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	907,371 - 939,779 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	907,386 - 946,385 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
72	32	20	33	33	59	19

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007991124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000012937 ⟹ ENSCSAP00000010954

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	X	14,570,453 - 14,599,258 (+)	Ensembl

RefSeq Acc Id:

XM_007991124 ⟹ XP_007989315

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	X	14,569,771 - 14,599,306 (+)	NCBI
Vero_WHO_p1.0	NW_023666056	16,425,059 - 16,455,086 (+)	NCBI

Sequence:

show sequence

CCGGGTGCTATGTGCTTACATGAGAAGCCAAAGGTATCTGTTAAGCTAGGTAGGAACTGCAGTC
GGCTGGTTGCTTCTCATCTGGAGAAAGCAGGCAACTGGGCAGTGATTGAAGTCTCCAGCAGGGG
GCTGGCATTCTCTGTCTATAAGTAACACTGGTTCCTCTTCAAAGCCTCGGCTCAGCGGAGCTGC
TGTTTGCTGGTGAAGCCCGTGACGTGCAAAGCATCCTGCCTATAGGATTTGAGGATTTCTCAGT
GCAGTTTTTTTCTACCCACTTTAAACCTCCAGATTCTAAATATCAGGAAAGACGCTGGGGGAAA
ATAGCAGGCCAAAAGTTCTTAGTAAACTGCAGCCAGGGAGACTCAGACTAGAATGGAGGTAGAA
ATAACTGATGCAGAGTGGGTTTAATTCTAAGCCTTTCTGTGGCTAAGTTTTTGTTGTTGTTAAC
TTATTGAATTTAGAGTTGTATTGCACCGGTCATGTGAAAGCCAGAGCAGCACCAGTGTCAAAAT
AGTGACAGAGAGTTTTGAATACCATAGTTAGTATATATGCACTCAGAGTATTTTTATTAAAGAA
GACAAAGAGTCCAGCACAGATCTCATCTTCATCTTCACTCGGTTGCAAAATCAATAGTTAAGAA
ATAGCATCTAAGGGAACTTTTAGGTGGGAAAAAAATCTAGAGATGGCTCTAAATGACTGTTTCC
TTCTGAACTTGGAAGTGGACCATTTCGTGCACTGCAACATCTCCAATCACAGTGTGGAACTCCC
CGTGAACGACGACTGGTCCCACCCGGGGATCCTCTATGTCATCCCTGCAGTTTATGGGGTTATC
ATTCTGATAGGCCTCATTGGCAACATCACTTTGATCAAGATCTTCTGTACAGTCAAGTCCATGC
GAAACGTTCCAAACCTGTTCATTTCCAGTCTGGCTTTGGGAGACCTGCTCCTCCTAATAACGTG
TGCTCCAGTGGATGCCAGCAGGTACCTGGCTGACAGATGGCTATTTGGCAGGATTGGCTGCAAA
CTGATCCCCTTTATACAGCTTACCTCTGTTGGGGTGTCTGTCTTCACACTCACGGCGCTCTCGG
CAGACAGATACAAAGCCATTGTCCGGCCAATGGATATCCAGGCCTCTCATGCCCTGATGAAGAT
CTGCCTCAAAGCCGCCTTTATCTGGATCATCTCCATGCTGCTGGCCATTCCAGAGGCTGTGTTT
TCTGACCTCCATCCCTTCCATGAGGAAAGCACCAACCAGACCTTCATTAGCTGTGCCCCATACC
CACACTCTAATGAGCTTCACCCCAAAATCCACTCCATGGCTTCCTTTCTGGTCTTCTACGTCAT
CCCACTGTCGATCATCTCCGTTTACTACTACTTCATTGCTAAAAATCTGATCCAGAGTGCTTAC
AATCTTCCCGTGGAAGGGAATATACATGTCAAGAAGCAGATTGAATCCCGGAAGCGACTTGCCA
AGACAGTGCTGGTGTTTGTGGGCCTGTTTGCCTTCTGCTGGCTCCCCAATCACGTCATTTACCT
GTACCGCTCCTACCACTACTCTGAGGTGGACACCTCCATGCTCCACTTTGTCACCAGCATCTGT
GCCCGCCTCCTGGCCTTCACCAACTCCTGCGTGAACCCCTTTGCCCTCTATCTGCTGAGCAAGA
GTTTCAGGAAACAGTTCAACACTCAGCTCCTCTGTTGCCAGCCTGGTCTGATCATCCGGTCTCA
CAGCACTGGAAGGAGTACAACCTGCATGACCTCCCTCAAGAGTACCAACCCCTCCGTGGCCACC
TTTAGCCTCATCAATGGAAACATCTGTCATGAGCGGTATGTCTAGATTGACCCTTGACTTCGCG
CCCTGAAGGACGGTTTTGCTTTATGGCTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007989315	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000010954
	ENSCSAP00000010954.1

RefSeq Acc Id:	XP_007989315 ⟸ XM_007991124
- UniProtKB:	A0A0D9RQR5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000010954 ⟸ ENSCSAT00000012937

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000014850	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000012937.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	Bombsn_rcpt-like	UniProtKB/TrEMBL
	Gastrin_pep_rcpt	UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
NCBI Gene	GRPR	ENTREZGENE
PANTHER	GASTRIN-RELEASING PEPTIDE RECEPTOR	UniProtKB/TrEMBL
	LEUCOKININ RECEPTOR-RELATED	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	BOMBESINR	UniProtKB/TrEMBL
	GASTRINRELPR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A0D9RQR5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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