CASZ1 (castor zinc finger 1) - Rat Genome Database

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Gene: CASZ1 (castor zinc finger 1) Chlorocebus sabaeus
Analyze
Symbol: CASZ1
Name: castor zinc finger 1
RGD ID: 18421054
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell differentiation (ortholog); negative regulation of amacrine cell differentiation (ortholog); negative regulation of glial cell differentiation (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); autism spectrum disorder (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein castor homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,986,451 - 121,144,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605424,935,600 - 25,060,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CASZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,986,451 - 121,144,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605424,935,600 - 25,060,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CASZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38110,636,604 - 10,796,646 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl110,636,604 - 10,796,650 (-)EnsemblGRCh38hg38GRCh38
GRCh37110,696,661 - 10,856,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36110,619,248 - 10,779,294 (-)NCBINCBI36Build 36hg18NCBI36
Celera19,808,055 - 9,967,917 (-)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef19,850,697 - 10,009,398 (-)NCBIHuRef
CHM1_1110,684,386 - 10,844,453 (-)NCBICHM1_1
T2T-CHM13v2.0110,180,201 - 10,340,363 (-)NCBIT2T-CHM13v2.0
Casz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,888,823 - 149,039,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,888,886 - 149,039,346 (+)EnsemblGRCm39 Ensembl
GRCm384148,804,366 - 148,954,893 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,804,429 - 148,954,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,178,501 - 148,329,001 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364147,648,192 - 147,788,930 (+)NCBIMGSCv36mm8
Celera4151,067,937 - 151,218,394 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.87NCBI
Casz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85164,527,083 - 164,677,037 (+)NCBIGRCr8
mRatBN7.25159,243,965 - 159,393,935 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,243,995 - 159,393,400 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05165,625,119 - 165,777,053 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5165,724,027 - 165,774,616 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05169,374,846 - 169,427,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,979,472 - 166,030,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5157,518,835 - 157,666,098 (+)NCBICelera
Cytogenetic Map5q36NCBI
Casz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554862,923,239 - 2,975,835 (+)NCBIChiLan1.0ChiLan1.0
CASZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21217,466,144 - 217,588,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,112,244 - 216,234,246 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v019,396,936 - 9,557,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1110,630,416 - 10,778,567 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl110,622,519 - 10,677,091 (-)Ensemblpanpan1.1panPan2
CASZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1285,194,640 - 85,218,068 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl285,176,161 - 85,232,920 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,769,949 - 81,812,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,903,378 - 85,945,601 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,844,387 - 85,966,963 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1282,650,892 - 82,693,107 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0283,653,486 - 83,695,698 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,716,224 - 84,758,454 (+)NCBIUU_Cfam_GSD_1.0
Casz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,993,178 - 34,009,091 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366234,467,837 - 4,494,390 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366234,478,421 - 4,503,207 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,878,983 - 70,933,357 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,876,329 - 71,029,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,810,472 - 64,828,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Casz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,024,461 - 2,076,551 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,024,553 - 2,078,708 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 18 36
Below cutoff 2 23

Sequence


Reference Sequences
RefSeq Acc Id: XM_007980591   ⟹   XP_007978782
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.120121,088,914 - 121,144,311 (+)NCBI
Vero_WHO_p1.0NW_02366605425,002,149 - 25,057,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007980592   ⟹   XP_007978783
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.120120,986,451 - 121,144,311 (+)NCBI
Vero_WHO_p1.0NW_02366605424,935,600 - 25,060,001 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007978782 (Get FASTA)   NCBI Sequence Viewer  
  XP_007978783 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000017223.1
Reference Protein Sequences
RefSeq Acc Id: XP_007978783   ⟸   XM_007980592
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S8N4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007978782   ⟸   XM_007980591
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S8N4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000000783 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017751.1 UniProtKB/TrEMBL
InterPro CASZ1 UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene CASZ1 ENTREZGENE
PANTHER PTHR12451 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN CASTOR HOMOLOG 1 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
UniProt A0A0D9S8N4 ENTREZGENE, UniProtKB/TrEMBL