Casz1 (castor zinc finger 1) - Rat Genome Database

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Gene: Casz1 (castor zinc finger 1) Mus musculus
Analyze
Symbol: Casz1
Name: castor zinc finger 1
RGD ID: 1557539
MGI Page MGI
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of cell differentiation and retina morphogenesis in camera-type eye. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study chromosome 1p36 deletion syndrome. Orthologous to human CASZ1 (castor zinc finger 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410019P08Rik; AV096627; BC035954; BC040081; ca; castor homolog 1, zinc finger; castor-related protein; cDNA sequence BC035954; Cs; Cst; D4Ertd432; D4Ertd432e; DNA segment, Chr 4, ERATO Doi 432, expressed; MGC31683; zinc finger protein castor homolog 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,888,823 - 149,039,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,888,886 - 149,039,346 (+)EnsemblGRCm39 Ensembl
GRCm384148,804,366 - 148,954,893 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,804,429 - 148,954,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,178,501 - 148,329,001 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364147,648,192 - 147,788,930 (+)NCBIMGSCv36mm8
Celera4151,067,937 - 151,218,394 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
chrysene  (EXP)
Cuprizon  (ISO)
D-glucose  (EXP)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fucoxanthin  (EXP)
fulvestrant  (ISO)
gentamycin  (ISO)
glucose  (EXP)
L-methionine  (EXP)
lead(0)  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood circulation  (IAGP)
abnormal cell cycle checkpoint function  (IAGP)
abnormal fetal cardiomyocyte physiology  (IAGP)
abnormal heart apex morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart right ventricle morphology  (IAGP)
abnormal heart shape  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal lymphatic vessel morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal sarcomere morphology  (IAGP)
abnormal Z line morphology  (IAGP)
congestive heart failure  (IAGP)
decreased fetal cardiomyocyte number  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased mitotic index  (IAGP)
dilated heart right atrium  (IAGP)
distended pericardium  (IAGP)
edema  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged lymphatic vessel  (IAGP)
fetal cardiomyocyte disarray  (IAGP)
globular heart  (IAGP)
heart hypoplasia  (IAGP)
heart right ventricle hypoplasia  (IAGP)
hemorrhage  (IAGP)
increased heart right atrium size  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
liver vascular congestion  (IAGP)
myocardium hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
nuchal edema  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
persistence of hyaloid vascular system  (IEA)
poor circulation  (IAGP)
preweaning lethality, complete penetrance  (IEA)
subcutaneous edema  (IAGP)
thin interventricular septum  (IAGP)
thin myocardium  (IAGP)
thin ventricular wall  (IAGP)
trabecula carnea hypoplasia  (IAGP)
ventricular myocardium compact layer hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12351199   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15226823   PMID:15368895   PMID:15618518   PMID:16141072  
PMID:16141073   PMID:17967808   PMID:18287559   PMID:18799693   PMID:21267068   PMID:21873635   PMID:24194600   PMID:24467707   PMID:25053427   PMID:25190801   PMID:25654255   PMID:25953344  
PMID:26426291   PMID:26913565   PMID:27626380   PMID:28945738   PMID:29467767   PMID:29661797   PMID:29997285   PMID:30072429   PMID:32060262   PMID:32071204   PMID:32325033   PMID:33594190  
PMID:34127677   PMID:35320729   PMID:38355793  


Genomics

Comparative Map Data
Casz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,888,823 - 149,039,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,888,886 - 149,039,346 (+)EnsemblGRCm39 Ensembl
GRCm384148,804,366 - 148,954,893 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,804,429 - 148,954,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,178,501 - 148,329,001 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364147,648,192 - 147,788,930 (+)NCBIMGSCv36mm8
Celera4151,067,937 - 151,218,394 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.87NCBI
CASZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38110,636,604 - 10,796,646 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl110,636,604 - 10,796,650 (-)EnsemblGRCh38hg38GRCh38
GRCh37110,696,661 - 10,856,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36110,619,248 - 10,779,294 (-)NCBINCBI36Build 36hg18NCBI36
Celera19,808,055 - 9,967,917 (-)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef19,850,697 - 10,009,398 (-)NCBIHuRef
CHM1_1110,684,386 - 10,844,453 (-)NCBICHM1_1
T2T-CHM13v2.0110,180,201 - 10,340,363 (-)NCBIT2T-CHM13v2.0
Casz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85164,527,083 - 164,677,037 (+)NCBIGRCr8
mRatBN7.25159,243,965 - 159,393,935 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,243,995 - 159,393,400 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05165,625,119 - 165,777,053 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5165,724,027 - 165,774,616 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05169,374,846 - 169,427,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,979,472 - 166,030,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5157,518,835 - 157,666,098 (+)NCBICelera
Cytogenetic Map5q36NCBI
Casz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554862,923,239 - 2,975,835 (+)NCBIChiLan1.0ChiLan1.0
CASZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21217,466,144 - 217,588,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,112,244 - 216,234,246 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v019,396,936 - 9,557,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1110,630,416 - 10,778,567 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl110,622,519 - 10,677,091 (-)Ensemblpanpan1.1panPan2
CASZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1285,194,640 - 85,218,068 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl285,176,161 - 85,232,920 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,769,949 - 81,812,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,903,378 - 85,945,601 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,844,387 - 85,966,963 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1282,650,892 - 82,693,107 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0283,653,486 - 83,695,698 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,716,224 - 84,758,454 (+)NCBIUU_Cfam_GSD_1.0
Casz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,993,178 - 34,009,091 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366234,467,837 - 4,494,390 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366234,478,421 - 4,503,207 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,878,983 - 70,933,357 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,876,329 - 71,029,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,810,472 - 64,828,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CASZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,986,451 - 121,144,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605424,935,600 - 25,060,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,024,461 - 2,076,551 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,024,553 - 2,078,708 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Casz1
7101 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2016
Count of miRNA genes:786
Interacting mature miRNAs:1048
Transcripts:ENSMUST00000094464, ENSMUST00000122222, ENSMUST00000128881, ENSMUST00000139806, ENSMUST00000140617, ENSMUST00000147270
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
12738431Lfibq20_mliver fibrosis QTL 20 (mouse)4144699835148907426Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse

Markers in Region
BB450868  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384148,954,679 - 148,954,761UniSTSGRCm38
MGSCv374148,328,788 - 148,328,870UniSTSGRCm37
Celera4151,218,181 - 151,218,263UniSTS
Cytogenetic Map4E2UniSTS
cM Map476.4UniSTS
Whitehead/MRC_RH41917.35UniSTS
D4Mit129  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384148,923,159 - 148,923,287UniSTSGRCm38
MGSCv374148,297,268 - 148,297,396UniSTSGRCm37
Celera4151,186,771 - 151,186,903UniSTS
Cytogenetic Map4E2UniSTS
cM Map476.6UniSTS
Whitehead Genetic471.0UniSTS
Whitehead_YAC4 UniSTS
RH124782  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384148,947,612 - 148,947,907UniSTSGRCm38
MGSCv374148,321,721 - 148,322,016UniSTSGRCm37
Celera4151,211,133 - 151,211,428UniSTS
Cytogenetic Map4E2UniSTS
cM Map476.4UniSTS
AV096627  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384148,944,936 - 148,945,022UniSTSGRCm38
MGSCv374148,319,045 - 148,319,131UniSTSGRCm37
Celera4151,208,457 - 151,208,543UniSTS
Cytogenetic Map4E2UniSTS
cM Map476.4UniSTS
Whitehead/MRC_RH41906.04UniSTS
D4Ertd432e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384148,938,501 - 148,938,704UniSTSGRCm38
MGSCv374148,312,610 - 148,312,813UniSTSGRCm37
Celera4151,202,021 - 151,202,224UniSTS
Cytogenetic Map4E2UniSTS
cM Map476.4UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_161310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK010559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL607145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL611967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC075673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI738136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU234132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000094464   ⟹   ENSMUSP00000092035
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4148,888,886 - 149,029,586 (+)Ensembl
GRCm38.p6 Ensembl4148,804,429 - 148,945,129 (+)Ensembl
Ensembl Acc Id: ENSMUST00000122222   ⟹   ENSMUSP00000112978
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4148,888,886 - 149,039,346 (+)Ensembl
GRCm38.p6 Ensembl4148,804,429 - 148,954,889 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128881
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4148,888,922 - 148,924,203 (+)Ensembl
GRCm38.p6 Ensembl4148,804,465 - 148,839,746 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139806   ⟹   ENSMUSP00000120307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4149,017,571 - 149,024,968 (+)Ensembl
GRCm38.p6 Ensembl4148,933,114 - 148,940,511 (+)Ensembl
Ensembl Acc Id: ENSMUST00000140617
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4148,973,838 - 148,976,393 (+)Ensembl
GRCm38.p6 Ensembl4148,889,381 - 148,891,936 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147270   ⟹   ENSMUSP00000116095
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4148,985,606 - 149,017,353 (+)Ensembl
GRCm38.p6 Ensembl4148,901,149 - 148,932,896 (+)Ensembl
Ensembl Acc Id: ENSMUST00000239035   ⟹   ENSMUSP00000158908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4149,031,459 - 149,037,028 (+)Ensembl
GRCm38.p6 Ensembl4148,947,002 - 148,952,571 (+)Ensembl
RefSeq Acc Id: NM_001159344   ⟹   NP_001152816
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,888,849 - 149,039,349 (+)NCBI
GRCm384148,804,392 - 148,954,892 (+)NCBI
MGSCv374148,178,501 - 148,329,001 (+)RGD
Celera4151,067,937 - 151,218,394 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_027195   ⟹   NP_081471
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,888,849 - 149,029,587 (+)NCBI
GRCm384148,804,392 - 148,945,130 (+)NCBI
MGSCv374148,178,501 - 148,329,001 (+)RGD
Celera4151,067,937 - 151,218,394 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_161310
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,973,804 - 148,976,773 (+)NCBI
GRCm384148,889,347 - 148,892,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539157   ⟹   XP_006539220
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,985,143 - 149,039,350 (+)NCBI
GRCm384148,900,673 - 148,954,893 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539158   ⟹   XP_006539221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,888,823 - 149,039,350 (+)NCBI
GRCm384148,804,366 - 148,954,893 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539159   ⟹   XP_006539222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,888,972 - 149,039,350 (+)NCBI
GRCm384148,804,542 - 148,954,893 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539160   ⟹   XP_006539223
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394148,985,149 - 149,039,350 (+)NCBI
GRCm384148,900,676 - 148,954,893 (+)NCBI
Sequence:
RefSeq Acc Id: NP_081471   ⟸   NM_027195
- Peptide Label: isoform 2
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001152816   ⟸   NM_001159344
- Peptide Label: isoform 1
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot),   Q69Z25 (UniProtKB/Swiss-Prot),   A2A8A1 (UniProtKB/Swiss-Prot),   B1AS46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539221   ⟸   XM_006539158
- Peptide Label: isoform X2
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot),   Q69Z25 (UniProtKB/Swiss-Prot),   A2A8A1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539222   ⟸   XM_006539159
- Peptide Label: isoform X2
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot),   Q69Z25 (UniProtKB/Swiss-Prot),   A2A8A1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539220   ⟸   XM_006539157
- Peptide Label: isoform X1
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot),   Q69Z25 (UniProtKB/Swiss-Prot),   A2A8A1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539223   ⟸   XM_006539160
- Peptide Label: isoform X3
- UniProtKB: Q9CWL2 (UniProtKB/Swiss-Prot),   Q69Z25 (UniProtKB/Swiss-Prot),   A2A8A1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000120307   ⟸   ENSMUST00000139806
Ensembl Acc Id: ENSMUSP00000116095   ⟸   ENSMUST00000147270
Ensembl Acc Id: ENSMUSP00000158908   ⟸   ENSMUST00000239035
Ensembl Acc Id: ENSMUSP00000092035   ⟸   ENSMUST00000094464
Ensembl Acc Id: ENSMUSP00000112978   ⟸   ENSMUST00000122222
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CWL2-F1-model_v2 AlphaFold Q9CWL2 1-1761 view protein structure

Promoters
RGD ID:6835008
Promoter ID:MM_KWN:40837
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:NM_001159344,   NM_027195,   OTTMUST00000070196,   UC008VVK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364148,178,311 - 148,178,811 (+)MPROMDB
RGD ID:6885536
Promoter ID:EPDNEW_M6219
Type:initiation region
Name:Casz1_1
Description:Mus musculus castor zinc finger 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6220  EPDNEW_M6221  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384148,804,431 - 148,804,491EPDNEW
RGD ID:6885538
Promoter ID:EPDNEW_M6220
Type:multiple initiation site
Name:Casz1_2
Description:Mus musculus castor zinc finger 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6219  EPDNEW_M6221  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384148,828,378 - 148,828,438EPDNEW
RGD ID:6885540
Promoter ID:EPDNEW_M6221
Type:single initiation site
Name:Casz1_3
Description:Mus musculus castor zinc finger 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6219  EPDNEW_M6220  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384148,932,730 - 148,932,790EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196251 AgrOrtholog
Ensembl Genes ENSMUSG00000028977 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000094464 ENTREZGENE
  ENSMUST00000094464.10 UniProtKB/Swiss-Prot
  ENSMUST00000122222 ENTREZGENE
  ENSMUST00000122222.8 UniProtKB/TrEMBL
  ENSMUST00000139806.2 UniProtKB/TrEMBL
  ENSMUST00000147270.2 UniProtKB/TrEMBL
  ENSMUST00000239035.2 UniProtKB/TrEMBL
InterPro CASZ1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69743 UniProtKB/Swiss-Prot
MGD MGI:1196251 ENTREZGENE
NCBI Gene Casz1 ENTREZGENE
PANTHER PTHR12451 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER PROTEIN CASTOR HOMOLOG 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Casz1 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5F8MPC7_MOUSE UniProtKB/TrEMBL
  A2A8A1 ENTREZGENE
  B1AS46 ENTREZGENE, UniProtKB/TrEMBL
  B1AS47_MOUSE UniProtKB/TrEMBL
  B1AS48_MOUSE UniProtKB/TrEMBL
  CASZ1_MOUSE UniProtKB/Swiss-Prot
  Q3UTY4_MOUSE UniProtKB/TrEMBL
  Q69Z25 ENTREZGENE
  Q8BWG3_MOUSE UniProtKB/TrEMBL
  Q8CI82_MOUSE UniProtKB/TrEMBL
  Q9CWL2 ENTREZGENE
UniProt Secondary A2A8A1 UniProtKB/Swiss-Prot
  Q69Z25 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Casz1  castor zinc finger 1  D4Ertd432e  DNA segment, Chr 4, ERATO Doi 432, expressed  Symbol and/or name change 5135510 APPROVED
2024-08-21 D4Ertd432e  DNA segment, Chr 4, ERATO Doi 432, expressed  Casz1  castor zinc finger 1  Symbol and/or name change 5135510 APPROVED
2016-04-08 Casz1  castor zinc finger 1  BC035954  cDNA sequence BC035954  Data merged from RGD:1322710 737654 PROVISIONAL
2012-07-10 Casz1  castor zinc finger 1  Casz1  castor homolog 1, zinc finger (Drosophila)  Symbol and/or name change 5135510 APPROVED