SMARCA1 (SNF2 related chromatin remodeling ATPase 1) - Rat Genome Database

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Gene: SMARCA1 (SNF2 related chromatin remodeling ATPase 1) Chlorocebus sabaeus
Analyze
Symbol: SMARCA1
Name: SNF2 related chromatin remodeling ATPase 1 (Ensembl:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1)
RGD ID: 18417052
Description: ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); ATP-dependent chromatin remodeler activity (ortholog); ATP-dependent DNA/DNA annealing activity (ortholog); INVOLVED IN brain development (ortholog); neuron differentiation (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN ISWI family mediated chromatin remodeling pathway; ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); factor VIII deficiency (ortholog); FOUND IN ATPase complex (ortholog); CERF complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable global transcription activator SNF2L1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX104,690,689 - 104,768,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606542,175,535 - 42,253,073 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SMARCA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX104,690,689 - 104,768,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606542,175,535 - 42,253,073 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SMARCA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X129,446,506 - 129,523,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX129,446,501 - 129,523,500 (-)EnsemblGRCh38hg38GRCh38
GRCh37X128,580,483 - 128,657,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X128,408,159 - 128,485,122 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X128,306,012 - 128,382,976NCBI
CeleraX128,969,174 - 129,046,159 (-)NCBICelera
Cytogenetic MapXq25-q26.1NCBI
HuRefX117,987,239 - 118,059,634 (-)NCBIHuRef
CHM1_1X128,491,871 - 128,568,824 (-)NCBICHM1_1
T2T-CHM13v2.0X127,765,288 - 127,842,272 (-)NCBIT2T-CHM13v2.0
Smarca1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X46,898,247 - 46,981,490 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX46,898,245 - 46,981,851 (-)EnsemblGRCm39 Ensembl
GRCm38X47,809,370 - 47,892,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX47,809,368 - 47,892,974 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X45,162,547 - 45,245,729 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X44,053,997 - 44,137,146 (-)NCBIMGSCv36mm8
CeleraX35,318,277 - 35,394,449 (-)NCBICelera
Cytogenetic MapXA4NCBI
cM MapX25.41NCBI
Smarca1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X131,858,148 - 131,944,639 (-)NCBIGRCr8
mRatBN7.2X126,980,201 - 127,066,385 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX126,994,947 - 127,066,347 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,115,075 - 129,192,859 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X132,685,491 - 132,763,196 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X130,212,211 - 130,289,995 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X134,634,651 - 134,719,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX134,647,703 - 134,719,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X134,707,434 - 134,791,566 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,177,345 - 134,249,029 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX125,946,308 - 126,012,001 (-)NCBICelera
Cytogenetic MapXq35NCBI
Smarca1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554735,498,674 - 5,573,169 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554735,498,738 - 5,572,863 (+)NCBIChiLan1.0ChiLan1.0
SMARCA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X128,870,571 - 128,949,739 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X128,874,185 - 128,951,225 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X118,577,295 - 118,654,326 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X128,875,334 - 128,952,204 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX128,875,334 - 128,952,900 (-)Ensemblpanpan1.1panPan2
SMARCA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X100,678,457 - 100,749,216 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX100,679,942 - 100,749,651 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX86,845,498 - 86,918,086 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X102,524,025 - 102,596,588 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX102,524,025 - 102,596,704 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X99,941,623 - 100,014,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X101,786,630 - 101,859,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X101,565,278 - 101,638,177 (-)NCBIUU_Cfam_GSD_1.0
Smarca1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X98,876,999 - 98,956,698 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364792,030,716 - 2,110,661 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364792,030,788 - 2,110,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMARCA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX106,039,969 - 106,116,139 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X106,039,961 - 106,116,156 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X121,756,253 - 121,832,168 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Smarca1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247978,626,742 - 8,710,845 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247978,627,048 - 8,710,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000006510   ⟹   ENSCSAP00000004716
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX104,690,689 - 104,768,298 (-)Ensembl
RefSeq Acc Id: XM_007992643   ⟹   XP_007990834
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,535 - 42,253,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007992644   ⟹   XP_007990835
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,792 - 42,253,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007992645   ⟹   XP_007990836
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,792 - 42,253,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007992646   ⟹   XP_007990837
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,691,636 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,535 - 42,252,953 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007992647   ⟹   XP_007990838
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,792 - 42,253,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007992648   ⟹   XP_007990839
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X104,690,937 - 104,768,326 (-)NCBI
Vero_WHO_p1.0NW_02366606542,175,792 - 42,253,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037989115   ⟹   XP_037845043
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606542,175,790 - 42,253,073 (-)NCBI
RefSeq Acc Id: XM_037989116   ⟹   XP_037845044
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606542,175,792 - 42,253,073 (-)NCBI
RefSeq Acc Id: XP_007990835   ⟸   XM_007992644
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R7X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990839   ⟸   XM_007992648
- Peptide Label: isoform X5
RefSeq Acc Id: XP_007990834   ⟸   XM_007992643
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007990838   ⟸   XM_007992647
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007990836   ⟸   XM_007992645
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007990837   ⟸   XM_007992646
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCSAP00000004716   ⟸   ENSCSAT00000006510
RefSeq Acc Id: XP_037845043   ⟸   XM_037989115
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037845044   ⟸   XM_037989116
- Peptide Label: isoform X6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008460 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006510.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1040.30 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  iswi atpase UniProtKB/TrEMBL
InterPro Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  ISWI_HAND-dom UniProtKB/TrEMBL
  ISWI_HAND-dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_dom UniProtKB/TrEMBL
  SLIDE UniProtKB/TrEMBL
  SMARCA1_N UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
NCBI Gene SMARCA1 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED UniProtKB/TrEMBL
  ISW-1 UniProtKB/TrEMBL
Pfam HAND UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SLIDE UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF101224 UniProtKB/TrEMBL
  SSF46689 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9R7X7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 SMARCA1  SNF2 related chromatin remodeling ATPase 1  SMARCA1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1  Symbol and/or name change 5135510 APPROVED