FOXA3 (forkhead box A3) - Rat Genome Database

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Gene: FOXA3 (forkhead box A3) Chlorocebus sabaeus
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Symbol: FOXA3
Name: forkhead box A3
RGD ID: 18766211
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); intracellular glucose homeostasis (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Prostatic Neoplasms (ortholog); FOUND IN actin cytoskeleton (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hepatocyte nuclear factor 3-gamma
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,309,439 - 39,320,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,310,108 - 39,320,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,951,536 - 18,962,292 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FOXA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,309,439 - 39,320,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,310,108 - 39,320,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,951,536 - 18,962,292 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FOXA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,864,326 - 45,873,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,863,989 - 45,873,797 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,367,584 - 46,377,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,059,358 - 51,068,895 (+)NCBINCBI36Build 36hg18NCBI36
Celera1943,172,554 - 43,182,091 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,796,032 - 42,805,584 (+)NCBIHuRef
CHM1_11946,369,977 - 46,379,501 (+)NCBICHM1_1
T2T-CHM13v2.01948,691,764 - 48,701,238 (+)NCBIT2T-CHM13v2.0
Foxa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,747,208 - 18,757,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,747,209 - 18,757,463 (-)EnsemblGRCm39 Ensembl
GRCm38719,013,283 - 19,023,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,013,284 - 19,023,538 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,598,632 - 19,608,888 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,171,805 - 18,182,061 (-)NCBIMGSCv36mm8
Celera716,424,993 - 16,435,230 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Foxa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,790,111 - 87,800,259 (-)NCBIGRCr8
mRatBN7.2178,662,067 - 78,672,321 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,662,431 - 78,672,155 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,051,578 - 84,060,504 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,609,178 - 92,618,101 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,806,680 - 85,815,606 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,921,292 - 79,930,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,920,752 - 79,930,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,181,104 - 81,190,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,368,026 - 78,376,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,446,136 - 78,455,064 (-)NCBI
Celera173,128,615 - 73,137,542 (-)NCBICelera
Cytogenetic Map1q21NCBI
Foxa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574293,344 - 302,002 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955574293,344 - 301,955 (+)NCBIChiLan1.0ChiLan1.0
FOXA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,029,299 - 52,039,689 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,900,693 - 53,911,081 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,873,933 - 42,883,479 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,410,294 - 51,419,483 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,410,473 - 51,418,744 (+)Ensemblpanpan1.1panPan2
FOXA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,749,142 - 109,757,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,748,926 - 109,757,006 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,234,450 - 109,242,454 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,281,914 - 110,289,921 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,281,781 - 110,290,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,957,939 - 109,965,942 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,592,626 - 109,600,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,461,391 - 110,469,396 (-)NCBIUU_Cfam_GSD_1.0
Foxa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,849,096 - 17,856,150 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,196,468 - 2,203,113 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,196,530 - 2,202,924 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,181,114 - 52,188,774 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,181,095 - 52,188,777 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,444,473 - 47,452,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Foxa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,338,478 - 7,350,658 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,339,612 - 7,350,651 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
30 21 17 30 30 17 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007997263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000001139   ⟹   ENSCSAP00000014931
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl639,310,108 - 39,320,095 (+)Ensembl
RefSeq Acc Id: XM_007997263   ⟹   XP_007995454
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1639,309,439 - 39,320,102 (+)NCBI
Vero_WHO_p1.0NW_02366607318,951,536 - 18,962,292 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995454 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014931
  ENSCSAP00000014931.1
RefSeq Acc Id: XP_007995454   ⟸   XM_007997263
- UniProtKB: A0A0D9S242 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000014931   ⟸   ENSCSAT00000001139


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003110 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001139.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXA3 UniProtKB/TrEMBL
  Fork-head_N UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOX_domain-containing UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene FOXA3 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN UniProtKB/TrEMBL
  HEPATOCYTE NUCLEAR FACTOR 3-GAMMA UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
  Forkhead_N UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A0D9S242 ENTREZGENE, UniProtKB/TrEMBL