Foxa3 (forkhead box A3) - Rat Genome Database

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Gene: Foxa3 (forkhead box A3) Heterocephalus glaber
Analyze
Symbol: Foxa3
Name: forkhead box A3
RGD ID: 18914784
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); intracellular glucose homeostasis (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Prostatic Neoplasms (ortholog); FOUND IN actin cytoskeleton (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Hepatocyte nuclear factor 3-gamma
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,338,478 - 7,350,658 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,339,612 - 7,350,651 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Foxa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,338,478 - 7,350,658 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,339,612 - 7,350,651 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FOXA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,864,326 - 45,873,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,863,989 - 45,873,797 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,367,584 - 46,377,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,059,358 - 51,068,895 (+)NCBINCBI36Build 36hg18NCBI36
Celera1943,172,554 - 43,182,091 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,796,032 - 42,805,584 (+)NCBIHuRef
CHM1_11946,369,977 - 46,379,501 (+)NCBICHM1_1
T2T-CHM13v2.01948,691,764 - 48,701,238 (+)NCBIT2T-CHM13v2.0
Foxa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,747,208 - 18,757,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,747,209 - 18,757,463 (-)EnsemblGRCm39 Ensembl
GRCm38719,013,283 - 19,023,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,013,284 - 19,023,538 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,598,632 - 19,608,888 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,171,805 - 18,182,061 (-)NCBIMGSCv36mm8
Celera716,424,993 - 16,435,230 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Foxa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,790,111 - 87,800,259 (-)NCBIGRCr8
mRatBN7.2178,662,067 - 78,672,321 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,662,431 - 78,672,155 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,051,578 - 84,060,504 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,609,178 - 92,618,101 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,806,680 - 85,815,606 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,921,292 - 79,930,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,920,752 - 79,930,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,181,104 - 81,190,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,368,026 - 78,376,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,446,136 - 78,455,064 (-)NCBI
Celera173,128,615 - 73,137,542 (-)NCBICelera
Cytogenetic Map1q21NCBI
Foxa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574293,344 - 302,002 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955574293,344 - 301,955 (+)NCBIChiLan1.0ChiLan1.0
FOXA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,029,299 - 52,039,689 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,900,693 - 53,911,081 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,873,933 - 42,883,479 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,410,294 - 51,419,483 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,410,473 - 51,418,744 (+)Ensemblpanpan1.1panPan2
FOXA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,749,142 - 109,757,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,748,926 - 109,757,006 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,234,450 - 109,242,454 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,281,914 - 110,289,921 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,281,781 - 110,290,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,957,939 - 109,965,942 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,592,626 - 109,600,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,461,391 - 110,469,396 (-)NCBIUU_Cfam_GSD_1.0
Foxa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,849,096 - 17,856,150 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,196,468 - 2,203,113 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,196,530 - 2,202,924 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,181,114 - 52,188,774 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,181,095 - 52,188,777 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,444,473 - 47,452,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,309,439 - 39,320,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,310,108 - 39,320,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,951,536 - 18,962,292 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027454   ⟹   ENSHGLP00000027213
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248327,338,478 - 7,350,658 (-)Ensembl
RefSeq Acc Id: XM_004867126   ⟹   XP_004867183
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248327,339,612 - 7,350,651 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004867183 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB00844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027213
  ENSHGLP00100043794
GenBank Protein JAO00194 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004867183   ⟸   XM_004867126
- UniProtKB: G5AUY3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027213   ⟸   ENSHGLT00000027454


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019353 Ensembl, ENTREZGENE
  ENSHGLG00100037259 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027454 ENTREZGENE
  ENSHGLT00100073969 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXA3 UniProtKB/TrEMBL
  Fork-head_N UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOX_domain-containing UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report hgl:101702061 UniProtKB/TrEMBL
NCBI Gene Foxa3 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN UniProtKB/TrEMBL
  HEPATOCYTE NUCLEAR FACTOR 3-GAMMA UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
  Forkhead_N UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt G5AUY3 ENTREZGENE, UniProtKB/TrEMBL