PSCA (prostate stem cell antigen)

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Gene: PSCA (prostate stem cell antigen) Chlorocebus sabaeus

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Symbol:

PSCA

Name:

prostate stem cell antigen

RGD ID:

18552906

Description:

ENCODES a protein that exhibits acetylcholine receptor binding (inferred); INVOLVED IN regulation of neurotransmitter receptor activity (ortholog); ASSOCIATED WITH duodenal ulcer (ortholog); Helicobacter Infections (ortholog); linitis plastica (ortholog); FOUND IN plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	136,925,881 - 136,929,257 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666039	3,025,823 - 3,028,932 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

duodenal ulcer (ISO)

Helicobacter Infections (ISO)

linitis plastica (ISO)

pre-malignant neoplasm (ISO)

Prostatic Neoplasms (ISO)

Stomach Neoplasms (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of ERK1 and ERK2 cascade (IEA)

regulation of neurotransmitter receptor activity (ISO)

Cellular Component

plasma membrane (IEA)

Molecular Function

acetylcholine receptor binding (IEA)

References

Genomics

Comparative Map Data

PSCA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	136,925,881 - 136,929,257 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666039	3,025,823 - 3,028,932 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PSCA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	142,670,297 - 142,682,725 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	142,670,308 - 142,682,725 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	143,751,715 - 143,764,143 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	143,758,877 - 143,761,145 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	143,758,914 - 143,761,107	NCBI
Celera	8	140,062,953 - 140,075,307 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	NCBI
HuRef	8	139,004,448 - 139,016,803 (+)	NCBI		HuRef
CHM1_1	8	143,791,995 - 143,804,414 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	143,813,825 - 143,826,193 (+)	NCBI		T2T-CHM13v2.0

Psca
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	74,586,688 - 74,588,914 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	74,586,688 - 74,588,918 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	74,714,839 - 74,717,065 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	74,714,839 - 74,717,069 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	74,545,269 - 74,547,495 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	74,542,094 - 74,544,324 (+)	NCBI		MGSCv36	mm8
Celera	15	76,219,780 - 76,222,006 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	34.26	NCBI

Psca
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	108,483,974 - 108,492,098 (+)	NCBI		GRCr8
mRatBN7.2	7	106,598,203 - 106,603,114 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	106,595,284 - 106,609,746 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	116,090,189 - 116,091,955 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	116,090,189 - 116,091,955 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	115,995,492 - 115,997,258 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	7	115,857,434 - 115,858,209 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	112,823,862 - 112,835,190 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	103,002,175 - 103,003,865 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

Psca
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	1,425,255 - 1,429,786 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	1,425,255 - 1,429,786 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSCA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	160,116,213 - 160,118,993 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	135,641,454 - 135,645,203 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	139,384,002 - 139,394,993 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	142,435,849 - 142,438,401 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	142,435,849 - 142,438,401 (+)	Ensembl	panpan1.1		panPan2

PSCA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	36,773,434 - 36,776,740 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	36,773,875 - 36,776,194 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	36,649,736 - 36,652,787 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	37,177,153 - 37,180,204 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	37,177,339 - 37,180,204 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	36,895,880 - 36,898,931 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	36,985,523 - 36,988,575 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	37,407,594 - 37,410,646 (+)	NCBI		UU_Cfam_GSD_1.0

Psca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	1,716,908 - 1,719,360 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	9,142,327 - 9,145,722 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	9,143,003 - 9,145,438 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSCA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	1,479,879 - 1,482,354 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	1,479,872 - 1,484,245 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Psca
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	13,918,508 - 13,920,881 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	13,918,508 - 13,920,888 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008001680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_008001680 ⟹ XP_007999871

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	8	136,925,881 - 136,929,257 (+)	NCBI
Vero_WHO_p1.0	NW_023666039	3,025,823 - 3,028,932 (-)	NCBI

Sequence:

show sequence

GAGAGGAGGGGTCCACTCAGATGGCTGGGGGTCCTTAGAATGTTACTTTTGGTTCACACCCGGA
ATAGCCCCTGCCCCTCTCCTTTGCAGCACCTGCTGCTGATCTGTCAGTGACGCTGTGACCAAGA
CTTATCACCCCGTGGGCCGTGGGCCGTGGGCCCCAGGAGGGCGGCACAGCTTCTGTAGGAGCAC
AGGGCCCAGGGAGGTGCCCTCGTCCTTGGTTGGAAGGCCGAGGCCTGGAGGAGTCTGGAGAAAG
GGTCTCCCTTGTCTGGCCTTGCGCTGTGAGGTTGGGGAGGTGGGAGAGGCATAATCTGGGGCCT
GAGGACATTTCAGCCCTCAGCCCGGGGTGGCTGAGATATGGCCCTGGGCAGGCTCTGTCCTTCA
GAGGTGGAAAGAAGGACAAAGGGAGAGGGAGGTGCAGGTCACTCAGGGAGGAGACTCAGATCTG
CCCAGTCCCGGGGCCCTCACTGGCTCCAGGAAACCCGCTAGTGTTGACTGTGGGCAGTCCAGCC
TCTCCCCAGCTGCGGTCATATAAAGCCACTCAGGGCCCTCTCCACCGCTGCCCACCCGTGACCA
TGAAGGCTGTGCTGCTTGCCCTGTTGATGGCAGGCTTGGCCCTGCAGCCAGGCACTGCCCTGCT
GTGCTACTCCTGCAAGGCCCAGGTGAGCAACGAGGACTGCCTGAATGTGGAGAACTGCACGCAG
CCGGAGGAGCAGTGCTGGACCGAGCGCATCCGCGCCGTGGGCCTCCTGACCGTCATCAGCAAAG
GCTGCAGCTCAAACTGCGTGGATGACTCACAGGACTACTACGTGGGCAAGAAGAACATCACCTG
CTGTGACACCGACTTGTGCAACGCCAGCGGGGCCCATGCCCTGCAGCCGGCTGCCGCCATCCTG
GCGCTGCTCCCTGCACTCAGCCTGCTGCTTTGGGGCCCCAGACAGCTGTAGGCTTCCGGGGGCC
CTGCTGCAGCCCACACTGGGTGTGGTGCCCCAGGTCCCCGTGCCACTCCTCACACACCCGGCCC
AGTGGGAGCCTGTCCTGGTTCCTGAGGCACGTCCTAACACAGGTCTGACCATGTCCCTCTGCAC
CTCTGCCCTCCACCCTGACCCTCCCATGGCCCTCTCCAGGACTCCCACCCGGCAGATCGGCTCT
AGTGACACAGATCGGCCTGCAGACGGCCCCTCCAACCCTCTCTGCTGCTGTTTCCATGGCCCAG
CATTCTCCACCCTTAACGCTGTGCTCAGGCACCTCTTCCTCCAGGAAGCCTTCCCTGCCTACCC
CATCTATGACCTGAGCCAGGTCTGGTCCATGGTGTCCCCCACACCCAGCAGGGGACAGGCACTC
AGGAGGGCCCAGCAAAGGCTGAGATGAAGTGGACTGGGTAGAACTGGAGGACGGGGGTAGCATG
AGTTCCTGGGAGGCTCCAGAGATGGGGCCTGGAGGCCTGAAGGGAGGGGCCAGGCCTCACATTC
ATGGGGCTTCCTGAACGGCAGCCTCAGCACAGCGTAGGCCCTTAATAAACACCTGTTGAATAAG
CCAGA

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Protein Sequences


Protein RefSeqs	XP_007999871	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000005511.1

RefSeq Acc Id:	XP_007999871 ⟸ XM_008001680
- UniProtKB:	A0A0D9RA72 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009257	UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007324.1	UniProtKB/TrEMBL
Gene3D-CATH	CD59	UniProtKB/TrEMBL
InterPro	Ly-6/neurotoxin-like_GPI-ap	UniProtKB/TrEMBL
	LY6_UPA_recep-like	UniProtKB/TrEMBL
	Snake_toxin-like_sf	UniProtKB/TrEMBL
NCBI Gene	PSCA	ENTREZGENE
PANTHER	PROSTATE STEM CELL ANTIGEN	UniProtKB/TrEMBL
	UPAR/LY6 DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	UPAR_LY6	UniProtKB/TrEMBL
SMART	SM00134	UniProtKB/TrEMBL
Superfamily-SCOP	Snake toxin-like	UniProtKB/TrEMBL
UniProt	A0A0D9RA72	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD