MX1 (MX dynamin like GTPase 1) - Rat Genome Database

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Gene: MX1 (MX dynamin like GTPase 1) Chlorocebus sabaeus
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Symbol: MX1
Name: MX dynamin like GTPase 1
RGD ID: 18646638
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); identical protein binding (inferred); INVOLVED IN cellular response to type I interferon (ortholog); endosomal transport (ortholog); negative regulation of intracellular transport of viral material (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); alopecia areata (ortholog); Animal Disease Models (ortholog); FOUND IN exocytic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interferon-induced GTP-binding protein Mx1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,333,327 - 85,368,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,338,530 - 85,368,507 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605413,185,843 - 13,220,898 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,333,327 - 85,368,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,338,530 - 85,368,507 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605413,185,843 - 13,220,898 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382141,420,558 - 41,459,214 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2141,420,020 - 41,470,071 (+)EnsemblGRCh38hg38GRCh38
GRCh372142,792,485 - 42,831,141 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,720,024 - 41,753,008 (+)NCBINCBI36Build 36hg18NCBI36
Build 342141,720,023 - 41,753,008NCBI
Celera2127,990,716 - 28,029,320 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2128,261,373 - 28,300,013 (+)NCBIHuRef
CHM1_12142,353,308 - 42,391,928 (+)NCBICHM1_1
T2T-CHM13v2.02139,807,998 - 39,847,898 (+)NCBIT2T-CHM13v2.0
Mx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,337,281 - 97,362,101 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1697,336,508 - 97,362,100 (+)EnsemblGRCm39 Ensembl
GRCm381697,536,081 - 97,560,901 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,535,308 - 97,560,900 (+)EnsemblGRCm38mm10GRCm38
MGSCv371697,757,688 - 97,782,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361697,690,999 - 97,715,815 (+)NCBIMGSCv36mm8
Celera1698,596,943 - 98,621,730 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.51NCBI
Mx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,375,101 - 50,399,373 (+)NCBIGRCr8
mRatBN7.21136,905,698 - 36,936,308 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,906,111 - 36,930,342 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,604,887 - 45,630,454 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,276,267 - 38,301,834 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,436,195 - 37,461,762 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,035,306 - 38,066,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,035,450 - 38,059,950 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,545,958 - 41,570,577 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,548,650 - 37,572,717 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,608,291 - 37,630,303 (+)NCBI
Celera1136,790,647 - 36,814,700 (+)NCBICelera
RH 3.4 Map11263.01RGD
Cytogenetic Map11q12NCBI
MX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22237,503,227 - 37,541,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12132,357,510 - 32,396,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02127,756,768 - 27,795,307 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,089,711 - 41,123,019 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,095,928 - 41,123,019 (+)Ensemblpanpan1.1panPan2
MX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13135,898,206 - 35,929,802 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3135,860,590 - 35,951,350 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,060,087 - 35,084,645 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03135,419,440 - 35,447,820 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3135,367,708 - 35,468,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13135,318,427 - 35,342,955 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03135,297,561 - 35,322,100 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03135,791,284 - 35,815,851 (+)NCBIUU_Cfam_GSD_1.0
MX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13204,843,754 - 204,868,922 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113204,843,049 - 204,868,927 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213214,988,890 - 215,014,780 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000006289   ⟹   ENSCSAP00000004496
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl285,338,530 - 85,368,507 (+)Ensembl
RefSeq Acc Id: XM_007968690   ⟹   XP_007966881
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1285,333,327 - 85,368,179 (+)NCBI
Vero_WHO_p1.0NW_02366605413,185,898 - 13,220,898 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968698   ⟹   XP_007966889
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1285,333,421 - 85,368,179 (+)NCBI
Vero_WHO_p1.0NW_02366605413,185,992 - 13,220,898 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968708   ⟹   XP_007966899
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1285,333,579 - 85,368,179 (+)NCBI
Vero_WHO_p1.0NW_02366605413,186,135 - 13,220,898 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968715   ⟹   XP_007966906
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1285,333,327 - 85,368,179 (+)NCBI
Vero_WHO_p1.0NW_02366605413,185,898 - 13,220,898 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037984843   ⟹   XP_037840771
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605413,185,843 - 13,220,898 (+)NCBI
RefSeq Acc Id: XM_037984844   ⟹   XP_037840772
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605413,185,898 - 13,220,898 (+)NCBI
RefSeq Acc Id: XP_007966881   ⟸   XM_007968690
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966906   ⟸   XM_007968715
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966889   ⟸   XM_007968698
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966899   ⟸   XM_007968708
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000004496   ⟸   ENSCSAT00000006289
RefSeq Acc Id: XP_037840771   ⟸   XM_037984843
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037840772   ⟸   XM_037984844
- UniProtKB: A0A0D9R7A7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008237 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006289.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  Dynamin, middle domain UniProtKB/TrEMBL
InterPro Dynamin_central UniProtKB/TrEMBL
  Dynamin_GTPase UniProtKB/TrEMBL
  Dynamin_GTPase_CS UniProtKB/TrEMBL
  Dynamin_N UniProtKB/TrEMBL
  Dynamin_SF UniProtKB/TrEMBL
  G_DYNAMIN_dom UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
  GED_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report csab:103219174 UniProtKB/TrEMBL
NCBI Gene MX1 ENTREZGENE
PANTHER INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 UniProtKB/TrEMBL
  PTHR11566 UniProtKB/TrEMBL
Pfam Dynamin_M UniProtKB/TrEMBL
  Dynamin_N UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
PRINTS DYNAMIN UniProtKB/TrEMBL
PROSITE G_DYNAMIN_1 UniProtKB/TrEMBL
  G_DYNAMIN_2 UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
SMART DYNc UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9R7A7 ENTREZGENE, UniProtKB/TrEMBL