UNC13D (unc-13 homolog D) - Rat Genome Database

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Gene: UNC13D (unc-13 homolog D) Chlorocebus sabaeus
Analyze
Symbol: UNC13D
Name: unc-13 homolog D
RGD ID: 18572015
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN defense response to virus (ortholog); dense core granule priming (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH Chediak-Higashi syndrome (ortholog); Familial Hemophagocytic Lymphohistiocytoses (ortholog); familial hemophagocytic lymphohistiocytosis 3 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein unc-13 homolog D
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,836,659 - 45,856,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,838,175 - 45,857,201 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,591,807 - 16,612,493 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
UNC13D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,836,659 - 45,856,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,838,175 - 45,857,201 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,591,807 - 16,612,493 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UNC13D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,827,225 - 75,844,404 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,827,225 - 75,844,785 (-)EnsemblGRCh38hg38GRCh38
GRCh371773,823,306 - 73,840,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,334,901 - 71,352,393 (-)NCBINCBI36Build 36hg18NCBI36
Celera1770,413,355 - 70,430,847 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,249,056 - 69,266,442 (-)NCBIHuRef
CHM1_11773,888,239 - 73,905,757 (-)NCBICHM1_1
T2T-CHM13v2.01776,720,377 - 76,737,555 (-)NCBIT2T-CHM13v2.0
Unc13d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,952,921 - 115,969,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,952,921 - 115,968,787 (-)EnsemblGRCm39 Ensembl
GRCm3811116,062,095 - 116,078,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,062,095 - 116,077,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,923,410 - 115,939,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,878,186 - 115,894,051 (-)NCBIMGSCv36mm8
Celera11127,824,298 - 127,840,219 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Unc13d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,795,652 - 101,810,409 (-)NCBIGRCr8
mRatBN7.210101,296,755 - 101,311,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,296,776 - 101,311,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,358,330 - 106,372,954 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,821,421 - 105,836,045 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,217,675 - 101,232,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,613,907 - 104,628,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,613,928 - 104,628,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,656,707 - 103,671,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,170,475 - 106,185,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,184,978 - 106,199,719 (-)NCBI
Celera1099,870,790 - 99,885,526 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Unc13d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,407,723 - 6,423,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,407,073 - 6,423,406 (+)NCBIChiLan1.0ChiLan1.0
UNC13D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,871,152 - 91,889,518 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,695,680 - 96,714,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,777,570 - 69,794,877 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,327,849 - 75,345,282 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,328,572 - 75,344,842 (-)Ensemblpanpan1.1panPan2
UNC13D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,753,300 - 4,766,751 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,753,166 - 4,766,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,433,452 - 5,446,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,423,494 - 5,436,930 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,423,348 - 5,436,929 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,463,219 - 5,476,653 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,573,315 - 5,586,743 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,633,988 - 5,647,426 (+)NCBIUU_Cfam_GSD_1.0
Unc13d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,388,869 - 5,403,744 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,008,327 - 1,021,878 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,008,215 - 1,023,023 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,573,668 - 5,589,085 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,573,428 - 5,598,914 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,520,083 - 5,535,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Unc13d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,721,391 - 5,736,294 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,720,998 - 5,736,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000002915   ⟹   ENSCSAP00000001199
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1645,838,175 - 45,857,201 (+)Ensembl
RefSeq Acc Id: XM_008011721   ⟹   XP_008009912
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11645,836,659 - 45,856,805 (+)NCBI
Vero_WHO_p1.0NW_02366607716,593,120 - 16,612,493 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037993460   ⟹   XP_037849388
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607716,591,807 - 16,612,493 (+)NCBI
RefSeq Acc Id: XM_037993461   ⟹   XP_037849389
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607716,593,258 - 16,612,493 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008009912 (Get FASTA)   NCBI Sequence Viewer  
  XP_037849388 (Get FASTA)   NCBI Sequence Viewer  
  XP_037849389 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001199.1
RefSeq Acc Id: XP_008009912   ⟸   XM_008011721
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QXW0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001199   ⟸   ENSCSAT00000002915
RefSeq Acc Id: XP_037849388   ⟸   XM_037993460
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QXW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037849389   ⟸   XM_037993461
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QXW0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004874 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002915.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  1.20.58.1100 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  MUN_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  UNC-13_domain UniProtKB/TrEMBL
NCBI Gene UNC13D ENTREZGENE
PANTHER PROTEIN UNC-13 HOMOLOG D UniProtKB/TrEMBL
  UNC-13-4A, ISOFORM B UniProtKB/TrEMBL
Pfam MUN UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A0D9QXW0 ENTREZGENE, UniProtKB/TrEMBL