Unc13d (unc-13 homolog D) - Rat Genome Database

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Gene: Unc13d (unc-13 homolog D) Chinchilla lanigera
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Symbol: Unc13d
Name: unc-13 homolog D
RGD ID: 8915419
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN defense response to virus (ortholog); dense core granule priming (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH Chediak-Higashi syndrome (ortholog); Familial Hemophagocytic Lymphohistiocytoses (ortholog); familial hemophagocytic lymphohistiocytosis 3 (ortholog); FOUND IN cytosol (ortholog); exocytic vesicle (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unc-13 homolog D (C. elegans)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,407,723 - 6,423,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,407,073 - 6,423,406 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Unc13d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,407,723 - 6,423,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,407,073 - 6,423,406 (+)NCBIChiLan1.0ChiLan1.0
UNC13D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,827,225 - 75,844,404 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,827,225 - 75,844,785 (-)EnsemblGRCh38hg38GRCh38
GRCh371773,823,306 - 73,840,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,334,901 - 71,352,393 (-)NCBINCBI36Build 36hg18NCBI36
Celera1770,413,355 - 70,430,847 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,249,056 - 69,266,442 (-)NCBIHuRef
CHM1_11773,888,239 - 73,905,757 (-)NCBICHM1_1
T2T-CHM13v2.01776,720,377 - 76,737,555 (-)NCBIT2T-CHM13v2.0
Unc13d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,952,921 - 115,969,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,952,921 - 115,968,787 (-)EnsemblGRCm39 Ensembl
GRCm3811116,062,095 - 116,078,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,062,095 - 116,077,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,923,410 - 115,939,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,878,186 - 115,894,051 (-)NCBIMGSCv36mm8
Celera11127,824,298 - 127,840,219 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Unc13d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,795,652 - 101,810,409 (-)NCBIGRCr8
mRatBN7.210101,296,755 - 101,311,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,296,776 - 101,311,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,358,330 - 106,372,954 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,821,421 - 105,836,045 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,217,675 - 101,232,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,613,907 - 104,628,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,613,928 - 104,628,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,656,707 - 103,671,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,170,475 - 106,185,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,184,978 - 106,199,719 (-)NCBI
Celera1099,870,790 - 99,885,526 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
UNC13D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,871,152 - 91,889,518 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,695,680 - 96,714,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,777,570 - 69,794,877 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,327,849 - 75,345,282 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,328,572 - 75,344,842 (-)Ensemblpanpan1.1panPan2
UNC13D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,753,300 - 4,766,751 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,753,166 - 4,766,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,433,452 - 5,446,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,423,494 - 5,436,930 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,423,348 - 5,436,929 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,463,219 - 5,476,653 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,573,315 - 5,586,743 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,633,988 - 5,647,426 (+)NCBIUU_Cfam_GSD_1.0
Unc13d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,388,869 - 5,403,744 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,008,327 - 1,021,878 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,008,215 - 1,023,023 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,573,668 - 5,589,085 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,573,428 - 5,598,914 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,520,083 - 5,535,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC13D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,836,659 - 45,856,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,838,175 - 45,857,201 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,591,807 - 16,612,493 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc13d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,721,391 - 5,736,294 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,720,998 - 5,736,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000015853   ⟹   ENSCLAP00000015691
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555066,407,723 - 6,423,406 (+)Ensembl
RefSeq Acc Id: XM_005407474   ⟹   XP_005407531
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555066,407,723 - 6,423,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005407476   ⟹   XP_005407533
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555066,408,582 - 6,423,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013506052   ⟹   XP_013361506
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555066,407,073 - 6,423,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013506053   ⟹   XP_013361507
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555066,407,342 - 6,423,406 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407531 (Get FASTA)   NCBI Sequence Viewer  
  XP_005407533 (Get FASTA)   NCBI Sequence Viewer  
  XP_013361506 (Get FASTA)   NCBI Sequence Viewer  
  XP_013361507 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015691
  ENSCLAP00000015691.1
RefSeq Acc Id: XP_005407531   ⟸   XM_005407474
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VP90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005407533   ⟸   XM_005407476
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013361506   ⟸   XM_013506052
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013361507   ⟸   XM_013506053
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000015691   ⟸   ENSCLAT00000015853
Protein Domains
C2   MHD1   MHD2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010782 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015853 ENTREZGENE
  ENSCLAT00000015853.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  1.20.58.1100 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  MUN_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  UNC-13_domain UniProtKB/TrEMBL
NCBI Gene Unc13d ENTREZGENE
PANTHER PROTEIN UNC-13 HOMOLOG D UniProtKB/TrEMBL
  UNC-13-4A, ISOFORM B UniProtKB/TrEMBL
Pfam MUN UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2VP90 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Unc13d  unc-13 homolog D    unc-13 homolog D (C. elegans)  Symbol and/or name change 5135510 APPROVED