PDPK1 (3-phosphoinositide dependent protein kinase 1) - Rat Genome Database

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Gene: PDPK1 (3-phosphoinositide dependent protein kinase 1) Chlorocebus sabaeus
Analyze
Symbol: PDPK1
Name: 3-phosphoinositide dependent protein kinase 1
RGD ID: 18593685
Description: ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase activity (ortholog); insulin receptor binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); focal adhesion assembly (ortholog); hyperosmotic response (ortholog); PARTICIPATES IN adenosine signaling pathway; angiotensin II signaling pathway; FasL mediated signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); congestive heart failure (ortholog); diffuse large B-cell lymphoma (ortholog); FOUND IN cytoplasmic vesicle (ortholog); perikaryon (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-phosphoinositide-dependent protein kinase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606828,533,894 - 28,612,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606828,533,894 - 28,612,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PDPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,538,021 - 2,603,188 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,537,979 - 2,603,188 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,588,022 - 2,653,189 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,527,971 - 2,593,190 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,527,970 - 2,593,189NCBI
Cytogenetic Map16p13.3NCBI
HuRef162,533,939 - 2,579,217 (+)NCBIHuRef
CHM1_1162,587,908 - 2,653,167 (+)NCBICHM1_1
T2T-CHM13v2.0162,560,174 - 2,625,339 (+)NCBIT2T-CHM13v2.0
Pdpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,292,654 - 24,370,957 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,292,654 - 24,369,898 (-)EnsemblGRCm39 Ensembl
GRCm381724,073,680 - 24,155,619 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,073,680 - 24,150,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,210,647 - 24,278,561 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,806,503 - 23,869,181 (-)NCBIMGSCv36mm8
Celera1724,579,774 - 24,646,541 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.23NCBI
Pdpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,610,000 - 13,687,226 (-)NCBIGRCr8
mRatBN7.21013,105,435 - 13,182,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,105,498 - 13,174,623 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,855,532 - 17,919,448 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,344,364 - 17,408,286 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,842,927 - 12,906,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,446,373 - 13,525,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,451,624 - 13,515,448 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,262,177 - 13,339,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,329,708 - 13,394,080 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,329,707 - 13,394,080 (-)NCBI
Celera1012,796,598 - 12,860,647 (-)NCBICelera
Cytogenetic Map10q12NCBI
Pdpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,685,153 - 14,772,870 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,685,089 - 14,772,870 (-)NCBIChiLan1.0ChiLan1.0
PDPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,039,537 - 3,108,833 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,820,580 - 6,889,876 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,394,447 - 1,463,735 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PDPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,426,464 - 38,506,520 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,431,600 - 38,499,295 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,665,293 - 39,744,671 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,736,122 - 38,815,513 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,739,163 - 38,809,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,421,263 - 38,500,661 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,393,915 - 38,473,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,869,968 - 38,949,380 (-)NCBIUU_Cfam_GSD_1.0
Pdpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,173,175 - 105,264,644 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,526,653 - 1,537,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049366941,444,880 - 1,488,265 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,444,819 - 1,487,628 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,432,058 - 39,512,601 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,429,928 - 39,512,623 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,792,968 - 42,830,074 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pdpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824293,374 - 383,156 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824279,893 - 383,220 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_037989961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_037989961   ⟹   XP_037845889
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606828,533,894 - 28,612,865 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037845889 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014294.1
Reference Protein Sequences
RefSeq Acc Id: XP_037845889   ⟸   XM_037989961
- UniProtKB: A0A0D9S0A5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018281 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016377.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PDK1-typ_PH UniProtKB/TrEMBL
  PDPK1 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene PDPK1 ENTREZGENE
PANTHER 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam PH_3 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9S0A5 ENTREZGENE, UniProtKB/TrEMBL