NOX3 (NADPH oxidase 3) - Rat Genome Database

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Gene: NOX3 (NADPH oxidase 3) Chlorocebus sabaeus
Analyze
Symbol: NOX3
Name: NADPH oxidase 3
RGD ID: 18733563
Description: ENCODES a protein that exhibits heme binding (inferred); oxidoreductase activity (inferred); oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor (inferred); INVOLVED IN detection of gravity (ortholog); otolith development (ortholog); response to gravity (ortholog); PARTICIPATES IN thyroid hormone biosynthetic pathway; ASSOCIATED WITH chromosome 6q24-q25 deletion syndrome (ortholog); genetic disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); NADPH oxidase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11382,972,005 - 83,033,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1382,970,184 - 83,032,974 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604055,340,628 - 55,441,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NOX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11382,972,005 - 83,033,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1382,970,184 - 83,032,974 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604055,340,628 - 55,441,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NOX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386155,395,368 - 155,455,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6155,395,368 - 155,455,839 (-)EnsemblGRCh38hg38GRCh38
GRCh376155,716,502 - 155,776,973 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366155,758,194 - 155,818,729 (-)NCBINCBI36Build 36hg18NCBI36
Build 346155,808,616 - 155,869,150NCBI
Celera6156,450,814 - 156,511,369 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6153,278,816 - 153,339,381 (-)NCBIHuRef
CHM1_16155,978,832 - 156,039,365 (-)NCBICHM1_1
T2T-CHM13v2.06156,597,411 - 156,657,886 (-)NCBIT2T-CHM13v2.0
Nox3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39173,685,515 - 3,746,536 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl173,685,515 - 3,746,536 (-)EnsemblGRCm39 Ensembl
GRCm38173,635,240 - 3,696,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl173,635,240 - 3,696,261 (-)EnsemblGRCm38mm10GRCm38
MGSCv37173,635,240 - 3,696,261 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36173,591,722 - 3,652,743 (-)NCBIMGSCv36mm8
Celera174,177,588 - 4,238,207 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map172.05NCBI
Nox3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,643,277 - 46,708,109 (-)NCBIGRCr8
mRatBN7.2144,238,012 - 44,302,851 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,236,992 - 44,302,851 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx144,778,955 - 44,843,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,766,188 - 50,831,023 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,854,449 - 44,919,295 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,550,994 - 44,615,760 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,550,994 - 44,615,760 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,881,398 - 45,946,253 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4138,641,566 - 38,707,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1138,644,510 - 38,710,675 (-)NCBI
Celera139,871,599 - 39,935,812 (-)NCBICelera
Cytogenetic Map1q11NCBI
Nox3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554396,764,693 - 6,820,278 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554396,764,693 - 6,820,278 (+)NCBIChiLan1.0ChiLan1.0
NOX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25175,416,786 - 175,477,155 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16173,308,307 - 173,368,658 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06153,210,190 - 153,270,955 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16159,174,261 - 159,234,642 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6159,174,261 - 159,234,642 (-)Ensemblpanpan1.1panPan2
NOX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1145,129,112 - 45,186,510 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl145,128,958 - 45,186,510 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha145,966,130 - 46,023,558 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0145,312,920 - 45,370,432 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl145,309,796 - 45,370,432 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1145,181,678 - 45,239,667 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0145,051,482 - 45,109,473 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0145,607,812 - 45,665,301 (-)NCBIUU_Cfam_GSD_1.0
Nox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946140,316,169 - 140,371,377 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364897,569,620 - 7,623,369 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364897,568,162 - 7,623,370 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,445,956 - 11,501,979 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1111,443,681 - 11,501,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Nox3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247852,893,559 - 2,954,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247852,869,024 - 2,955,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 7 13 26
Below cutoff 13 4 34

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011332   ⟹   ENSCSAP00000009408
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1382,970,184 - 83,032,974 (-)Ensembl
RefSeq Acc Id: XM_038000735   ⟹   XP_037856663
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604055,340,628 - 55,441,413 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037856663 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009408.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000009408   ⟸   ENSCSAT00000011332
RefSeq Acc Id: XP_037856663   ⟸   XM_038000735
- UniProtKB: A0A0D9RLB9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011332.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.80 UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro Cyt_b245_heavy_chain UniProtKB/TrEMBL
  FAD-bd_8 UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/TrEMBL
  Fe3_Rdtase_TM_dom UniProtKB/TrEMBL
  Fe_red_NAD-bd_6 UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/TrEMBL
KEGG Report csab:103240766 UniProtKB/TrEMBL
NCBI Gene NOX3 ENTREZGENE
PANTHER NADPH OXIDASE UniProtKB/TrEMBL
  PTHR11972:SF12 UniProtKB/TrEMBL
Pfam FAD_binding_8 UniProtKB/TrEMBL
  Ferric_reduct UniProtKB/TrEMBL
  NAD_binding_6 UniProtKB/TrEMBL
PRINTS GP91PHOX UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/TrEMBL
Superfamily-SCOP SSF52343 UniProtKB/TrEMBL
  SSF63380 UniProtKB/TrEMBL
UniProt A0A0D9RLB9 ENTREZGENE, UniProtKB/TrEMBL