CD2 (CD2 molecule) - Rat Genome Database

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Gene: CD2 (CD2 molecule) Chlorocebus sabaeus
Analyze
Symbol: CD2
Name: CD2 molecule
RGD ID: 18649491
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase binding (ortholog); receptor tyrosine kinase binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); ASSOCIATED WITH genetic disease (ortholog); nephrotic syndrome (ortholog); prostate cancer (ortholog); FOUND IN cell surface (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-cell surface antigen CD2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12016,954,925 - 16,970,066 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2016,953,811 - 16,970,044 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603819,634,620 - 19,649,798 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12016,954,925 - 16,970,066 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2016,953,811 - 16,970,044 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603819,634,620 - 19,649,798 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381116,754,430 - 116,769,229 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1116,754,430 - 116,769,229 (+)EnsemblGRCh38hg38GRCh38
GRCh371117,297,052 - 117,311,851 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,098,609 - 117,113,374 (+)NCBINCBI36Build 36hg18NCBI36
Build 341117,009,143 - 117,023,892NCBI
Celera1115,525,598 - 115,540,363 (+)NCBICelera
Cytogenetic Map1p13.1NCBI
HuRef1115,156,224 - 115,170,989 (+)NCBIHuRef
CHM1_11117,411,979 - 117,426,744 (+)NCBICHM1_1
T2T-CHM13v2.01116,764,873 - 116,779,672 (+)NCBIT2T-CHM13v2.0
Cd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393101,183,224 - 101,195,255 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3101,183,215 - 101,195,255 (-)EnsemblGRCm39 Ensembl
GRCm383101,275,908 - 101,287,939 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3101,275,899 - 101,287,939 (-)EnsemblGRCm38mm10GRCm38
MGSCv373101,079,831 - 101,091,862 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363101,404,969 - 101,417,000 (-)NCBIMGSCv36mm8
Celera3103,490,645 - 103,502,693 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map344.17NCBI
Cd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82191,399,510 - 191,412,659 (-)NCBIGRCr8
mRatBN7.22188,710,895 - 188,724,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2188,710,900 - 188,724,026 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2196,344,644 - 196,357,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02194,196,679 - 194,209,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02189,021,373 - 189,034,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02203,666,706 - 203,680,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2203,666,637 - 203,680,083 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02223,111,198 - 223,124,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42196,332,547 - 196,346,221 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12196,295,300 - 196,660,648 (-)NCBI
Celera2181,149,611 - 181,162,644 (-)NCBICelera
Cytogenetic Map2q34NCBI
Cd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543519,861,527 - 19,873,581 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543519,861,658 - 19,876,383 (+)NCBIChiLan1.0ChiLan1.0
CD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21109,406,383 - 109,421,268 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11109,005,949 - 109,020,747 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,752,522 - 85,767,323 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11120,749,918 - 120,764,664 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1120,749,918 - 120,764,659 (-)Ensemblpanpan1.1panPan2
CD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11754,171,764 - 54,184,221 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1754,171,848 - 54,184,225 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1753,818,723 - 53,831,191 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01755,052,775 - 55,065,243 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1755,052,794 - 55,065,240 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11754,089,963 - 54,102,397 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01754,126,006 - 54,138,470 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01754,699,355 - 54,711,821 (+)NCBIUU_Cfam_GSD_1.0
Cd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505812,573,676 - 12,586,886 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366271,902,120 - 1,915,257 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366271,902,120 - 1,915,257 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4103,963,345 - 103,977,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14103,963,802 - 103,976,971 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24113,928,523 - 113,941,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Cd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477212,433,796 - 12,444,740 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477212,428,885 - 12,445,003 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20
Low 28 15
Below cutoff 8 20

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016834   ⟹   ENSCSAP00000016332
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2016,953,811 - 16,970,044 (-)Ensembl
RefSeq Acc Id: XM_007977425   ⟹   XP_007975616
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12016,954,925 - 16,970,066 (-)NCBI
Vero_WHO_p1.0NW_02366603819,634,620 - 19,649,798 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007977426   ⟹   XP_007975617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12016,954,925 - 16,970,066 (-)NCBI
Vero_WHO_p1.0NW_02366603819,634,620 - 19,649,798 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007975616 (Get FASTA)   NCBI Sequence Viewer  
  XP_007975617 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016332
  ENSCSAP00000016332.1
Reference Protein Sequences
RefSeq Acc Id: XP_007975617   ⟸   XM_007977426
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S643 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007975616   ⟸   XM_007977425
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000016332   ⟸   ENSCSAT00000016834


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001696 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016834.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD2 UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_C2-set UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene CD2 ENTREZGENE
PANTHER SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE UniProtKB/TrEMBL
  T-CELL SURFACE ANTIGEN CD2 UniProtKB/TrEMBL
Pfam C2-set UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PRINTS CD2ANTIGEN UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9S643 ENTREZGENE, UniProtKB/TrEMBL