HMGN5 (high mobility group nucleosome binding domain 5)

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Gene: HMGN5 (high mobility group nucleosome binding domain 5) Chlorocebus sabaeus

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Symbol:

HMGN5

Name:

high mobility group nucleosome binding domain 5

RGD ID:

18352004

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN chromatin organization (ortholog); glutathione metabolic process (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN chromatin (inferred); mitochondrion (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

high mobility group nucleosome-binding domain-containing protein 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	70,103,170 - 70,201,472 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	70,102,034 - 70,111,019 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666067	10,969,170 - 11,056,590 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

esophagus squamous cell carcinoma (ISO)

factor VIII deficiency (ISO)

high grade glioma (ISO)

Prostatic Neoplasms (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA,ISO)

glutathione metabolic process (ISO)

negative regulation of apoptotic process (IEA)

positive regulation of cell population proliferation (IEA)

positive regulation of gene expression (IEA)

regulation of transcription by RNA polymerase II (ISO)

Cellular Component

chromatin (IEA)

mitochondrion (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

chromatin binding (ISO)

nucleosomal DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HMGN5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	70,103,170 - 70,201,472 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	70,102,034 - 70,111,019 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666067	10,969,170 - 11,056,590 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

HMGN5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	81,113,699 - 81,201,913 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	81,113,699 - 81,201,913 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	80,369,198 - 80,457,412 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	80,255,856 - 80,263,772 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	80,175,344 - 80,183,261	NCBI
Celera	X	80,609,351 - 80,697,598 (-)	NCBI		Celera
Cytogenetic Map	X	q21.1	NCBI
HuRef	X	73,949,827 - 74,038,119 (-)	NCBI		HuRef
CHM1_1	X	80,262,599 - 80,350,840 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	79,547,434 - 79,635,633 (-)	NCBI		T2T-CHM13v2.0

Hmgn5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	108,048,143 - 108,056,986 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	108,048,140 - 108,057,010 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	109,004,537 - 109,013,380 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	109,004,534 - 109,013,404 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	106,199,876 - 106,208,719 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	105,207,254 - 105,216,078 (-)	NCBI		MGSCv36	mm8
Celera	X	95,826,022 - 95,834,509 (-)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	47.92	NCBI

Hmgn5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	78,161,439 - 78,170,613 (-)	NCBI		GRCr8
mRatBN7.2	X	74,085,871 - 74,094,488 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	74,085,875 - 74,094,441 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	117,222,298 - 117,223,587 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	75,599,179 - 75,607,745 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	79,072,736 - 79,081,073 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	76,638,296 - 76,646,633 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	80,134,557 - 80,142,902 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	80,134,557 - 80,142,902 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	80,311,866 - 80,320,211 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	75,355,864 - 75,364,432 (-)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Hmgn5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955529	1,118,706 - 1,125,596 (-)	NCBI	ChiLan1.0	ChiLan1.0

HMGN5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	80,580,338 - 80,668,236 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	80,583,949 - 80,671,847 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	70,180,585 - 70,268,545 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	80,285,151 - 80,373,078 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Hmgn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	56,287,079 - 56,341,448 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936547	2,607,491 - 2,614,037 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HMGN5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	64,541,310 - 64,617,345 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Hmgn5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624836	30,417 - 38,253 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007992164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037989493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037989495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000008708 ⟹ ENSCSAP00000006850

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	X	70,102,034 - 70,111,019 (-)	Ensembl

RefSeq Acc Id:

XM_007992164 ⟹ XP_007990355

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	X	70,103,170 - 70,201,472 (-)	NCBI
Vero_WHO_p1.0	NW_023666067	10,969,170 - 11,056,590 (+)	NCBI

Sequence:

show sequence

AATAGCACCGCGAGATCTGTTGAAACATTGATTTTTGACGATTCCTTCCCTGAGAAGAGAGAGA
GGAGAAGAAGAAAGAAAAAGGAGAACTGAATTGAATTAGATTAGCATGAAAGACCTTTTCACGC
GGAGACTAAAAGTGCTGCGCATAACTTCCTGCTCAGAAATGTATGCAAATAAGAAGACAGATCC
TGAAAGAGCAAGCTAGGAGAGTACAGGTCGTGCTGCAATTAGTTCATTGAAAACTCATTTGCTC
TTGGAGCAGTCAGGCAGTGACTGCCTTCGGCTTTTTTTCTGCTGACTAAGATCTCCTATAGAGA
GCTACAACAATGCCCAAAAGAAAGGCTGCAGGTCAAGGTGATATGAGGCAGGAGCCAAAGAGAA
GATCTGCCAGATTGTCTGCTATGCTTGTGCCCTTTACACCAGAGGTAATGCCCAAAAGAACATC
AAGTTCAAGGAAAATGAAGACAAAAAGTGATATGATGGAAGAAAACATAGATAAAAGTGCCCAA
GCAGTTGCTGAAACCAAGCAAGAAGCAGTTCTTGAAGAAGACTACAATGAAAATGCTAAAAATG
GAGAAGCCAAAATTACAGAGGCATCAGCTTCTGAAAAAGAAATTGTGGAAGTAAAAGAAGAAAA
TATTGAAGATGCCACAGAAAAGAGAGGAGAAAAGAAAGAAGCAGTGGCAGCAGAAGTAAAAAAT
GAAAAAGAAGATCAGAAAGAAGATGAAGAAGATAAAAACAAAGAAGAGAAAGGGGAAGCTGGAA
AAGAAGACAAGGATGAAAAAGGGAAAGAAGATGGAAAAGAGGATAAAAATGGAAATGAGAAAGG
AAAAGATGGAAAAGAGGAAGATGCAAAAGAGAAGGAAGATGGAAAAAAAGGTGAAGACGGAAAA
GGAAATGGAGAAGATGGAAAAGAGAAAGGAGAAGGTGAAAAAGAGGAAGAAGATAGAAAAGAAA
CAGGAGATGGAAAAACAAATGAAGATGGAAAAGAGAAAGGAGATGAAAAGGAGGAGAAAGATGT
AAAAGTCAAAGAAGATGAAAAAGAGAGAGAAGACGGAAAAGAAGATGAAGGTGGAAATGAGGAA
GAAGCTGGAATAGAGAAAGAAGATGAAGAAGAAGAAGAAGAAGGAAAAGAGAAAGACGAGATCA
AAGAAGAAGATGGAAAAATAGAGGAGCCGCAGAGTATTGTTTAAAACTGCCCTATATAGTTTCA
TAATTTGGTAACATGTACCTTCATGTTGTAAAGTTAATAGAGATAAATATTTTTATCAAAAATT
TTATAAACACAGTCTTTCTTTAGCATTGATTTAATTTCAGAACATCTTCATATTGATTTTTAGC
CATAAAGTTTCTAACATGAAACATTTATCTATAAATTTTGTGATTATAGTAGTGGAATATATAG
AAAAAATATGCTTTCAACTTTGCGAGTGAATTTCGTGTTGTGTAAGTTATGTGTCAAATCTTTG
AATTTTAATTTTACTCTTTTATATATGTGATAATTTCATAAAGTGAGGGATCCCAAAAAAAGAG
TTGCATCCAACGTTCTTGTTCTCTAGGATGCTTTTATAAAGAAGGTGAACTATTTTCATGTAAT
GCTAAGAGTTAAACTTATCTTTCCCAAATATAACTTTATTATTAGCTTGGGAAAAATGAAATTG
TATTTGCATTTTTAAAATAAATACATATGTTTATTTCAGAAGGGCAGTTTTGATTATATGTGAA
TGCACAAATTTTACTGGATTTATCTTAATAAAAAGACTCTGACGATGA

hide sequence

RefSeq Acc Id:

XM_037989493 ⟹ XP_037845421

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666067	10,969,248 - 11,056,590 (+)	NCBI

RefSeq Acc Id:

XM_037989495 ⟹ XP_037845423

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666067	11,031,204 - 11,056,590 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_007990355	(Get FASTA)	NCBI Sequence Viewer
	XP_037845421	(Get FASTA)	NCBI Sequence Viewer
	XP_037845423	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006850.1

RefSeq Acc Id:

XP_007990355 ⟸ XM_007992164

Ensembl Acc Id:

ENSCSAP00000006850 ⟸ ENSCSAT00000008708

RefSeq Acc Id:

XP_037845421 ⟸ XM_037989493

RefSeq Acc Id:

XP_037845423 ⟸ XM_037989495

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000010621	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000008708.1	UniProtKB/TrEMBL
InterPro	HMGN5	UniProtKB/TrEMBL
	HMGN_fam	UniProtKB/TrEMBL
KEGG Report	csab:103232264	UniProtKB/TrEMBL
NCBI Gene	HMGN5	ENTREZGENE
PANTHER	HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 5	UniProtKB/TrEMBL
	PTHR23145	UniProtKB/TrEMBL
Pfam	HMG14_17	UniProtKB/TrEMBL
PRINTS	NONHISHMG17	UniProtKB/TrEMBL
PROSITE	HMG14_17	UniProtKB/TrEMBL
SMART	HMG17	UniProtKB/TrEMBL
UniProt	A0A0D9RE11_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD