RNF31 (ring finger protein 31) - Rat Genome Database

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Gene: RNF31 (ring finger protein 31) Chlorocebus sabaeus
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Symbol: RNF31
Name: ring finger protein 31
RGD ID: 18668053
Description: ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN CD40 signaling pathway (ortholog); defense response to bacterium (ortholog); negative regulation of necroptotic process (ortholog); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN CD40 receptor complex (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF31
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,133,589 - 1,146,020 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,133,723 - 1,142,943 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,815,243 - 12,828,730 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,133,589 - 1,146,020 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,133,723 - 1,142,943 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,815,243 - 12,828,730 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RNF31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,146,875 - 24,160,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,146,683 - 24,160,660 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,616,084 - 24,629,864 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,686,499 - 23,699,710 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,686,545 - 23,699,706NCBI
Celera144,481,127 - 4,494,338 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,731,723 - 4,744,834 (+)NCBIHuRef
CHM1_11424,615,328 - 24,628,520 (+)NCBICHM1_1
T2T-CHM13v2.01418,345,184 - 18,358,964 (+)NCBIT2T-CHM13v2.0
Rnf31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,829,199 - 55,841,131 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,829,165 - 55,841,150 (+)EnsemblGRCm39 Ensembl
GRCm381455,591,713 - 55,603,674 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,591,708 - 55,603,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,210,627 - 56,222,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,545,861 - 54,557,742 (+)NCBIMGSCv36mm8
Celera1453,396,850 - 53,408,731 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Rnf31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,053,450 - 33,065,285 (+)NCBIGRCr8
mRatBN7.21529,083,047 - 29,095,328 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,083,631 - 29,101,915 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,929,372 - 30,941,042 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,076,578 - 32,088,240 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,318,920 - 30,330,582 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,270,037 - 34,282,385 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,270,648 - 34,282,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,160,162 - 38,172,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,727,541 - 33,739,204 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,742,598 - 33,754,894 (+)NCBI
Celera1528,659,586 - 28,671,248 (+)NCBICelera
Cytogenetic Map15p13NCBI
Rnf31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,240,008 - 36,252,166 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,240,008 - 36,252,166 (-)NCBIChiLan1.0ChiLan1.0
RNF31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,501,815 - 25,515,053 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,718,334 - 24,731,545 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,923,391 - 4,936,959 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,047,893 - 23,061,923 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,047,893 - 23,061,923 (+)Ensemblpanpan1.1panPan2
RNF31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,141,501 - 4,151,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,063,194 - 4,073,688 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,252,081 - 4,262,575 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,252,109 - 4,302,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,942,711 - 3,953,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,004,452 - 4,014,942 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,266,613 - 4,277,106 (+)NCBIUU_Cfam_GSD_1.0
Rnf31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,991,236 - 36,003,020 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722385,971 - 398,030 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722385,972 - 397,718 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Rnf31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,375,871 - 8,388,569 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,376,530 - 8,388,596 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 13 44
Low 7 16
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000014176   ⟹   ENSCSAP00000012155
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl241,133,723 - 1,142,943 (+)Ensembl
RefSeq Acc Id: XM_007986294   ⟹   XP_007984485
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,133,589 - 1,146,020 (+)NCBI
Vero_WHO_p1.0NW_02366603612,815,243 - 12,828,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037985453   ⟹   XP_037841381
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603612,815,713 - 12,828,730 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007984485 (Get FASTA)   NCBI Sequence Viewer  
  XP_037841381 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012155.1
RefSeq Acc Id: XP_007984485   ⟸   XM_007986294
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RU66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037841381   ⟸   XM_037985453
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RU66 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012155   ⟸   ENSCSAT00000014176


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016083 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014176.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1750 UniProtKB/TrEMBL
  1.20.58.2190 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  6.10.140.1100 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Zinc finger, RanBP2-type UniProtKB/TrEMBL
InterPro Bbox1_RNF31-like UniProtKB/TrEMBL
  BRcat_RBR_RNF31-like UniProtKB/TrEMBL
  IBR_dom UniProtKB/TrEMBL
  PUB-like_dom_sf UniProtKB/TrEMBL
  PUB_domain UniProtKB/TrEMBL
  RNF31-like UniProtKB/TrEMBL
  RNF31-UBA UniProtKB/TrEMBL
  RNF31_PUB UniProtKB/TrEMBL
  RNF31_RBR_mRING-HC-like UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  UBA_RNF31 UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene RNF31 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF31 UniProtKB/TrEMBL
  PTHR16004 UniProtKB/TrEMBL
Pfam HOIP-UBA UniProtKB/TrEMBL
  IBR UniProtKB/TrEMBL
  PUB UniProtKB/TrEMBL
  PUB_1 UniProtKB/TrEMBL
PROSITE TRIAD UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART IBR UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF143503 UniProtKB/TrEMBL
  SSF46934 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt A0A0D9RU66 ENTREZGENE, UniProtKB/TrEMBL