LOC103236155 (N-deacetylase and N-sulfotransferase 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: LOC103236155 (N-deacetylase and N-sulfotransferase 4) Chlorocebus sabaeus
Analyze
Symbol: LOC103236155 (Ensembl: NDST4)
Name: N-deacetylase and N-sulfotransferase 4
RGD ID: 18611667
Description: ENCODES a protein that exhibits N-acetylglucosamine deacetylase activity (ortholog); sulfotransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (inferred); heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process (inferred); heparin biosynthetic process (inferred); ASSOCIATED WITH genetic disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN Golgi apparatus (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; NDST4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1762,619,344 - 62,911,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl762,622,455 - 62,874,293 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603741,400,330 - 41,691,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103236155
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1762,619,344 - 62,911,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl762,622,455 - 62,874,293 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603741,400,330 - 41,691,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NDST4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384114,827,763 - 115,113,620 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4114,827,763 - 115,113,876 (-)EnsemblGRCh38hg38GRCh38
GRCh374115,748,919 - 116,034,776 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364115,968,368 - 116,254,481 (-)NCBINCBI36Build 36hg18NCBI36
Build 344116,106,534 - 116,392,636NCBI
Celera4113,041,908 - 113,327,826 (-)NCBICelera
Cytogenetic Map4q26NCBI
HuRef4111,482,596 - 111,769,024 (-)NCBIHuRef
CHM1_14115,724,868 - 116,011,407 (-)NCBICHM1_1
T2T-CHM13v2.04118,130,762 - 118,416,573 (-)NCBIT2T-CHM13v2.0
Ndst4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393125,197,678 - 125,522,550 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3125,197,725 - 125,522,548 (+)EnsemblGRCm39 Ensembl
GRCm383125,404,029 - 125,728,351 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3125,404,076 - 125,728,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv373125,107,009 - 125,427,904 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363125,429,702 - 125,716,801 (+)NCBIMGSCv36mm8
Celera3131,829,352 - 132,166,533 (+)NCBICelera
Cytogenetic Map3G1NCBI
cM Map354.68NCBI
Ndst4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82216,461,542 - 216,794,035 (+)NCBIGRCr8
mRatBN7.22213,787,010 - 214,119,514 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2213,787,006 - 214,115,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2221,478,116 - 221,786,835 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02219,378,038 - 219,686,766 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02214,232,235 - 214,540,962 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02229,170,781 - 229,496,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2229,196,616 - 229,496,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02248,525,754 - 248,852,279 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42222,503,566 - 222,815,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12222,464,480 - 222,801,974 (+)NCBI
Celera2206,169,234 - 206,462,526 (+)NCBICelera
Cytogenetic Map2q42NCBI
Ndst4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542824,346,191 - 24,637,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542824,376,587 - 24,636,555 (+)NCBIChiLan1.0ChiLan1.0
LOC100986527
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23112,934,751 - 113,225,893 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14113,229,950 - 113,517,255 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04107,345,741 - 107,636,362 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14117,911,985 - 118,198,128 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4117,911,985 - 118,198,128 (-)Ensemblpanpan1.1panPan2
NDST4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13234,347,865 - 34,606,763 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3234,351,162 - 34,631,039 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha327,419,676 - 7,678,620 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03234,574,096 - 34,827,803 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3234,577,757 - 34,860,678 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13234,573,089 - 34,839,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03234,320,965 - 34,574,566 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0325,288,077 - 5,540,829 (+)NCBIUU_Cfam_GSD_1.0
Ndst4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053016,216,365 - 6,478,642 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365635,430,444 - 5,664,126 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365635,434,668 - 5,664,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDST4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8107,910,973 - 108,123,325 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18107,882,088 - 108,129,785 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28116,087,271 - 116,176,521 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ndst4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248671,466,845 - 1,750,240 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248671,463,933 - 1,750,490 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 1
Low 3 10 41
Below cutoff 19 7 18

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007999644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000001804   ⟹   ENSCSAP00000000142
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl762,622,455 - 62,874,293 (-)Ensembl
RefSeq Acc Id: XM_007999644   ⟹   XP_007997835
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1762,619,344 - 62,911,843 (-)NCBI
Vero_WHO_p1.0NW_02366603741,400,330 - 41,691,435 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007997835 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000142
  ENSCSAP00000000142.1
Reference Protein Sequences
RefSeq Acc Id: XP_007997835   ⟸   XM_007999644
- UniProtKB: A0A0D9QUV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000142   ⟸   ENSCSAT00000001804


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003784 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001804.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Heparan_SO4_deacetylase UniProtKB/TrEMBL
  NST/OST UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
NCBI Gene NDST4 ENTREZGENE
PANTHER BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 4 UniProtKB/TrEMBL
  PTHR10605 UniProtKB/TrEMBL
Pfam HSNSD UniProtKB/TrEMBL
  Sulfotransfer_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9QUV3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103236155  N-deacetylase and N-sulfotransferase 4  NDST4  N-deacetylase and N-sulfotransferase 4  Symbol and/or name change 5135510 APPROVED