CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: uranium atom
Accession: CHEBI:27214
browse the term
Definition: An actinoid atom that has formula U.
Synonyms: related_synonym: 92U; Formula=U; InChI=1S/U; InChIKey=JFALSRSLKYAFGM-UHFFFAOYSA-N; SMILES=[U]; U; Uran; uranio; uranium
xref: CAS:7440-61-1
xref_mesh: MESH:D014501
xref: WebElements:U
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1110059G10Rik
RIKEN cDNA 1110059G10 gene
increases expression
ISO
Uranium results in increased expression of KIAA1143 mRNA
CTD
PMID:15672453
NCBI chr 9:122,774,154...122,780,065
Ensembl chr 9:122,774,154...122,780,065
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2210016L21Rik
RIKEN cDNA 2210016L21 gene
affects expression
ISO
Uranium affects the expression of C12ORF43 mRNA
CTD
PMID:15672453
NCBI chr 5:115,080,213...115,086,610
Ensembl chr 5:115,080,217...115,087,842
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4933434E20Rik
RIKEN cDNA 4933434E20 gene
affects expression
ISO
Uranium affects the expression of C1ORF43 mRNA
CTD
PMID:15672453
NCBI chr 3:89,958,941...89,969,754
Ensembl chr 3:89,958,943...89,970,648 Ensembl chr 3:89,958,943...89,970,648
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Aadat
aminoadipate aminotransferase
affects expression
ISO
Uranium affects the expression of AADAT mRNA
CTD
PMID:15672453
NCBI chr 8:60,958,877...60,998,711
Ensembl chr 8:60,958,966...60,998,711
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Aanat
arylalkylamine N-acetyltransferase
affects expression
ISO
Uranium affects the expression of AANAT mRNA
CTD
PMID:15672453
NCBI chr11:116,482,547...116,489,022
Ensembl chr11:116,477,258...116,488,506
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Aasdhppt
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
affects expression
ISO
Uranium affects the expression of AASDHPPT mRNA
CTD
PMID:15672453
NCBI chr 9:4,294,793...4,309,656
Ensembl chr 9:4,294,793...4,309,471
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Abcc2
ATP-binding cassette, sub-family member 2
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in increased expression of ABCC2 mRNA; Uranium analog promotes the reaction [Acetaminophen results in increased expression of ABCC2 mRNA]
CTD
PMID:17126469
NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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Abcc8
ATP-binding cassette, sub-family C member 8
affects expression
ISO
Uranium affects the expression of ABCC8 mRNA
CTD
PMID:15672453
NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457
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Abcf2
ATP-binding cassette, sub-family F member 2
affects expression
ISO
Uranium affects the expression of ABCF2 mRNA
CTD
PMID:15672453
NCBI chr 5:24,770,339...24,782,465
Ensembl chr 5:24,770,343...24,782,465
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Acat2
acetyl-Coenzyme A acetyltransferase 2
affects expression
ISO
Uranium affects the expression of ACAT2 mRNA
CTD
PMID:15672453
NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
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Acp5
acid phosphatase 5, tartrate resistant
increases expression multiple interactions increases secretion
ISO
Uranium results in increased expression of ACP5 protein GHRL protein inhibits the reaction [Uranium results in increased secretion of ACP5 protein]
CTD
PMID:16436523 PMID:29477364
NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
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Actb
actin, beta
affects expression
ISO
Uranium affects the expression of ACTB mRNA; Uranium affects the expression of ACTB protein
CTD
PMID:15672453
NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
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Actr2
actin related protein 2
affects expression
ISO
Uranium affects the expression of ACTR2 mRNA
CTD
PMID:15672453
NCBI chr11:20,012,304...20,062,951
Ensembl chr11:20,012,304...20,062,913
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Adar
adenosine deaminase, RNA-specific
affects expression
ISO
Uranium affects the expression of ADAR mRNA
CTD
PMID:15672453
NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753
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Adnp
activity-dependent neuroprotective protein
affects expression
ISO
Uranium affects the expression of ADNP mRNA
CTD
PMID:15672453
NCBI chr 2:168,022,885...168,049,032
Ensembl chr 2:168,022,906...168,049,032
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Akap1
A kinase anchor protein 1
affects expression
ISO
Uranium affects the expression of AKAP1 mRNA
CTD
PMID:15672453
NCBI chr11:88,721,618...88,755,426
Ensembl chr11:88,721,618...88,755,412
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Akirin1
akirin 1
increases expression
ISO
Uranium results in increased expression of AKIRIN1 mRNA
CTD
PMID:15672453
NCBI chr 4:123,628,988...123,644,092
Ensembl chr 4:123,628,352...123,644,138
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Akr1c18
aldo-keto reductase family 1, member C18
affects expression
ISO
Uranium affects the expression of AKR1C3 mRNA
CTD
PMID:15672453
NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
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Alpl
alkaline phosphatase, liver/bone/kidney
multiple interactions decreases secretion
ISO
GHRL protein inhibits the reaction [Uranium results in decreased secretion of ALPL protein]
CTD
PMID:29477364
NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
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Apbb1
amyloid beta precursor protein binding family B member 1
affects expression
ISO
Uranium affects the expression of APBB1 mRNA
CTD
PMID:15672453
NCBI chr 7:105,207,691...105,231,151
Ensembl chr 7:105,207,690...105,230,860
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Apc
APC, WNT signaling pathway regulator
affects expression
ISO
Uranium affects the expression of APC mRNA
CTD
PMID:15672453
NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
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Aplnr
apelin receptor
decreases expression
ISO
Uranium results in decreased expression of APLNR mRNA
CTD
PMID:37270086
NCBI chr 2:84,966,704...84,970,267
Ensembl chr 2:84,966,569...84,970,267
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App
amyloid beta precursor protein
affects expression
ISO
Uranium affects the expression of APP mRNA
CTD
PMID:15672453
NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
affects expression
ISO
Uranium affects the expression of APPL1 mRNA
CTD
PMID:15672453
NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189
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Ar
androgen receptor
decreases expression
ISO
Uranium analog results in decreased expression of AR mRNA
CTD
PMID:27544493
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Armc9
armadillo repeat containing 9
increases expression
ISO
Uranium results in increased expression of ARMC9 mRNA
CTD
PMID:15672453
NCBI chr 1:86,082,436...86,207,491
Ensembl chr 1:86,082,502...86,206,006
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Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
affects expression
ISO
Uranium affects the expression of ASAP2 mRNA
CTD
PMID:15672453
NCBI chr12:21,161,369...21,320,172
Ensembl chr12:21,040,460...21,320,172
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Ascl1
achaete-scute family bHLH transcription factor 1
increases expression
ISO
Uranium results in increased expression of ASCL1 mRNA
CTD
PMID:27639536
NCBI chr10:87,326,681...87,329,522
Ensembl chr10:87,326,681...87,329,522
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Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
affects expression
ISO
Uranium affects the expression of ATP6V1A mRNA
CTD
PMID:15672453
NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
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Atp9b
ATPase, class II, type 9B
affects expression
ISO
Uranium affects the expression of ATP9B mRNA
CTD
PMID:15672453
NCBI chr18:80,777,356...80,977,291
Ensembl chr18:80,777,356...80,977,275
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Atxn10
ataxin 10
affects expression
ISO
Uranium affects the expression of ATXN10 mRNA
CTD
PMID:15672453
NCBI chr15:85,220,456...85,348,038
Ensembl chr15:85,220,446...85,347,413
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B2m
beta-2 microglobulin
affects expression
ISO
Uranium affects the expression of B2M mRNA
CTD
PMID:15672453
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
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Baalc
brain and acute leukemia, cytoplasmic
affects expression
ISO
Uranium affects the expression of BAALC mRNA
CTD
PMID:15672453
NCBI chr15:38,739,763...38,814,659
Ensembl chr15:38,740,784...38,816,307
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Bace1
beta-site APP cleaving enzyme 1
affects expression
ISO
Uranium affects the expression of BACE mRNA
CTD
PMID:15672453
NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697
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Bglap
bone gamma carboxyglutamate protein
increases expression decreases secretion multiple interactions
ISO EXP
Uranium results in increased expression of BGLAP protein Uranium results in decreased secretion of BGLAP protein GHRL protein inhibits the reaction [Uranium results in decreased secretion of BGLAP protein] Uranium results in increased expression of BGLAP mRNA
CTD
PMID:16436523 PMID:29477364 PMID:31120128
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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Bgn
biglycan
affects expression
ISO
Uranium affects the expression of BGN mRNA
CTD
PMID:15672453
NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539
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Btf3
basic transcription factor 3
affects expression
ISO
Uranium affects the expression of BTF3 mRNA
CTD
PMID:15672453
NCBI chr13:98,446,405...98,453,514
Ensembl chr13:98,446,404...98,453,514
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Calb1
calbindin 1
decreases expression
ISO
Uranium results in decreased expression of CALB1 mRNA
CTD
PMID:17118558
NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
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Calm2
calmodulin 2
affects expression
ISO
Uranium affects the expression of CALM2 mRNA
CTD
PMID:15672453
NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363
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Camk2d
calcium/calmodulin-dependent protein kinase II, delta
affects expression
ISO
Uranium affects the expression of CAMK2D mRNA
CTD
PMID:15672453
NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975
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Canx
calnexin
affects expression
ISO
Uranium affects the expression of CANX mRNA
CTD
PMID:15672453
NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
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Casp3
caspase 3
multiple interactions increases activity increases expression
ISO
EIF2AK3 protein promotes the reaction [Uranium results in increased expression of CASP3 protein]; GHRL protein inhibits the reaction [Uranium results in increased activity of CASP3 protein]; THBS1 protein inhibits the reaction [Uranium results in increased expression of CASP3 protein]
CTD
PMID:29477364 PMID:37270086
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Cbfa2t2
CBFA2/RUNX1 translocation partner 2
affects expression
ISO
Uranium affects the expression of CBFA2T2 mRNA
CTD
PMID:15672453
NCBI chr 2:154,278,018...154,381,276
Ensembl chr 2:154,278,401...154,381,276
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Ccl2
C-C motif chemokine ligand 2
decreases expression
ISO
Uranium results in decreased expression of CCL2 mRNA; Uranium results in decreased expression of CCL2 protein
CTD
PMID:16854789 PMID:17566059
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Chchd5
coiled-coil-helix-coiled-coil-helix domain containing 5
increases expression
ISO
Uranium results in increased expression of CHCHD5 mRNA
CTD
PMID:15672453
NCBI chr 2:128,971,620...128,976,032
Ensembl chr 2:128,971,620...128,976,054
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Chrdl1
chordin-like 1
increases expression
ISO
Uranium results in increased expression of CHRDL1 mRNA
CTD
PMID:15672453
NCBI chr X:142,068,670...142,177,282
Ensembl chr X:142,068,670...142,177,258
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Churc1
churchill domain containing 1
increases expression
ISO
Uranium results in increased expression of CHURC1 mRNA
CTD
PMID:15672453
NCBI chr12:76,812,312...76,829,954
Ensembl chr12:76,812,312...76,829,954
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Clint1
clathrin interactor 1
affects expression
ISO
Uranium affects the expression of CLINT1 mRNA
CTD
PMID:15672453
NCBI chr11:45,742,797...45,801,452
Ensembl chr11:45,742,791...45,801,452
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Clstn3
calsyntenin 3
affects expression
ISO
Uranium affects the expression of CLSTN3 mRNA
CTD
PMID:15672453
NCBI chr 6:124,407,715...124,441,743
Ensembl chr 6:124,407,540...124,441,753
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Cog7
component of oligomeric golgi complex 7
affects expression
ISO
Uranium affects the expression of COG7 mRNA
CTD
PMID:15672453
NCBI chr 7:121,522,059...121,580,940
Ensembl chr 7:121,478,586...121,580,934
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Col1a1
collagen, type I, alpha 1
increases expression
EXP
Uranium results in increased expression of COL1A1 mRNA
CTD
PMID:31120128
NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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Cops3
COP9 signalosome subunit 3
affects expression
ISO
Uranium affects the expression of COPS3 mRNA
CTD
PMID:15672453
NCBI chr11:59,708,621...59,739,080
Ensembl chr11:59,708,621...59,730,664
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Cp
ceruloplasmin
increases expression
ISO
Uranium results in increased expression of CP mRNA
CTD
PMID:18375546
NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
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Crls1
cardiolipin synthase 1
affects expression
ISO
Uranium affects the expression of CRLS1 mRNA
CTD
PMID:15672453
NCBI chr 2:132,688,557...132,708,706
Ensembl chr 2:132,688,586...132,708,705
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Crybb2
crystallin, beta B2
affects expression
ISO
Uranium affects the expression of CRYBB2 mRNA
CTD
PMID:15672453
NCBI chr 5:113,206,124...113,217,983
Ensembl chr 5:113,206,124...113,217,983
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Csde1
cold shock domain containing E1, RNA binding
affects expression
ISO
Uranium affects the expression of CSDE1 mRNA
CTD
PMID:15672453
NCBI chr 3:102,927,347...102,965,502
Ensembl chr 3:102,927,742...102,965,502
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Cstpp1
centriolar satellite-associated tubulin polyglutamylase complex regulator 1
affects expression
ISO
Uranium affects the expression of CSTPP1 mRNA
CTD
PMID:15672453
NCBI chr 2:91,103,585...91,275,059
Ensembl chr 2:91,105,413...91,275,049
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Ctcf
CCCTC-binding factor
affects expression
ISO
Uranium affects the expression of CTCF mRNA
CTD
PMID:15672453
NCBI chr 8:106,351,135...106,409,554
Ensembl chr 8:106,363,200...106,409,554
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Ctnnb1
catenin beta 1
decreases expression
ISO
Uranium analog results in decreased expression of CTNNB1 mRNA
CTD
PMID:27544493
NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
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Ctrl
chymotrypsin-like
affects expression
ISO
Uranium affects the expression of CTRL mRNA
CTD
PMID:15672453
NCBI chr 8:106,658,626...106,660,494
Ensembl chr 8:106,658,635...106,660,494
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Cul2
cullin 2
affects expression
ISO
Uranium affects the expression of CUL2 mRNA
CTD
PMID:15672453
NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression
ISO
Uranium analog results in decreased expression of CYP11A1 mRNA
CTD
PMID:27544493
NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
ISO
Uranium analog results in decreased expression of CYP17A1 mRNA
CTD
PMID:27544493
NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
decreases expression
ISO
Uranium results in decreased expression of CYP24A1 mRNA
CTD
PMID:17118558
NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases activity decreases expression increases activity
ISO
Uranium results in decreased activity of CYP27A1 protein Uranium results in decreased expression of CYP27A1 mRNA Uranium results in increased activity of CYP27A1 protein
CTD
PMID:16231126 PMID:16502312 PMID:17118558
NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression
ISO
Uranium results in increased expression of CYP27B1 mRNA
CTD
PMID:16502312
NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
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Cyp2c52-ps
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2C11 mRNA
CTD
PMID:17126469
NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA; Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]
CTD
PMID:17126469
NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
increases expression
ISO
Uranium results in increased expression of CYP2R1 mRNA
CTD
PMID:16502312
NCBI chr 7:114,149,358...114,162,283
Ensembl chr 7:114,148,917...114,162,207
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Ddit3
DNA-damage inducible transcript 3
increases expression multiple interactions
ISO
Uranium results in increased expression of DDIT3 mRNA EIF2AK3 protein promotes the reaction [Uranium results in increased expression of DDIT3 protein]; THBS1 protein inhibits the reaction [Uranium results in increased expression of DDIT3 protein]
CTD
PMID:14971665 PMID:37270086
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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Dgka
diacylglycerol kinase, alpha
affects expression
ISO
Uranium affects the expression of DGKA mRNA
CTD
PMID:15672453
NCBI chr10:128,556,000...128,581,002
Ensembl chr10:128,556,003...128,580,724
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Dixdc1
DIX domain containing 1
affects expression
ISO
Uranium affects the expression of DIXDC1 mRNA
CTD
PMID:15672453
NCBI chr 9:50,574,052...50,650,900
Ensembl chr 9:50,574,052...50,650,817
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Dmp1
dentin matrix protein 1
decreases expression
EXP
Uranium results in decreased expression of DMP1 mRNA
CTD
PMID:31120128
NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968
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Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
affects expression
ISO
Uranium affects the expression of DNAJA2 mRNA
CTD
PMID:15672453
NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973
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Dnajc9
DnaJ heat shock protein family (Hsp40) member C9
affects expression
ISO
Uranium affects the expression of DNAJC9 mRNA
CTD
PMID:15672453
NCBI chr14:20,434,706...20,438,978
Ensembl chr14:20,434,706...20,438,978
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Dnmt1
DNA methyltransferase 1
increases expression
ISO
Uranium results in increased expression of DNMT1 mRNA
CTD
PMID:29024790
NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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Dnmt3a
DNA methyltransferase 3A
increases expression
ISO
Uranium results in increased expression of DNMT3A mRNA
CTD
PMID:29024790
NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
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Dnmt3b
DNA methyltransferase 3B
increases expression
ISO
Uranium results in increased expression of DNMT3B mRNA
CTD
PMID:29024790
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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Dnmt3l
DNA methyltransferase 3-like
affects expression
ISO
Uranium affects the expression of DNMT3L mRNA
CTD
PMID:29024790
NCBI chr10:77,878,121...77,899,456
Ensembl chr10:77,877,781...77,899,456
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Dpysl5
dihydropyrimidinase-like 5
increases expression
ISO
Uranium results in increased expression of DPYSL5 mRNA
CTD
PMID:15672453
NCBI chr 5:30,868,908...30,956,713
Ensembl chr 5:30,868,908...30,956,719
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Dstyk
dual serine/threonine and tyrosine protein kinase
affects expression
ISO
Uranium affects the expression of DSTYK mRNA
CTD
PMID:15672453
NCBI chr 1:132,345,127...132,394,697
Ensembl chr 1:132,345,293...132,394,696
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Dtna
dystrobrevin alpha
increases expression
ISO
Uranium results in increased expression of DTNA mRNA
CTD
PMID:15672453
NCBI chr18:23,443,063...23,792,776
Ensembl chr18:23,548,192...23,792,772
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Dtymk
deoxythymidylate kinase
affects expression
ISO
Uranium affects the expression of DTYMK mRNA
CTD
PMID:15672453
NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
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Dzank1
double zinc ribbon and ankyrin repeat domains 1
increases expression
ISO
Uranium results in increased expression of DZANK1 mRNA
CTD
PMID:15672453
NCBI chr 2:144,312,475...144,369,427
Ensembl chr 2:144,312,477...144,369,334
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Eef1a1
eukaryotic translation elongation factor 1 alpha 1
affects expression
ISO
Uranium affects the expression of EEF1A1 mRNA
CTD
PMID:15672453
NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433
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Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
ISO
Uranium affects the expression of EEF1G mRNA
CTD
PMID:15672453
NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843
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Eif1
eukaryotic translation initiation factor 1
affects expression
ISO
Uranium affects the expression of EIF1 mRNA
CTD
PMID:15672453
NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases expression multiple interactions
ISO
Uranium results in increased expression of EIF2AK3 mRNA; Uranium results in increased expression of EIF2AK3 protein EIF2AK3 protein promotes the reaction [Uranium results in increased expression of CASP3 protein]; EIF2AK3 protein promotes the reaction [Uranium results in increased expression of DDIT3 protein]; THBS1 protein inhibits the reaction [Uranium results in increased expression of EIF2AK3 mRNA]; THBS1 protein inhibits the reaction [Uranium results in increased expression of EIF2AK3 protein]
CTD
PMID:37270086
NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
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Epor
erythropoietin receptor
decreases expression
ISO
Uranium results in decreased expression of EPOR mRNA
CTD
PMID:18375546
NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
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Eps15
epidermal growth factor receptor pathway substrate 15
affects expression
ISO
Uranium affects the expression of EPS15 mRNA
CTD
PMID:15672453
NCBI chr 4:109,137,372...109,245,014
Ensembl chr 4:109,137,465...109,245,014
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Erbb3
erb-b2 receptor tyrosine kinase 3
affects expression
ISO
Uranium affects the expression of ERBB3 mRNA
CTD
PMID:15672453
NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
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Evi5
ecotropic viral integration site 5
affects expression
ISO
Uranium affects the expression of EVI5 mRNA
CTD
PMID:15672453
NCBI chr 5:107,892,661...108,022,973
Ensembl chr 5:107,892,661...108,022,973
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Evl
Ena-vasodilator stimulated phosphoprotein
affects expression
ISO
Uranium affects the expression of EVL mRNA
CTD
PMID:15672453
NCBI chr12:108,520,942...108,654,775
Ensembl chr12:108,520,979...108,654,775
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Fam3c
FAM3 metabolism regulating signaling molecule C
affects expression
ISO
Uranium affects the expression of FAM3C mRNA
CTD
PMID:15672453
NCBI chr 6:22,306,519...22,356,080
Ensembl chr 6:22,306,519...22,356,242
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Fasl
Fas ligand
increases expression
ISO
Uranium results in increased expression of FASLG mRNA
CTD
PMID:16854789
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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Fmo3
flavin containing monooxygenase 3
increases expression
ISO
Uranium results in increased expression of FMO3 mRNA
CTD
PMID:37270086
NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097
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Fos
FBJ osteosarcoma oncogene
increases expression
ISO
Uranium results in increased expression of FOS mRNA
CTD
PMID:14971665
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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Fshb
follicle stimulating hormone beta
increases expression
ISO
Uranium analog results in increased expression of FSHB protein
CTD
PMID:27544493
NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
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Fut8
fucosyltransferase 8
affects expression
ISO
Uranium affects the expression of FUT8 mRNA
CTD
PMID:15672453
NCBI chr12:77,284,878...77,522,770
Ensembl chr12:77,284,899...77,523,112
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G3bp1
G3BP stress granule assembly factor 1
affects expression
ISO
Uranium affects the expression of G3BP1 mRNA
CTD
PMID:15672453
NCBI chr11:55,360,521...55,391,722
Ensembl chr11:55,360,511...55,395,664
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Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
increases expression
ISO
Uranium results in increased expression of GADD45A mRNA
CTD
PMID:14971665
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
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Gata6
GATA binding protein 6
decreases expression
ISO
Uranium analog results in decreased expression of GATA6 mRNA
CTD
PMID:27544493
NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
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Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
decreases expression
ISO
Uranium results in decreased expression of GFRA1 mRNA
CTD
PMID:37270086
NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341
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Ghrl
ghrelin
decreases response to substance multiple interactions decreases expression
EXP ISO
GHRL protein results in decreased susceptibility to Uranium GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]; GHRL protein inhibits the reaction [Uranium results in decreased expression of GHSR protein]; GHRL protein inhibits the reaction [Uranium results in decreased secretion of ALPL protein]; GHRL protein inhibits the reaction [Uranium results in decreased secretion of BGLAP protein]; GHRL protein inhibits the reaction [Uranium results in increased activity of CASP3 protein]; GHRL protein inhibits the reaction [Uranium results in increased expression of and results in increased secretion of TNFSF11 protein]; GHRL protein inhibits the reaction [Uranium results in increased secretion of ACP5 protein] Anisomycin inhibits the reaction [GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]]; Anisomycin inhibits the reaction [GHRL protein inhibits the reaction [Uranium results in increased expression of and results in increased secretion of TNFSF11 protein]]; GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]; GHRL protein inhibits the reaction [Uranium results in increased expression of and results in increased secretion of TNFSF11 protein] Uranium results in decreased expression of GHRL protein
CTD
PMID:29477364
NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
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Ghsr
growth hormone secretagogue receptor
multiple interactions decreases expression
ISO
GHRL protein inhibits the reaction [Uranium results in decreased expression of GHSR protein]
CTD
PMID:29477364
NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159
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Glo1
glyoxalase 1
affects expression
ISO
Uranium affects the expression of GLO1 mRNA
CTD
PMID:15672453
NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
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Glul
glutamate-ammonia ligase
affects expression
ISO
Uranium affects the expression of GLUL mRNA
CTD
PMID:15672453
NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
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Gpx1
glutathione peroxidase 1
affects expression decreases expression
ISO
Uranium affects the expression of GPX1 mRNA Uranium analog results in decreased expression of GPX1 mRNA
CTD
PMID:15672453 PMID:27544493
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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Grb2
growth factor receptor bound protein 2
affects expression
ISO
Uranium affects the expression of GRB2 mRNA
CTD
PMID:15672453
NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423
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Gspt1
G1 to S phase transition 1
increases expression
ISO
Uranium results in increased expression of GSPT1 mRNA
CTD
PMID:15672453
NCBI chr16:11,034,104...11,072,189
Ensembl chr16:11,037,156...11,072,189
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Gsta2
glutathione S-transferase, alpha 2 (Yc2)
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in decreased expression of GSTA2 mRNA; Uranium analog promotes the reaction [Acetaminophen results in increased expression of GSTA2 mRNA]
CTD
PMID:17126469
NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
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Gstp1
glutathione S-transferase, pi 1
decreases expression increases expression
ISO
Uranium analog results in decreased expression of GSTP1 mRNA Uranium results in increased expression of GSTP1 mRNA
CTD
PMID:27544493 PMID:37270086
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
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H2-T23
histocompatibility 2, T region locus 23
affects expression
ISO
Uranium affects the expression of HLA-E mRNA
CTD
PMID:15672453
NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747
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H2bc1
H2B clustered histone 1
decreases expression
ISO
Uranium analog results in decreased expression of H2BC1 mRNA
CTD
PMID:27544493
NCBI chr13:24,117,708...24,118,139
Ensembl chr13:24,117,756...24,118,139
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Hadh
hydroxyacyl-Coenzyme A dehydrogenase
affects expression
ISO
Uranium affects the expression of HADH mRNA
CTD
PMID:15672453
NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750
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Hbp1
high mobility group box transcription factor 1
affects expression
ISO
Uranium affects the expression of HBP1 mRNA
CTD
PMID:15672453
NCBI chr12:31,976,449...32,000,529
Ensembl chr12:31,976,253...32,000,534
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Hmgb1
high mobility group box 1
affects expression
ISO
Uranium affects the expression of HMGB1 mRNA; Uranium affects the expression of HMGB1 protein
CTD
PMID:15672453
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
G
Hmox2
heme oxygenase 2
increases expression
ISO
Uranium results in increased expression of HMOX2 mRNA
CTD
PMID:18375546
NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
G
Hnf4a
hepatic nuclear factor 4, alpha
increases expression
ISO
Uranium results in increased expression of HNF4A mRNA
CTD
PMID:17118558
NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
G
Hnrnpc
heterogeneous nuclear ribonucleoprotein C
affects expression
ISO
Uranium affects the expression of HNRNPC mRNA
CTD
PMID:15672453
NCBI chr14:52,310,834...52,341,462
Ensembl chr14:52,310,834...52,341,485
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression
ISO
Uranium analog results in decreased expression of HSD3B1 mRNA
CTD
PMID:27544493
NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
G
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
affects expression
ISO
Uranium affects the expression of HSP90AB1 mRNA; Uranium affects the expression of HSP90AB1 protein
CTD
PMID:15672453
NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
G
Hspa5
heat shock protein 5
increases expression
ISO
Uranium results in increased expression of HSPA5 mRNA
CTD
PMID:14971665
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
G
Iars2
isoleucine-tRNA synthetase 2, mitochondrial
affects expression
ISO
Uranium affects the expression of IARS2 mRNA
CTD
PMID:15672453
NCBI chr 1:185,018,839...185,061,615
Ensembl chr 1:185,016,923...185,061,593
G
Id2
inhibitor of DNA binding 2
affects expression
ISO
Uranium affects the expression of ID2 mRNA
CTD
PMID:15672453
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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Ifng
interferon gamma
increases expression decreases secretion
ISO EXP
Uranium results in increased expression of IFNG mRNA Uranium results in decreased secretion of IFNG protein
CTD
PMID:16854789 PMID:23659960
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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Ifrd2
interferon-related developmental regulator 2
affects expression
ISO
Uranium affects the expression of IFRD2 mRNA
CTD
PMID:15672453
NCBI chr 9:107,464,917...107,470,237
Ensembl chr 9:107,464,841...107,470,584
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Ik
IK cytokine
affects expression
ISO
Uranium affects the expression of IK mRNA
CTD
PMID:15672453
NCBI chr18:36,877,709...36,890,692
Ensembl chr18:36,877,731...36,890,688
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Il10
interleukin 10
increases expression increases secretion
ISO EXP
Uranium results in increased expression of IL10 mRNA Uranium results in increased secretion of IL10 protein
CTD
PMID:17566059 PMID:23659960
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il18
interleukin 18
decreases secretion
EXP
Uranium results in decreased secretion of IL18 protein
CTD
PMID:23659960
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Il1b
interleukin 1 beta
increases expression decreases secretion
ISO EXP
Uranium results in increased expression of IL1B mRNA Uranium results in decreased secretion of IL1B protein
CTD
PMID:17566059 PMID:23659960
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il4
interleukin 4
increases secretion
EXP
Uranium results in increased secretion of IL4 protein
CTD
PMID:23659960
NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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Insig1
insulin induced gene 1
affects expression
ISO
Uranium affects the expression of INSIG1 mRNA
CTD
PMID:15672453
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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Iqgap2
IQ motif containing GTPase activating protein 2
affects expression
ISO
Uranium affects the expression of IQGAP2 mRNA
CTD
PMID:15672453
NCBI chr13:95,763,685...96,028,788
Ensembl chr13:95,763,682...96,028,991
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Kazn
kazrin, periplakin interacting protein
affects expression
ISO
Uranium affects the expression of KAZN mRNA
CTD
PMID:15672453
NCBI chr 4:141,829,701...142,801,231
Ensembl chr 4:141,829,701...142,205,056
G
Kdm2b
lysine (K)-specific demethylase 2B
affects expression
ISO
Uranium affects the expression of KDM2B mRNA
CTD
PMID:15672453
NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886
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Kdm4b
lysine (K)-specific demethylase 4B
increases expression
ISO
Uranium results in increased expression of KDM4B mRNA
CTD
PMID:15672453
NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870
G
Kdm5b
lysine demethylase 5B
affects expression
ISO
Uranium affects the expression of KDM5B mRNA
CTD
PMID:15672453
NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023
G
Kif1b
kinesin family member 1B
increases expression
ISO
Uranium results in increased expression of KIF1B mRNA
CTD
PMID:15672453
NCBI chr 4:149,260,776...149,392,762
Ensembl chr 4:149,260,776...149,392,150
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Kif3b
kinesin family member 3B
affects expression
ISO
Uranium affects the expression of KIF3B mRNA
CTD
PMID:15672453
NCBI chr 2:153,132,028...153,175,310
Ensembl chr 2:153,133,333...153,175,310
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Kif3c
kinesin family member 3C
affects expression
ISO
Uranium affects the expression of KIF3C mRNA
CTD
PMID:15672453
NCBI chr12:3,415,132...3,456,494
Ensembl chr12:3,415,132...3,456,494
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Kit
KIT proto-oncogene receptor tyrosine kinase
decreases expression
ISO
Uranium analog results in decreased expression of KIT mRNA
CTD
PMID:27544493
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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Kpna3
karyopherin subunit alpha 3
affects expression
ISO
Uranium affects the expression of KPNA3 mRNA
CTD
PMID:15672453
NCBI chr14:61,602,635...61,677,396
Ensembl chr14:61,602,660...61,677,323
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Lad1
ladinin
affects expression
ISO
Uranium affects the expression of LAD1 mRNA
CTD
PMID:15672453
NCBI chr 1:135,746,336...135,761,079
Ensembl chr 1:135,746,336...135,761,080
G
Lamp2
lysosomal-associated membrane protein 2
affects expression
ISO
Uranium affects the expression of LAMP2 mRNA
CTD
PMID:15672453
NCBI chr X:37,488,524...37,545,337
Ensembl chr X:37,490,234...37,545,331
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Ldha
lactate dehydrogenase A
affects expression
ISO
Uranium affects the expression of LDHA mRNA
CTD
PMID:15672453
NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
G
Lhb
luteinizing hormone beta
increases expression
ISO
Uranium analog results in increased expression of LHB protein
CTD
PMID:27544493
NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
decreases expression
ISO
Uranium analog results in decreased expression of LHCGR mRNA
CTD
PMID:27544493
NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
G
Lonp2
lon peptidase 2, peroxisomal
increases expression
ISO
Uranium results in increased expression of LONP2 mRNA
CTD
PMID:15672453
NCBI chr 8:87,350,672...87,443,264
Ensembl chr 8:87,350,672...87,450,501
G
Lpin1
lipin 1
affects expression
ISO
Uranium affects the expression of LPIN1 mRNA
CTD
PMID:15672453
NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
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M6pr
mannose-6-phosphate receptor, cation dependent
affects expression
ISO
Uranium affects the expression of M6PR mRNA
CTD
PMID:15672453
NCBI chr 6:122,285,679...122,294,639
Ensembl chr 6:122,285,679...122,294,639
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Maob
monoamine oxidase B
decreases expression
ISO
Uranium results in decreased expression of MAOB mRNA; Uranium results in decreased expression of MAOB protein
CTD
PMID:30076899
NCBI chr X:16,575,520...16,683,605
Ensembl chr X:16,575,521...16,683,605
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Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
increases expression multiple interactions
EXP
Uranium results in increased expression of MAP1LC3A protein bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
CTD
PMID:31120128
NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993
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Marcks
myristoylated alanine rich protein kinase C substrate
affects expression
ISO
Uranium affects the expression of MARCKS mRNA
CTD
PMID:15672453
NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916
G
Mat2b
methionine adenosyltransferase 2 non-catalytic beta subunit methionine
affects expression
ISO
Uranium affects the expression of MAT2B mRNA
CTD
PMID:15672453
NCBI chr11:40,570,141...40,586,030
Ensembl chr11:40,570,141...40,586,030
G
Mcfd2
multiple coagulation factor deficiency 2
affects expression
ISO
Uranium affects the expression of MCFD2 mRNA
CTD
PMID:15672453
NCBI chr17:87,561,871...87,573,382
Ensembl chr17:87,561,871...87,573,363
G
Mdh2
malate dehydrogenase 2, NAD (mitochondrial)
affects expression
ISO
Uranium affects the expression of MDH2 mRNA
CTD
PMID:15672453
NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
G
Metap2
methionine aminopeptidase 2
affects expression
ISO
Uranium affects the expression of METAP2 mRNA
CTD
PMID:15672453
NCBI chr10:93,694,351...93,732,952
Ensembl chr10:93,694,351...93,732,955
G
Mfsd4a
major facilitator superfamily domain containing 4A
affects expression
ISO
Uranium affects the expression of MFSD4A mRNA
CTD
PMID:15672453
NCBI chr 1:131,947,543...131,997,400
Ensembl chr 1:131,950,544...131,995,800
G
Micu1
mitochondrial calcium uptake 1
affects expression
ISO
Uranium affects the expression of MICU1 mRNA
CTD
PMID:15672453
NCBI chr10:59,538,385...59,699,956
Ensembl chr10:59,538,299...59,699,954
G
Mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
affects expression
ISO
Uranium affects the expression of MLLT10 mRNA
CTD
PMID:15672453
NCBI chr 2:18,059,971...18,217,201
Ensembl chr 2:18,060,048...18,217,199
G
Msh2
mutS homolog 2
affects expression
ISO
Uranium affects the expression of MSH2 mRNA
CTD
PMID:15672453
NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
G
Msrb1
methionine sulfoxide reductase B1
affects expression
ISO
Uranium affects the expression of MSRB1 mRNA
CTD
PMID:15672453
NCBI chr17:24,955,567...24,961,752
Ensembl chr17:24,955,616...24,961,752
G
Mt2
metallothionein 2
increases expression
ISO
Uranium results in increased expression of MT2A mRNA
CTD
PMID:14971665
NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
G
Nadk2
NAD kinase 2, mitochondrial
increases expression
ISO
Uranium results in increased expression of NADK2 mRNA
CTD
PMID:15672453
NCBI chr15:9,071,340...9,110,584
Ensembl chr15:9,071,340...9,110,979
G
Nae1
NEDD8 activating enzyme E1 subunit 1
affects expression
ISO
Uranium affects the expression of NAE1 mRNA
CTD
PMID:15672453
NCBI chr 8:105,237,660...105,261,269
Ensembl chr 8:105,237,660...105,261,269
G
Naip2
NLR family, apoptosis inhibitory protein 2
affects expression
ISO
Uranium affects the expression of NAIP mRNA
CTD
PMID:15672453
NCBI chr13:100,280,571...100,338,630
Ensembl chr13:100,280,571...100,338,600
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Nampt
nicotinamide phosphoribosyltransferase
affects expression
ISO
Uranium affects the expression of NAMPT mRNA
CTD
PMID:15672453
NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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Nap1l1
nucleosome assembly protein 1-like 1
affects expression
ISO
Uranium affects the expression of NAP1L1 mRNA
CTD
PMID:15672453
NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011
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Nars1
asparaginyl-tRNA synthetase 1
affects expression
ISO
Uranium affects the expression of NARS1 mRNA
CTD
PMID:15672453
NCBI chr18:64,632,726...64,649,586
Ensembl chr18:64,632,718...64,649,723
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Ncoa7
nuclear receptor coactivator 7
affects expression
ISO
Uranium affects the expression of NCOA7 mRNA
CTD
PMID:15672453
NCBI chr10:30,521,578...30,683,401
Ensembl chr10:30,504,995...30,679,322
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Ndfip1
Nedd4 family interacting protein 1
affects expression
ISO
Uranium affects the expression of NDFIP1 mRNA
CTD
PMID:15672453
NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356
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Ndrg2
N-myc downstream regulated gene 2
affects expression
ISO
Uranium affects the expression of NDRG2 mRNA
CTD
PMID:15672453
NCBI chr14:52,142,738...52,151,463
Ensembl chr14:52,142,728...52,151,615
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Ndrg4
N-myc downstream regulated gene 4
increases expression
ISO
Uranium results in increased expression of NDRG4 mRNA
CTD
PMID:15672453
NCBI chr 8:96,403,602...96,441,584
Ensembl chr 8:96,403,608...96,441,747
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Nefl
neurofilament, light polypeptide
affects expression
ISO
Uranium affects the expression of NEFL mRNA
CTD
PMID:15672453
NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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Neil2
nei like 2 (E. coli)
affects expression
ISO
Uranium affects the expression of NEIL2 mRNA
CTD
PMID:15672453
NCBI chr14:63,419,888...63,431,604
Ensembl chr14:63,419,892...63,431,305
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Nos2
nitric oxide synthase 2, inducible
decreases activity multiple interactions
ISO
Uranium results in decreased activity of NOS2 protein [[Uranium results in decreased activity of NOS2 protein] co-treated with [Uranium results in increased activity of NOS3 protein]] results in decreased abundance of Nitrates; [[Uranium results in decreased activity of NOS2 protein] co-treated with [Uranium results in increased activity of NOS3 protein]] results in decreased abundance of Nitrites
CTD
PMID:17566059
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Nos3
nitric oxide synthase 3, endothelial cell
multiple interactions increases activity decreases expression
ISO
[[Uranium results in decreased activity of NOS2 protein] co-treated with [Uranium results in increased activity of NOS3 protein]] results in decreased abundance of Nitrates; [[Uranium results in decreased activity of NOS2 protein] co-treated with [Uranium results in increased activity of NOS3 protein]] results in decreased abundance of Nitrites Uranium results in decreased expression of NOS3 mRNA
CTD
PMID:17566059
NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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Notch1
notch 1
decreases expression
ISO
Uranium results in decreased expression of NOTCH1 mRNA
CTD
PMID:27639536
NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
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Notch2
notch 2
affects expression
ISO
Uranium affects the expression of NOTCH2 mRNA
CTD
PMID:15672453
NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
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Npepl1
aminopeptidase-like 1
affects expression
ISO
Uranium affects the expression of NPEPL1 mRNA
CTD
PMID:15672453
NCBI chr 2:173,951,904...173,964,495
Ensembl chr 2:173,952,142...173,964,863
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Nqo1
NAD(P)H dehydrogenase, quinone 1
increases expression
ISO
Uranium results in increased expression of NQO1 mRNA
CTD
PMID:37270086
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nr1h2
nuclear receptor subfamily 1, group H, member 2
decreases expression
ISO
Uranium results in decreased expression of NR1H2 mRNA
CTD
PMID:17118558
NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
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Nr1h3
nuclear receptor subfamily 1, group H, member 3
increases expression
ISO
Uranium results in increased expression of NR1H3 mRNA
CTD
PMID:16231126
NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
increases expression
ISO
Uranium results in increased expression of NR1H4 mRNA
CTD
PMID:16231126
NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases expression
ISO
Uranium results in increased expression of NR1I2 mRNA
CTD
PMID:16039771
NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases expression
ISO
Uranium results in increased expression of NR1I3 mRNA
CTD
PMID:16039771 PMID:16231126
NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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Nrf1
nuclear respiratory factor 1
affects expression
ISO
Uranium affects the expression of NRF1 mRNA
CTD
PMID:15672453
NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
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Nsg2
neuron specific gene family member 2
affects expression
ISO
Uranium affects the expression of NSG2 mRNA
CTD
PMID:15672453
NCBI chr11:31,949,678...32,009,211
Ensembl chr11:31,950,463...32,009,202
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Nt5e
5' nucleotidase, ecto
affects expression
ISO
Uranium affects the expression of NT5E mRNA
CTD
PMID:15672453
NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
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Oat
ornithine aminotransferase
affects expression
ISO
Uranium affects the expression of OAT mRNA
CTD
PMID:15672453
NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
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Ocln
occludin
increases expression
ISO
Uranium analog results in increased expression of OCLN mRNA
CTD
PMID:27544493
NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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Paip2b
poly(A) binding protein interacting protein 2B
affects expression
ISO
Uranium affects the expression of PAIP2B mRNA
CTD
PMID:15672453
NCBI chr 6:83,783,040...83,808,723
Ensembl chr 6:83,782,383...83,808,723
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Parp4
poly (ADP-ribose) polymerase family, member 4
increases expression
ISO
Uranium results in increased expression of PARP4 mRNA
CTD
PMID:15672453
NCBI chr14:56,812,982...56,897,256
Ensembl chr14:56,813,076...56,897,251
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Pbx3
pre B cell leukemia homeobox 3
affects expression
ISO
Uranium affects the expression of PBX3 mRNA
CTD
PMID:15672453
NCBI chr 2:34,061,469...34,264,168
Ensembl chr 2:34,061,469...34,263,154
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Pdcd6ip
programmed cell death 6 interacting protein
affects expression
ISO
Uranium affects the expression of PDCD6IP mRNA
CTD
PMID:15672453
NCBI chr 9:113,480,812...113,537,457
Ensembl chr 9:113,480,812...113,537,327
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Pdcd7
programmed cell death 7
affects expression
ISO
Uranium affects the expression of PDCD7 mRNA
CTD
PMID:15672453
NCBI chr 9:65,253,350...65,266,925
Ensembl chr 9:65,253,386...65,266,925
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Pde1a
phosphodiesterase 1A, calmodulin-dependent
affects expression
ISO
Uranium affects the expression of PDE1A mRNA
CTD
PMID:15672453
NCBI chr 2:79,664,797...80,026,862
Ensembl chr 2:79,664,797...79,959,802
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Pdpn
podoplanin
increases expression
EXP
Uranium results in increased expression of PDPN protein
CTD
PMID:31120128
NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134
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Pfkfb4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
affects expression
ISO
Uranium affects the expression of PFKFB4 mRNA
CTD
PMID:15672453
NCBI chr 9:108,817,336...108,861,302
Ensembl chr 9:108,820,846...108,861,296
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Pgd
phosphogluconate dehydrogenase
affects expression
ISO
Uranium affects the expression of PGD mRNA
CTD
PMID:15672453
NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
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Phf10
PHD finger protein 10
affects expression
ISO
Uranium affects the expression of PHF10 mRNA
CTD
PMID:15672453
NCBI chr17:15,165,269...15,181,550
Ensembl chr17:15,165,271...15,181,535
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Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
affects expression
ISO
Uranium affects the expression of PI4K2A mRNA
CTD
PMID:15672453
NCBI chr19:42,078,590...42,110,657
Ensembl chr19:42,078,909...42,110,526
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
affects expression
ISO
Uranium affects the expression of PIK3R1 mRNA
CTD
PMID:15672453
NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
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Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
affects expression
ISO
Uranium affects the expression of PIP4K2B mRNA
CTD
PMID:15672453
NCBI chr11:97,605,983...97,635,530
Ensembl chr11:97,605,983...97,635,530
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Plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
affects expression
ISO
Uranium affects the expression of PLEKHB2 mRNA
CTD
PMID:15672453
NCBI chr 1:34,889,040...34,918,666
Ensembl chr 1:34,889,057...34,918,661
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Ppia
peptidylprolyl isomerase A
affects expression
ISO
Uranium affects the expression of PPIA mRNA
CTD
PMID:15672453
NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817
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Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
affects expression
ISO
Uranium affects the expression of PPP2CA mRNA
CTD
PMID:15672453
NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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Prdx2
peroxiredoxin 2
affects expression
ISO
Uranium affects the expression of PRDX2 mRNA
CTD
PMID:15672453
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
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Prpf4b
pre-mRNA processing factor 4B
affects expression
ISO
Uranium affects the expression of PRP4K mRNA
CTD
PMID:15672453
NCBI chr13:35,058,803...35,090,047
Ensembl chr13:35,059,285...35,090,047
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Psma4
proteasome subunit alpha 4
affects expression
ISO
Uranium affects the expression of PSMA4 mRNA
CTD
PMID:15672453
NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314
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Psmg1
proteasome (prosome, macropain) assembly chaperone 1
affects expression
ISO
Uranium affects the expression of PSMG1 mRNA
CTD
PMID:15672453
NCBI chr16:95,781,133...95,792,160
Ensembl chr16:95,781,133...95,792,160
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Ptges3
prostaglandin E synthase 3
affects expression
ISO
Uranium affects the expression of PTGES3 mRNA
CTD
PMID:15672453
NCBI chr10:127,894,851...127,913,123
Ensembl chr10:127,894,823...127,913,141
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Uranium results in increased expression of PTGS2
CTD
PMID:17566059
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Pth
parathyroid hormone
decreases expression increases expression
ISO
Uranium results in decreased expression of PTH protein Uranium results in increased expression of PTH protein
CTD
PMID:16436523 PMID:16502312
NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777
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Ptk2
PTK2 protein tyrosine kinase 2
affects expression
ISO
Uranium affects the expression of PTK2 mRNA
CTD
PMID:15672453
NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
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Ptma
prothymosin alpha
affects expression
ISO
Uranium affects the expression of PTMA mRNA
CTD
PMID:15672453
NCBI chr 1:86,454,442...86,458,434
Ensembl chr 1:86,454,448...86,458,434
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Pum1
pumilio RNA-binding family member 1
affects expression
ISO
Uranium affects the expression of PUM1 mRNA
CTD
PMID:15672453
NCBI chr 4:130,390,509...130,508,875
Ensembl chr 4:130,390,632...130,508,875
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Rab11fip4
RAB11 family interacting protein 4 (class II)
affects expression
ISO
Uranium affects the expression of RAB11FIP4 mRNA
CTD
PMID:15672453
NCBI chr11:79,481,847...79,588,842
Ensembl chr11:79,482,038...79,588,849
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Rab2a
RAB2A, member RAS oncogene family
affects expression
ISO
Uranium affects the expression of RAB2 mRNA
CTD
PMID:15672453
NCBI chr 4:8,535,661...8,607,708
Ensembl chr 4:8,535,644...8,607,778
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Rab7
RAB7, member RAS oncogene family
affects expression
ISO
Uranium affects the expression of RAB7 mRNA
CTD
PMID:15672453
NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252
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Rabggtb
Rab geranylgeranyl transferase, b subunit
affects expression
ISO
Uranium affects the expression of RABGGTB mRNA
CTD
PMID:15672453
NCBI chr 3:153,612,926...153,618,603
Ensembl chr 3:153,612,924...153,618,646
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Rac1
Rac family small GTPase 1
affects expression
ISO
Uranium affects the expression of RAC1 mRNA
CTD
PMID:15672453
NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
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Ran
RAN, member RAS oncogene family
affects expression
ISO
Uranium affects the expression of RAN mRNA
CTD
PMID:15672453
NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
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Rbbp7
retinoblastoma binding protein 7, chromatin remodeling factor
affects expression
ISO
Uranium affects the expression of RBBP7 mRNA
CTD
PMID:15672453
NCBI chr X:161,543,368...161,562,086
Ensembl chr X:161,543,398...161,562,088
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Rbm3
RNA binding motif (RNP1, RRM) protein 3
increases expression
ISO
Uranium results in increased expression of RBM3 mRNA
CTD
PMID:15672453
NCBI chr X:8,005,214...8,012,119
Ensembl chr X:8,005,214...8,012,119
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Rbm8a
RNA binding motif protein 8a
affects expression
ISO
Uranium affects the expression of RBM8A mRNA
CTD
PMID:15672453
NCBI chr 3:96,537,244...96,541,107
Ensembl chr 3:96,537,249...96,541,107
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Rdx
radixin
affects expression
ISO
Uranium affects the expression of RDX mRNA
CTD
PMID:15672453
NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
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Reep1
receptor accessory protein 1
affects expression
ISO
Uranium affects the expression of REEP1 mRNA
CTD
PMID:15672453
NCBI chr 6:71,684,413...71,787,694
Ensembl chr 6:71,684,545...71,787,694
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Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
affects expression
ISO
Uranium affects the expression of RGL mRNA
CTD
PMID:15672453
NCBI chr 1:152,392,513...152,642,056
Ensembl chr 1:152,392,511...152,642,102
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Rhoa
ras homolog family member A
affects expression
ISO
Uranium affects the expression of RHOA mRNA
CTD
PMID:15672453
NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
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Rhot1
ras homolog family member T1
affects expression
ISO
Uranium affects the expression of RHOT1 mRNA
CTD
PMID:15672453
NCBI chr11:80,099,844...80,158,736
Ensembl chr11:80,099,845...80,158,733
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Rmi1
RecQ mediated genome instability 1
affects expression
ISO
Uranium affects the expression of RMI1 mRNA
CTD
PMID:15672453
NCBI chr13:58,550,062...58,558,963
Ensembl chr13:58,550,062...58,558,962
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Rnf10
ring finger protein 10
affects expression
ISO
Uranium affects the expression of RNF10 mRNA
CTD
PMID:15672453
NCBI chr 5:115,379,829...115,410,951
Ensembl chr 5:115,379,471...115,410,957
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Rnf123
ring finger protein 123
affects expression
ISO
Uranium affects the expression of RNF123 mRNA
CTD
PMID:15672453
NCBI chr 9:107,928,869...107,957,183
Ensembl chr 9:107,928,733...107,960,545
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Rnf144a
ring finger protein 144A
affects expression
ISO
Uranium affects the expression of RNF144A mRNA
CTD
PMID:15672453
NCBI chr12:26,356,796...26,465,296
Ensembl chr12:26,350,963...26,465,253
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Rngtt
RNA guanylyltransferase and 5'-phosphatase
affects expression
ISO
Uranium affects the expression of RNGTT mRNA
CTD
PMID:15672453
NCBI chr 4:33,310,300...33,502,610
Ensembl chr 4:33,310,311...33,502,614
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Rpa1
replication protein A1
affects expression
ISO
Uranium affects the expression of RPA1 mRNA
CTD
PMID:15672453
NCBI chr11:75,191,085...75,239,478
Ensembl chr11:75,188,992...75,239,150
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Rpl15
ribosomal protein L15
affects expression
ISO
Uranium affects the expression of RPL15 mRNA
CTD
PMID:15672453
NCBI chr14:4,198,710...4,201,873
Ensembl chr14:4,198,305...4,201,873
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Rpl22
ribosomal protein L22
affects expression
ISO
Uranium affects the expression of RPL22 mRNA
CTD
PMID:15672453
NCBI chr 4:152,408,893...152,418,539
Ensembl chr 4:152,410,199...152,418,528
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Rpl24
ribosomal protein L24
affects expression
ISO
Uranium affects the expression of RPL24 mRNA
CTD
PMID:15672453
NCBI chr16:55,786,638...55,791,800
Ensembl chr16:55,786,638...55,791,798
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Rsl24d1
ribosomal L24 domain containing 1
affects expression
ISO
Uranium affects the expression of RSL24D1 mRNA
CTD
PMID:15672453
NCBI chr 9:73,020,751...73,030,615
Ensembl chr 9:73,020,708...73,030,615
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Rxra
retinoid X receptor alpha
decreases expression
ISO
Uranium results in decreased expression of RXRA mRNA
CTD
PMID:17118558
NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
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S100g
S100 calcium binding protein G
decreases expression increases expression
ISO
Uranium results in decreased expression of S100G mRNA Uranium results in increased expression of S100G mRNA
CTD
PMID:16502312
NCBI chr X:161,744,988...161,747,595
Ensembl chr X:161,744,988...161,747,595
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Scamp1
secretory carrier membrane protein 1
affects expression
ISO
Uranium affects the expression of SCAMP1 mRNA
CTD
PMID:15672453
NCBI chr13:94,337,818...94,422,339
Ensembl chr13:94,337,818...94,422,365
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Scn2b
sodium channel, voltage-gated, type II, beta
affects expression
ISO
Uranium affects the expression of SCN2B mRNA
CTD
PMID:15672453
NCBI chr 9:45,029,174...45,041,368
Ensembl chr 9:45,029,080...45,041,368
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Scp2
sterol carrier protein 2, liver
affects expression
ISO
Uranium affects the expression of SCP2 mRNA
CTD
PMID:15672453
NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195
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Sdc3
syndecan 3
affects expression
ISO
Uranium affects the expression of SDC3 mRNA
CTD
PMID:15672453
NCBI chr 4:130,519,855...130,553,629
Ensembl chr 4:130,519,848...130,553,630
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Sdcbp
syndecan binding protein
affects expression
ISO
Uranium affects the expression of SDCBP mRNA
CTD
PMID:15672453
NCBI chr 4:6,365,713...6,396,120
Ensembl chr 4:6,365,650...6,408,423
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Sec24b
SEC24 homolog B, COPII coat complex component
affects expression
ISO
Uranium affects the expression of SEC24B mRNA
CTD
PMID:15672453
NCBI chr 3:129,776,408...129,855,248
Ensembl chr 3:129,776,408...129,855,202
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Sec62
SEC62 homolog, preprotein translocation
affects expression
ISO
Uranium affects the expression of SEC62 mRNA
CTD
PMID:15672453
NCBI chr 3:30,847,025...30,875,412
Ensembl chr 3:30,847,024...30,875,412
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Selenoi
selenoprotein I
affects expression
ISO
Uranium affects the expression of SELENOI mRNA
CTD
PMID:15672453
NCBI chr 5:30,437,579...30,477,428
Ensembl chr 5:30,437,579...30,477,425
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Serbp1
serpine1 mRNA binding protein 1
affects expression
ISO
Uranium affects the expression of SERBP1 mRNA
CTD
PMID:15672453
NCBI chr 6:67,243,963...67,266,286
Ensembl chr 6:67,215,160...67,274,720
G
Sfxn3
sideroflexin 3
affects expression
ISO
Uranium affects the expression of SFXN3 mRNA
CTD
PMID:15672453
NCBI chr19:45,036,015...45,044,822
Ensembl chr19:45,035,942...45,044,822
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Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
decreases expression increases expression
ISO
Uranium results in decreased expression of SLC11A2 protein Uranium results in increased expression of SLC11A2 mRNA
CTD
PMID:18375546
NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
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Slc17a2
solute carrier family 17 (sodium phosphate), member 2
affects expression
ISO
Uranium affects the expression of SLC17A2 mRNA
CTD
PMID:15672453
NCBI chr13:23,990,924...24,009,174
Ensembl chr13:23,990,976...24,009,163
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Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
affects expression
ISO
Uranium affects the expression of SLC2A3 mRNA
CTD
PMID:15672453
NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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Slc34a1
solute carrier family 34 (sodium phosphate), member 1
multiple interactions
ISO
SLC34A1 protein results in increased uptake of [Uranium binds to Phosphates]
CTD
PMID:16476458
NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405
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Slc44a5
solute carrier family 44, member 5
affects expression
ISO
Uranium affects the expression of SLC44A5 mRNA
CTD
PMID:15672453
NCBI chr 3:153,679,056...153,977,384
Ensembl chr 3:153,679,073...153,977,359
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Slc8a1
solute carrier family 8 (sodium/calcium exchanger), member 1
decreases expression
ISO
Uranium results in decreased expression of SLC8A1 mRNA
CTD
PMID:17118558
NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806
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Smap1
small ArfGAP 1
affects expression
ISO
Uranium affects the expression of SMAP1 mRNA
CTD
PMID:15672453
NCBI chr 1:23,883,925...23,961,462
Ensembl chr 1:23,883,927...23,961,398
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Smarcc1
SWI/SNF related BAF chromatin remodeling complex subunit C1
affects expression
ISO
Uranium affects the expression of SMARCC1 mRNA
CTD
PMID:15672453
NCBI chr 9:109,961,129...110,069,773
Ensembl chr 9:109,946,776...110,069,246
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Smc5
structural maintenance of chromosomes 5
affects expression
ISO
Uranium affects the expression of SMC5 mRNA
CTD
PMID:15672453
NCBI chr19:23,183,817...23,251,286
Ensembl chr19:23,183,815...23,251,261
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Snap91
synaptosomal-associated protein 91
affects expression
ISO
Uranium affects the expression of SNAP91 mRNA
CTD
PMID:15672453
NCBI chr 9:86,647,976...86,762,766
Ensembl chr 9:86,647,976...86,762,707
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Snx6
sorting nexin 6
affects expression
ISO
Uranium affects the expression of SNX6 mRNA
CTD
PMID:15672453
NCBI chr12:54,793,124...54,842,464
Ensembl chr12:54,793,134...54,842,488
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Spatc1l
spermatogenesis and centriole associated 1 like
affects expression
ISO
Uranium affects the expression of SPATC1L mRNA
CTD
PMID:15672453
NCBI chr10:76,394,180...76,406,035
Ensembl chr10:76,398,106...76,406,035
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Spp1
secreted phosphoprotein 1
decreases secretion decreases expression
ISO EXP
Uranium results in decreased secretion of SPP1 protein Uranium results in decreased expression of SPP1 mRNA
CTD
PMID:21324525 PMID:31120128
NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
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Spp2
secreted phosphoprotein 2
affects expression
ISO
Uranium affects the expression of SPP2 mRNA
CTD
PMID:15672453
NCBI chr 1:88,334,688...88,356,022
Ensembl chr 1:88,334,683...88,354,160
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Srrm1
serine/arginine repetitive matrix 1
affects expression
ISO
Uranium affects the expression of SRRM1 mRNA
CTD
PMID:15672453
NCBI chr 4:135,047,795...135,080,787
Ensembl chr 4:135,047,795...135,080,632
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Ssx2ip
SSX family member 2 interacting protein
affects expression
ISO
Uranium affects the expression of SSX2IP mRNA
CTD
PMID:15672453
NCBI chr 3:146,110,397...146,145,899
Ensembl chr 3:146,110,397...146,145,899
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Star
steroidogenic acute regulatory protein
decreases expression
ISO
Uranium analog results in decreased expression of STAR mRNA
CTD
PMID:27544493
NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
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Stk36
serine/threonine kinase 36
affects expression
ISO
Uranium affects the expression of STK36 mRNA
CTD
PMID:15672453
NCBI chr 1:74,640,583...74,676,053
Ensembl chr 1:74,640,604...74,676,053
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Stmn1
stathmin 1
affects expression
ISO
Uranium affects the expression of STMN1 mRNA
CTD
PMID:15672453
NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
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Stmn2
stathmin-like 2
affects expression
ISO
Uranium affects the expression of STMN2 mRNA
CTD
PMID:15672453
NCBI chr 3:8,574,587...8,626,664
Ensembl chr 3:8,574,420...8,626,666
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Sult1b1
sulfotransferase family 1B, member 1
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in decreased expression of SULT1B1 mRNA
CTD
PMID:17126469
NCBI chr 5:87,661,186...87,686,054
Ensembl chr 5:87,661,198...87,686,054
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Taldo1
transaldolase 1
affects expression
ISO
Uranium affects the expression of TALDO1 mRNA
CTD
PMID:15672453
NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881
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Tdg
thymine DNA glycosylase
affects expression decreases expression
ISO
Uranium affects the expression of TDG mRNA Uranium results in decreased expression of TDG mRNA
CTD
PMID:15672453 PMID:29024790
NCBI chr10:82,465,649...82,486,633
Ensembl chr10:82,465,662...82,486,633
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Tet2
tet methylcytosine dioxygenase 2
decreases expression
ISO
Uranium results in decreased expression of TET2 mRNA
CTD
PMID:29024790
NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
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Tet3
tet methylcytosine dioxygenase 3
decreases expression
ISO
Uranium results in decreased expression of TET3 mRNA
CTD
PMID:29024790
NCBI chr 6:83,339,355...83,434,190
Ensembl chr 6:83,339,355...83,436,066
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Tfam
transcription factor A, mitochondrial
affects expression
ISO
Uranium affects the expression of TFAM mRNA
CTD
PMID:15672453
NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
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Tgfb1
transforming growth factor, beta 1
decreases expression
ISO
Uranium analog results in decreased expression of TGFB1 mRNA
CTD
PMID:27544493
NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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Tgif2
TGFB-induced factor homeobox 2
affects expression
ISO
Uranium affects the expression of TGIF2 mRNA
CTD
PMID:15672453
NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490
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Tgoln1
trans-golgi network protein
affects expression
ISO
Uranium affects the expression of TGOLN2 mRNA
CTD
PMID:15672453
NCBI chr 6:72,585,403...72,593,983
Ensembl chr 6:72,585,415...72,593,983
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Thbs1
thrombospondin 1
multiple interactions decreases expression
ISO
THBS1 protein inhibits the reaction [Uranium results in increased expression of CASP3 protein]; THBS1 protein inhibits the reaction [Uranium results in increased expression of DDIT3 protein]; THBS1 protein inhibits the reaction [Uranium results in increased expression of EIF2AK3 mRNA]; THBS1 protein inhibits the reaction [Uranium results in increased expression of EIF2AK3 protein]; Uranium results in decreased expression of and results in decreased secretion of THBS1 protein Uranium results in decreased expression of THBS1 mRNA
CTD
PMID:37270086
NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
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Them5
thioesterase superfamily member 5
decreases expression
ISO
Uranium results in decreased expression of THEM5 mRNA
CTD
PMID:37270086
NCBI chr 3:94,249,406...94,254,659
Ensembl chr 3:94,249,406...94,254,659
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Tlk1
tousled-like kinase 1
affects expression
ISO
Uranium affects the expression of TLK1 mRNA
CTD
PMID:15672453
NCBI chr 2:70,542,751...70,656,505
Ensembl chr 2:70,542,751...70,656,072
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Tmem230
transmembrane protein 230
affects expression
ISO
Uranium affects the expression of TMEM230 mRNA
CTD
PMID:15672453
NCBI chr 2:132,081,412...132,089,708
Ensembl chr 2:132,081,412...132,089,727
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Tnf
tumor necrosis factor
decreases expression decreases secretion
ISO EXP
Uranium results in decreased expression of TNF mRNA Uranium results in decreased secretion of TNF protein
CTD
PMID:17566059 PMID:23659960
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfrsf11b
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
multiple interactions
ISO EXP
GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]; Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein Anisomycin inhibits the reaction [GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]]; GHRL protein inhibits the reaction [Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein]; Uranium results in decreased expression of and results in decreased secretion of TNFRSF11B protein
CTD
PMID:29477364
NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
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Tnfrsf1b
tumor necrosis factor receptor superfamily, member 1b
affects expression
ISO
Uranium affects the expression of TNFRSF1B mRNA
CTD
PMID:15672453
NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
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Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
affects expression
ISO
Uranium affects the expression of TNFRSF9 mRNA
CTD
PMID:15672453
NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
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Tnfsf11
tumor necrosis factor (ligand) superfamily, member 11
multiple interactions
EXP ISO
Anisomycin inhibits the reaction [GHRL protein inhibits the reaction [Uranium results in increased expression of and results in increased secretion of TNFSF11 protein]]; GHRL protein inhibits the reaction [Uranium results in increased expression of and results in increased secretion of TNFSF11 protein]; Uranium results in increased expression of and results in increased secretion of TNFSF11 protein
CTD
PMID:29477364
NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
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Tnp1
transition protein 1
affects expression
ISO
Uranium affects the expression of TNP1 mRNA
CTD
PMID:15672453
NCBI chr 1:73,054,233...73,055,058
Ensembl chr 1:73,054,233...73,055,068
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Tnp2
transition protein 2
decreases expression
ISO
Uranium analog results in decreased expression of TNP2 mRNA
CTD
PMID:27544493
NCBI chr16:10,605,799...10,606,519
Ensembl chr16:10,605,800...10,606,524
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Tnpo1
transportin 1
affects expression
ISO
Uranium affects the expression of TNPO1 mRNA
CTD
PMID:15672453
NCBI chr13:98,975,527...99,062,851
Ensembl chr13:98,975,527...99,062,892
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Tomm20
translocase of outer mitochondrial membrane 20
affects expression
ISO
Uranium affects the expression of TOMM20 mRNA
CTD
PMID:15672453
NCBI chr 8:127,657,414...127,672,671
Ensembl chr 8:127,657,417...127,672,594
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Traj19
T cell receptor alpha joining 19
affects expression
ISO
Uranium affects the expression of COA1 mRNA
CTD
PMID:15672453
NCBI chr14:54,437,843...54,437,903
Ensembl chr14:54,437,843...54,437,903
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Trak2
trafficking protein, kinesin binding 2
affects expression
ISO
Uranium affects the expression of TRAK2 mRNA
CTD
PMID:15672453
NCBI chr 1:58,939,608...59,013,509
Ensembl chr 1:58,939,608...59,012,589
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Trf
transferrin
multiple interactions
ISO
Uranium binds to and results in decreased stability of TF protein
CTD
PMID:17266333
NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
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Trim28
tripartite motif-containing 28
affects expression
ISO
Uranium affects the expression of TRIM28 mRNA
CTD
PMID:15672453
NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962
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Trpv5
transient receptor potential cation channel, subfamily V, member 5
increases expression decreases expression
ISO
Uranium results in increased expression of TRPV5 mRNA Uranium results in decreased expression of TRPV5 mRNA
CTD
PMID:16502312 PMID:17118558
NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
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Tuba1a
tubulin, alpha 1A
affects expression
ISO
Uranium affects the expression of TUBA1A mRNA
CTD
PMID:15672453
NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584
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Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
affects expression
ISO
Uranium affects the expression of UBE2D2 mRNA
CTD
PMID:15672453
NCBI chr18:35,904,612...35,940,225
Ensembl chr18:35,904,611...35,942,547
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
multiple interactions
ISO
[Acetaminophen co-treated with Uranium analog] results in decreased expression of UGT2B1 mRNA
CTD
PMID:17126469
NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
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Ulk2
unc-51 like kinase 2
affects expression
ISO
Uranium affects the expression of ULK2 mRNA
CTD
PMID:15672453
NCBI chr11:61,666,424...61,750,754
Ensembl chr11:61,666,475...61,745,899
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Ung
uracil DNA glycosylase
affects expression
ISO
Uranium affects the expression of UNG mRNA
CTD
PMID:15672453
NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
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Vdac2
voltage-dependent anion channel 2
affects expression
ISO
Uranium affects the expression of VDAC2 mRNA
CTD
PMID:15672453
NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
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Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
decreases expression
ISO
Uranium results in decreased expression of VDR mRNA
CTD
PMID:17118558
NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
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Vps13b
vacuolar protein sorting 13B
affects expression
ISO
Uranium affects the expression of VPS13B mRNA
CTD
PMID:15672453
NCBI chr15:35,371,264...35,931,375
Ensembl chr15:35,371,306...35,931,375
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Vps13d
vacuolar protein sorting 13D
affects expression
ISO
Uranium affects the expression of VPS13D mRNA
CTD
PMID:15672453
NCBI chr 4:144,597,619...144,921,598
Ensembl chr 4:144,699,192...144,921,575
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Vps26b
VPS26 retromer complex component B
affects expression
ISO
Uranium affects the expression of VPS26B mRNA
CTD
PMID:15672453
NCBI chr 9:26,915,798...26,941,390
Ensembl chr 9:26,919,067...26,941,361
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Vsnl1
visinin-like 1
affects expression
ISO
Uranium affects the expression of VSNL1 mRNA
CTD
PMID:15672453
NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
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Vta1
vesicle (multivesicular body) trafficking 1
affects expression
ISO
Uranium affects the expression of VTA1 mRNA
CTD
PMID:15672453
NCBI chr10:14,531,077...14,581,233
Ensembl chr10:14,530,499...14,581,304
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Wasl
WASP like actin nucleation promoting factor
affects expression
ISO
Uranium affects the expression of WASL mRNA
CTD
PMID:15672453
NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008
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Wdr59
WD repeat domain 59
affects expression
ISO
Uranium affects the expression of WDR59 mRNA
CTD
PMID:15672453
NCBI chr 8:112,175,413...112,248,760
Ensembl chr 8:112,175,429...112,248,724
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Wfdc2
WAP four-disulfide core domain 2
affects expression
ISO
Uranium affects the expression of WFDC2 mRNA
CTD
PMID:15672453
NCBI chr 2:164,404,635...164,410,430
Ensembl chr 2:164,404,333...164,410,430
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Wnt3a
wingless-type MMTV integration site family, member 3A
decreases expression
ISO
Uranium results in decreased expression of WNT3A mRNA
CTD
PMID:27639536
NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
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Wnt7b
wingless-type MMTV integration site family, member 7B
affects expression
ISO
Uranium affects the expression of WNT7B mRNA
CTD
PMID:15672453
NCBI chr15:85,419,638...85,466,022
Ensembl chr15:85,419,638...85,466,674
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Wsb2
WD repeat and SOCS box-containing 2
affects expression
ISO
Uranium affects the expression of WSB2 mRNA
CTD
PMID:15672453
NCBI chr 5:117,495,370...117,516,666
Ensembl chr 5:117,495,369...117,516,666
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Wt1os
WT1 transcription factor, opposite strand
affects expression
ISO
Uranium affects the expression of WT1-AS mRNA
CTD
PMID:15672453
NCBI chr 2:104,906,883...104,956,855
Ensembl chr 2:104,906,883...104,956,913
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Ythdf3
YTH N6-methyladenosine RNA binding protein 3
affects expression
ISO
Uranium affects the expression of YTHDF3 mRNA
CTD
PMID:15672453
NCBI chr 3:16,237,309...16,271,201
Ensembl chr 3:16,237,376...16,271,201
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Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
affects expression
ISO
Uranium affects the expression of YWHAB protein
CTD
PMID:15672453
NCBI chr 2:163,837,082...163,860,508
Ensembl chr 2:163,836,880...163,860,508
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Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
affects expression
ISO
Uranium affects the expression of YWHAQ mRNA
CTD
PMID:15672453
NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638
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Zbtb16
zinc finger and BTB domain containing 16
increases expression
ISO
Uranium results in increased expression of ZBTB16 mRNA
CTD
PMID:37270086
NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522
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Zfp82
zinc finger protein 82
affects expression
ISO
Uranium affects the expression of ZFP82 mRNA
CTD
PMID:15672453
NCBI chr 7:29,755,459...29,772,248
Ensembl chr 7:29,753,914...29,772,325
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