Actr2 (actin related protein 2) - Rat Genome Database

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Gene: Actr2 (actin related protein 2) Mus musculus
Analyze
Symbol: Actr2
Name: actin related protein 2
RGD ID: 1321953
MGI Page MGI
Description: Predicted to enable cytoskeletal protein binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cellular response to type II interferon; meiotic chromosome movement towards spindle pole; and meiotic cytokinesis. Located in actin cap. Is expressed in cochlea and metanephros. Orthologous to human ACTR2 (actin related protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4921510D23Rik; A; AA409782; actin-like protein 2; actin-related protein 2; Arp2; ARP2 actin-related protein 2; ARP2 actin-related protein 2 homolog; D6Ertd746; D6Ertd746e; MGC36604
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm6828   Gm9729  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,012,304 - 20,062,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,012,304 - 20,062,913 (-)EnsemblGRCm39 Ensembl
GRCm381120,062,304 - 20,112,951 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,062,304 - 20,112,913 (-)EnsemblGRCm38mm10GRCm38
MGSCv371119,962,307 - 20,012,954 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361119,962,307 - 20,012,915 (-)NCBIMGSCv36mm8
Celera1122,204,487 - 22,259,500 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,8-cineole  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
aluminium oxide  (EXP)
amitrole  (ISO)
Aroclor 1254  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
D-glucose  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP,ISO)
ethanol  (ISO)
folic acid  (EXP)
fumonisin B1  (EXP)
geldanamycin  (ISO)
gentamycin  (ISO)
glucose  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
nickel atom  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
rimonabant  (EXP)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. Chiu TT, etal., Mol Biol Cell. 2010 Oct 15;21(20):3529-39. doi: 10.1091/mbc.E10-04-0316. Epub 2010 Aug 25.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes. Miao J, etal., Nephrol Dial Transplant. 2009 Nov;24(11):3297-305. doi: 10.1093/ndt/gfp338. Epub 2009 Jul 17.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Involvement of Arp2/3 complex in the process of colorectal carcinogenesis. Otsubo T, etal., Mod Pathol. 2004 Apr;17(4):461-7.
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted. Vyas A, etal., J Comp Neurol 2003 Nov 24;466(4):545-53.
11. Relationship between learning and memory deficits and Arp2 expression in the hippocampus in rats with traumatic brain injury. Xia X, etal., World Neurosurg. 2012 Dec;78(6):689-96. doi: 10.1016/j.wneu.2011.07.042. Epub 2011 Nov 7.
12. Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis. Zhao H, etal., Front Immunol. 2023 Sep 4;14:1197752. doi: 10.3389/fimmu.2023.1197752. eCollection 2023.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12589062   PMID:12904583   PMID:14610273   PMID:15085951   PMID:15233919   PMID:15247266  
PMID:15331365   PMID:15489334   PMID:15747579   PMID:16141072   PMID:16141073   PMID:17500055   PMID:17721515   PMID:17967808   PMID:18720401   PMID:18799693   PMID:19068115   PMID:19144319  
PMID:19922875   PMID:21406566   PMID:21494665   PMID:21677750   PMID:21873635   PMID:21874009   PMID:22385962   PMID:22684256   PMID:22951093   PMID:23439682   PMID:23495010   PMID:24043783  
PMID:24457600   PMID:24998208   PMID:25220164   PMID:25315346   PMID:25737280   PMID:25926623   PMID:26028144   PMID:26370502   PMID:26655834   PMID:26975831   PMID:27181356   PMID:27927957  
PMID:28378742   PMID:28827327   PMID:29111324   PMID:29518331   PMID:30068389   PMID:30457570   PMID:30550785   PMID:30562941   PMID:30833597   PMID:31146259   PMID:31157616   PMID:31577955  
PMID:31815664   PMID:31961823   PMID:32079655   PMID:32325033   PMID:32554809   PMID:32581705   PMID:32968282   PMID:33903241   PMID:34455539   PMID:35658973   PMID:36293380   PMID:37142655  


Genomics

Comparative Map Data
Actr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,012,304 - 20,062,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,012,304 - 20,062,913 (-)EnsemblGRCm39 Ensembl
GRCm381120,062,304 - 20,112,951 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,062,304 - 20,112,913 (-)EnsemblGRCm38mm10GRCm38
MGSCv371119,962,307 - 20,012,954 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361119,962,307 - 20,012,915 (-)NCBIMGSCv36mm8
Celera1122,204,487 - 22,259,500 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.88NCBI
ACTR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38265,227,831 - 65,271,253 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl265,227,788 - 65,271,253 (+)EnsemblGRCh38hg38GRCh38
GRCh37265,454,965 - 65,498,387 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,308,406 - 65,351,891 (+)NCBINCBI36Build 36hg18NCBI36
Build 34265,366,552 - 65,410,036NCBI
Celera265,301,566 - 65,345,120 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef265,189,074 - 65,232,629 (+)NCBIHuRef
CHM1_1265,386,192 - 65,429,751 (+)NCBICHM1_1
T2T-CHM13v2.0265,237,506 - 65,280,921 (+)NCBIT2T-CHM13v2.0
Actr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,500,119 - 98,535,092 (-)NCBIGRCr8
mRatBN7.21494,296,443 - 94,333,735 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,296,443 - 94,340,524 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,639,283 - 98,680,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01499,879,572 - 99,920,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,346,941 - 96,387,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,338,486 - 104,375,840 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,340,434 - 104,375,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,072,596 - 104,109,950 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,848,391 - 100,883,833 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114100,867,618 - 100,903,044 (-)NCBI
Celera1493,318,648 - 93,356,930 (-)NCBICelera
Cytogenetic Map14q22NCBI
Actr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,293,949 - 19,333,170 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542419,293,949 - 19,333,170 (-)NCBIChiLan1.0ChiLan1.0
ACTR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21261,131,388 - 61,179,542 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A61,135,339 - 61,180,922 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,289,675 - 65,333,219 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,412,786 - 66,456,857 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,413,011 - 66,456,857 (+)Ensemblpanpan1.1panPan2
ACTR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,696,068 - 64,733,027 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,696,111 - 64,730,553 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1064,582,083 - 64,619,025 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01065,705,072 - 65,742,073 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,705,085 - 65,742,062 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,383,665 - 65,420,656 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,691,644 - 65,728,572 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,986,809 - 66,023,812 (+)NCBIUU_Cfam_GSD_1.0
Actr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,549,870 - 18,591,068 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364919,979,427 - 10,022,043 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364919,980,228 - 10,021,417 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,691,280 - 76,729,252 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1376,691,275 - 76,729,269 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,487,347 - 80,525,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACTR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,740,432 - 41,780,045 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1441,739,968 - 41,779,964 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604570,111,314 - 70,152,221 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,281,433 - 8,339,830 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247628,282,415 - 8,339,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Actr2
2071 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:914
Count of miRNA genes:524
Interacting mature miRNAs:625
Transcripts:ENSMUST00000000137, ENSMUST00000132022, ENSMUST00000134779
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
MDB0504  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381120,062,374 - 20,062,484UniSTSGRCm38
MGSCv371119,962,377 - 19,962,487UniSTSGRCm37
Celera1122,204,557 - 22,204,667UniSTS
Cytogenetic Map11A3.1UniSTS
Whitehead_YAC11 UniSTS
RH125883  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381120,062,366 - 20,062,615UniSTSGRCm38
MGSCv371119,962,369 - 19,962,618UniSTSGRCm37
Celera1122,204,549 - 22,204,798UniSTS
Cytogenetic Map11A3.1UniSTS
Whitehead/MRC_RH11381.6UniSTS
D6Ertd746e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A3.1UniSTS
cM Map631.5UniSTS
cM Map6 UniSTS
cM Map1131.5UniSTS
RH141392  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381197,161,710 - 97,161,908UniSTSGRCm38
MGSCv371197,023,024 - 97,023,222UniSTSGRCm37
Celera1122,261,026 - 22,261,224UniSTS
Celera11106,814,630 - 106,814,828UniSTS
Cytogenetic Map11A3.1UniSTS
Cytogenetic Map11DUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000000137   ⟹   ENSMUSP00000000137
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,012,304 - 20,062,913 (-)Ensembl
GRCm38.p6 Ensembl1120,062,304 - 20,112,913 (-)Ensembl
Ensembl Acc Id: ENSMUST00000132022
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,028,686 - 20,062,867 (-)Ensembl
GRCm38.p6 Ensembl1120,078,686 - 20,112,867 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134779
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,050,587 - 20,062,909 (-)Ensembl
GRCm38.p6 Ensembl1120,100,587 - 20,112,909 (-)Ensembl
RefSeq Acc Id: NM_001362899   ⟹   NP_001349828
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,012,304 - 20,062,951 (-)NCBI
GRCm381120,062,304 - 20,112,951 (-)NCBI
Sequence:
RefSeq Acc Id: NM_146243   ⟹   NP_666355
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,012,304 - 20,062,951 (-)NCBI
GRCm381120,062,304 - 20,112,951 (-)ENTREZGENE
MGSCv371119,962,307 - 20,012,954 (-)RGD
Celera1122,204,487 - 22,259,500 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666355   ⟸   NM_146243
- Peptide Label: isoform 2
- UniProtKB: Q6PI31 (UniProtKB/Swiss-Prot),   P61161 (UniProtKB/Swiss-Prot),   Q5SW83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001349828   ⟸   NM_001362899
- Peptide Label: isoform 1
Ensembl Acc Id: ENSMUSP00000000137   ⟸   ENSMUST00000000137

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61161-F1-model_v2 AlphaFold P61161 1-394 view protein structure

Promoters
RGD ID:6820281
Promoter ID:MM_KWN:6558
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_146243_ACTR2,   OTTMUST00000011647,   OTTMUST00000011649,   UC007ICS.1,   UC007ICT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361120,012,426 - 20,013,227 (-)MPROMDB
RGD ID:8674046
Promoter ID:EPDNEW_M15053
Type:initiation region
Name:Actr2_1
Description:Mus musculus ARP2 actin-related protein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381120,112,887 - 20,112,947EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913963 AgrOrtholog
Ensembl Genes ENSMUSG00000020152 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000000137 ENTREZGENE
  ENSMUST00000000137.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Actin/actin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66713 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913963 ENTREZGENE
NCBI Gene 66713 ENTREZGENE
PANTHER ACTIN-RELATED PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11937 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Actr2 PhenoGen
PRINTS ACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ACTINS_ACT_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ARP2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5SW83 ENTREZGENE, UniProtKB/TrEMBL
  Q6PI31 ENTREZGENE
UniProt Secondary O15142 UniProtKB/Swiss-Prot
  Q6PI31 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-12-19 Actr2  actin related protein 2  Actr2  ARP2 actin-related protein 2  Symbol and/or name change 5135510 APPROVED
2012-07-10 Actr2  ARP2 actin-related protein 2  Actr2  ARP2 actin-related protein 2 homolog (yeast)  Symbol and/or name change 5135510 APPROVED