Wnt3a (wingless-type MMTV integration site family, member 3A) - Rat Genome Database

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Gene: Wnt3a (wingless-type MMTV integration site family, member 3A) Mus musculus
Analyze
Symbol: Wnt3a
Name: wingless-type MMTV integration site family, member 3A
RGD ID: 1317607
MGI Page MGI
Description: Enables protein domain specific binding activity; signaling receptor binding activity; and transcription coactivator activity. Involved in several processes, including COP9 signalosome assembly; nervous system development; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and positive regulation of cell population proliferation. Located in cell surface and extracellular space. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; reproductive system; and urethra. Orthologous to human WNT3A (Wnt family member 3A); PARTICIPATES IN Wnt signaling, canonical pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: vestigial tail; vt; wingless-related MMTV integration site 3A; Wnt-; Wnt-3a
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm39 Ensembl1159,138,859 - 59,181,578 (-)Ensembl
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (TAS)
anterior/posterior pattern specification  (IDA)
axis elongation involved in somitogenesis  (IGI)
axon guidance  (IDA)
axonogenesis  (IDA,IGI)
BMP signaling pathway  (ISO)
calcium ion transmembrane transport via low voltage-gated calcium channel  (IDA)
canonical Wnt signaling pathway  (IBA,IDA,IGI,IMP,ISO)
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment  (ISO)
cardiac muscle cell fate commitment  (IGI)
cell fate commitment  (IBA)
cell population proliferation  (ISO)
cell proliferation in forebrain  (IDA)
cell proliferation in midbrain  (IDA)
cell-cell signaling  (TAS)
cellular protein localization  (IDA)
COP9 signalosome assembly  (IDA)
determination of left/right symmetry  (IMP)
dopaminergic neuron differentiation  (TAS)
dorsal/ventral neural tube patterning  (IMP)
extracellular matrix organization  (IDA)
heart looping  (IMP)
hemopoiesis  (IDA)
hippocampus development  (IMP)
in utero embryonic development  (IMP)
inner ear morphogenesis  (IGI)
mammary gland development  (IDA)
mesoderm development  (IMP)
midbrain development  (IDA)
modulation of chemical synaptic transmission  (EXP,IDA,IMP)
negative regulation of axon extension involved in axon guidance  (IDA)
negative regulation of dopaminergic neuron differentiation  (IDA)
negative regulation of fat cell differentiation  (IDA,IGI)
negative regulation of heart induction by canonical Wnt signaling pathway  (ISO)
negative regulation of neurogenesis  (IDA)
negative regulation of neuron death  (IGI)
negative regulation of neuron projection development  (IDA)
neurogenesis  (IDA)
neuron differentiation  (IBA)
osteoblast differentiation  (IGI)
paraxial mesodermal cell fate commitment  (IMP)
platelet activation  (IDA)
platelet aggregation  (IDA)
positive regulation of B cell proliferation  (IDA)
positive regulation of canonical Wnt signaling pathway  (IDA,ISO)
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation  (IDA)
positive regulation of cardiac muscle cell differentiation  (ISO)
positive regulation of cell population proliferation  (IDA)
positive regulation of cell-cell adhesion mediated by cadherin  (IDA)
positive regulation of collateral sprouting in absence of injury  (IDA)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
positive regulation of cytokine production  (IDA)
positive regulation of dermatome development  (ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of gene expression  (ISO)
positive regulation of hepatocyte proliferation  (IDA)
positive regulation of mesodermal cell fate specification  (ISO)
positive regulation of neural precursor cell proliferation  (IDA)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein binding  (ISO)
positive regulation of protein kinase activity  (IDA)
positive regulation of protein localization to plasma membrane  (IDA)
positive regulation of protein phosphorylation  (IDA,ISO)
positive regulation of protein tyrosine kinase activity  (IGI)
positive regulation of receptor internalization  (ISO)
positive regulation of skeletal muscle tissue development  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,ISO,NAS)
positive regulation of transcription, DNA-templated  (IDA)
post-anal tail morphogenesis  (IMP)
postsynapse to nucleus signaling pathway  (EXP,IDA)
regulation of axonogenesis  (IGI)
regulation of cell differentiation  (IDA)
regulation of microtubule cytoskeleton organization  (IGI)
regulation of presynapse assembly  (ISO)
regulation of RNA biosynthetic process  (IDA)
regulation of synapse organization  (ISO)
secondary palate development  (ISO)
signal transduction  (TAS)
skeletal muscle cell differentiation  (IGI)
somatic stem cell division  (IDA)
somitogenesis  (IMP)
spinal cord association neuron differentiation  (IDA,IGI)
Wnt signaling pathway  (IGI)
Wnt signaling pathway involved in forebrain neuroblast division  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone ossification  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal cortical marginal zone morphology  (IAGP)
abnormal dermomyotome development  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal forebrain development  (IAGP)
abnormal gastrulation  (IAGP)
abnormal heart morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal melanoblast morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal metencephalon morphology  (IAGP)
abnormal midbrain development  (IAGP)
abnormal myotome development  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural tube morphology  (IEA)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal somite development  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal tail bud morphology  (IEA)
abnormal tail morphology  (IEA)
abnormal tailgut morphology  (IEA)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thyroid cartilage morphology  (IAGP)
abnormal urination  (IAGP)
abnormal vertebrae morphology  (IAGP)
absent Cajal-Retzius cell  (IAGP)
absent choroid plexus  (IAGP)
absent hindlimb  (IAGP)
absent hyoid bone  (IAGP)
absent sacral vertebrae  (IAGP)
absent stapes  (IAGP)
absent tail  (IAGP)
absent tail bud  (IAGP)
caudal body truncation  (IAGP)
cervical vertebral transformation  (IAGP)
cleft palate  (IAGP)
decreased body length  (IAGP)
decreased Cajal-Retzius cell number  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased embryo size  (IAGP)
decreased lumbar vertebrae number  (IAGP)
decreased thoracic vertebrae number  (IAGP)
decreased ventral ectodermal ridge size  (IEA)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
failure of somite differentiation  (IAGP)
hindlimb paralysis  (IAGP)
incomplete somite formation  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lumbar vertebral transformation  (IAGP)
postnatal lethality  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
sacral vertebral transformation  (IAGP)
short mandible  (IAGP)
sirenomelia  (IAGP)
small alisphenoid bone  (IAGP)
small basisphenoid bone  (IAGP)
small dorsal root ganglion  (IAGP)
small otic capsule  (IAGP)
small presphenoid bone  (IAGP)
small temporal bone squamous part  (IAGP)
spina bifida  (IAGP)
thoracic vertebral transformation  (IAGP)
truncated notochord  (IAGP)
ventricular septal defect  (IAGP)
vestigial tail  (IAGP)
References

Additional References at PubMed
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PMID:30084950   PMID:30139740   PMID:30189017   PMID:30220568   PMID:30228991   PMID:30256721   PMID:30347193   PMID:30459452   PMID:30485816   PMID:30548789   PMID:30550847   PMID:30559277  
PMID:30622240   PMID:30651295   PMID:30664649   PMID:30692221   PMID:30879996   PMID:30894540   PMID:30940800   PMID:30953627   PMID:31119171   PMID:31147591   PMID:31167144   PMID:31222549  
PMID:31235634   PMID:31257105   PMID:31308417   PMID:31647919   PMID:31727925   PMID:31729356   PMID:31884387   PMID:31891351   PMID:32012381   PMID:32098078   PMID:32156757   PMID:32253237  
PMID:32597756   PMID:32616667   PMID:32703236   PMID:32755451   PMID:32822074   PMID:32855167   PMID:32969478   PMID:32994168   PMID:33060832   PMID:33141892   PMID:33153107   PMID:33246067  
PMID:33283877   PMID:33932339   PMID:33947861   PMID:34028355   PMID:34157307   PMID:34170322   PMID:34197726   PMID:34642323  


Genomics

Comparative Map Data
Wnt3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm39 Ensembl1159,138,859 - 59,181,578 (-)Ensembl
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
WNT3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1228,006,998 - 228,061,271 (+)EnsemblGRCh38hg38GRCh38
GRCh381228,006,998 - 228,067,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,194,699 - 228,248,972 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,261,375 - 226,315,584 (+)NCBINCBI36hg18NCBI36
Build 341224,501,486 - 224,555,696NCBI
Celera1201,384,988 - 201,439,196 (+)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1198,726,487 - 198,764,776 (+)NCBIHuRef
CHM1_11229,467,104 - 229,521,343 (+)NCBICHM1_1
Wnt3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21044,034,174 - 44,078,463 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1044,034,194 - 44,078,324 (-)Ensembl
Rnor_6.01045,598,898 - 45,643,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,598,912 - 45,638,035 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01045,354,369 - 45,398,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,553,682 - 45,594,983 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,567,304 - 45,609,958 (-)NCBI
Celera1043,297,443 - 43,336,315 (-)NCBICelera
Cytogenetic Map10q22NCBI
Wnt3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955581350,889 - 382,541 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955581351,375 - 382,541 (-)NCBIChiLan1.0ChiLan1.0
WNT3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11208,628,706 - 208,674,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1208,628,706 - 208,674,469 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01203,409,294 - 203,463,214 (+)NCBIMhudiblu_PPA_v0panPan3
WNT3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.114864,393 - 899,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl14863,424 - 896,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha14241,282 - 287,493 (+)NCBI
ROS_Cfam_1.014584,578 - 630,800 (-)NCBI
UMICH_Zoey_3.114775,380 - 821,576 (-)NCBI
UNSW_CanFamBas_1.014556,162 - 602,358 (-)NCBI
UU_Cfam_GSD_1.014542,112 - 590,168 (-)NCBI
Wnt3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721387,809,460 - 87,851,090 (-)NCBI
SpeTri2.0NW_004936864150,742 - 179,205 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,154,086 - 51,202,176 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,153,978 - 51,203,678 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,908,485 - 53,958,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,664,316 - 1,675,006 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660551,547,656 - 1,601,952 (-)NCBIVero_WHO_p1.0
Wnt3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937816,752 - 845,866 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,104 - 59,249,647UniSTSGRCm38
MGSCv371159,062,606 - 59,063,149UniSTSGRCm37
Celera1164,014,105 - 64,014,648UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
PMC26484P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,229 - 59,249,541UniSTSGRCm38
MGSCv371159,062,731 - 59,063,043UniSTSGRCm37
Celera1164,014,230 - 64,014,542UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,988UniSTSGRCm38
MGSCv371159,061,652 - 59,062,490UniSTSGRCm37
Celera1164,013,151 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,657 - 59,248,975UniSTSGRCm38
MGSCv371159,062,159 - 59,062,477UniSTSGRCm37
Celera1164,013,658 - 64,013,976UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,554 - 59,249,087UniSTSGRCm38
MGSCv371159,062,056 - 59,062,589UniSTSGRCm37
Celera1164,013,555 - 64,014,088UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,376UniSTSGRCm38
MGSCv371159,061,652 - 59,061,878UniSTSGRCm37
Celera1164,013,151 - 64,013,377UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,827 - 59,248,988UniSTSGRCm38
MGSCv371159,062,329 - 59,062,490UniSTSGRCm37
Celera1164,013,828 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir16-2mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir16-1mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pOncomiRDBexternal_infoNANA21106054

Predicted Target Of
Summary Value
Count of predictions:686
Count of miRNA genes:416
Interacting mature miRNAs:492
Transcripts:ENSMUST00000010044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000010044   ⟹   ENSMUSP00000010044
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1159,138,859 - 59,181,578 (-)Ensembl
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)Ensembl
RefSeq Acc Id: NM_009522   ⟹   NP_033548
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391159,138,862 - 59,181,577 (-)NCBI
GRCm381159,248,036 - 59,290,751 (-)ENTREZGENE
MGSCv371159,061,538 - 59,104,253 (-)RGD
Celera1164,013,041 - 64,056,135 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033548 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA40173 (Get FASTA)   NCBI Sequence Viewer  
  CAI38662 (Get FASTA)   NCBI Sequence Viewer  
  EDL07662 (Get FASTA)   NCBI Sequence Viewer  
  P27467 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033548   ⟸   NM_009522
- Peptide Label: precursor
- UniProtKB: P27467 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000010044   ⟸   ENSMUST00000010044

Promoters
RGD ID:8674820
Promoter ID:EPDNEW_M15434
Type:initiation region
Name:Wnt3a_1
Description:Mus musculus wingless-type MMTV integration site family, member3A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381159,290,753 - 59,290,813EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98956 AgrOrtholog
Ensembl Genes ENSMUSG00000009900 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.2460.20 UniProtKB/Swiss-Prot
InterPro Wnt UniProtKB/Swiss-Prot
  Wnt3 UniProtKB/Swiss-Prot
  Wnt_C UniProtKB/Swiss-Prot
  Wnt_CS UniProtKB/Swiss-Prot
KEGG Report mmu:22416 UniProtKB/Swiss-Prot
MGD MGI:98956 ENTREZGENE
NCBI Gene 22416 ENTREZGENE
PANTHER PTHR12027 UniProtKB/Swiss-Prot
Pfam wnt UniProtKB/Swiss-Prot
PhenoGen Wnt3a PhenoGen
PRINTS WNT3PROTEIN UniProtKB/Swiss-Prot
  WNTPROTEIN UniProtKB/Swiss-Prot
PROSITE WNT1 UniProtKB/Swiss-Prot
SMART WNT1 UniProtKB/Swiss-Prot
UniProt P27467 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 Wnt3a  wingless-type MMTV integration site family, member 3A    wingless-related MMTV integration site 3A  Symbol and/or name change 5135510 APPROVED