Wnt3a (wingless-type MMTV integration site family, member 3A) - Rat Genome Database
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Gene: Wnt3a (wingless-type MMTV integration site family, member 3A) Mus musculus
Analyze
Symbol: Wnt3a
Name: wingless-type MMTV integration site family, member 3A
RGD ID: 1317607
MGI Page MGI
Description: Exhibits frizzled binding activity; molecular function regulator; and protein domain specific binding activity. Involved in several processes, including animal organ development; nervous system development; and positive regulation of cell population proliferation. Localizes to cell surface; extracellular space; and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; reproductive system; and urethra. Orthologous to human WNT3A (Wnt family member 3A); PARTICIPATES IN Wnt signaling, canonical pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: vestigial tail; vt; wingless-related MMTV integration site 3A; Wnt-; Wnt-3a
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (TAS)
anterior/posterior pattern specification  (IDA)
axis elongation involved in somitogenesis  (IGI)
axon guidance  (IDA)
axonogenesis  (IDA,IGI)
BMP signaling pathway  (ISO)
calcium ion transmembrane transport via low voltage-gated calcium channel  (IDA)
canonical Wnt signaling pathway  (IBA,IDA,IGI,IMP,ISO)
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment  (ISO)
cardiac muscle cell fate commitment  (IGI)
cell fate commitment  (IBA)
cell population proliferation  (ISO)
cell proliferation in forebrain  (IDA)
cell proliferation in midbrain  (IDA)
cell-cell signaling  (TAS)
cellular protein localization  (IDA)
COP9 signalosome assembly  (IDA)
determination of left/right symmetry  (IMP)
dopaminergic neuron differentiation  (TAS)
dorsal/ventral neural tube patterning  (IMP)
extracellular matrix organization  (IDA)
heart looping  (IMP)
hemopoiesis  (IDA)
hippocampus development  (IMP)
in utero embryonic development  (IMP)
inner ear morphogenesis  (IGI)
mammary gland development  (IDA)
mesoderm development  (IMP)
midbrain development  (IDA)
modulation of chemical synaptic transmission  (EXP,IDA,IMP)
multicellular organism development  (IEA)
negative regulation of axon extension involved in axon guidance  (IDA)
negative regulation of dopaminergic neuron differentiation  (IDA)
negative regulation of fat cell differentiation  (IDA,IGI)
negative regulation of heart induction by canonical Wnt signaling pathway  (ISO)
negative regulation of neurogenesis  (IDA)
negative regulation of neuron death  (IGI)
negative regulation of neuron projection development  (IDA)
neurogenesis  (IDA)
neuron differentiation  (IBA)
osteoblast differentiation  (IGI)
paraxial mesodermal cell fate commitment  (IMP)
platelet activation  (IDA)
platelet aggregation  (IDA)
positive regulation of B cell proliferation  (IDA)
positive regulation of canonical Wnt signaling pathway  (IDA,ISO)
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation  (IDA)
positive regulation of cardiac muscle cell differentiation  (ISO)
positive regulation of cell population proliferation  (IDA)
positive regulation of cell-cell adhesion mediated by cadherin  (IDA)
positive regulation of collateral sprouting in absence of injury  (IDA)
positive regulation of core promoter binding  (IMP)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
positive regulation of cytokine production  (IDA)
positive regulation of dermatome development  (ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of gene expression  (ISO)
positive regulation of hepatocyte proliferation  (IDA)
positive regulation of mesodermal cell fate specification  (ISO)
positive regulation of neural precursor cell proliferation  (IDA)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein binding  (ISO)
positive regulation of protein kinase activity  (IDA)
positive regulation of protein localization to plasma membrane  (IDA)
positive regulation of protein phosphorylation  (IDA,ISO)
positive regulation of protein tyrosine kinase activity  (IGI)
positive regulation of receptor internalization  (ISO)
positive regulation of skeletal muscle tissue development  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,ISO,NAS)
positive regulation of transcription, DNA-templated  (IDA)
post-anal tail morphogenesis  (IMP)
postsynapse to nucleus signaling pathway  (EXP,IDA)
regulation of axonogenesis  (IGI)
regulation of cell differentiation  (IDA)
regulation of microtubule cytoskeleton organization  (IGI)
regulation of presynapse assembly  (ISO)
regulation of RNA biosynthetic process  (IDA)
regulation of synapse organization  (ISO)
secondary palate development  (ISO)
signal transduction  (TAS)
skeletal muscle cell differentiation  (IGI)
somatic stem cell division  (IDA)
somitogenesis  (IMP)
spinal cord association neuron differentiation  (IDA,IGI)
Wnt signaling pathway  (IGI)
Wnt signaling pathway involved in forebrain neuroblast division  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone ossification  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal cortical marginal zone morphology  (IAGP)
abnormal dermomyotome development  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal forebrain development  (IAGP)
abnormal gastrulation  (IAGP)
abnormal heart morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal melanoblast morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal metencephalon morphology  (IAGP)
abnormal midbrain development  (IAGP)
abnormal myotome development  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural tube morphology  (IEA)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal somite development  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal tail bud morphology  (IEA)
abnormal tail morphology  (IEA)
abnormal tailgut morphology  (IEA)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thyroid cartilage morphology  (IAGP)
abnormal urination  (IAGP)
abnormal vertebrae morphology  (IAGP)
absent Cajal-Retzius cell  (IAGP)
absent choroid plexus  (IAGP)
absent hindlimb  (IAGP)
absent hyoid bone  (IAGP)
absent sacral vertebrae  (IAGP)
absent stapes  (IAGP)
absent tail  (IAGP)
absent tail bud  (IAGP)
caudal body truncation  (IAGP)
cervical vertebral transformation  (IAGP)
cleft palate  (IAGP)
decreased body length  (IAGP)
decreased Cajal-Retzius cell number  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased embryo size  (IAGP)
decreased lumbar vertebrae number  (IAGP)
decreased thoracic vertebrae number  (IAGP)
decreased ventral ectodermal ridge size  (IEA)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
failure of somite differentiation  (IAGP)
hindlimb paralysis  (IAGP)
incomplete somite formation  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lumbar vertebral transformation  (IAGP)
postnatal lethality  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
sacral vertebral transformation  (IAGP)
short mandible  (IAGP)
sirenomelia  (IAGP)
small alisphenoid bone  (IAGP)
small basisphenoid bone  (IAGP)
small dorsal root ganglion  (IAGP)
small otic capsule  (IAGP)
small presphenoid bone  (IAGP)
small temporal bone squamous part  (IAGP)
spina bifida  (IAGP)
thoracic vertebral transformation  (IAGP)
truncated notochord  (IAGP)
ventricular septal defect  (IAGP)
vestigial tail  (IAGP)
References

Additional References at PubMed
PMID:1018005   PMID:1534034   PMID:2001840   PMID:3388045   PMID:3429842   PMID:4819561   PMID:6313869   PMID:7139332   PMID:7482350   PMID:7556445   PMID:7660319   PMID:7698769  
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PMID:18809738   PMID:18832654   PMID:18842901   PMID:18851995   PMID:18927151   PMID:18929644   PMID:18946023   PMID:18951693   PMID:18983965   PMID:18983966   PMID:18991257   PMID:19001373  
PMID:19020026   PMID:19075000   PMID:19129494   PMID:19139264   PMID:19144919   PMID:19168680   PMID:19185060   PMID:19268448   PMID:19282366   PMID:19285468   PMID:19298762   PMID:19324011  
PMID:19353691   PMID:19369396   PMID:19448146   PMID:19497282   PMID:19515997   PMID:19527706   PMID:19539783   PMID:19542358   PMID:19556343   PMID:19562671   PMID:19563800   PMID:19564486  
PMID:19591802   PMID:19690384   PMID:19699733   PMID:19701191   PMID:19705445   PMID:19732765   PMID:19734891   PMID:19755491   PMID:19805388   PMID:19806668   PMID:19819227   PMID:19820705  
PMID:19841259   PMID:19846726   PMID:19850029   PMID:19853565   PMID:19875668   PMID:19887680   PMID:19890917   PMID:19896444   PMID:19901330   PMID:19906845   PMID:19906857   PMID:19910923  
PMID:19920076   PMID:19924825   PMID:19929441   PMID:19961844   PMID:20093360   PMID:20093472   PMID:20171206   PMID:20179324   PMID:20194509   PMID:20211162   PMID:20371816   PMID:20399290  
PMID:20436479   PMID:20445055   PMID:20569694   PMID:20589426   PMID:20610746   PMID:20634317   PMID:20667980   PMID:20668165   PMID:20668538   PMID:20685998   PMID:20713502   PMID:20722074  
PMID:20801112   PMID:20802155   PMID:20804755   PMID:20808958   PMID:20810787   PMID:20810909   PMID:20816794   PMID:20826466   PMID:20940229   PMID:20940260   PMID:21041481   PMID:21061158  
PMID:21078818   PMID:21123170   PMID:21138436   PMID:21172336   PMID:21185282   PMID:21189423   PMID:21244856   PMID:21246653   PMID:21267068   PMID:21289176   PMID:21308863   PMID:21319221  
PMID:21331042   PMID:21368052   PMID:21368122   PMID:21411632   PMID:21422228   PMID:21467208   PMID:21486944   PMID:21539518   PMID:21539826   PMID:21554246   PMID:21559415   PMID:21599637  
PMID:21606194   PMID:21611174   PMID:21623369   PMID:21652632   PMID:21677750   PMID:21685894   PMID:21731673   PMID:21743455   PMID:21750544   PMID:21752936   PMID:21768372   PMID:21799763  
PMID:21841791   PMID:21873635   PMID:21896628   PMID:21925158   PMID:21936019   PMID:21968811   PMID:21975427   PMID:22003828   PMID:22024319   PMID:22083958   PMID:22105568   PMID:22150562  
PMID:22158103   PMID:22166339   PMID:22213482   PMID:22234613   PMID:22238613   PMID:22274864   PMID:22303445   PMID:22326917   PMID:22357953   PMID:22421355   PMID:22423111   PMID:22465131  
PMID:22479388   PMID:22484060   PMID:22546692   PMID:22575959   PMID:22589174   PMID:22627288   PMID:22665494   PMID:22675207   PMID:22689267   PMID:22689450   PMID:22710324   PMID:22723415  
PMID:22726442   PMID:22761943   PMID:22819676   PMID:22889265   PMID:22899650   PMID:22923088   PMID:22940627   PMID:22954964   PMID:22956684   PMID:22960234   PMID:22983114   PMID:22986341  
PMID:22991247   PMID:23019370   PMID:23032104   PMID:23056351   PMID:23095888   PMID:23154940   PMID:23190887   PMID:23239518   PMID:23296977   PMID:23395374   PMID:23400998   PMID:23436999  
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PMID:27144312   PMID:27150625   PMID:27217206   PMID:27341073   PMID:27369076   PMID:27411055   PMID:27450807   PMID:27453501   PMID:27510977   PMID:27544306   PMID:27557659   PMID:27633082  
PMID:27649680   PMID:27770010   PMID:27871306   PMID:27894818   PMID:28009284   PMID:28009287   PMID:28031177   PMID:28069946   PMID:28087565   PMID:28087631   PMID:28093227   PMID:28188179  
PMID:28219675   PMID:28320874   PMID:28331224   PMID:28637318   PMID:28710407   PMID:28729440   PMID:28808228   PMID:28813421   PMID:28834739   PMID:29176883   PMID:29184203   PMID:29199847  
PMID:29229772   PMID:29394901   PMID:29420689   PMID:29636380   PMID:29740905   PMID:29806907   PMID:29891676   PMID:29937280   PMID:30061166   PMID:30084950   PMID:30139740   PMID:30189017  
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PMID:30692221   PMID:30879996   PMID:30894540   PMID:30940800   PMID:30953627   PMID:31119171   PMID:31147591   PMID:31167144   PMID:31222549   PMID:31235634   PMID:31257105   PMID:31308417  
PMID:31647919   PMID:31727925   PMID:31729356   PMID:31884387   PMID:31891351   PMID:32012381   PMID:32098078   PMID:32156757   PMID:32253237   PMID:32597756   PMID:32616667   PMID:32755451  
PMID:32994168  


Genomics

Comparative Map Data
Wnt3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
WNT3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1228,006,998 - 228,061,271 (+)EnsemblGRCh38hg38GRCh38
GRCh381228,006,998 - 228,067,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,194,723 - 228,248,972 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,261,375 - 226,315,584 (+)NCBINCBI36hg18NCBI36
Build 341224,501,486 - 224,555,696NCBI
Celera1201,384,988 - 201,439,196 (+)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1198,726,487 - 198,764,776 (+)NCBIHuRef
CHM1_11229,467,104 - 229,521,343 (+)NCBICHM1_1
Wnt3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01045,598,898 - 45,643,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,598,912 - 45,638,035 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01045,354,369 - 45,398,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,553,682 - 45,594,983 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,567,304 - 45,609,958 (-)NCBI
Celera1043,297,443 - 43,336,315 (-)NCBICelera
Cytogenetic Map10q22NCBI
Wnt3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955581350,889 - 382,541 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955581351,375 - 382,541 (-)NCBIChiLan1.0ChiLan1.0
WNT3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11208,628,706 - 208,674,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1208,628,706 - 208,674,469 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01203,409,294 - 203,463,214 (+)NCBIMhudiblu_PPA_v0panPan3
WNT3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl14863,424 - 896,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.114864,393 - 899,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Wnt3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936864150,742 - 179,205 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,154,086 - 51,202,176 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,153,978 - 51,203,678 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,908,485 - 53,958,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT3A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,664,316 - 1,675,006 (-)NCBI
Wnt3a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937816,752 - 845,866 (+)NCBI

Position Markers
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,104 - 59,249,647UniSTSGRCm38
MGSCv371159,062,606 - 59,063,149UniSTSGRCm37
Celera1164,014,105 - 64,014,648UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
PMC26484P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,229 - 59,249,541UniSTSGRCm38
MGSCv371159,062,731 - 59,063,043UniSTSGRCm37
Celera1164,014,230 - 64,014,542UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,988UniSTSGRCm38
MGSCv371159,061,652 - 59,062,490UniSTSGRCm37
Celera1164,013,151 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,657 - 59,248,975UniSTSGRCm38
MGSCv371159,062,159 - 59,062,477UniSTSGRCm37
Celera1164,013,658 - 64,013,976UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,554 - 59,249,087UniSTSGRCm38
MGSCv371159,062,056 - 59,062,589UniSTSGRCm37
Celera1164,013,555 - 64,014,088UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,376UniSTSGRCm38
MGSCv371159,061,652 - 59,061,878UniSTSGRCm37
Celera1164,013,151 - 64,013,377UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,827 - 59,248,988UniSTSGRCm38
MGSCv371159,062,329 - 59,062,490UniSTSGRCm37
Celera1164,013,828 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir16-2mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir16-1mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pOncomiRDBexternal_infoNANA21106054

Predicted Target Of
Summary Value
Count of predictions:686
Count of miRNA genes:416
Interacting mature miRNAs:492
Transcripts:ENSMUST00000010044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000010044   ⟹   ENSMUSP00000010044
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)Ensembl
RefSeq Acc Id: NM_009522   ⟹   NP_033548
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391159,138,862 - 59,181,577 (-)NCBI
GRCm381159,248,036 - 59,290,751 (-)ENTREZGENE
MGSCv371159,061,538 - 59,104,253 (-)RGD
Celera1164,013,041 - 64,056,135 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033548 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA40173 (Get FASTA)   NCBI Sequence Viewer  
  CAI38662 (Get FASTA)   NCBI Sequence Viewer  
  EDL07662 (Get FASTA)   NCBI Sequence Viewer  
  P27467 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033548   ⟸   NM_009522
- Peptide Label: precursor
- UniProtKB: P27467 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000010044   ⟸   ENSMUST00000010044

Promoters
RGD ID:8674820
Promoter ID:EPDNEW_M15434
Type:initiation region
Name:Wnt3a_1
Description:Mus musculus wingless-type MMTV integration site family, member3A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381159,290,753 - 59,290,813EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98956 AgrOrtholog
Ensembl Genes ENSMUSG00000009900 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.2460.20 UniProtKB/Swiss-Prot
InterPro Wnt UniProtKB/Swiss-Prot
  Wnt3 UniProtKB/Swiss-Prot
  Wnt_C UniProtKB/Swiss-Prot
  Wnt_CS UniProtKB/Swiss-Prot
KEGG Report mmu:22416 UniProtKB/Swiss-Prot
MGD MGI:98956 ENTREZGENE
NCBI Gene 22416 ENTREZGENE
PANTHER PTHR12027 UniProtKB/Swiss-Prot
Pfam wnt UniProtKB/Swiss-Prot
PhenoGen Wnt3a PhenoGen
PRINTS WNT3PROTEIN UniProtKB/Swiss-Prot
  WNTPROTEIN UniProtKB/Swiss-Prot
PROSITE WNT1 UniProtKB/Swiss-Prot
SMART WNT1 UniProtKB/Swiss-Prot
UniGene Mm.1367 ENTREZGENE
UniProt P27467 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 Wnt3a  wingless-type MMTV integration site family, member 3A    wingless-related MMTV integration site 3A  Symbol and/or name change 5135510 APPROVED