Wnt3a (wingless-type MMTV integration site family, member 3A) - Rat Genome Database
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Gene: Wnt3a (wingless-type MMTV integration site family, member 3A) Mus musculus
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Symbol: Wnt3a
Name: wingless-type MMTV integration site family, member 3A
RGD ID: 1317607
MGI Page MGI
Description: Exhibits frizzled binding activity; molecular function regulator; and protein domain specific binding activity. Involved in several processes, including animal organ development; nervous system development; and positive regulation of cell population proliferation. Localizes to cell surface; extracellular space; and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; reproductive system; and urethra. Orthologous to human WNT3A (Wnt family member 3A); PARTICIPATES IN Wnt signaling, canonical pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: vestigial tail; vt; wingless-related MMTV integration site 3A; Wnt-; Wnt-3a
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (TAS)
anterior/posterior pattern specification  (IDA)
axis elongation involved in somitogenesis  (IGI)
axon guidance  (IDA)
axonogenesis  (IDA,IGI)
BMP signaling pathway  (ISO)
calcium ion transmembrane transport via low voltage-gated calcium channel  (IDA)
canonical Wnt signaling pathway  (IBA,IDA,IGI,IMP,ISO)
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment  (ISO)
cardiac muscle cell fate commitment  (IGI)
cell fate commitment  (IBA)
cell population proliferation  (ISO)
cell proliferation in forebrain  (IDA)
cell proliferation in midbrain  (IDA)
cell-cell signaling  (TAS)
cellular protein localization  (IDA)
COP9 signalosome assembly  (IDA)
determination of left/right symmetry  (IMP)
dopaminergic neuron differentiation  (TAS)
dorsal/ventral neural tube patterning  (IMP)
extracellular matrix organization  (IDA)
heart looping  (IMP)
hemopoiesis  (IDA)
hippocampus development  (IMP)
in utero embryonic development  (IMP)
inner ear morphogenesis  (IGI)
mammary gland development  (IDA)
mesoderm development  (IMP)
midbrain development  (IDA)
modulation of chemical synaptic transmission  (EXP,IDA,IMP)
multicellular organism development  (IEA)
negative regulation of axon extension involved in axon guidance  (IDA)
negative regulation of dopaminergic neuron differentiation  (IDA)
negative regulation of fat cell differentiation  (IDA,IGI)
negative regulation of heart induction by canonical Wnt signaling pathway  (ISO)
negative regulation of neurogenesis  (IDA)
negative regulation of neuron death  (IGI)
negative regulation of neuron projection development  (IDA)
neurogenesis  (IDA)
neuron differentiation  (IBA)
osteoblast differentiation  (IGI)
paraxial mesodermal cell fate commitment  (IMP)
platelet activation  (IDA)
platelet aggregation  (IDA)
positive regulation of B cell proliferation  (IDA)
positive regulation of canonical Wnt signaling pathway  (IDA,ISO)
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation  (IDA)
positive regulation of cardiac muscle cell differentiation  (ISO)
positive regulation of cell population proliferation  (IDA)
positive regulation of cell-cell adhesion mediated by cadherin  (IDA)
positive regulation of collateral sprouting in absence of injury  (IDA)
positive regulation of core promoter binding  (IMP)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
positive regulation of cytokine production  (IDA)
positive regulation of dermatome development  (ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of gene expression  (ISO)
positive regulation of hepatocyte proliferation  (IDA)
positive regulation of mesodermal cell fate specification  (ISO)
positive regulation of neural precursor cell proliferation  (IDA)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein binding  (ISO)
positive regulation of protein kinase activity  (IDA)
positive regulation of protein localization to plasma membrane  (IDA)
positive regulation of protein phosphorylation  (IDA,ISO)
positive regulation of protein tyrosine kinase activity  (IGI)
positive regulation of receptor internalization  (ISO)
positive regulation of skeletal muscle tissue development  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,ISO,NAS)
positive regulation of transcription, DNA-templated  (IDA)
post-anal tail morphogenesis  (IMP)
postsynapse to nucleus signaling pathway  (EXP,IDA)
regulation of axonogenesis  (IGI)
regulation of cell differentiation  (IDA)
regulation of microtubule cytoskeleton organization  (IGI)
regulation of presynapse assembly  (ISO)
regulation of RNA biosynthetic process  (IDA)
regulation of synapse organization  (ISO)
secondary palate development  (ISO)
signal transduction  (TAS)
skeletal muscle cell differentiation  (IGI)
somatic stem cell division  (IDA)
somitogenesis  (IMP)
spinal cord association neuron differentiation  (IDA,IGI)
Wnt signaling pathway  (IGI)
Wnt signaling pathway involved in forebrain neuroblast division  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone ossification  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal cortical marginal zone morphology  (IAGP)
abnormal dermomyotome development  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal forebrain development  (IAGP)
abnormal gastrulation  (IAGP)
abnormal heart morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal melanoblast morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal metencephalon morphology  (IAGP)
abnormal midbrain development  (IAGP)
abnormal myotome development  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural tube morphology  (IEA)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal somite development  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal tail bud morphology  (IEA)
abnormal tail morphology  (IEA)
abnormal tailgut morphology  (IEA)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thyroid cartilage morphology  (IAGP)
abnormal urination  (IAGP)
abnormal vertebrae morphology  (IAGP)
absent Cajal-Retzius cell  (IAGP)
absent choroid plexus  (IAGP)
absent hindlimb  (IAGP)
absent hyoid bone  (IAGP)
absent sacral vertebrae  (IAGP)
absent stapes  (IAGP)
absent tail  (IAGP)
absent tail bud  (IAGP)
caudal body truncation  (IAGP)
cervical vertebral transformation  (IAGP)
cleft palate  (IAGP)
decreased body length  (IAGP)
decreased Cajal-Retzius cell number  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased embryo size  (IAGP)
decreased lumbar vertebrae number  (IAGP)
decreased thoracic vertebrae number  (IAGP)
decreased ventral ectodermal ridge size  (IEA)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
failure of somite differentiation  (IAGP)
hindlimb paralysis  (IAGP)
incomplete somite formation  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lumbar vertebral transformation  (IAGP)
postnatal lethality  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
sacral vertebral transformation  (IAGP)
short mandible  (IAGP)
sirenomelia  (IAGP)
small alisphenoid bone  (IAGP)
small basisphenoid bone  (IAGP)
small dorsal root ganglion  (IAGP)
small otic capsule  (IAGP)
small presphenoid bone  (IAGP)
small temporal bone squamous part  (IAGP)
spina bifida  (IAGP)
thoracic vertebral transformation  (IAGP)
truncated notochord  (IAGP)
ventricular septal defect  (IAGP)
vestigial tail  (IAGP)
References

Additional References at PubMed
PMID:1018005   PMID:1534034   PMID:2001840   PMID:3388045   PMID:3429842   PMID:4819561   PMID:6313869   PMID:7139332   PMID:7482350   PMID:7556445   PMID:7660319   PMID:7698769  
PMID:7720556   PMID:7915533   PMID:8050356   PMID:8111977   PMID:8167409   PMID:8275860   PMID:8299937   PMID:8565855   PMID:8575294   PMID:8595882   PMID:8662242   PMID:8756299  
PMID:8887323   PMID:8951061   PMID:9006071   PMID:9070329   PMID:9070927   PMID:9126297   PMID:9160667   PMID:9334279   PMID:9353119   PMID:9356179   PMID:9490412   PMID:9529344  
PMID:9584130   PMID:9799734   PMID:9811581   PMID:9882496   PMID:9889131   PMID:9891778   PMID:10049592   PMID:10090727   PMID:10409711   PMID:10473117   PMID:10498273   PMID:10516314  
PMID:10557084   PMID:10585256   PMID:10585775   PMID:10589677   PMID:10617567   PMID:10625551   PMID:10631167   PMID:10642791   PMID:10677508   PMID:10729342   PMID:10817753   PMID:10866835  
PMID:10893270   PMID:10933391   PMID:10946068   PMID:11029008   PMID:11134352   PMID:11157778   PMID:11165475   PMID:11262239   PMID:11335109   PMID:11429295   PMID:11447280   PMID:11509733  
PMID:11520664   PMID:11703922   PMID:11739261   PMID:11784033   PMID:11836627   PMID:11856745   PMID:11877374   PMID:11914369   PMID:12070081   PMID:12077113   PMID:12118260   PMID:12121999  
PMID:12196475   PMID:12351199   PMID:12361972   PMID:12421714   PMID:12466851   PMID:12490556   PMID:12533510   PMID:12588859   PMID:12610652   PMID:12636920   PMID:12642494   PMID:12717450  
PMID:12717451   PMID:12719544   PMID:12799076   PMID:12815618   PMID:12843296   PMID:12874124   PMID:12878679   PMID:12897152   PMID:12921747   PMID:12925582   PMID:12952940   PMID:13002376  
PMID:14557550   PMID:14681479   PMID:14706629   PMID:14722104   PMID:14723853   PMID:14732490   PMID:14832454   PMID:15044261   PMID:15136723   PMID:15143170   PMID:15143193   PMID:15147765  
PMID:15148409   PMID:15226823   PMID:15265686   PMID:15270777   PMID:15342465   PMID:15454084   PMID:15469968   PMID:15469980   PMID:15509575   PMID:15509764   PMID:15511637   PMID:15537664  
PMID:15545262   PMID:15545629   PMID:15579909   PMID:15615777   PMID:15650056   PMID:15665828   PMID:15708565   PMID:15778975   PMID:15789444   PMID:15791206   PMID:15796911   PMID:15843411  
PMID:15849360   PMID:15857914   PMID:15858069   PMID:15880404   PMID:15917450   PMID:15950605   PMID:15955531   PMID:15961523   PMID:15994435   PMID:16099458   PMID:16109169   PMID:16115200  
PMID:16127714   PMID:16150699   PMID:16243425   PMID:16251184   PMID:16291790   PMID:16303557   PMID:16309666   PMID:16368545   PMID:16378759   PMID:16393701   PMID:16397896   PMID:16410414  
PMID:16467359   PMID:16501258   PMID:16516838   PMID:16524929   PMID:16543246   PMID:16565323   PMID:16581771   PMID:16583142   PMID:16602821   PMID:16602827   PMID:16621789   PMID:16678101  
PMID:16766714   PMID:16799642   PMID:16801545   PMID:16806848   PMID:16818446   PMID:16824228   PMID:16855091   PMID:16893423   PMID:16914735   PMID:16971467   PMID:17027228   PMID:17055474  
PMID:17064353   PMID:17095659   PMID:17117439   PMID:17170140   PMID:17199045   PMID:17244647   PMID:17251350   PMID:17280871   PMID:17335794   PMID:17350462   PMID:17360443   PMID:17360769  
PMID:17372190   PMID:17397399   PMID:17428233   PMID:17428999   PMID:17462603   PMID:17468181   PMID:17490632   PMID:17507393   PMID:17507568   PMID:17510396   PMID:17522258   PMID:17569865  
PMID:17595165   PMID:17606995   PMID:17609021   PMID:17611225   PMID:17644613   PMID:17668009   PMID:17698587   PMID:17717053   PMID:17765217   PMID:17804636   PMID:17855383   PMID:17855431  
PMID:17881570   PMID:17888405   PMID:17916803   PMID:17928452   PMID:17932314   PMID:17937396   PMID:17943183   PMID:17953485   PMID:17959802   PMID:17982705   PMID:17983805   PMID:17994217  
PMID:18045842   PMID:18045882   PMID:18057099   PMID:18094027   PMID:18155657   PMID:18192238   PMID:18202285   PMID:18212053   PMID:18227807   PMID:18242177   PMID:18257070   PMID:18287559  
PMID:18351675   PMID:18364260   PMID:18448089   PMID:18452624   PMID:18505824   PMID:18528331   PMID:18541538   PMID:18555765   PMID:18575602   PMID:18579678   PMID:18606138   PMID:18635608  
PMID:18667431   PMID:18676816   PMID:18694563   PMID:18697220   PMID:18697834   PMID:18698373   PMID:18716223   PMID:18724388   PMID:18768850   PMID:18794329   PMID:18799693   PMID:18800919  
PMID:18809738   PMID:18832654   PMID:18842901   PMID:18851995   PMID:18927151   PMID:18929644   PMID:18946023   PMID:18951693   PMID:18983965   PMID:18983966   PMID:18991257   PMID:19001373  
PMID:19020026   PMID:19075000   PMID:19129494   PMID:19139264   PMID:19144919   PMID:19168680   PMID:19185060   PMID:19268448   PMID:19282366   PMID:19285468   PMID:19298762   PMID:19324011  
PMID:19353691   PMID:19369396   PMID:19448146   PMID:19497282   PMID:19515997   PMID:19527706   PMID:19539783   PMID:19542358   PMID:19556343   PMID:19562671   PMID:19563800   PMID:19564486  
PMID:19591802   PMID:19690384   PMID:19699733   PMID:19701191   PMID:19705445   PMID:19732765   PMID:19734891   PMID:19755491   PMID:19805388   PMID:19806668   PMID:19819227   PMID:19820705  
PMID:19841259   PMID:19846726   PMID:19850029   PMID:19853565   PMID:19875668   PMID:19887680   PMID:19890917   PMID:19896444   PMID:19901330   PMID:19906845   PMID:19906857   PMID:19910923  
PMID:19920076   PMID:19924825   PMID:19929441   PMID:19961844   PMID:20093360   PMID:20093472   PMID:20171206   PMID:20179324   PMID:20194509   PMID:20211162   PMID:20371816   PMID:20399290  
PMID:20436479   PMID:20445055   PMID:20569694   PMID:20589426   PMID:20610746   PMID:20634317   PMID:20667980   PMID:20668165   PMID:20668538   PMID:20685998   PMID:20713502   PMID:20722074  
PMID:20801112   PMID:20802155   PMID:20804755   PMID:20808958   PMID:20810787   PMID:20810909   PMID:20816794   PMID:20826466   PMID:20940229   PMID:20940260   PMID:21041481   PMID:21061158  
PMID:21078818   PMID:21123170   PMID:21138436   PMID:21172336   PMID:21185282   PMID:21189423   PMID:21244856   PMID:21246653   PMID:21267068   PMID:21289176   PMID:21308863   PMID:21319221  
PMID:21331042   PMID:21368052   PMID:21368122   PMID:21411632   PMID:21422228   PMID:21467208   PMID:21486944   PMID:21539518   PMID:21539826   PMID:21554246   PMID:21559415   PMID:21599637  
PMID:21606194   PMID:21611174   PMID:21623369   PMID:21652632   PMID:21677750   PMID:21685894   PMID:21731673   PMID:21743455   PMID:21750544   PMID:21752936   PMID:21768372   PMID:21799763  
PMID:21841791   PMID:21873635   PMID:21896628   PMID:21925158   PMID:21936019   PMID:21968811   PMID:21975427   PMID:22003828   PMID:22024319   PMID:22083958   PMID:22105568   PMID:22150562  
PMID:22158103   PMID:22166339   PMID:22213482   PMID:22234613   PMID:22238613   PMID:22274864   PMID:22303445   PMID:22326917   PMID:22357953   PMID:22421355   PMID:22423111   PMID:22465131  
PMID:22479388   PMID:22484060   PMID:22546692   PMID:22575959   PMID:22589174   PMID:22627288   PMID:22665494   PMID:22675207   PMID:22689267   PMID:22689450   PMID:22710324   PMID:22723415  
PMID:22726442   PMID:22761943   PMID:22819676   PMID:22889265   PMID:22899650   PMID:22923088   PMID:22940627   PMID:22954964   PMID:22956684   PMID:22960234   PMID:22983114   PMID:22986341  
PMID:22991247   PMID:23019370   PMID:23032104   PMID:23056351   PMID:23095888   PMID:23154940   PMID:23190887   PMID:23239518   PMID:23296977   PMID:23395374   PMID:23400998   PMID:23436999  
PMID:23447624   PMID:23454273   PMID:23469192   PMID:23520113   PMID:23534675   PMID:23613470   PMID:23623748   PMID:23649620   PMID:23671110   PMID:23677472   PMID:23740243   PMID:23763947  
PMID:23791946   PMID:23827310   PMID:23863479   PMID:23884445   PMID:23931996   PMID:24006258   PMID:24080158   PMID:24101523   PMID:24114209   PMID:24151333   PMID:24246780   PMID:24318810  
PMID:24318811   PMID:24340027   PMID:24371086   PMID:24394376   PMID:24403153   PMID:24444608   PMID:24475213   PMID:24548083   PMID:24569166   PMID:24586192   PMID:24643512   PMID:24798332  
PMID:24801048   PMID:24815018   PMID:24832538   PMID:24841207   PMID:24841652   PMID:24859004   PMID:24867947   PMID:24885675   PMID:24922070   PMID:24952961   PMID:24995796   PMID:25002511  
PMID:25038457   PMID:25053429   PMID:25071457   PMID:25084050   PMID:25147340   PMID:25152336   PMID:25182747   PMID:25253849   PMID:25336178   PMID:25371364   PMID:25691658   PMID:25753732  
PMID:25809880   PMID:25813538   PMID:25854560   PMID:25922526   PMID:25926459   PMID:26006230   PMID:26038536   PMID:26085341   PMID:26189772   PMID:26266404   PMID:26371318   PMID:26377473  
PMID:26387718   PMID:26414873   PMID:26443994   PMID:26671461   PMID:26740630   PMID:26744331   PMID:26846714   PMID:26902720   PMID:26956881   PMID:27048518   PMID:27127101   PMID:27129247  
PMID:27144312   PMID:27150625   PMID:27217206   PMID:27341073   PMID:27369076   PMID:27411055   PMID:27450807   PMID:27453501   PMID:27510977   PMID:27544306   PMID:27557659   PMID:27633082  
PMID:27649680   PMID:27770010   PMID:27871306   PMID:27894818   PMID:28009284   PMID:28009287   PMID:28031177   PMID:28069946   PMID:28087565   PMID:28087631   PMID:28093227   PMID:28188179  
PMID:28219675   PMID:28320874   PMID:28331224   PMID:28637318   PMID:28710407   PMID:28729440   PMID:28808228   PMID:28813421   PMID:28834739   PMID:29176883   PMID:29184203   PMID:29199847  
PMID:29229772   PMID:29394901   PMID:29420689   PMID:29636380   PMID:29740905   PMID:29806907   PMID:29891676   PMID:29937280   PMID:30061166   PMID:30084950   PMID:30139740   PMID:30189017  
PMID:30220568   PMID:30228991   PMID:30256721   PMID:30347193   PMID:30459452   PMID:30485816   PMID:30548789   PMID:30550847   PMID:30559277   PMID:30622240   PMID:30651295   PMID:30664649  
PMID:30692221   PMID:30879996   PMID:30894540   PMID:30940800   PMID:30953627   PMID:31119171   PMID:31147591   PMID:31167144   PMID:31222549   PMID:31235634   PMID:31257105   PMID:31308417  
PMID:31647919   PMID:31727925   PMID:31729356   PMID:31884387   PMID:31891351   PMID:32012381   PMID:32098078   PMID:32156757   PMID:32253237   PMID:32597756   PMID:32616667   PMID:32755451  
PMID:32994168  


Genomics

Comparative Map Data
Wnt3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,138,862 - 59,181,577 (-)NCBIGRCm39mm39
GRCm381159,248,036 - 59,290,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,061,538 - 59,104,253 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,064,231 - 59,106,946 (-)NCBImm8
Celera1164,013,041 - 64,056,135 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.17NCBI
WNT3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1228,006,998 - 228,061,271 (+)EnsemblGRCh38hg38GRCh38
GRCh381228,006,998 - 228,067,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,194,723 - 228,248,972 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,261,375 - 226,315,584 (+)NCBINCBI36hg18NCBI36
Build 341224,501,486 - 224,555,696NCBI
Celera1201,384,988 - 201,439,196 (+)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1198,726,487 - 198,764,776 (+)NCBIHuRef
CHM1_11229,467,104 - 229,521,343 (+)NCBICHM1_1
Wnt3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01045,598,898 - 45,643,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,598,912 - 45,638,035 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01045,354,369 - 45,398,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,553,682 - 45,594,983 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,567,304 - 45,609,958 (-)NCBI
Celera1043,297,443 - 43,336,315 (-)NCBICelera
Cytogenetic Map10q22NCBI
Wnt3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955581350,889 - 382,541 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955581351,375 - 382,541 (-)NCBIChiLan1.0ChiLan1.0
WNT3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11208,628,706 - 208,674,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1208,628,706 - 208,674,469 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01203,409,294 - 203,463,214 (+)NCBIMhudiblu_PPA_v0panPan3
WNT3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl14863,424 - 896,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.114864,393 - 899,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Wnt3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936864150,742 - 179,205 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,154,086 - 51,202,176 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,153,978 - 51,203,678 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,908,485 - 53,958,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT3A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,664,316 - 1,675,006 (-)NCBI
Wnt3a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937816,752 - 845,866 (+)NCBI

Position Markers
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,104 - 59,249,647UniSTSGRCm38
MGSCv371159,062,606 - 59,063,149UniSTSGRCm37
Celera1164,014,105 - 64,014,648UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
PMC26484P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,249,229 - 59,249,541UniSTSGRCm38
MGSCv371159,062,731 - 59,063,043UniSTSGRCm37
Celera1164,014,230 - 64,014,542UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,988UniSTSGRCm38
MGSCv371159,061,652 - 59,062,490UniSTSGRCm37
Celera1164,013,151 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,657 - 59,248,975UniSTSGRCm38
MGSCv371159,062,159 - 59,062,477UniSTSGRCm37
Celera1164,013,658 - 64,013,976UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,554 - 59,249,087UniSTSGRCm38
MGSCv371159,062,056 - 59,062,589UniSTSGRCm37
Celera1164,013,555 - 64,014,088UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,150 - 59,248,376UniSTSGRCm38
MGSCv371159,061,652 - 59,061,878UniSTSGRCm37
Celera1164,013,151 - 64,013,377UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1132.0UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381159,248,827 - 59,248,988UniSTSGRCm38
MGSCv371159,062,329 - 59,062,490UniSTSGRCm37
Celera1164,013,828 - 64,013,989UniSTS
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Wnt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir16-2mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir16-1mmu-miR-16-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Northern blot//Luciferase rFunctional MTI18931683
Mir15ammu-miR-15a-5pOncomiRDBexternal_infoNANA21106054

Predicted Target Of
Summary Value
Count of predictions:686
Count of miRNA genes:416
Interacting mature miRNAs:492
Transcripts:ENSMUST00000010044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000010044   ⟹   ENSMUSP00000010044
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1159,248,033 - 59,290,752 (-)Ensembl
RefSeq Acc Id: NM_009522   ⟹   NP_033548
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391159,138,862 - 59,181,577 (-)NCBI
GRCm381159,248,036 - 59,290,751 (-)ENTREZGENE
MGSCv371159,061,538 - 59,104,253 (-)RGD
Celera1164,013,041 - 64,056,135 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033548 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA40173 (Get FASTA)   NCBI Sequence Viewer  
  CAI38662 (Get FASTA)   NCBI Sequence Viewer  
  EDL07662 (Get FASTA)   NCBI Sequence Viewer  
  P27467 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033548   ⟸   NM_009522
- Peptide Label: precursor
- UniProtKB: P27467 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000010044   ⟸   ENSMUST00000010044

Promoters
RGD ID:8674820
Promoter ID:EPDNEW_M15434
Type:initiation region
Name:Wnt3a_1
Description:Mus musculus wingless-type MMTV integration site family, member3A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381159,290,753 - 59,290,813EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98956 AgrOrtholog
Ensembl Genes ENSMUSG00000009900 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010044 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.2460.20 UniProtKB/Swiss-Prot
InterPro Wnt UniProtKB/Swiss-Prot
  Wnt3 UniProtKB/Swiss-Prot
  Wnt_C UniProtKB/Swiss-Prot
  Wnt_CS UniProtKB/Swiss-Prot
KEGG Report mmu:22416 UniProtKB/Swiss-Prot
MGD MGI:98956 ENTREZGENE
NCBI Gene 22416 ENTREZGENE
PANTHER PTHR12027 UniProtKB/Swiss-Prot
Pfam wnt UniProtKB/Swiss-Prot
PhenoGen Wnt3a PhenoGen
PRINTS WNT3PROTEIN UniProtKB/Swiss-Prot
  WNTPROTEIN UniProtKB/Swiss-Prot
PROSITE WNT1 UniProtKB/Swiss-Prot
SMART WNT1 UniProtKB/Swiss-Prot
UniGene Mm.1367 ENTREZGENE
UniProt P27467 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 Wnt3a  wingless-type MMTV integration site family, member 3A    wingless-related MMTV integration site 3A  Symbol and/or name change 5135510 APPROVED