Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | affects expression | EXP | | 6480464 | ethylene dichloride affects the expression of NSG2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of NSG2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of NSG2 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NSG2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NSG2 mRNA | CTD | PMID:20159946 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NSG2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NSG2 mRNA | CTD | PMID:17942748 and PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NSG2 mRNA | CTD | PMID:17942748 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of NSG2 gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NSG2 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | increases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of NSG2 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | NSG2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of HMP19 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Tretinoin results in decreased expression of NSG2 mRNA | CTD | PMID:20488242 | benzo[a]pyrene | increases expression | ISO | NSG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NSG2 mRNA | CTD | PMID:17879257 | benzo[a]pyrene | increases methylation | ISO | NSG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HMP19 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of NSG2 mRNA | CTD | PMID:26377693 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NSG2 mRNA | CTD | PMID:30245210 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NSG2 mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NSG2 mRNA | CTD | PMID:36041667 | bisphenol F | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NSG2 mRNA | CTD | PMID:36041667 | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of NSG2 mRNA | CTD | PMID:29038090 | Butylbenzyl phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of NSG2 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of NSG2 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | NSG2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to HMP19 gene] | CTD | PMID:28238834 | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of NSG2 mRNA | CTD | PMID:33711761 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of NSG2 mRNA | CTD | PMID:32715474 | copper atom | multiple interactions | EXP | | 6480464 | MT1 affects the reaction [Copper results in increased expression of NSG2 mRNA] and MT2 affects the reaction [Copper results in increased expression of NSG2 mRNA] | CTD | PMID:16629173 | copper(0) | multiple interactions | EXP | | 6480464 | MT1 affects the reaction [Copper results in increased expression of NSG2 mRNA] and MT2 affects the reaction [Copper results in increased expression of NSG2 mRNA] | CTD | PMID:16629173 | corosolic acid | multiple interactions | EXP | | 6480464 | corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene] | CTD | PMID:32135139 | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of NSG2 mRNA | CTD | PMID:29279043 | dibutyl phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | diethyl phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | diisobutyl phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | diisononyl phthalate | multiple interactions | ISO | Nsg2 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA | CTD | PMID:31199487 | doxorubicin | affects response to substance | ISO | NSG2 (Homo sapiens) | 6480464 | NSG2 mRNA affects the susceptibility to Doxorubicin | CTD | PMID:16044152 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of NSG2 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of NSG2 mRNA | CTD | PMID:22206623 | glyphosate | affects methylation | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Glyphosate affects the methylation of NSG2 gene | CTD | PMID:35440735 | methoxychlor | affects methylation | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of NSG2 gene | CTD | PMID:35440735 | nitrofen | decreases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | nitrofen results in decreased expression of NSG2 mRNA | CTD | PMID:33484710 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NSG2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of NSG2 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of NSG2 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | ISO | Nsg2 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of NSG2 mRNA | CTD | PMID:32680482 | phorbol 13-acetate 12-myristate | multiple interactions | EXP | | 6480464 | corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene] | CTD | PMID:32135139 | phorbol 13-acetate 12-myristate | increases methylation | EXP | | 6480464 | Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene | CTD | PMID:32135139 | pioglitazone | multiple interactions | EXP | | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NSG2 mRNA | CTD | PMID:27935865 | sodium arsenite | affects methylation | ISO | NSG2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of HMP19 gene | CTD | PMID:28589171 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of NSG2 mRNA | CTD | PMID:37682722 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of NSG2 mRNA | CTD | PMID:17555576 | tetraphene | increases expression | EXP | | 6480464 | benz(a)anthracene results in increased expression of NSG2 mRNA | CTD | PMID:26377693 | triclosan | decreases expression | ISO | NSG2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of HMP19 mRNA | CTD | PMID:30510588 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of NSG2 mRNA | CTD | PMID:33045310 | uranium atom | affects expression | ISO | NSG2 (Homo sapiens) | 6480464 | Uranium affects the expression of NSG2 mRNA | CTD | PMID:15672453 | valproic acid | decreases methylation | ISO | NSG2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NSG2 gene | CTD | PMID:29154799 | |