Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Iars2 (isoleucine-tRNA synthetase 2, mitochondrial) Mus musculus
Analyze
Symbol: Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Description: Predicted to have isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation and mitochondrial translation. Localizes to the mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010002H18Rik; C79125; ileRS; isoleucine--tRNA ligase; isoleucine--tRNA ligase, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; MGC63429
Orthologs:
Homo sapiens (human) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1185,284,726 - 185,329,396 (-)Ensembl
GRCm381185,286,642 - 185,329,419 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371187,110,541 - 187,153,280 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,987,450 - 187,030,189 (-)NCBImm8
Celera1192,244,078 - 192,279,032 (-)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Iars2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550834
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.