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Gene: Iars2 (isoleucine-tRNA synthetase 2, mitochondrial) Mus musculus
Symbol: Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Description: Predicted to have isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation and mitochondrial translation. Localizes to the mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010002H18Rik; C79125; ileRS; isoleucine--tRNA ligase; isoleucine--tRNA ligase, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; MGC63429
Homo sapiens (human) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iars2 (isoleucyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1185,284,726 - 185,329,396 (-)Ensembl
GRCm381185,286,642 - 185,329,419 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371187,110,541 - 187,153,280 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,987,450 - 187,030,189 (-)NCBImm8
Celera1192,244,078 - 192,279,032 (-)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Iars2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550834
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.