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Gene: Scn2b (sodium channel, voltage-gated, type II, beta) Mus musculus
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Symbol: Scn2b
Name: sodium channel, voltage-gated, type II, beta
Description: Predicted to have sodium channel regulator activity and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Predicted to be involved in several processes, including cardiac muscle cell action potential; regulation of atrial cardiac muscle cell membrane depolarization; and regulation of heart rate by cardiac conduction. Predicted to localize to the voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Is expressed in several structures, including cranial ganglion and dorsal root ganglion. Orthologous to human SCN2B (sodium voltage-gated channel beta subunit 2); INTERACTS WITH (+)-pilocarpine; ethanol; valproic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810451E09Rik; AI840361; Gm183; MGC116602; sodium channel subunit beta-2; sodium channel, voltage-gated, type II, beta polypeptide
Orthologs:
Homo sapiens (human) : SCN2B (sodium voltage-gated channel beta subunit 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Scn2b (sodium voltage-gated channel beta subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn2b (sodium voltage-gated channel beta subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN2B (sodium voltage-gated channel beta subunit 2)
Canis lupus familiaris (dog) : SCN2B (sodium voltage-gated channel beta subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn2b (sodium voltage-gated channel beta subunit 2)
Sus scrofa (pig) : SCN2B (sodium voltage-gated channel beta subunit 2)
Chlorocebus sabaeus (African green monkey) : SCN2B (sodium voltage-gated channel beta subunit 2)
Heterocephalus glaber (naked mole-rat) : Scn2b (sodium voltage-gated channel beta subunit 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl945,117,782 - 45,130,070 (+)Ensembl
GRCm38945,117,876 - 45,130,070 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37944,925,959 - 44,938,153 (+)NCBIGRCm37mm9NCBIm37
MGSCv36944,868,876 - 44,881,065 (+)NCBImm8
Celera942,393,438 - 42,405,653 (+)NCBICelera
Cytogenetic Map9 A5.2NCBI
cM Map924.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Scn2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11266
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.