(+)-alpha-tocopherol multiple interactions ISO RGD:1606566 6480464 alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1606566 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of BACE1 mRNA CTD PMID:22079256 (25R)-cholest-5-ene-3beta,26-diol increases expression ISO RGD:1606566 6480464 27-hydroxycholesterol results in increased expression of BACE1 protein CTD PMID:19126211 (S)-naringenin decreases activity ISO RGD:1606566 6480464 naringenin results in decreased activity of BACE1 protein CTD PMID:31194956 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of BACE1 mRNA CTD PMID:26682919 17alpha-ethynylestradiol increases expression ISO RGD:2191 6480464 Ethinyl Estradiol results in increased expression of BACE1 mRNA CTD PMID:29097150 2,2,2-tetramine multiple interactions ISO RGD:1606566 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]], Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein] CTD PMID:23541064 2,2,2-tetramine decreases expression ISO RGD:1606566 6480464 Trientine results in decreased expression of BACE1 protein CTD PMID:23541064 2,2,2-tetramine decreases expression EXP 6480464 Trientine results in decreased expression of BACE1 protein CTD PMID:23541064 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of BACE1 mRNA CTD PMID:21570461 26-hydroxycholesterol increases expression ISO RGD:1606566 6480464 27-hydroxycholesterol results in increased expression of BACE1 protein CTD PMID:19126211 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of BACE1 mRNA CTD PMID:20188158 6-propyl-2-thiouracil decreases expression ISO RGD:2191 6480464 Propylthiouracil results in decreased expression of BACE1 mRNA CTD PMID:24780913 acrolein increases expression EXP 6480464 Acrolein results in increased expression of BACE1 protein CTD PMID:23296102 acrolein increases expression ISO RGD:2191 6480464 Acrolein results in increased expression of BACE1 protein CTD PMID:23296102 , PMID:29355571 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of BACE1 mRNA CTD PMID:19770486 aflatoxin B1 decreases expression ISO RGD:1606566 6480464 Aflatoxin B1 results in decreased expression of BACE1 mRNA CTD PMID:27153756 aflatoxin B1 increases methylation ISO RGD:1606566 6480464 Aflatoxin B1 results in increased methylation of BACE1 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO RGD:1606566 6480464 Aflatoxin B1 results in increased expression of BACE1 mRNA CTD PMID:21641981 alendronic acid multiple interactions EXP 6480464 Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 all-trans-retinoic acid affects localization ISO RGD:1606566 6480464 Tretinoin affects the localization of BACE1 protein CTD PMID:19476501 all-trans-retinoic acid increases expression ISO RGD:1606566 6480464 Tretinoin results in increased expression of BACE1 mRNA, Tretinoin results in increased expression of BACE1 protein CTD PMID:16279945 more ... all-trans-retinoic acid multiple interactions ISO RGD:2191 6480464 Tretinoin inhibits the reaction [Vitamin A affects the expression of BACE mRNA] CTD PMID:16530976 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of BACE1 mRNA, Tretinoin results in increased expression of BACE1 protein CTD PMID:19476501 all-trans-retinol multiple interactions ISO RGD:2191 6480464 Tretinoin inhibits the reaction [Vitamin A affects the expression of BACE mRNA] CTD PMID:16530976 all-trans-retinol affects expression ISO RGD:2191 6480464 Vitamin A affects the expression of BACE mRNA CTD PMID:16530976 aminoguanidine multiple interactions ISO RGD:1606566 6480464 pimagedine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA] CTD PMID:28242320 ammonium chloride affects expression ISO RGD:2191 6480464 Ammonium Chloride affects the expression of BACE1 mRNA CTD PMID:16483693 arsane increases activity ISO RGD:2191 6480464 Arsenic results in increased activity of BACE1 protein CTD PMID:29155576 arsane multiple interactions ISO RGD:2191 6480464 [Arsenic co-treated with Cadmium co-treated with Lead] promotes the reaction [BACE1 protein results in increased metabolism of APP protein] CTD PMID:25288670 arsenic atom increases activity ISO RGD:2191 6480464 Arsenic results in increased activity of BACE1 protein CTD PMID:29155576 arsenic atom multiple interactions ISO RGD:2191 6480464 [Arsenic co-treated with Cadmium co-treated with Lead] promotes the reaction [BACE1 protein results in increased metabolism of APP protein] CTD PMID:25288670 arsenous acid decreases expression ISO RGD:1606566 6480464 Arsenic Trioxide results in decreased expression of BACE1 mRNA CTD PMID:22521957 azure B decreases activity ISO RGD:1606566 6480464 Azure B results in decreased activity of BACE1 protein CTD PMID:30500345 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of BACE1 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1606566 6480464 7 more ... CTD PMID:26238291 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 bisphenol A decreases expression ISO RGD:2191 6480464 bisphenol A results in decreased expression of BACE1 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:2191 6480464 bisphenol A results in increased expression of BACE1 mRNA CTD PMID:29097150 , PMID:30816183 butanal decreases expression ISO RGD:1606566 6480464 butyraldehyde results in decreased expression of BACE1 mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO RGD:2191 6480464 [Arsenic co-treated with Cadmium co-treated with Lead] promotes the reaction [BACE1 protein results in increased metabolism of APP protein] CTD PMID:25288670 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of BACE1 mRNA CTD PMID:25620056 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BACE1 gene CTD PMID:20938992 chromium(6+) affects expression ISO RGD:1606566 6480464 chromium hexavalent ion affects the expression of BACE1 mRNA CTD PMID:30690063 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of BACE1 mRNA CTD PMID:23811191 copper atom multiple interactions ISO RGD:1606566 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Copper results in increased expression of BACE1 mRNA] more ... CTD PMID:18583042 copper atom increases expression ISO RGD:1606566 6480464 Copper results in increased expression of BACE1 mRNA CTD PMID:18583042 copper(0) multiple interactions ISO RGD:1606566 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Copper results in increased expression of BACE1 mRNA] more ... CTD PMID:18583042 copper(0) increases expression ISO RGD:1606566 6480464 Copper results in increased expression of BACE1 mRNA CTD PMID:18583042 copper(II) chloride increases expression ISO RGD:2191 6480464 cupric chloride results in increased expression of BACE1 mRNA, cupric chloride results in increased expression of BACE1 protein CTD PMID:22542740 coumestrol multiple interactions ISO RGD:1606566 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BACE1 mRNA CTD PMID:19167446 curcumin multiple interactions ISO RGD:1606566 6480464 Curcumin inhibits the reaction [Copper results in increased expression of BACE1 mRNA], Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of BACE1 mRNA] CTD PMID:18583042 , PMID:31521693 curcumin increases expression ISO RGD:1606566 6480464 Curcumin results in increased expression of BACE1 mRNA CTD PMID:31521693 cyclosporin A decreases expression ISO RGD:1606566 6480464 Cyclosporine results in decreased expression of BACE1 mRNA CTD PMID:20106945 DDE multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 DDT increases expression ISO RGD:1606566 6480464 DDT results in increased expression of BACE1 CTD PMID:25720399 dexamethasone multiple interactions ISO RGD:2191 6480464 [APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA more ... CTD PMID:22484447 diarsenic trioxide decreases expression ISO RGD:1606566 6480464 Arsenic Trioxide results in decreased expression of BACE1 mRNA CTD PMID:22521957 dibutyl phthalate multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 diethyldithiocarbamic acid multiple interactions ISO RGD:1606566 6480464 Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA] CTD PMID:28242320 Dinophysistoxin 1 decreases expression ISO RGD:1606566 6480464 dinophysistoxin 1 results in decreased expression of BACE1 mRNA CTD PMID:28939011 dioxygen multiple interactions ISO RGD:1606566 6480464 alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] more ... CTD PMID:19196431 dioxygen increases expression ISO RGD:1606566 6480464 Oxygen deficiency results in increased expression of BACE1 mRNA, Oxygen deficiency results in increased expression of BACE1 protein CTD PMID:19196431 donepezil hydrochloride multiple interactions EXP 6480464 Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 dorsomorphin multiple interactions ISO RGD:1606566 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Enterolactone multiple interactions ISO RGD:1606566 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BACE1 mRNA CTD PMID:19167446 entinostat multiple interactions ISO RGD:1606566 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BACE1 mRNA CTD PMID:27188386 entinostat decreases expression ISO RGD:1606566 6480464 entinostat results in decreased expression of BACE1 mRNA CTD PMID:26272509 epoxiconazole multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of BACE1 mRNA CTD PMID:30319688 ferulic acid multiple interactions ISO RGD:1606566 6480464 ferulic acid inhibits the reaction [Copper results in increased expression of BACE1 mRNA] CTD PMID:18583042 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BACE1 gene CTD PMID:20938992 furan decreases expression ISO RGD:2191 6480464 furan results in decreased expression of BACE1 mRNA CTD PMID:25539665 genistein multiple interactions ISO RGD:2191 6480464 Genistein inhibits the reaction [aluminum chloride results in increased expression of BACE1 mRNA] CTD PMID:28552514 gentamycin decreases expression ISO RGD:2191 6480464 Gentamicins results in decreased expression of BACE mRNA CTD PMID:22061828 ginsenoside Rg1 multiple interactions ISO RGD:2191 6480464 ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA] CTD PMID:22484447 Goe 6976 multiple interactions ISO RGD:1606566 6480464 Go 6976 inhibits the reaction [Phorbol 12, 13-Dibutyrate affects the localization of BACE1 protein] CTD PMID:19476501 gold atom multiple interactions EXP 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA CTD PMID:19695318 gold(0) multiple interactions EXP 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA CTD PMID:19695318 hydrogen peroxide multiple interactions ISO RGD:1606566 6480464 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in increased expression of BACE1 mRNA], Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of BACE1 mRNA] CTD PMID:31521693 hydrogen peroxide increases expression ISO RGD:1606566 6480464 Hydrogen Peroxide results in increased expression of BACE1 mRNA CTD PMID:31521693 hypochlorous acid decreases expression EXP 6480464 Hypochlorous Acid results in decreased expression of BACE1 mRNA CTD PMID:19376150 ibuprofen multiple interactions ISO RGD:1606566 6480464 GW0072 inhibits the reaction [Ibuprofen inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of BACE1 mRNA]] more ... CTD PMID:14586007 ibuprofen decreases expression ISO RGD:2191 6480464 Ibuprofen results in decreased expression of BACE1 mRNA CTD PMID:16407166 ibuprofen decreases expression EXP 6480464 Ibuprofen results in decreased expression of BACE1 mRNA CTD PMID:16407166 ibuprofen multiple interactions EXP 6480464 GW0072 inhibits the reaction [Ibuprofen results in decreased expression of BACE1 mRNA] CTD PMID:16407166 ibuprofen decreases expression ISO RGD:1606566 6480464 Ibuprofen results in decreased expression of BACE1 mRNA CTD PMID:14586007 ibuprofen decreases activity ISO RGD:1606566 6480464 Ibuprofen results in decreased activity of BACE1 protein CTD PMID:14586007 icariin multiple interactions ISO RGD:2191 6480464 icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA] CTD PMID:19782061 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of BACE1 mRNA CTD PMID:16407166 indometacin multiple interactions ISO RGD:1606566 6480464 GW0072 inhibits the reaction [Indomethacin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of BACE1 mRNA]] CTD PMID:14586007 isoflurane increases expression ISO RGD:1606566 6480464 Isoflurane results in increased expression of BACE1 protein CTD PMID:17287498 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BACE1 gene CTD PMID:20938992 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of BACE1 mRNA, lead acetate results in increased expression of BACE1 protein CTD PMID:23867794 lead diacetate increases expression ISO RGD:2191 6480464 lead acetate results in increased expression of BACE1 protein CTD PMID:29908845 lead(0) increases expression ISO RGD:1606566 6480464 Lead results in increased expression of BACE1 protein CTD PMID:22272629 lead(0) multiple interactions ISO RGD:2191 6480464 [Arsenic co-treated with Cadmium co-treated with Lead] promotes the reaction [BACE1 protein results in increased metabolism of APP protein] CTD PMID:25288670 lead(2+) increases expression ISO RGD:1606566 6480464 Lead results in increased expression of BACE1 protein CTD PMID:22272629 lead(2+) multiple interactions ISO RGD:2191 6480464 [Arsenic co-treated with Cadmium co-treated with Lead] promotes the reaction [BACE1 protein results in increased metabolism of APP protein] CTD PMID:25288670 linuron multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 lipopolysaccharide multiple interactions ISO RGD:1606566 6480464 [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA more ... CTD PMID:28242320 manganese atom increases expression ISO RGD:1606566 6480464 Manganese results in increased expression of BACE1 mRNA CTD PMID:18583042 manganese(0) increases expression ISO RGD:1606566 6480464 Manganese results in increased expression of BACE1 mRNA CTD PMID:18583042 methamphetamine increases expression ISO RGD:2191 6480464 Methamphetamine results in increased expression of BACE1 protein CTD PMID:30367931 methylmercury chloride decreases expression ISO RGD:1606566 6480464 methylmercuric chloride results in decreased expression of BACE1 mRNA CTD PMID:24118919 , PMID:28001369 minocycline multiple interactions ISO RGD:1606566 6480464 Minocycline inhibits the reaction [Copper results in increased expression of BACE1 mRNA] CTD PMID:18583042 naproxen decreases expression EXP 6480464 Naproxen results in decreased expression of BACE1 mRNA CTD PMID:16407166 paracetamol increases expression ISO RGD:1606566 6480464 Acetaminophen results in increased expression of BACE1 mRNA CTD PMID:22230336 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of BACE1 mRNA CTD PMID:23091169 phenylmercury acetate increases expression ISO RGD:1606566 6480464 Phenylmercuric Acetate results in increased expression of BACE1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1606566 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BACE1 mRNA CTD PMID:27188386 phorbol 12,13-dibutanoate multiple interactions ISO RGD:1606566 6480464 Go 6976 inhibits the reaction [Phorbol 12, 13-Dibutyrate affects the localization of BACE1 protein] CTD PMID:19476501 phorbol 12,13-dibutanoate affects localization ISO RGD:1606566 6480464 Phorbol 12, 13-Dibutyrate affects the localization of BACE1 protein CTD PMID:19476501 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1606566 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] CTD PMID:23541064 pioglitazone multiple interactions ISO RGD:1606566 6480464 pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein] CTD PMID:14586007 pioglitazone decreases expression EXP 6480464 pioglitazone results in decreased expression of BACE1 mRNA, pioglitazone results in decreased expression of BACE1 protein CTD PMID:15817521 , PMID:16407166 pioglitazone decreases activity ISO RGD:1606566 6480464 pioglitazone results in decreased activity of BACE1 protein CTD PMID:14586007 pioglitazone decreases expression ISO RGD:1606566 6480464 pioglitazone results in decreased expression of BACE1 mRNA CTD PMID:14586007 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of BACE1 mRNA CTD PMID:19710929 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of BACE1 mRNA CTD PMID:18301758 , PMID:23811191 potassium chromate increases expression ISO RGD:1606566 6480464 potassium chromate(VI) results in increased expression of BACE1 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1606566 6480464 potassium chromate(VI) results in decreased expression of BACE1 mRNA CTD PMID:22714537 potassium chromate multiple interactions ISO RGD:1606566 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of BACE1 mRNA CTD PMID:22079256 prochloraz multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 procymidone multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of BACE1 mRNA CTD PMID:21278054 quercetin decreases activity ISO RGD:1606566 6480464 Quercetin results in decreased activity of BACE1 protein CTD PMID:31194956 rotenone multiple interactions ISO RGD:1606566 6480464 Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 S-adenosyl-L-homocysteine increases expression EXP 6480464 S-Adenosylhomocysteine results in increased expression of BACE1 protein CTD PMID:19635394 SB 203580 multiple interactions ISO RGD:1606566 6480464 SB 203580 inhibits the reaction [Copper results in increased expression of BACE1 mRNA] CTD PMID:18583042 SB 431542 multiple interactions ISO RGD:1606566 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sevoflurane increases expression EXP 6480464 sevoflurane results in increased expression of BACE1 protein CTD PMID:19433662 sevoflurane increases expression ISO RGD:1606566 6480464 sevoflurane results in increased expression of BACE1 protein CTD PMID:19433662 silver atom decreases expression EXP 6480464 Silver results in decreased expression of BACE1 mRNA CTD PMID:27131904 silver(0) decreases expression EXP 6480464 Silver results in decreased expression of BACE1 mRNA CTD PMID:27131904 sodium arsenite increases expression ISO RGD:1606566 6480464 sodium arsenite results in increased expression of BACE1 mRNA CTD PMID:17879257 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of BACE1 protein CTD PMID:30481507 streptozocin multiple interactions EXP 6480464 Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein], Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 sunitinib increases expression ISO RGD:1606566 6480464 Sunitinib results in increased expression of BACE1 mRNA CTD PMID:31533062 thimerosal decreases expression ISO RGD:1606566 6480464 Thimerosal results in decreased expression of BACE1 mRNA CTD PMID:27188386 thioacetamide decreases expression ISO RGD:2191 6480464 Thioacetamide results in decreased expression of BACE1 mRNA CTD PMID:23411599 tolfenamic acid decreases expression EXP 6480464 tolfenamic acid results in decreased expression of BACE1 mRNA, tolfenamic acid results in decreased expression of BACE1 protein CTD PMID:24462621 trichloroethene increases methylation ISO RGD:2191 6480464 Trichloroethylene results in increased methylation of BACE1 gene CTD PMID:27618143 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of BACE1 mRNA CTD PMID:28973697 uranium atom affects expression ISO RGD:1606566 6480464 Uranium affects the expression of BACE mRNA CTD PMID:15672453 valproic acid affects expression ISO RGD:1606566 6480464 Valproic Acid affects the expression of BACE1 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:1606566 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BACE1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1606566 6480464 Valproic Acid results in increased expression of BACE1 mRNA CTD PMID:23179753 more ... vinclozolin multiple interactions ISO RGD:2191 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 vinclozolin affects expression ISO RGD:2191 6480464 vinclozolin affects the expression of BACE1 mRNA CTD PMID:19015723 vitamin E multiple interactions ISO RGD:1606566 6480464 alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 vorinostat decreases expression ISO RGD:1606566 6480464 vorinostat results in decreased expression of BACE1 mRNA CTD PMID:27188386 zinc diethyldithiocarbamate multiple interactions ISO RGD:1606566 6480464 Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA] CTD PMID:28242320
Biological Process amyloid precursor protein catabolic process IGI UniProtKB:Q9BZC7 2290270 (MGI:MGI:6356260, PMID:20704561) ARUK-UCL MGI:MGI:6356260 , PMID:20704561 amyloid-beta metabolic process ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 amyloid-beta metabolic process IBA PANTHER:PTN002299446 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 amyloid-beta metabolic process IDA 2290270 (MGI:MGI:5751042, PMID:25592972) MGI MGI:MGI:5751042 , PMID:25592972 amyloid-beta metabolic process ISO RGD:2191 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 detection of mechanical stimulus involved in sensory perception of pain ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 membrane protein ectodomain proteolysis ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 membrane protein ectodomain proteolysis IBA PANTHER:PTN002299446 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 membrane protein ectodomain proteolysis IMP 2290270 (MGI:MGI:6316502, PMID:29325091) UniProt MGI:MGI:6316502 , PMID:29325091 memory TAS 2290270 (MGI:MGI:5825427, PMID:19118188) ARUK-UCL MGI:MGI:5825427 , PMID:19118188 modulation of chemical synaptic transmission TAS 2290270 (MGI:MGI:5819343, PMID:20943921) ARUK-UCL MGI:MGI:5819343 , PMID:20943921 modulation of chemical synaptic transmission IGI UniProtKB:P49582 2290270 (MGI:MGI:5819343, PMID:20943921) ARUK-UCL MGI:MGI:5819343 , PMID:20943921 positive regulation of neuron apoptotic process ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 prepulse inhibition ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 protein catabolic process IBA CGD:CAL0000201569, PANTHER:PTN000342793 2290270 (PMID:21873635) GO_Central PMID:21873635 proteolysis IDA 2290270 (MGI:MGI:3047450, PMID:15123597) MGI MGI:MGI:3047450 , PMID:15123597 proteolysis IBA CGD:CAL0000190503 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 proteolysis ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of synaptic plasticity TAS 2290270 (MGI:MGI:5825427, PMID:19118188) ARUK-UCL MGI:MGI:5825427 , PMID:19118188 regulation of synaptic vesicle exocytosis IMP 2290270 (MGI:MGI:3806404, PMID:18753368) MGI MGI:MGI:3806404 , PMID:18753368 Cellular Component axon IDA 2290270 (MGI:MGI:2154812, PMID:11740561) MGI MGI:MGI:2154812 , PMID:11740561 axon ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 cell projection IEA UniProtKB-KW:KW-0966 2290270 UniProt GO_REF:0000004, MGI:MGI:1354194 cell surface ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 cell surface IDA 2290270 (MGI:MGI:5816436, PMID:26467158) MGI MGI:MGI:5816436 , PMID:26467158 cytoplasmic vesicle IDA 2290270 (MGI:MGI:2154812, PMID:11740561) MGI MGI:MGI:2154812 , PMID:11740561 dendrite ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 early endosome ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 early endosome IDA 2290270 (MGI:MGI:5751042, PMID:25592972) MGI MGI:MGI:5751042 , PMID:25592972 endoplasmic reticulum IEA UniProtKB-KW:KW-0256 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 endosome ISO RGD:2191 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 endosome IBA MGI:MGI:1346542 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 endosome IDA 2290270 (MGI:MGI:5780539, PMID:19074428) UniProtKB MGI:MGI:5780539 , PMID:19074428 endosome ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Golgi apparatus ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Golgi apparatus IBA MGI:MGI:1346542 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 Golgi apparatus ISO RGD:2191 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 hippocampal mossy fiber to CA3 synapse IMP 2290270 (MGI:MGI:3806404, PMID:18753368) SynGO MGI:MGI:3806404 , PMID:18753368 hippocampal mossy fiber to CA3 synapse IDA 2290270 (MGI:MGI:6189350, PMID:23820808) SynGO MGI:MGI:6189350 , PMID:23820808 integral component of membrane IEA InterPro:IPR009119 , InterPro:IPR009120 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 integral component of membrane IEA UniProtKB-KW:KW-0812 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 integral component of plasma membrane ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 late endosome ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 lysosome ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 membrane IDA 2290270 (MGI:MGI:3589713, PMID:15886206) MGI MGI:MGI:3589713 , PMID:15886206 membrane IBA MGI:MGI:1346542 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 multivesicular body ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 neuronal cell body ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 plasma membrane ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 plasma membrane IDA 2290270 (MGI:MGI:6316502, PMID:29325091) UniProt MGI:MGI:6316502 , PMID:29325091 presynapse IDA 2290270 (MGI:MGI:6189350, PMID:23820808) MGI MGI:MGI:6189350 , PMID:23820808 recycling endosome ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 recycling endosome IDA 2290270 (MGI:MGI:6241579, PMID:23931995) UniProt MGI:MGI:6241579 , PMID:23931995 synaptic vesicle ISO RGD:2191 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 trans-Golgi network ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 trans-Golgi network IBA MGI:MGI:1346542 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 trans-Golgi network IDA 2290270 (MGI:MGI:5780539, PMID:19074428) UniProtKB MGI:MGI:5780539 , PMID:19074428 Molecular Function amyloid-beta binding ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 aspartic-type endopeptidase activity ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 aspartic-type endopeptidase activity IDA 2290270 (MGI:MGI:5751042, PMID:25592972) MGI MGI:MGI:5751042 , PMID:25592972 aspartic-type endopeptidase activity IMP 2290270 (MGI:MGI:6316502, PMID:29325091) UniProt MGI:MGI:6316502 , PMID:29325091 aspartic-type endopeptidase activity IBA CGD:CAL0000196689 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 endopeptidase activity IDA 2290270 (MGI:MGI:3047450, PMID:15123597) MGI MGI:MGI:3047450 , PMID:15123597 endopeptidase activity ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 enzyme binding ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 hydrolase activity IEA UniProtKB-KW:KW-0378 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 peptidase activity ISO RGD:2191 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 peptidase activity ISO UniProtKB:P56817 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein binding IPI UniProtKB:O95415 2290270 (MGI:MGI:3526749, PMID:15606899) MGI MGI:MGI:3526749 , PMID:15606899 protein binding IPI UniProtKB:O35598 2290270 (MGI:MGI:6316502, PMID:29325091) UniProt MGI:MGI:6316502 , PMID:29325091
Gene-Chemical Interaction Annotations
