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Gene: Pde1a (phosphodiesterase 1A, calmodulin-dependent) Mus musculus
Symbol: Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Description: Exhibits calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cGMP catabolic process; regulation of smooth muscle cell apoptotic process; and regulation of smooth muscle cell proliferation. Predicted to localize to cytoplasm; neuronal cell body; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PDE1A (phosphodiesterase 1A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 61 kDa Cam-PDE; AI987702; AW125737; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; cam-PDE 1A; MGC116577
Homo sapiens (human) : PDE1A (phosphodiesterase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde1a (phosphodiesterase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde1a (phosphodiesterase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE1A (phosphodiesterase 1A)
Canis lupus familiaris (dog) : PDE1A (phosphodiesterase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde1a (phosphodiesterase 1A)
Sus scrofa (pig) : PDE1A (phosphodiesterase 1A)
Chlorocebus sabaeus (African green monkey) : PDE1A (phosphodiesterase 1A)
Heterocephalus glaber (naked mole-rat) : Pde1a (phosphodiesterase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl279,834,453 - 80,129,458 (-)EnsemblGRCm38mm10GRCm38
GRCm38279,834,453 - 80,196,522 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37279,674,610 - 79,969,569 (-)NCBIGRCm37mm9NCBIm37
MGSCv36279,635,295 - 79,929,810 (-)NCBImm8
Celera281,494,586 - 81,789,784 (-)NCBICelera
Cytogenetic Map2C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pde1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68459
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.