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Gene: Pde1a (phosphodiesterase 1A, calmodulin-dependent) Mus musculus
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Symbol: Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Description: Exhibits calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cGMP catabolic process; regulation of smooth muscle cell apoptotic process; and regulation of smooth muscle cell proliferation. Predicted to localize to cytoplasm; neuronal cell body; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PDE1A (phosphodiesterase 1A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 61 kDa Cam-PDE; AI987702; AW125737; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; cam-PDE 1A; MGC116577
Orthologs:
Homo sapiens (human) : PDE1A (phosphodiesterase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde1a (phosphodiesterase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde1a (phosphodiesterase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE1A (phosphodiesterase 1A)
Canis lupus familiaris (dog) : PDE1A (phosphodiesterase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde1a (phosphodiesterase 1A)
Sus scrofa (pig) : PDE1A (phosphodiesterase 1A)
Chlorocebus sabaeus (African green monkey) : PDE1A (phosphodiesterase 1A)
Heterocephalus glaber (naked mole-rat) : Pde1a (phosphodiesterase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl279,834,453 - 80,129,458 (-)EnsemblGRCm38mm10GRCm38
GRCm38279,834,453 - 80,196,522 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37279,674,610 - 79,969,569 (-)NCBIGRCm37mm9NCBIm37
MGSCv36279,635,295 - 79,929,810 (-)NCBImm8
Celera281,494,586 - 81,789,784 (-)NCBICelera
Cytogenetic Map2C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pde1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68459
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.