Ghsr (growth hormone secretagogue receptor) - Rat Genome Database

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Gene: Ghsr (growth hormone secretagogue receptor) Mus musculus
Analyze
Symbol: Ghsr
Name: growth hormone secretagogue receptor
RGD ID: 737310
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor activity; identical protein binding activity; and peptide hormone binding activity. Involved in adult feeding behavior and positive regulation of appetite. Acts upstream of or within several processes, including cellular response to insulin stimulus; growth hormone secretion; and positive regulation of insulin-like growth factor receptor signaling pathway. Predicted to be located in cell surface; membrane raft; and neuron projection. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; and trachea. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C530020I22Rik; G-protein coupled receptor; GH-releasing peptide receptor; ghrelin receptor; GHRP; Ghs; GHS-R; Ghsr1a; growth hormone secretagogue receptor type 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39327,425,500 - 27,433,384 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl327,425,500 - 27,432,159 (+)EnsemblGRCm39 Ensembl
GRCm38327,371,351 - 27,379,235 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl327,371,351 - 27,378,010 (+)EnsemblGRCm38mm10GRCm38
MGSCv37327,270,273 - 27,276,932 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36327,562,424 - 27,569,083 (+)NCBIMGSCv36mm8
Celera327,331,821 - 27,338,480 (+)NCBICelera
Cytogenetic Map3A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin polymerization or depolymerization  (ISO)
adult feeding behavior  (IMP)
cellular response to insulin stimulus  (IDA)
cellular response to insulin-like growth factor stimulus  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to thyroid hormone stimulus  (ISO)
decidualization  (ISO)
female pregnancy  (ISO)
G protein-coupled receptor signaling pathway  (IBA,ISO)
ghrelin secretion  (ISO)
growth hormone secretion  (IGI)
hormone-mediated signaling pathway  (IBA,ISO)
insulin-like growth factor receptor signaling pathway  (IMP)
learning or memory  (ISO)
negative regulation of appetite  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of interleukin-1 beta production  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of locomotion involved in locomotory behavior  (ISO)
negative regulation of macrophage apoptotic process  (ISO)
negative regulation of norepinephrine secretion  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
positive regulation of appetite  (IMP)
positive regulation of eating behavior  (ISO)
positive regulation of fatty acid metabolic process  (ISO)
positive regulation of growth  (ISO)
positive regulation of insulin-like growth factor receptor signaling pathway  (IMP)
positive regulation of multicellular organism growth  (ISO)
positive regulation of small intestinal transit  (ISO)
positive regulation of small intestine smooth muscle contraction  (ISO)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of vascular endothelial cell proliferation  (ISO)
postsynaptic modulation of chemical synaptic transmission  (ISO)
regulation of feeding behavior  (ISO)
regulation of gastric motility  (ISO)
regulation of growth hormone secretion  (ISO)
regulation of hindgut contraction  (ISO)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane  (ISO)
regulation of postsynapse organization  (ISO)
regulation of synapse assembly  (IMP)
regulation of transmission of nerve impulse  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to follicle-stimulating hormone  (ISO)
response to food  (IDA)
response to growth hormone  (ISO)
response to hormone  (ISO)
response to monosodium glutamate  (ISO)
signal transduction  (IEA)
spermatogenesis  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype. Banerjee SA, etal., Brain Res Mol Brain Res. 1994 Jul;24(1-4):89-106.
2. Growth hormone secretagogue receptor deficiency in mice protects against obesity-induced hypertension. Harris LE, etal., Physiol Rep. 2014 Mar 20;2(3):e00240. doi: 10.1002/phy2.240. Print 2014.
3. Ghrelin receptor mutations--too little height and too much hunger. Holst B and Schwartz TW, J Clin Invest. 2006 Mar;116(3):637-41.
4. Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. Hwang S, etal., Endocr J. 2009;56(4):609-17. Epub 2009 Apr 7.
5. Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature. Inoue H, etal., J Clin Endocrinol Metab. 2011 Feb;96(2):E373-8. doi: 10.1210/jc.2010-1570. Epub 2010 Nov 17.
6. Growth hormone-dependent regulation of pituitary GH secretagogue receptor (GHS-R) mRNA levels in the spontaneous dwarf Rat. Kamegai J, etal., Neuroendocrinology. 1998 Nov;68(5):312-8.
7. Ghrelin: structure and function. Kojima M and Kangawa K, Physiol Rev. 2005 Apr;85(2):495-522.
8. Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury. Lee JY, etal., Biochim Biophys Acta. 2014 Dec;1842(12 Pt A):2403-12. doi: 10.1016/j.bbadis.2014.09.006. Epub 2014 Sep 28.
9. Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats. Li L, etal., Acta Pharmacol Sin. 2006 May;27(5):527-35.
10. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats. Miao Y, etal., Biochem Biophys Res Commun. 2007 Aug 3;359(3):795-800. Epub 2007 Jun 6.
14. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. Mouse MP Annotation Import Pipeline RGD automated import pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Orexin Plays a Role in Growth Impediment Induced by Obstructive Sleep Breathing in Rats. Tarasiuk A, etal., Sleep. 2016 Apr 1;39(4):887-97. doi: 10.5665/sleep.5648.
20. Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity. Wiedemann T, etal., Diabetes. 2016 Feb;65(2):406-20. doi: 10.2337/db15-0374. Epub 2015 Oct 28.
21. Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis. Wu R, etal., Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1296-302. Epub 2004 May 20.
22. Effects of ghrelin on gastric distention sensitive neurons in the arcuate nucleus of hypothalamus and gastric motility in diabetic rats. Xu L, etal., Peptides. 2013 Oct;48:137-46. doi: 10.1016/j.peptides.2013.08.010. Epub 2013 Aug 18.
23. [Relationship between Ghrelin and growth hormone secretagogue receptor expression and catch-up growth in rats with intrauterine growth restriction]. Yang HM, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jul;12(7):563-8.
24. Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a. Zaniolo K, etal., Invest Ophthalmol Vis Sci. 2011 Jul 23;52(8):5376-86. doi: 10.1167/iovs.10-7152.
25. Acylated ghrelin protects hippocampal neurons in pilocarpine-induced seizures of immature rats by inhibiting cell apoptosis. Zhang R, etal., Mol Biol Rep. 2013 Jan;40(1):51-8. doi: 10.1007/s11033-012-1993-1. Epub 2012 Nov 6.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12679517   PMID:12746326   PMID:14701677   PMID:14962995   PMID:14996723   PMID:15070777   PMID:16141072  
PMID:16141073   PMID:16322794   PMID:16484324   PMID:16491079   PMID:16513828   PMID:16601073   PMID:16602821   PMID:17060947   PMID:17130496   PMID:17158206   PMID:17251274   PMID:17823656  
PMID:18006636   PMID:18048479   PMID:18202139   PMID:18287559   PMID:18552842   PMID:18602461   PMID:18657539   PMID:18668043   PMID:19054770   PMID:19299444   PMID:19299626   PMID:19564604  
PMID:19633195   PMID:19666088   PMID:19666521   PMID:19824771   PMID:19906954   PMID:20034618   PMID:20060438   PMID:20515700   PMID:20526334   PMID:20597975   PMID:20668691   PMID:20856820  
PMID:20933579   PMID:21036184   PMID:21037584   PMID:21054685   PMID:21211044   PMID:21245306   PMID:21267068   PMID:21298106   PMID:21674492   PMID:21701068   PMID:21873635   PMID:21874246  
PMID:21895961   PMID:21940628   PMID:21963822   PMID:22119755   PMID:22211783   PMID:22284186   PMID:22338071   PMID:22363801   PMID:22391948   PMID:22407166   PMID:22484009   PMID:22538519  
PMID:22641088   PMID:22649381   PMID:22669248   PMID:22700774   PMID:22865372   PMID:22952883   PMID:22962259   PMID:23020201   PMID:23063723   PMID:23128468   PMID:23178796   PMID:23281394  
PMID:23341196   PMID:23736537   PMID:23804489   PMID:23998356   PMID:24040441   PMID:24062249   PMID:24134163   PMID:24194600   PMID:24285267   PMID:24473434   PMID:24567905   PMID:24735326  
PMID:24747517   PMID:24825838   PMID:24952961   PMID:25060361   PMID:25157160   PMID:25211592   PMID:25322462   PMID:25329803   PMID:25447526   PMID:25553467   PMID:25631345   PMID:25658305  
PMID:25727097   PMID:25737953   PMID:25825652   PMID:25828736   PMID:26003495   PMID:26279396   PMID:26283199   PMID:26357899   PMID:26370322   PMID:26460782   PMID:26490687   PMID:26577678  
PMID:26590421   PMID:26791525   PMID:26812158   PMID:26837433   PMID:27207529   PMID:27404127   PMID:27626380   PMID:28204197   PMID:28338217   PMID:28361877   PMID:28409695   PMID:28420089  
PMID:28487437   PMID:28542403   PMID:28700664   PMID:28752052   PMID:28959025   PMID:28993142   PMID:29063591   PMID:29155981   PMID:29300858   PMID:29396372   PMID:29458391   PMID:29688375  
PMID:29761230   PMID:29802915   PMID:30199095   PMID:30204871   PMID:30380028   PMID:30405536   PMID:31057357   PMID:31105045   PMID:31179562   PMID:31185255   PMID:31201280   PMID:31251830  
PMID:31413143   PMID:31520709   PMID:31542636   PMID:31748785   PMID:31790138   PMID:31942916   PMID:32339772   PMID:32535402   PMID:32750410   PMID:32934774   PMID:33116243   PMID:33368660  
PMID:33593997   PMID:33774644   PMID:33788980   PMID:33793646   PMID:33798772   PMID:33879778   PMID:33913930   PMID:33920473   PMID:34264027   PMID:34289060   PMID:34478806   PMID:34641940  
PMID:34742928   PMID:34845505   PMID:34929449   PMID:34971379   PMID:35159134   PMID:35204795   PMID:35239443   PMID:35290931   PMID:35327599   PMID:35504998   PMID:35650438   PMID:36011279  
PMID:36291579  


Genomics

Comparative Map Data
Ghsr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39327,425,500 - 27,433,384 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl327,425,500 - 27,432,159 (+)EnsemblGRCm39 Ensembl
GRCm38327,371,351 - 27,379,235 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl327,371,351 - 27,378,010 (+)EnsemblGRCm38mm10GRCm38
MGSCv37327,270,273 - 27,276,932 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36327,562,424 - 27,569,083 (+)NCBIMGSCv36mm8
Celera327,331,821 - 27,338,480 (+)NCBICelera
Cytogenetic Map3A3NCBI
GHSR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383172,443,291 - 172,448,456 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3172,443,291 - 172,448,456 (-)EnsemblGRCh38hg38GRCh38
GRCh373172,161,081 - 172,166,246 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363173,645,645 - 173,648,897 (-)NCBINCBI36Build 36hg18NCBI36
Build 343173,648,035 - 173,648,905NCBI
Celera3170,559,676 - 170,564,839 (-)NCBICelera
Cytogenetic Map3q26.31NCBI
HuRef3169,531,507 - 169,536,581 (-)NCBIHuRef
CHM1_13172,123,965 - 172,129,130 (-)NCBICHM1_1
T2T-CHM13v2.03175,228,381 - 175,233,536 (-)NCBIT2T-CHM13v2.0
Ghsr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22110,268,489 - 110,271,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2110,268,489 - 110,271,865 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2116,922,519 - 116,925,893 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02115,035,078 - 115,038,452 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02109,749,447 - 109,752,824 (+)NCBIRnor_WKY
Rnor_6.02113,065,953 - 113,071,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2113,066,885 - 113,070,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02132,784,207 - 132,789,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42113,269,623 - 113,272,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12113,214,584 - 113,217,961 (+)NCBI
Celera2105,470,925 - 105,474,301 (+)NCBICelera
Cytogenetic Map2q24NCBI
Ghsr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554202,478,877 - 2,487,215 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554202,483,173 - 2,486,414 (-)NCBIChiLan1.0ChiLan1.0
GHSR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13177,633,039 - 177,638,202 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3177,633,039 - 177,638,202 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03169,448,217 - 169,458,602 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GHSR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13436,691,132 - 36,694,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3436,690,224 - 36,694,312 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3445,703,894 - 45,707,255 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03436,775,648 - 36,779,007 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3436,774,740 - 36,779,009 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13436,714,573 - 36,717,930 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03436,683,080 - 36,686,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03436,941,135 - 36,944,502 (-)NCBIUU_Cfam_GSD_1.0
Ghsr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602103,348,347 - 103,353,683 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936593268,350 - 277,229 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936593268,736 - 273,623 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHSR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13110,983,298 - 111,038,324 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113110,981,465 - 111,006,149 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213119,917,068 - 119,929,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GHSR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11517,008,185 - 17,013,504 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1517,009,369 - 17,012,618 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606325,770,911 - 25,777,537 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ghsr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473050,488,887 - 50,492,405 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473050,484,763 - 50,492,443 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:928
Count of miRNA genes:528
Interacting mature miRNAs:646
Transcripts:ENSMUST00000057186
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32476823231332103Mouse
13432186Rotse1_mrotarod training saline/ethanol 1 (mouse)32665522728355227Mouse

Markers in Region
33.MMHAP61FRC12.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38327,373,177 - 27,373,338UniSTSGRCm38
MGSCv37327,272,099 - 27,272,260UniSTSGRCm37
Celera327,333,647 - 27,333,808UniSTS
Cytogenetic Map3A3UniSTS
Whitehead_YAC3 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000057186   ⟹   ENSMUSP00000061153
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl327,425,500 - 27,432,159 (+)Ensembl
GRCm38.p6 Ensembl327,371,351 - 27,378,010 (+)Ensembl
RefSeq Acc Id: NM_177330   ⟹   NP_796304
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,425,500 - 27,432,159 (+)NCBI
GRCm38327,371,351 - 27,378,010 (+)NCBI
MGSCv37327,270,273 - 27,276,932 (+)RGD
Celera327,331,821 - 27,338,480 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017319513   ⟹   XP_017175002
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,425,604 - 27,433,384 (+)NCBI
GRCm38327,371,455 - 27,379,235 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_796304   ⟸   NM_177330
- UniProtKB: Q91Z82 (UniProtKB/Swiss-Prot),   Q99P50 (UniProtKB/Swiss-Prot),   Q0VBE5 (UniProtKB/TrEMBL),   A0A8C6HUE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017175002   ⟸   XM_017319513
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000061153   ⟸   ENSMUST00000057186
Protein Domains
G_PROTEIN_RECEP_F1_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99P50-F1-model_v2 AlphaFold Q99P50 1-364 view protein structure

Promoters
RGD ID:6880362
Promoter ID:EPDNEW_M3632
Type:single initiation site
Name:Ghsr_1
Description:Mus musculus growth hormone secretagogue receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38327,371,321 - 27,371,381EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2441906 AgrOrtholog
Ensembl Genes ENSMUSG00000051136 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000061153 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000057186 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro 7tmA_GHSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHS-R/MTLR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:208188 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2441906 ENTREZGENE
NCBI Gene 208188 ENTREZGENE
PANTHER PTHR24243:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ghsr PhenoGen
PRINTS GHSRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C6HUE1 ENTREZGENE
  GHSR_MOUSE UniProtKB/Swiss-Prot
  Q0VBE5 ENTREZGENE, UniProtKB/TrEMBL
  Q80UB2_MOUSE UniProtKB/TrEMBL
  Q91Z82 ENTREZGENE
  Q99P50 ENTREZGENE
UniProt Secondary Q8BWX8 UniProtKB/Swiss-Prot
  Q91Z82 UniProtKB/Swiss-Prot