Iqgap2 (IQ motif containing GTPase activating protein 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Iqgap2 (IQ motif containing GTPase activating protein 2) Mus musculus
Analyze
Symbol: Iqgap2
Name: IQ motif containing GTPase activating protein 2
RGD ID: 1621864
MGI Page MGI
Description: Predicted to enable several functions, including Arp2/3 complex binding activity; GTPase activator activity; and calmodulin binding activity. Predicted to be involved in actin filament organization; regulation of actin cytoskeleton organization; and thrombin-activated receptor signaling pathway. Located in microvillus. Is expressed in several structures, including alimentary system; axial skeleton; central nervous system; genitourinary system; and liver. Used to study hepatocellular carcinoma. Orthologous to human IQGAP2 (IQ motif containing GTPase activating protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4933417J23Rik; A630053O10; AI788777; expressed sequence AI788777; ras GTPase-activating-like protein IQGAP2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,763,685 - 96,028,788 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1395,763,682 - 96,028,991 (-)EnsemblGRCm39 Ensembl
GRCm381395,627,177 - 95,892,280 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,627,174 - 95,892,483 (-)EnsemblGRCm38mm10GRCm38
MGSCv371396,397,132 - 96,661,877 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361396,397,132 - 96,661,877 (-)NCBIMGSCv36mm8
Celera1399,243,963 - 99,510,431 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
clobetasol  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
ellagic acid  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
glyphosate  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
isoflavones  (ISO)
ivermectin  (ISO)
methidathion  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
ozone  (EXP)
paracetamol  (ISO)
parathion  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP)
phenol red  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triptonide  (EXP)
Tungsten carbide  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14516655   PMID:14610273   PMID:15457341  
PMID:16141072   PMID:16141073   PMID:16964442   PMID:16966370   PMID:18180285   PMID:18287559   PMID:18604197   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21931791   PMID:21968151  
PMID:22493426   PMID:23951254   PMID:24194600   PMID:24268772   PMID:24906954   PMID:26047140   PMID:26410627   PMID:26590968   PMID:27507650   PMID:27626380   PMID:28167789   PMID:28179424  
PMID:28378742   PMID:28671696   PMID:28706196   PMID:30457570   PMID:32325033   PMID:34321999   PMID:37805137  


Genomics

Comparative Map Data
Iqgap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,763,685 - 96,028,788 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1395,763,682 - 96,028,991 (-)EnsemblGRCm39 Ensembl
GRCm381395,627,177 - 95,892,280 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,627,174 - 95,892,483 (-)EnsemblGRCm38mm10GRCm38
MGSCv371396,397,132 - 96,661,877 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361396,397,132 - 96,661,877 (-)NCBIMGSCv36mm8
Celera1399,243,963 - 99,510,431 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.26NCBI
IQGAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38576,403,285 - 76,708,132 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl576,403,285 - 76,708,132 (+)EnsemblGRCh38hg38GRCh38
GRCh37575,699,110 - 76,003,957 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36575,734,905 - 76,039,713 (+)NCBINCBI36Build 36hg18NCBI36
Build 34575,734,904 - 76,039,711NCBI
Celera571,592,826 - 71,897,903 (+)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef570,906,692 - 71,211,466 (+)NCBIHuRef
CHM1_1575,131,847 - 75,437,149 (+)NCBICHM1_1
T2T-CHM13v2.0576,885,042 - 77,189,993 (+)NCBIT2T-CHM13v2.0
Iqgap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,629,558 - 28,904,649 (-)NCBIGRCr8
mRatBN7.2226,894,836 - 27,170,270 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,894,825 - 27,170,279 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0226,161,628 - 26,439,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl226,167,199 - 26,438,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0245,295,534 - 45,569,560 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,039,689 - 26,147,538 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera222,958,327 - 23,102,329 (-)NCBICelera
Cytogenetic Map2q12NCBI
Iqgap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542524,167,104 - 24,385,146 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542524,167,985 - 24,384,912 (-)NCBIChiLan1.0ChiLan1.0
IQGAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2438,597,137 - 38,902,374 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1536,750,767 - 37,056,000 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0538,593,574 - 38,900,327 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1539,137,539 - 39,516,894 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl539,138,359 - 39,516,596 (-)Ensemblpanpan1.1panPan2
IQGAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1329,894,192 - 30,134,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl329,894,870 - 30,174,259 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha331,132,907 - 31,420,147 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0329,818,056 - 30,105,892 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl329,818,467 - 30,106,093 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1329,749,579 - 30,036,702 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0329,730,444 - 30,016,347 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0330,099,810 - 30,387,253 (-)NCBIUU_Cfam_GSD_1.0
Iqgap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213190,317,091 - 190,603,571 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936549255,303 - 541,917 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936549256,097 - 541,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IQGAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl285,294,530 - 85,633,642 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1285,294,423 - 85,633,645 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2286,916,946 - 87,086,957 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IQGAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1470,672,171 - 70,979,766 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl470,672,553 - 70,979,763 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604919,502,207 - 19,811,126 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Iqgap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624869889,091 - 1,171,983 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624869888,868 - 1,172,747 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Iqgap2
11227 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:189
Count of miRNA genes:167
Interacting mature miRNAs:170
Transcripts:ENSMUST00000068603
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
12880402Emlq1_memotional learning QTL 1 (mouse)137810885896866553Mouse
12879495Fexq1_mfear expression QTL 1 (mouse)137826885895836553Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87901985112431103Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1395036824120883175Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395502130120883175Mouse

Markers in Region
Avpr1b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10D1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic MapXF1UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map13B2UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map7F2UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map10B5.1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map18B3UniSTS
cM Map1 UniSTS
Iqgap2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371396,431,401 - 96,431,675UniSTSGRCm37
Celera1399,278,367 - 99,278,641UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.01UniSTS
cM MapUN UniSTS
D13Mit145  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,824,704 - 95,824,847UniSTSGRCm38
MGSCv371396,594,659 - 96,594,802UniSTSGRCm37
Celera1399,440,020 - 99,440,163UniSTS
Cytogenetic Map13D1UniSTS
cM Map1352.0UniSTS
Whitehead Genetic1335.0UniSTS
Whitehead_YAC13 UniSTS
AI788777  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,627,290 - 95,627,392UniSTSGRCm38
MGSCv371396,397,245 - 96,397,347UniSTSGRCm37
Celera1399,244,076 - 99,244,179UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.01UniSTS
Whitehead/MRC_RH13829.41UniSTS
px-31f3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map13B2UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map10A3-A4UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B5UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map10C3UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map10B5.1UniSTS
Cytogenetic Map18E4UniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map18D1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map12C2UniSTS
Cytogenetic Map11E1UniSTS
cM MapX42.0UniSTS
cM Map1229.0UniSTS
cM Map1336.0UniSTS
cM Map154.6UniSTS
cM Map1170.0UniSTS
cM Map518.2UniSTS
cM Map1060.0UniSTS
cM Map1347.01UniSTS
cM Map439.4UniSTS
F2rl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,700,766 - 95,700,885UniSTSGRCm38
MGSCv371396,470,707 - 96,470,880UniSTSGRCm37
Celera1399,317,650 - 99,317,769UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.02UniSTS
cM Map1347.02UniSTS
cM Map1347.01UniSTS
D13Mit320  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,778,268 - 95,778,558UniSTSGRCm38
MGSCv371396,548,223 - 96,548,513UniSTSGRCm37
Celera1399,394,892 - 99,395,195UniSTS
Cytogenetic Map13D1UniSTS
cM Map13 UniSTS
MARC_17727-17728:1031758304:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,628,970 - 95,630,102UniSTSGRCm38
MGSCv371396,398,925 - 96,400,057UniSTSGRCm37
Cytogenetic Map13D1UniSTS
cM Map1347.01UniSTS
F2rl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,700,752 - 95,700,925UniSTSGRCm38
MGSCv371396,470,707 - 96,470,880UniSTSGRCm37
Celera1399,317,636 - 99,317,809UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.02UniSTS
Iqgap2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,661,446 - 95,661,720UniSTSGRCm38
MGSCv371396,431,401 - 96,431,675UniSTSGRCm37
Celera1399,278,367 - 99,278,641UniSTS
Cytogenetic Map13D1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_027711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC171003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ201339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000068603   ⟹   ENSMUSP00000067685
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,763,682 - 96,028,503 (-)Ensembl
GRCm38.p6 Ensembl1395,627,174 - 95,891,995 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,882,820 - 96,028,265 (-)Ensembl
GRCm38.p6 Ensembl1395,746,312 - 95,891,757 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238263
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,811,801 - 95,818,832 (-)Ensembl
GRCm38.p6 Ensembl1395,675,293 - 95,682,324 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238392
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,796,705 - 95,802,208 (-)Ensembl
GRCm38.p6 Ensembl1395,660,197 - 95,665,700 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238404
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,795,083 - 95,797,606 (-)Ensembl
GRCm38.p6 Ensembl1395,658,575 - 95,661,098 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,882,958 - 95,900,905 (-)Ensembl
GRCm38.p6 Ensembl1395,746,450 - 95,764,397 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238515
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,869,439 - 96,028,991 (-)Ensembl
GRCm38.p6 Ensembl1395,732,931 - 95,892,483 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238595
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,797,910 - 95,819,445 (-)Ensembl
GRCm38.p6 Ensembl1395,661,402 - 95,682,937 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238783
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1395,804,935 - 95,808,027 (-)Ensembl
GRCm38.p6 Ensembl1395,668,427 - 95,671,519 (-)Ensembl
RefSeq Acc Id: NM_027711   ⟹   NP_081987
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,763,685 - 96,028,430 (-)NCBI
GRCm381395,627,177 - 95,891,922 (-)NCBI
MGSCv371396,397,132 - 96,661,877 (-)RGD
Celera1399,243,963 - 99,510,431 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036158091   ⟹   XP_036013984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,763,685 - 96,028,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036158092   ⟹   XP_036013985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,763,685 - 96,028,788 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_081987   ⟸   NM_027711
- UniProtKB: Q3UQ44 (UniProtKB/Swiss-Prot),   B9EKK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000067685   ⟸   ENSMUST00000068603
RefSeq Acc Id: XP_036013985   ⟸   XM_036158092
- Peptide Label: isoform X2
- UniProtKB: B9EKK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036013984   ⟸   XM_036158091
- Peptide Label: isoform X1
- UniProtKB: B9EKK3 (UniProtKB/TrEMBL)
Protein Domains
Calponin-homology (CH)   IQ   Ras-GAP   RasGAP protein C-terminal   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UQ44-F1-model_v2 AlphaFold Q3UQ44 1-1575 view protein structure

Promoters
RGD ID:8681060
Promoter ID:EPDNEW_M18561
Type:initiation region
Name:Iqgap2_1
Description:Mus musculus IQ motif containing GTPase activating protein 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381395,891,917 - 95,891,977EPDNEW
RGD ID:6824074
Promoter ID:MM_KWN:14964
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell
Transcripts:NM_027711
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361396,661,821 - 96,662,321 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2449975 AgrOrtholog
Ensembl Genes ENSMUSG00000021676 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000068603 ENTREZGENE
  ENSMUST00000068603.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.418.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:544963 UniProtKB/Swiss-Prot
MGD MGI:2449975 ENTREZGENE
NCBI Gene 544963 ENTREZGENE
PANTHER RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00612 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Iqgap2 PhenoGen
PROSITE PS50021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00033 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RGC domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B9EKK3 ENTREZGENE, UniProtKB/TrEMBL
  IQGA2_MOUSE UniProtKB/Swiss-Prot
  Q3TU73_MOUSE UniProtKB/TrEMBL
  Q3UQ44 ENTREZGENE
  Q7TMU5_MOUSE UniProtKB/TrEMBL
  Q811L1_MOUSE UniProtKB/TrEMBL
  Q8BV47_MOUSE UniProtKB/TrEMBL
  Q8C9I3_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Iqgap2  IQ motif containing GTPase activating protein 2  AI788777  expressed sequence AI788777  Data merged from RGD:1607210 737654 PROVISIONAL