G3bp1 (G3BP stress granule assembly factor 1) - Rat Genome Database

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Gene: G3bp1 (G3BP stress granule assembly factor 1) Mus musculus
Analyze
Symbol: G3bp1
Name: G3BP stress granule assembly factor 1
RGD ID: 1557408
MGI Page MGI
Description: Enables mRNA binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway. Located in cytoplasmic stress granule. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI849976; ATP-dependent DNA helicase VIII; B430204O07; C87777; G3bp; G3BP-1; GAP SH3 binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; HDH-VIII; KIAA4115; mKIAA4115; ras GTPase-activating protein-binding protein 1; Ras-GTPase-activating protein SH3-domain binding protein 1; RP23-336J1.4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm14896   Gm5913   Gm7405   Gm9509  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,360,521 - 55,391,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,360,511 - 55,395,664 (+)EnsemblGRCm39 Ensembl
GRCm381155,469,657 - 55,500,888 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,469,685 - 55,504,838 (+)EnsemblGRCm38mm10GRCm38
MGSCv371155,283,254 - 55,314,389 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361155,313,175 - 55,344,310 (+)NCBIMGSCv36mm8
Celera1160,271,641 - 60,286,911 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acrolein  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP,ISO)
CGP 52608  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (EXP)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP)
diazinon  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
ethanol  (EXP)
fenthion  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
geldanamycin  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glyphosate  (EXP)
hexadecanoic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
lovastatin  (EXP)
mercury dichloride  (ISO)
methidathion  (EXP)
methotrexate  (EXP)
methyl methanesulfonate  (ISO)
microcystin RR  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
poly(I:C)  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
syringic acid  (EXP,ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
warfarin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytoplasmic stress granule  (IBA,IDA,ISO)
cytosol  (IBA,IEA,ISO)
nucleus  (IEA)
perikaryon  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8649363   PMID:8889548   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11604510   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:14681479   PMID:14729942   PMID:15086518   PMID:15226823   PMID:15489334   PMID:15782199   PMID:15840001   PMID:15886195   PMID:16033648   PMID:16141072   PMID:16141073  
PMID:16166649   PMID:17967808   PMID:18495661   PMID:18625844   PMID:18627790   PMID:18799693   PMID:18973680   PMID:21652632   PMID:21677750   PMID:21873635   PMID:22205990   PMID:22833567  
PMID:23087212   PMID:23230274   PMID:23373770   PMID:23604909   PMID:23665500   PMID:24194600   PMID:25651939   PMID:25962958   PMID:26265008   PMID:26675618   PMID:27022092   PMID:27430620  
PMID:27481264   PMID:27513819   PMID:28671696   PMID:29530978   PMID:29626090   PMID:29676259   PMID:30333137   PMID:30510222   PMID:31138677   PMID:31213553   PMID:31403400   PMID:31481451  
PMID:32325033   PMID:32434143   PMID:32535204   PMID:32554809   PMID:33065005   PMID:33601422   PMID:33941659   PMID:33945510   PMID:34133714   PMID:34296442   PMID:35652658   PMID:36417873  
PMID:36511898   PMID:36738734   PMID:37142655   PMID:37870259   PMID:38355793  


Genomics

Comparative Map Data
G3bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,360,521 - 55,391,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,360,511 - 55,395,664 (+)EnsemblGRCm39 Ensembl
GRCm381155,469,657 - 55,500,888 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,469,685 - 55,504,838 (+)EnsemblGRCm38mm10GRCm38
MGSCv371155,283,254 - 55,314,389 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361155,313,175 - 55,344,310 (+)NCBIMGSCv36mm8
Celera1160,271,641 - 60,286,911 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.09NCBI
G3BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385151,771,954 - 151,812,785 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5151,771,045 - 151,812,911 (+)EnsemblGRCh38hg38GRCh38
GRCh375151,151,515 - 151,192,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365151,131,669 - 151,165,108 (+)NCBINCBI36Build 36hg18NCBI36
Celera5147,232,867 - 147,266,308 (+)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5146,296,870 - 146,330,324 (+)NCBIHuRef
CHM1_15150,583,918 - 150,617,337 (+)NCBICHM1_1
T2T-CHM13v2.05152,310,934 - 152,351,769 (+)NCBIT2T-CHM13v2.0
G3bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,087,533 - 40,120,931 (+)NCBIGRCr8
mRatBN7.21039,586,864 - 39,620,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1039,586,864 - 39,620,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1044,270,665 - 44,304,038 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01043,760,770 - 43,794,148 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,264,441 - 39,297,820 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01040,812,858 - 40,846,252 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,812,858 - 40,846,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,644,334 - 40,678,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,880,198 - 40,913,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11040,922,239 - 40,922,700 (+)NCBI
Celera1038,918,605 - 38,949,887 (+)NCBICelera
Cytogenetic Map10q22NCBI
G3bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554086,197,361 - 6,215,979 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554086,197,988 - 6,223,135 (+)NCBIChiLan1.0ChiLan1.0
G3BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24147,000,002 - 147,033,451 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15145,139,497 - 145,172,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05147,195,100 - 147,234,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15153,197,988 - 153,237,329 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5153,197,813 - 153,230,414 (+)Ensemblpanpan1.1panPan2
G3BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1457,541,627 - 57,585,375 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl457,481,908 - 57,585,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha457,361,381 - 57,405,136 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0457,984,264 - 58,028,046 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl457,962,892 - 58,027,993 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1457,800,420 - 57,844,163 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0457,898,867 - 57,942,698 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0458,402,150 - 58,445,909 (-)NCBIUU_Cfam_GSD_1.0
G3bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213112,467,088 - 112,499,763 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651510,916,442 - 10,949,085 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651510,916,442 - 10,949,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G3BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1671,236,339 - 71,276,078 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11671,236,025 - 71,276,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21677,426,673 - 77,442,846 (-)NCBISscrofa10.2Sscrofa10.2susScr3
G3BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12354,335,996 - 54,369,956 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2354,336,113 - 54,368,674 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603423,329,228 - 23,368,946 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
G3bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473337,253,054 - 37,274,067 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473337,246,989 - 37,279,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in G3bp1
1129 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2265
Count of miRNA genes:836
Interacting mature miRNAs:1119
Transcripts:ENSMUST00000018727, ENSMUST00000151790
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse

Markers in Region
C87777  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381155,504,614 - 55,504,760UniSTSGRCm38
MGSCv371155,318,116 - 55,318,262UniSTSGRCm37
Celera1160,290,617 - 60,290,763UniSTS
Cytogenetic Map11B1.3UniSTS
Whitehead/MRC_RH11742.3UniSTS
G3bp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381537,171,439 - 37,172,394UniSTSGRCm38
GRCm38897,428,118 - 97,429,100UniSTSGRCm38
MGSCv371537,101,194 - 37,102,149UniSTSGRCm37
MGSCv37899,952,018 - 99,953,000UniSTSGRCm37
Celera1537,791,305 - 37,792,260UniSTS
Celera8101,724,079 - 101,725,061UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map8D1UniSTS
cM Map11 UniSTS
RH137330  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381155,504,655 - 55,504,836UniSTSGRCm38
MGSCv371155,318,157 - 55,318,338UniSTSGRCm37
Celera1160,290,658 - 60,290,839UniSTS
Cytogenetic Map11B1.3UniSTS
G3bp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381537,170,941 - 37,171,479UniSTSGRCm38
GRCm38897,427,617 - 97,428,158UniSTSGRCm38
MGSCv371537,100,696 - 37,101,234UniSTSGRCm37
MGSCv37899,951,517 - 99,952,058UniSTSGRCm37
Celera1537,790,807 - 37,791,345UniSTS
Celera8101,723,578 - 101,724,119UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map8D1UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map11 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001417583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB001927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000018727   ⟹   ENSMUSP00000018727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1155,360,511 - 55,395,664 (+)Ensembl
GRCm38.p6 Ensembl1155,469,685 - 55,504,838 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151790
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1155,360,544 - 55,378,338 (+)Ensembl
GRCm38.p6 Ensembl1155,469,718 - 55,487,512 (+)Ensembl
RefSeq Acc Id: NM_001417583   ⟹   NP_001404512
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391155,360,521 - 55,391,722 (+)NCBI
RefSeq Acc Id: NM_001417584   ⟹   NP_001404513
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391155,360,521 - 55,391,722 (+)NCBI
RefSeq Acc Id: NM_001417585   ⟹   NP_001404514
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391155,360,521 - 55,391,722 (+)NCBI
RefSeq Acc Id: NM_001417587   ⟹   NP_001404516
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391155,360,521 - 55,391,722 (+)NCBI
RefSeq Acc Id: NM_013716   ⟹   NP_038744
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391155,360,521 - 55,391,722 (+)NCBI
GRCm381155,469,752 - 55,500,887 (+)NCBI
MGSCv371155,283,254 - 55,314,389 (+)RGD
Celera1160,271,641 - 60,286,911 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_038744   ⟸   NM_013716
- Peptide Label: isoform 1
- UniProtKB: P97855 (UniProtKB/Swiss-Prot),   Q571F9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000018727   ⟸   ENSMUST00000018727
RefSeq Acc Id: NP_001404516   ⟸   NM_001417587
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001404513   ⟸   NM_001417584
- Peptide Label: isoform 3
- UniProtKB: Q3UR88 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001404514   ⟸   NM_001417585
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001404512   ⟸   NM_001417583
- Peptide Label: isoform 2
Protein Domains
NTF2   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97855-F1-model_v2 AlphaFold P97855 1-465 view protein structure

Promoters
RGD ID:6820922
Promoter ID:MM_KWN:7492
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000071288,   OTTMUST00000012673,   OTTMUST00000012674,   UC007IZK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361155,282,546 - 55,283,337 (+)MPROMDB
RGD ID:6820328
Promoter ID:MM_KWN:7494
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   Brain,   Kidney,   Lung,   MEF_B6
Transcripts:UC007IZM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361155,314,961 - 55,318,652 (+)MPROMDB
RGD ID:8674704
Promoter ID:EPDNEW_M15383
Type:initiation region
Name:G3bp1_1
Description:Mus musculus GTPase activating protein binding protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15384  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381155,469,734 - 55,469,794EPDNEW
RGD ID:8674706
Promoter ID:EPDNEW_M15384
Type:single initiation site
Name:G3bp1_2
Description:Mus musculus GTPase activating protein binding protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15383  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381155,474,436 - 55,474,496EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1351465 AgrOrtholog
Ensembl Genes ENSMUSG00000018583 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000018727 ENTREZGENE
  ENSMUST00000018727.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.450.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G3BP1_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_transport_factor_2_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ras_GTPase_bind_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:27041 UniProtKB/Swiss-Prot
MGD MGI:1351465 ENTREZGENE
NCBI Gene 27041 ENTREZGENE
PANTHER PTHR10693 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10693:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NTF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen G3bp1 PhenoGen
PROSITE NTF2_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3BP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UR88 ENTREZGENE, UniProtKB/TrEMBL
  Q571F9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 G3bp1  G3BP stress granule assembly factor 1  G3bp1  GTPase activating protein (SH3 domain) binding protein 1  Symbol and/or name change 5135510 APPROVED
2013-02-12 G3bp1  GTPase activating protein (SH3 domain) binding protein 1    Ras-GTPase-activating protein SH3-domain binding protein 1  Symbol and/or name change 5135510 APPROVED