Dstyk (dual serine/threonine and tyrosine protein kinase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Dstyk (dual serine/threonine and tyrosine protein kinase) Mus musculus
Analyze
Symbol: Dstyk
Name: dual serine/threonine and tyrosine protein kinase
RGD ID: 1551598
MGI Page MGI
Description: Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in cellular response to fibroblast growth factor stimulus; negative regulation of apoptotic process; and positive regulation of signal transduction. Predicted to act upstream of or within phosphorylation. Located in apical plasma membrane; basolateral plasma membrane; and cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and skin. Human ortholog(s) of this gene implicated in CAKUT1 and hereditary spastic paraplegia 23. Orthologous to human DSTYK (dual serine/threonine and tyrosine protein kinase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A930019K20Rik; C430014H23Rik; C820013G01; dusty PK; dusty protein kinase; receptor interacting protein kinase 5; receptor-interacting serine/threonine-protein kinase 5; Ripk5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,345,127 - 132,394,697 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,345,293 - 132,394,696 (+)EnsemblGRCm39 Ensembl
GRCm381132,417,389 - 132,466,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,417,555 - 132,466,958 (+)EnsemblGRCm38mm10GRCm38
MGSCv371134,314,030 - 134,363,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361134,245,114 - 134,294,504 (+)NCBIMGSCv36mm8
Celera1135,024,440 - 135,073,889 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. RIP5 is a RIP-homologous inducer of cell death. Zha J, etal., Biochem Biophys Res Commun 2004 Jun 25;319(2):298-303.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15368895   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17123648  
PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23862974   PMID:25400726   PMID:32325033   PMID:35216141  


Genomics

Comparative Map Data
Dstyk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,345,127 - 132,394,697 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,345,293 - 132,394,696 (+)EnsemblGRCm39 Ensembl
GRCm381132,417,389 - 132,466,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,417,555 - 132,466,958 (+)EnsemblGRCm38mm10GRCm38
MGSCv371134,314,030 - 134,363,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361134,245,114 - 134,294,504 (+)NCBIMGSCv36mm8
Celera1135,024,440 - 135,073,889 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.24NCBI
DSTYK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381205,142,505 - 205,211,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1205,142,505 - 205,211,702 (-)EnsemblGRCh38hg38GRCh38
GRCh371205,111,633 - 205,180,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361203,378,256 - 203,447,313 (-)NCBINCBI36Build 36hg18NCBI36
Celera1178,246,858 - 178,315,803 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1176,276,947 - 176,346,439 (-)NCBIHuRef
CHM1_11206,534,987 - 206,604,027 (-)NCBICHM1_1
T2T-CHM13v2.01204,406,864 - 204,475,975 (-)NCBIT2T-CHM13v2.0
Dstyk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81346,409,412 - 46,457,426 (+)NCBIGRCr8
mRatBN7.21343,857,266 - 43,905,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,857,266 - 43,905,269 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1346,464,262 - 46,512,270 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,752,400 - 47,800,402 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01345,013,095 - 45,061,112 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01349,195,325 - 49,243,327 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1349,195,325 - 49,243,316 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01354,263,966 - 54,318,738 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41345,309,935 - 45,357,932 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11345,323,977 - 45,371,970 (+)NCBI
Celera1344,191,910 - 44,239,861 (+)NCBICelera
Cytogenetic Map13q13NCBI
Dstyk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540640,922,972 - 40,971,582 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540640,922,972 - 40,971,433 (-)NCBIChiLan1.0ChiLan1.0
DSTYK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2144,155,916 - 44,227,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1144,121,218 - 44,193,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,750,987 - 180,820,096 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11185,036,950 - 185,107,039 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1185,041,994 - 185,107,041 (-)Ensemblpanpan1.1panPan2
DSTYK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1381,669,721 - 1,716,407 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl381,669,726 - 1,716,254 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha381,763,642 - 1,810,363 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0381,666,218 - 1,712,910 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl381,666,223 - 1,712,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1381,662,282 - 1,708,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0382,053,438 - 2,100,433 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0382,253,623 - 2,300,336 (-)NCBIUU_Cfam_GSD_1.0
Dstyk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934469,951,108 - 70,003,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365577,191,082 - 7,239,816 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365577,191,377 - 7,243,489 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSTYK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl965,833,054 - 65,891,999 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1965,833,050 - 65,892,024 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2972,057,975 - 72,117,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSTYK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12524,128,889 - 24,200,115 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2524,128,899 - 24,195,085 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605524,885,185 - 24,955,720 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dstyk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248075,942,799 - 5,993,049 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248075,942,610 - 5,993,049 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dstyk
1421 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1047
Count of miRNA genes:618
Interacting mature miRNAs:742
Transcripts:ENSMUST00000045110
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
13524520Bodwtq1_mbody wweight QTL 1 (mouse)1131191160135621161Mouse
13513913Heal51_mwound healing/ regeneration 51 (mouse)1131780648135499606Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_172516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_387156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY208852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB749395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ110290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000045110   ⟹   ENSMUSP00000035358
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,345,293 - 132,394,696 (+)Ensembl
GRCm38.p6 Ensembl1132,417,555 - 132,466,958 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187092   ⟹   ENSMUSP00000140376
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,377,136 - 132,379,345 (+)Ensembl
GRCm38.p6 Ensembl1132,449,398 - 132,451,607 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,382,313 - 132,385,377 (+)Ensembl
GRCm38.p6 Ensembl1132,454,575 - 132,457,639 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188389   ⟹   ENSMUSP00000139652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,345,342 - 132,391,830 (+)Ensembl
GRCm38.p6 Ensembl1132,417,604 - 132,464,092 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188973
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,346,115 - 132,361,886 (+)Ensembl
GRCm38.p6 Ensembl1132,418,377 - 132,434,148 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,390,147 - 132,391,094 (+)Ensembl
GRCm38.p6 Ensembl1132,462,409 - 132,463,356 (+)Ensembl
RefSeq Acc Id: NM_172516   ⟹   NP_766104
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,345,191 - 132,394,697 (+)NCBI
GRCm381132,417,453 - 132,466,959 (+)NCBI
MGSCv371134,314,030 - 134,363,536 (+)RGD
Celera1135,024,440 - 135,073,889 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036163420   ⟹   XP_036019313
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,345,288 - 132,394,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163421   ⟹   XP_036019314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,345,628 - 132,394,461 (+)NCBI
Sequence:
RefSeq Acc Id: XR_387156
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,345,127 - 132,380,915 (+)NCBI
GRCm381132,417,389 - 132,453,177 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766104   ⟸   NM_172516
- UniProtKB: Q8C923 (UniProtKB/Swiss-Prot),   Q8C7D4 (UniProtKB/Swiss-Prot),   Q5EBN5 (UniProtKB/Swiss-Prot),   Q3ULK4 (UniProtKB/Swiss-Prot),   Q9CTP7 (UniProtKB/Swiss-Prot),   Q6XUX1 (UniProtKB/Swiss-Prot),   A0A087WP69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035358   ⟸   ENSMUST00000045110
RefSeq Acc Id: ENSMUSP00000139652   ⟸   ENSMUST00000188389
RefSeq Acc Id: ENSMUSP00000140376   ⟸   ENSMUST00000187092
RefSeq Acc Id: XP_036019313   ⟸   XM_036163420
- Peptide Label: isoform X1
- UniProtKB: A0A087WP69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036019314   ⟸   XM_036163421
- Peptide Label: isoform X1
- UniProtKB: A0A087WP69 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6XUX1-F1-model_v2 AlphaFold Q6XUX1 1-927 view protein structure

Promoters
RGD ID:6874940
Promoter ID:EPDNEW_M912
Type:initiation region
Name:Dstyk_2
Description:Mus musculus dual serine/threonine and tyrosine protein kinase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M913  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381132,417,447 - 132,417,507EPDNEW
RGD ID:6874924
Promoter ID:EPDNEW_M913
Type:initiation region
Name:Dstyk_1
Description:Mus musculus dual serine/threonine and tyrosine protein kinase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M912  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381132,417,581 - 132,417,641EPDNEW
RGD ID:6817617
Promoter ID:MM_KWN:2077
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_172516
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361134,313,846 - 134,314,432 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925064 AgrOrtholog
Ensembl Genes ENSMUSG00000042046 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045110 ENTREZGENE
  ENSMUST00000045110.14 UniProtKB/Swiss-Prot
  ENSMUST00000187092.2 UniProtKB/TrEMBL
  ENSMUST00000188389.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:213452 UniProtKB/Swiss-Prot
MGD MGI:1925064 ENTREZGENE
NCBI Gene 213452 ENTREZGENE
PANTHER DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE UniProtKB/Swiss-Prot
  DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE UniProtKB/Swiss-Prot
  DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE UniProtKB/TrEMBL
  DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dstyk PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WP69 ENTREZGENE, UniProtKB/TrEMBL
  A0A087WQX0_MOUSE UniProtKB/TrEMBL
  A1L3P8_MOUSE UniProtKB/TrEMBL
  DUSTY_MOUSE UniProtKB/Swiss-Prot
  Q3ULK4 ENTREZGENE
  Q5EBN5 ENTREZGENE
  Q6A064_MOUSE UniProtKB/TrEMBL
  Q6XUX1 ENTREZGENE
  Q8C7D4 ENTREZGENE
  Q8C923 ENTREZGENE
  Q9CTP7 ENTREZGENE
UniProt Secondary Q3ULK4 UniProtKB/Swiss-Prot
  Q5EBN5 UniProtKB/Swiss-Prot
  Q8C7D4 UniProtKB/Swiss-Prot
  Q8C923 UniProtKB/Swiss-Prot
  Q9CTP7 UniProtKB/Swiss-Prot