Ghrl (ghrelin) - Rat Genome Database

Name: Ghrl
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ghrl (ghrelin) Mus musculus

Analyze

Symbol:

Ghrl

Name:

ghrelin

RGD ID:

732655

MGI Page

MGI

Description:

Predicted to enable ghrelin receptor binding activity; growth hormone-releasing hormone activity; and protein tyrosine kinase activator activity. Involved in adult feeding behavior; positive regulation of appetite; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including excitatory postsynaptic potential; negative regulation of insulin secretion; and positive regulation of synapse assembly. Located in cytoplasm and extracellular region. Is expressed in several structures, including alimentary system; ear; genitourinary system; nervous system; and skeleton. Human ortholog(s) of this gene implicated in diabetic neuropathy; esophagus adenocarcinoma; morbid obesity; obesity; and type 2 diabetes mellitus. Orthologous to human GHRL (ghrelin and obestatin prepropeptide).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

2210006E23Rik; appetite-regulating hormone; Gh; Ghr; growth hormone secretagogue; growth hormone-releasing peptide; m46; motilin-related peptide; MT; MTLRP; MTLRPAP; preproghrelin; proghrelin; uncharacterized protein LOC58991

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	113,693,080 - 113,696,872 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	113,693,080 - 113,696,841 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	113,716,119 - 113,719,911 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	113,716,119 - 113,719,880 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	113,666,113 - 113,669,874 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	113,681,896 - 113,685,657 (-)	NCBI		MGSCv36	mm8
Celera	6	115,541,628 - 115,545,391 (-)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	52.84	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (IDA)

adenocarcinoma (ISO)

Anorexia (ISO)

Atrioventricular Septal Defect 2 (ISO)

bone resorption disease (ISO)

Bulimia (ISO)

Cachexia (ISO)

Cardiac Fibrosis (ISO)

cardiovascular system disease (ISO)

Cocaine-Related Disorders (ISO)

colitis (ISO)

congestive heart failure (ISO)

depressive disorder (ISO)

Diabetes Complications (ISO)

diabetic neuropathy (ISO)

Dwarfism (ISO)

end stage renal disease (ISO)

Esophageal Neoplasms (ISO)

esophagus adenocarcinoma (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Diabetes Mellitus (IEP,ISO)

Fetal Growth Retardation (ISO)

gastric ulcer (ISO)

genetic disease (ISO)

Metabolic Syndrome (ISO)

middle cerebral artery infarction (ISO)

morbid obesity (ISO)

multiple endocrine neoplasia (ISO)

Myocardial Ischemia (ISO)

myoclonic-atonic epilepsy (ISO)

Nerve Degeneration (ISO)

neural tube defect (ISO)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

obstructive sleep apnea (ISO)

Oxygen-Induced Retinopathy (ISO)

Prader-Willi syndrome (ISO)

Pregnancy in Diabetics (ISO)

Reperfusion Injury (ISO)

Sepsis (ISO)

type 2 diabetes mellitus (ISO)

ulcerative colitis (ISO)

Weight Gain (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-anisomycin (EXP)

2,3,4,7,8-Pentachlorodibenzofuran (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

3,7-dihydropurine-6-thione (ISO)

3-isobutyl-1-methyl-7H-xanthine (EXP)

4,4'-diaminodiphenylmethane (EXP)

6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

arsane (ISO)

arsenic atom (ISO)

atropine (ISO)

benzo[a]pyrene (EXP)

bisphenol A (EXP,ISO)

capsaicin (EXP,ISO)

capsazepine (EXP)

carbon nanotube (EXP)

chloroprene (EXP)

chlorpyrifos (EXP,ISO)

chromium(6+) (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

cysteamine (ISO)

D-glucose (ISO)

dexamethasone (EXP)

dexloxiglumide (ISO)

dextran sulfate (EXP)

dopamine (ISO)

doxorubicin (ISO)

famotidine (ISO)

flavonoids (ISO)

fructose (ISO)

fulvestrant (ISO)

furan (ISO)

glucose (ISO)

histamine (ISO)

homoeriodictyol (ISO)

indometacin (ISO)

isoprenaline (ISO)

lipopolysaccharide (ISO)

malonaldehyde (ISO)

mercaptopurine (ISO)

metformin (EXP)

methylmercury chloride (EXP)

monosodium L-glutamate (ISO)

N-methyl-4-phenylpyridinium (ISO)

olanzapine (EXP)

oleanolic acid (EXP)

orlistat (ISO)

ozone (EXP)

paraquat (ISO)

pentobarbital (ISO)

pirinixic acid (EXP)

prostaglandin E2 (ISO)

prostaglandins E (ISO)

prostaglandins F (ISO)

purine-6-thiol (ISO)

resveratrol (ISO)

rotenone (ISO)

ruthenium red (EXP)

serotonin (ISO)

sodium arsenite (EXP,ISO)

sodium disulfite (ISO)

Sodium oleate (ISO)

streptozocin (ISO)

testosterone (ISO)

titanium dioxide (EXP)

triphenyl phosphate (EXP)

tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate (ISO)

uranium atom (EXP,ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin polymerization or depolymerization (ISO)

adult feeding behavior (IDA)

decidualization (ISO)

dendrite development (IMP,ISO)

energy homeostasis (IDA)

excitatory postsynaptic potential (IMP)

G protein-coupled receptor signaling pathway (ISO)

gastric acid secretion (IBA,ISO)

negative regulation of apoptotic process (ISO)

negative regulation of circadian sleep/wake cycle, REM sleep (ISO)

negative regulation of endothelial cell proliferation (ISO)

negative regulation of inflammatory response (IBA,ISO)

negative regulation of insulin secretion (IMP,ISO)

negative regulation of interleukin-1 beta production (ISO)

negative regulation of interleukin-6 production (ISO)

negative regulation of locomotion (IMP)

negative regulation of tumor necrosis factor production (ISO)

positive regulation of adipose tissue development (ISO)

positive regulation of appetite (IDA,IGI,IMP,ISO)

positive regulation of bone development (ISO)

positive regulation of circadian sleep/wake cycle, non-REM sleep (ISO)

positive regulation of cold-induced thermogenesis (IMP)

positive regulation of corticotropin secretion (ISO)

positive regulation of cortisol secretion (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of eating behavior (ISO)

positive regulation of feeding behavior (ISO)

positive regulation of gastric mucosal blood circulation (ISO)

positive regulation of gastro-intestinal system smooth muscle contraction (ISO)

positive regulation of growth (ISO)

positive regulation of growth hormone secretion (IBA,ISO)

positive regulation of growth rate (ISO)

positive regulation of insulin secretion (ISO)

positive regulation of insulin secretion involved in cellular response to glucose stimulus (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of response to food (ISO)

positive regulation of small intestinal transit (ISO)

positive regulation of small intestine smooth muscle contraction (ISO)

positive regulation of sprouting angiogenesis (ISO)

positive regulation of synapse assembly (IMP,ISO)

positive regulation of vascular endothelial cell proliferation (ISO)

postsynaptic modulation of chemical synaptic transmission (ISO)

regulation of cell population proliferation (ISO)

regulation of gastric motility (ISO)

regulation of postsynapse organization (ISO)

regulation of response to food (IBA,ISO)

regulation of transmission of nerve impulse (ISO)

response to electrical stimulus (ISO)

response to estrogen (ISO)

response to hormone (ISO)

response to nutrient levels (ISO)

synapse assembly (IMP)

visual learning (ISO)

Cellular Component

axon (ISO)

cytoplasm (IDA)

extracellular region (IDA,ISO)

extracellular space (IBA,ISO)

glutamatergic synapse (ISO)

Schaffer collateral - CA1 synapse (ISO)

Molecular Function

G protein-coupled receptor binding (ISO)

ghrelin receptor binding (IBA,ISO)

growth hormone-releasing hormone activity (IBA,ISO)

hormone activity (ISO,TAS)

protein binding (ISO)

protein tyrosine kinase activator activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ghrelin system pathway (TAS)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal adipose tissue amount (IAGP)

abnormal food intake (IAGP)

abnormal glucose homeostasis (IAGP)

abnormal metabolism (IAGP)

abnormal non-rapid eye movement sleep pattern (IAGP)

abnormal sleep behavior (IAGP)

decreased body temperature (IAGP)

decreased circulating glucose level (IAGP)

decreased respiratory quotient (IAGP)

impaired adaptive thermogenesis (IAGP)

improved glucose tolerance (IAGP)

increased circulating insulin level (IAGP)

increased insulin secretion (IAGP)

no abnormal phenotype detected (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Ghrelin and other appetite-regulating hormones in paediatric patients with chronic renal failure during dialysis and following kidney transplantation.	Arbeiter AK, etal., Nephrol Dial Transplant. 2009 Feb;24(2):643-6. doi: 10.1093/ndt/gfn529. Epub 2008 Sep 22.
2.	The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes.	Berthold HK, etal., Clin Chim Acta. 2009 Jan;399(1-2):112-6. Epub 2008 Sep 25.
3.	Maintenance of a normal meal-induced decrease in plasma ghrelin levels in children with Prader-Willi syndrome.	Bizzarri C, etal., Horm Metab Res. 2004 Mar;36(3):164-9.
4.	Low serum acylated ghrelin levels are associated with the development of cardiovascular disease in hemodialysis patients.	Chou CC, etal., Intern Med. 2010;49(19):2057-64. Epub 2010 Oct 1.
5.	Ghrelin restores 'lean-type' hunger and energy expenditure profiles in morbidly obese subjects but has no effect on postgastrectomy subjects.	Huda MS, etal., Int J Obes (Lond). 2009 Mar;33(3):317-25. Epub 2009 Feb 3.
6.	Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4.	Hwang S, etal., Endocr J. 2009;56(4):609-17. Epub 2009 Apr 7.
7.	Ghrelin plasma levels in patients with idiopathic short stature.	Iñiguez G, etal., Horm Res Paediatr. 2011 Feb;75(2):94-100. doi: 10.1159/000317429. Epub 2010 Sep 23.
8.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
9.	Ghrelin: structure and function.	Kojima M and Kangawa K, Physiol Rev. 2005 Apr;85(2):495-522.
10.	Comparison of maternal ghrelin and leptin in healthy mothers and mothers with Type 1 diabetes.	Kos K, etal., Diabet Med. 2008 Dec;25(12):1400-5.
11.	Ghrelin reverses experimental diabetic neuropathy in mice.	Kyoraku I, etal., Biochem Biophys Res Commun. 2009 Nov 20;389(3):405-8. Epub 2009 Sep 3.
12.	Fasting serum total ghrelin level inversely correlates with metabolic syndrome in hemodialysis patients.	Lee CC, etal., Arch Med Res. 2008 Nov;39(8):785-90.
13.	Fasting serum ghrelin level is associated with metabolic syndrome in peritoneal dialysis patients.	Lee CJ, etal., Perit Dial Int. 2008 Jun;28 Suppl 3:S196-200.
14.	Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats.	Li L, etal., Acta Pharmacol Sin. 2006 May;27(5):527-35.
15.	MGDs mouse GO annotations	MGD data from the GO Consortium
16.	MGD IEA	MGD IEA
17.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
18.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
19.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
20.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
22.	Increased plasma ghrelin level in lung cancer cachexia.	Shimizu Y, etal., Clin Cancer Res. 2003 Feb;9(2):774-8.
23.	Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.	Steinle NI, etal., J Clin Endocrinol Metab. 2005 Dec;90(12):6672-7. Epub 2005 Oct 4.
24.	Orexin Plays a Role in Growth Impediment Induced by Obstructive Sleep Breathing in Rats.	Tarasiuk A, etal., Sleep. 2016 Apr 1;39(4):887-97. doi: 10.5665/sleep.5648.
25.	Suppression of experimental autoimmune encephalomyelitis by ghrelin.	Theil MM, etal., J Immunol. 2009 Aug 15;183(4):2859-66. doi: 10.4049/jimmunol.0803362. Epub 2009 Jul 20.
26.	Plasma ghrelin concentrations in different clinical stages of diabetic complications and glycemic control in Japanese diabetics.	Ueno H, etal., Endocr J. 2007 Dec;54(6):895-902. Epub 2007 Nov 16.
27.	Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice.	Verhulst PJ, etal., Gastroenterology. 2008 Oct;135(4):1267-76. Epub 2008 Jun 25.
28.	Ghrelin protects mice against endotoxemia-induced acute kidney injury.	Wang W, etal., Am J Physiol Renal Physiol. 2009 Oct;297(4):F1032-7. doi: 10.1152/ajprenal.00044.2009. Epub 2009 Jul 22.
29.	Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity.	Wiedemann T, etal., Diabetes. 2016 Feb;65(2):406-20. doi: 10.2337/db15-0374. Epub 2015 Oct 28.
30.	Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma.	Wu IC, etal., Neoplasia. 2011 Apr;13(4):386-92. doi: 10.1593/neo.101722.
31.	Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis.	Wu R, etal., Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1296-302. Epub 2004 May 20.
32.	Effects of ghrelin on gastric distention sensitive neurons in the arcuate nucleus of hypothalamus and gastric motility in diabetic rats.	Xu L, etal., Peptides. 2013 Oct;48:137-46. doi: 10.1016/j.peptides.2013.08.010. Epub 2013 Aug 18.
33.	[Relationship between Ghrelin and growth hormone secretagogue receptor expression and catch-up growth in rats with intrauterine growth restriction].	Yang HM, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jul;12(7):563-8.
34.	Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.	Zaniolo K, etal., Invest Ophthalmol Vis Sci. 2011 Jul 23;52(8):5376-86. doi: 10.1167/iovs.10-7152.

Additional References at PubMed

PMID:10349636	PMID:10930375	PMID:11042159	PMID:11076861	PMID:11306336	PMID:11718902	PMID:12039068	PMID:12193546	PMID:12456641	PMID:12477932	PMID:12650860	PMID:12660874
PMID:12746326	PMID:14530511	PMID:14585959	PMID:14681479	PMID:14681847	PMID:14708415	PMID:14970313	PMID:15031110	PMID:15070777	PMID:15082713	PMID:15148384	PMID:15178745
PMID:15284202	PMID:15471959	PMID:15471962	PMID:15548585	PMID:15561944	PMID:15576457	PMID:15591499	PMID:15677766	PMID:15680365	PMID:15701644	PMID:15746259	PMID:15870394
PMID:15944193	PMID:15946750	PMID:16002530	PMID:16015681	PMID:16109802	PMID:16141072	PMID:16141073	PMID:16203827	PMID:16210421	PMID:16322794	PMID:16322795	PMID:16376425
PMID:16399505	PMID:16418280	PMID:16430857	PMID:16476508	PMID:16491079	PMID:16601073	PMID:16602821	PMID:16679295	PMID:16825418	PMID:16825606	PMID:16887115	PMID:16951258
PMID:17050541	PMID:17060947	PMID:17130496	PMID:17134539	PMID:17196193	PMID:17202186	PMID:17202410	PMID:17204551	PMID:17255209	PMID:17290011	PMID:17400205	PMID:17400914
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PMID:17975746	PMID:17988662	PMID:18006636	PMID:18048479	PMID:18058910	PMID:18070755	PMID:18071756	PMID:18173746	PMID:18199433	PMID:18202139	PMID:18267071	PMID:18270302
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PMID:19401456	PMID:19406939	PMID:19426541	PMID:19502415	PMID:19503064	PMID:19506321	PMID:19564604	PMID:19602582	PMID:19633195	PMID:19666521	PMID:19759004	PMID:19793886
PMID:19805515	PMID:19906954	PMID:19939974	PMID:19944124	PMID:19965928	PMID:20003319	PMID:20043902	PMID:20044999	PMID:20063013	PMID:20148032	PMID:20185766	PMID:20206170
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PMID:21029370	PMID:21054685	PMID:21081123	PMID:21124019	PMID:21163280	PMID:21173230	PMID:21220053	PMID:21264794	PMID:21298106	PMID:21325042	PMID:21386086	PMID:21464907
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PMID:32350257	PMID:32357262	PMID:32467243	PMID:32994489	PMID:33042003	PMID:33116243	PMID:33345314	PMID:33647468	PMID:33653874	PMID:33658226	PMID:33811703	PMID:33913930
PMID:34201511	PMID:34289060	PMID:34478806	PMID:34518616	PMID:34721302	PMID:34734521	PMID:35302184	PMID:35385777	PMID:35403437	PMID:35797708	PMID:35833540	PMID:35913117

Genomics

Comparative Map Data

Ghrl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	113,693,080 - 113,696,872 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	113,693,080 - 113,696,841 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	113,716,119 - 113,719,911 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	113,716,119 - 113,719,880 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	113,666,113 - 113,669,874 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	113,681,896 - 113,685,657 (-)	NCBI		MGSCv36	mm8
Celera	6	115,541,628 - 115,545,391 (-)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	52.84	NCBI

GHRL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	10,285,666 - 10,292,947 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	3	10,285,666 - 10,292,947 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	10,327,350 - 10,334,631 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	10,302,434 - 10,307,409 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	10,302,433 - 10,307,409	NCBI
Celera	3	10,263,242 - 10,270,439 (-)	NCBI		Celera
Cytogenetic Map	3	p25.3	NCBI
HuRef	3	10,262,844 - 10,269,999 (-)	NCBI		HuRef
CHM1_1	3	10,277,571 - 10,284,767 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	10,278,965 - 10,286,246 (-)	NCBI		T2T-CHM13v2.0

Ghrl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	146,865,712 - 146,869,621 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	146,865,712 - 146,869,621 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	152,250,366 - 152,254,274 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	4	148,031,237 - 148,035,145 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	4	146,659,480 - 146,663,373 (-)	NCBI	Rnor_WKY
Rnor_6.0	4	145,674,157 - 145,678,066 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	145,674,157 - 145,678,066 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	208,969,963 - 208,976,778 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	149,622,566 - 149,628,111 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	149,867,406 - 149,872,952 (-)	NCBI
Celera	4	135,420,041 - 135,423,946 (-)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Ghrl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955561	1,676,576 - 1,681,812 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955561	1,676,475 - 1,682,205 (-)	NCBI	ChiLan1.0	ChiLan1.0

GHRL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	3	10,286,078 - 10,301,544 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	10,221,829 - 10,229,229 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	10,573,537 - 10,580,723 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	10,573,537 - 10,580,723 (-)	Ensembl	panpan1.1		panPan2

GHRL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	8,092,921 - 8,097,512 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	8,092,957 - 8,097,510 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	8,127,316 - 8,131,869 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	8,122,116 - 8,127,217 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	8,122,662 - 8,127,215 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	7,844,540 - 7,849,093 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	8,190,266 - 8,194,819 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	8,163,907 - 8,168,460 (+)	NCBI		UU_Cfam_GSD_1.0

Ghrl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	15,867,085 - 15,872,024 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936602	3,038,549 - 3,042,506 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936602	3,037,862 - 3,044,863 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GHRL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	66,445,992 - 66,452,917 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	66,442,106 - 66,453,576 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	73,453,082 - 73,480,182 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	13	q31	NCBI

GHRL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	46,326,458 - 46,332,906 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	46,325,913 - 46,330,962 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	120,205,064 - 120,210,786 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ghrl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	5,257,830 - 5,262,473 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	5,257,813 - 5,262,878 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ghrl
117 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	180
Count of miRNA genes:	168
Interacting mature miRNAs:	172
Transcripts:	ENSMUST00000064993
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	3050001	117476961	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45290993	128811995	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46912919	136400690	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48696934	125336963	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48696934	148351498	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48703490	125333748	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52138693	116132228	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73476983	134676963	Mouse
12792979	Fbmd2_m	femoral bone mineral density 2, females only (mouse)					6	75026989	115026943	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78606487	121092347	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83690851	146954059	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84099474	118099474	Mouse
1301744	Hdlq11_m	HDL QTL 11 (mouse)			Not determined		6	87480321	121480516	Mouse
1301262	Gasa3_m	gastritis type A susceptibility locus 3 (mouse)			Not determined		6	88982366	122982564	Mouse
1301244	Ichs_m	immediate cutaneous hypersensitivity QTL (mouse)			Not determined		6	90772571	124772807	Mouse
11353842	Bmiq4_m	body mass index QTL 4 (mouse)					6	92584287	146330736	Mouse
1301292	Cfbw2_m	cystic fibrosis body weight 2 (mouse)			Not determined		6	94981612	128981699	Mouse
11040599	Lmr4b_m	leishmaniasis resistance 4b (mouse)					6	96324286	130324483	Mouse
1300704	Cia3_m	collagen induced arthritis QTL 3 (mouse)			Not determined		6	96324286	130324483	Mouse
4141940	W6q5_m	weight 6 weeks QTL 5 (mouse)			Not determined			96632912	146535124	Mouse
4142416	Egq11_m	early growth QTL 11 (mouse)			Not determined			96632912	146535124	Mouse
1357555	Tesq2_m	testis weight QTL 2 (mouse)			Not determined		6	96632912	146535124	Mouse
10043923	Bhr7_m	bronchial hyperresponsiveness 7 (mouse)			Not determined		6	98219814	132219938	Mouse
1301518	Bbaa5_m	B.burgdorferi-associated arthritis 5 (mouse)			Not determined		6	98483798	145881170	Mouse
1301923	Lith6_m	lithogenic gene 6 (mouse)			Not determined		6	98694477	132694676	Mouse
1301915	Chab3_m	cholesterol absorption 3 (mouse)			Not determined		6	98908709	132916997	Mouse
1302131	Bmd8_m	bone mineral density 8 (mouse)			Not determined		6	99132089	133132228	Mouse
1300887	Pabr1_m	plasma apolipoprotein B (human) regulator 1 (mouse)			Not determined		6	103754405	136400690	Mouse
1301509	Sluc3_m	susceptibility to lung cancer 3 (mouse)			Not determined		6	104480321	127019938	Mouse
1357806	Aaj3_m	anxiety in A/J 3 (mouse)			Not determined		6	104480321	136400690	Mouse
1357793	Pnhdlc1_m	plasma non-HDL cholesterol 1 (mouse)			Not determined		6	105541783	114345810	Mouse
4141699	Ibdq2_m	inflammatory bowel disease QTL 2 (mouse)			Not determined			105982366	120894102	Mouse
10412207	Cypr5_m	cytokine production 5 (mouse)			Not determined		6	110815180	144815323	Mouse
13463481	Mcvq14_m	mean corpuscular volume QTL 14 (mouse)					6	111142448	145142541	Mouse
10043891	Tilss4_m	TNF-induced lethal shock susceptibility 3 (mouse)			Not determined		6	112246918	125333748	Mouse
11252138	Clas1_m	carcinogen-induced lung adenoma susceptibility 1 (mouse)					6	112246918	146954059	Mouse

Markers in Region

Ghrl

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	6	E3	UniSTS
cM Map	6	49.7	UniSTS

D6Oda23

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	113,717,974 - 113,718,116	UniSTS	GRCm38
MGSCv37	6	113,667,968 - 113,668,110	UniSTS	GRCm37
Celera	6	115,543,485 - 115,543,627	UniSTS
Cytogenetic Map	6	E3	UniSTS
cM Map	6	49.42	UniSTS

PMC262394P1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	113,716,246 - 113,717,155	UniSTS	GRCm38
MGSCv37	6	113,666,240 - 113,667,149	UniSTS	GRCm37
Celera	6	115,541,755 - 115,542,666	UniSTS
Cytogenetic Map	6	E3	UniSTS
cM Map	6	49.7	UniSTS

PMC262394P3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	113,719,112 - 113,719,385	UniSTS	GRCm38
MGSCv37	6	113,669,106 - 113,669,379	UniSTS	GRCm37
Celera	6	115,544,623 - 115,544,896	UniSTS
Cytogenetic Map	6	E3	UniSTS
cM Map	6	49.7	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001286404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001286405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001286406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001379129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_021488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_138135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB035701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB060078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB111891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC117596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ243503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK008658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK008860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV079302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY179430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC094911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC132230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC132232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY149645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK137452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ993169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ355945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ914266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000064993 ⟹ ENSMUSP00000069567

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,080 - 113,696,841 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,119 - 113,719,880 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203363 ⟹ ENSMUSP00000145366

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,085 - 113,696,419 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,124 - 113,719,458 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203588 ⟹ ENSMUSP00000145514

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,211 - 113,696,390 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,250 - 113,719,429 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203770 ⟹ ENSMUSP00000145281

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,093 - 113,696,809 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,132 - 113,719,848 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204163 ⟹ ENSMUSP00000145096

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,133 - 113,696,408 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,172 - 113,719,447 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204191

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,696,138 - 113,696,415 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,719,177 - 113,719,454 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204533 ⟹ ENSMUSP00000145046

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	113,693,080 - 113,694,653 (-)	Ensembl
GRCm38.p6 Ensembl	6	113,716,119 - 113,717,692 (-)	Ensembl

RefSeq Acc Id:

NM_001286404 ⟹ NP_001273333

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,080 - 113,696,415 (-)	NCBI
GRCm38	6	113,716,119 - 113,719,454 (-)	NCBI
Celera	6	115,541,628 - 115,545,422 (-)	NCBI

Sequence:

show sequence

GTCATCTGTCCTCACCACCAAGACCATGCTGTCTTCAGGCACCATCTGCAGTTTGCTGCTACTC
AGCATGCTCTGGATGGACATGGCCATGGCAGGCTCCAGCTTCCTGAGCCCAGAGCACCAGAAAG
CCCAGAGAAAGGAATCCAAGAAGCCACCAGCTAAACTGCAGCCACGAGCTCTGGAAGGCTGGCT
CCACCCAGAGGACAGAGGACAAGCAGAAGAGACAGAGGAGGAGCTGGAGATCAGGTTCAATGCT
CCCTTCGATGTTGGCATCAAGCTGTCAGGAGCTCAGTATCAGCAGCATGGCCGGGCCCTGGGGA
AGTTTCTTCAGGATATCCTCTGGGAAGAGGTCAAAGAGGCGCCAGCTGACAAGTAACCACGGAC
AGGCCTGACCCCCGTGCTTTCCTTCTCCTGAGCAAGAACTCACATCCGCCTCAGCCTCCTCGGC
AACTCCCAGCACTCTCCTACCACTTTAAGAATAAATGTTCACCTGTATGCCAAATGTTC

hide sequence

RefSeq Acc Id:

NM_001286405 ⟹ NP_001273334

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,080 - 113,696,415 (-)	NCBI
GRCm38	6	113,716,119 - 113,719,454 (-)	NCBI
Celera	6	115,541,628 - 115,545,422 (-)	NCBI

Sequence:

show sequence

GTCATCTGTCCTCACCACCAAGACCATGCTGTCTTCAGGCACCATCTGCAGTTTGCTGCTACTC
AGCATGCTCTGGATGGACATGGCCATGGCAGGCTCCAGCTTCCTGAGCCCAGAGCACCAGAAAG
CCCAGCAGAGAAAGGAATCCAAGAAGCCACCAGCTAAACTGCAGCCACGAGCTCTGGAAGGCTG
GCTCCACCCAGAGGACAGAGGACAAGCAGAAGAGACAGAGGAGGAGCTGGAGATCAGGAGGCGC
CAGCTGACAAGTAACCACGGACAGGCCTGACCCCCGTGCTTTCCTTCTCCTGAGCAAGAACTCA
CATCCGCCTCAGCCTCCTCGGCAACTCCCAGCACTCTCCTACCACTTTAAGAATAAATGTTCAC
CTGTATGCCAAATGTTC

hide sequence

RefSeq Acc Id:

NM_001286406 ⟹ NP_001273335

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,080 - 113,696,415 (-)	NCBI
GRCm38	6	113,716,119 - 113,719,454 (-)	NCBI
Celera	6	115,541,628 - 115,545,422 (-)	NCBI

Sequence:

show sequence

GTCATCTGTCCTCACCACCAAGACCATGCTGTCTTCAGGCACCATCTGCAGTTTGCTGCTACTC
AGCATGCTCTGGATGGACATGGCCATGGCAGGCTCCAGCTTCCTGAGCCCAGAGCACCAGAAAG
CCCAGTTCAATGCTCCCTTCGATGTTGGCATCAAGCTGTCAGGAGCTCAGTATCAGCAGCATGG
CCGGGCCCTGGGGAAGTTTCTTCAGGATATCCTCTGGGAAGAGGTCAAAGAGGCGCCAGCTGAC
AAGTAACCACGGACAGGCCTGACCCCCGTGCTTTCCTTCTCCTGAGCAAGAACTCACATCCGCC
TCAGCCTCCTCGGCAACTCCCAGCACTCTCCTACCACTTTAAGAATAAATGTTCACCTGTATGC
CAAATGTTC

hide sequence

RefSeq Acc Id:

NM_001379129 ⟹ NP_001366058

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,085 - 113,696,426 (-)	NCBI
GRCm38	6	113,716,124 - 113,719,465 (-)	NCBI

Sequence:

show sequence

CTCTCCCCCAGGTCATCTGTCCTCACCACCAAGACCATGCTGTCTTCAGGCACCATCTGCAGTT
TGCTGCTACTCAGCATGCTCTGGATGGACATGGCCATGGCAGGCTCCAGCTTCCTGAGCCCAGA
GCACCAGAAAGCCCAGCAGAGAAAGGAATCCAAGAAGCCACCAGCTAAACTGCAGCCACGAGCT
CTGGAAGGCTGGCTCCACCCAGAGGACAGAGGACAAGCAGAAGAGACAGAGGAGGAGCTGGAGA
TCAGGTTCAATGCTCCCTTCGATGTTGGCATCAAGCTGTCAGGAGCTCAGTATCAGCAGCATGG
CCGGGCCCTGGGGAAGTTTCTTCAGGATATCCTCTGGGAAGAGGTCAAAGAGGCGCCAGCTGAC
AAGTAACCACGGACAGGCCTGACCCCCGTGCTTTCCTTCTCCTGAGCAAGAACTCACATCCGCC
TCAGCCTCCTCGGCAACTCCCAGCACTCTCCTACCACTTTAAGAATAAATGTTCACCTGTATGC
CAAA

hide sequence

RefSeq Acc Id:

NM_021488 ⟹ NP_067463

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,080 - 113,696,872 (-)	NCBI
GRCm38	6	113,716,119 - 113,719,911 (-)	NCBI
MGSCv37	6	113,666,113 - 113,669,874 (-)	RGD
Celera	6	115,541,628 - 115,545,422 (-)	NCBI
cM Map	6		ENTREZGENE

Sequence:

show sequence

ATATAAGGAGAAGCCGGTGAGCAGGCACCACATCCCCAGGCATTCCAGGTCATCTGTCCTCACC
ACCAAGACCATGCTGTCTTCAGGCACCATCTGCAGTTTGCTGCTACTCAGCATGCTCTGGATGG
ACATGGCCATGGCAGGCTCCAGCTTCCTGAGCCCAGAGCACCAGAAAGCCCAGCAGAGAAAGGA
ATCCAAGAAGCCACCAGCTAAACTGCAGCCACGAGCTCTGGAAGGCTGGCTCCACCCAGAGGAC
AGAGGACAAGCAGAAGAGACAGAGGAGGAGCTGGAGATCAGGTTCAATGCTCCCTTCGATGTTG
GCATCAAGCTGTCAGGAGCTCAGTATCAGCAGCATGGCCGGGCCCTGGGGAAGTTTCTTCAGGA
TATCCTCTGGGAAGAGGTCAAAGAGGCGCCAGCTGACAAGTAACCACGGACAGGCCTGACCCCC
GTGCTTTCCTTCTCCTGAGCAAGAACTCACATCCGCCTCAGCCTCCTCGGCAACTCCCAGCACT
CTCCTACCACTTTAAGAATAAATGTTCACCTGTATGCCAAATGTTC

hide sequence

RefSeq Acc Id:

NR_138135

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	113,693,080 - 113,694,653 (-)	NCBI
GRCm38	6	113,716,119 - 113,717,692 (-)	NCBI

Sequence:

show sequence

GATGATCTGACCAGTTTGCCCTGAACAATGGAGTGTGAGAAGAAAAAATTAGCATTTGCTAAGT
TCAATGCTCCCTTCGATGTTGGCATCAAGCTGTCAGGAGCTCAGTATCAGCAGCATGGCCGGGC
CCTGGGGAAGTTTCTTCAGGATATCCTCTGGGAAGAGGTCAAAGAGGCGCCAGCTGACAAGTAA
CCACGGACAGGCCTGACCCCCGTGCTTTCCTTCTCCTGAGCAAGAACTCACATCCGCCTCAGCC
TCCTCGGCAACTCCCAGCACTCTCCTACCACTTTAAGAATAAATGTTCACCTGTATGCCAAATG
TTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001273333	(Get FASTA)	NCBI Sequence Viewer
	NP_001273334	(Get FASTA)	NCBI Sequence Viewer
	NP_001273335	(Get FASTA)	NCBI Sequence Viewer
	NP_001366058	(Get FASTA)	NCBI Sequence Viewer
	NP_067463	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI32231	(Get FASTA)	NCBI Sequence Viewer
	AAI32233	(Get FASTA)	NCBI Sequence Viewer
	AAO27350	(Get FASTA)	NCBI Sequence Viewer
	ACO90203	(Get FASTA)	NCBI Sequence Viewer
	ACO90204	(Get FASTA)	NCBI Sequence Viewer
	ACO90205	(Get FASTA)	NCBI Sequence Viewer
	ACO90206	(Get FASTA)	NCBI Sequence Viewer
	ACO90207	(Get FASTA)	NCBI Sequence Viewer
	ACO90208	(Get FASTA)	NCBI Sequence Viewer
	ACR83863	(Get FASTA)	NCBI Sequence Viewer
	BAB19046	(Get FASTA)	NCBI Sequence Viewer
	BAB25814	(Get FASTA)	NCBI Sequence Viewer
	BAB25934	(Get FASTA)	NCBI Sequence Viewer
	BAB69857	(Get FASTA)	NCBI Sequence Viewer
	BAC77409	(Get FASTA)	NCBI Sequence Viewer
	CAB46500	(Get FASTA)	NCBI Sequence Viewer
	EDK99497	(Get FASTA)	NCBI Sequence Viewer
	EDK99498	(Get FASTA)	NCBI Sequence Viewer
	EDK99499	(Get FASTA)	NCBI Sequence Viewer
	EDK99500	(Get FASTA)	NCBI Sequence Viewer
	Q9EQX0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_067463 ⟸ NM_021488
- Peptide Label:	isoform 1 preproprotein
- UniProtKB:	Q9WUZ1 (UniProtKB/Swiss-Prot), Q9EQX0 (UniProtKB/Swiss-Prot), A2RSS9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQ AEETEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPADK hide sequence

RefSeq Acc Id:	NP_001273335 ⟸ NM_001286406
- Peptide Label:	isoform 4 precursor
- UniProtKB:	Q9EQX0 (UniProtKB/Swiss-Prot), Q7TSD1 (UniProtKB/TrEMBL), A0A8C6I687 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQFNAPFDVGIKLSGAQYQQHGRALGKFLQ DILWEEVKEAPADK hide sequence

RefSeq Acc Id:	NP_001273333 ⟸ NM_001286404
- Peptide Label:	isoform 2 preproprotein
- UniProtKB:	Q9EQX0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQRKESKKPPAKLQPRALEGWLHPEDRGQA EETEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPADK hide sequence

RefSeq Acc Id:	NP_001273334 ⟸ NM_001286405
- Peptide Label:	isoform 3 precursor
- UniProtKB:	Q9EQX0 (UniProtKB/Swiss-Prot), Q811T4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQ AEETEEELEIRRRQLTSNHGQA hide sequence

RefSeq Acc Id:	NP_001366058 ⟸ NM_001379129
- Peptide Label:	isoform 1 preproprotein
- UniProtKB:	Q9WUZ1 (UniProtKB/Swiss-Prot), A2RSS9 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSMUSP00000145096 ⟸ ENSMUST00000204163

RefSeq Acc Id:

ENSMUSP00000145281 ⟸ ENSMUST00000203770

RefSeq Acc Id:

ENSMUSP00000145514 ⟸ ENSMUST00000203588

RefSeq Acc Id:

ENSMUSP00000145366 ⟸ ENSMUST00000203363

RefSeq Acc Id:

ENSMUSP00000145046 ⟸ ENSMUST00000204533

RefSeq Acc Id:

ENSMUSP00000069567 ⟸ ENSMUST00000064993

Protein Domains

Motilin/ghrelin Motilin/ghrelin-associated peptide

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9EQX0-F1-model_v2	AlphaFold	Q9EQX0	1-117	view protein structure

Promoters

RGD ID:

6839342

Promoter ID:

MM_KWN:47209

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Kidney, MEF_B6

Transcripts:

ENSMUST00000080745, ENSMUST00000082099, NM_021488, UC009DHJ.1, UC009DHK.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	113,669,421 - 113,670,622 (-)	MPROMDB

RGD ID:

6890684

Promoter ID:

EPDNEW_M8790

Type:

multiple initiation site

Name:

Ghrl_1

Description:

Mus musculus ghrelin , transcript variant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	113,719,465 - 113,719,525	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1930008	AgrOrtholog
Ensembl Genes	ENSMUSG00000064177	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000069567	ENTREZGENE
	ENSMUSP00000069567.6	UniProtKB/Swiss-Prot
	ENSMUSP00000145046.2	UniProtKB/TrEMBL
	ENSMUSP00000145096	ENTREZGENE
	ENSMUSP00000145096.2	UniProtKB/Swiss-Prot
	ENSMUSP00000145281	ENTREZGENE
	ENSMUSP00000145281.2	UniProtKB/Swiss-Prot
	ENSMUSP00000145366	ENTREZGENE
	ENSMUSP00000145366.2	UniProtKB/TrEMBL
	ENSMUSP00000145514	ENTREZGENE
	ENSMUSP00000145514.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000064993	ENTREZGENE
	ENSMUST00000064993.8	UniProtKB/Swiss-Prot
	ENSMUST00000203363	ENTREZGENE
	ENSMUST00000203363.3	UniProtKB/TrEMBL
	ENSMUST00000203588	ENTREZGENE
	ENSMUST00000203588.2	UniProtKB/TrEMBL
	ENSMUST00000203770	ENTREZGENE
	ENSMUST00000203770.3	UniProtKB/Swiss-Prot
	ENSMUST00000204163	ENTREZGENE
	ENSMUST00000204163.3	UniProtKB/Swiss-Prot
	ENSMUST00000204533	ENTREZGENE
	ENSMUST00000204533.3	UniProtKB/TrEMBL
InterPro	Motilin_assoc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Motilin_ghrelin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Preproghrelin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:58991	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1930008	ENTREZGENE
NCBI Gene	58991	ENTREZGENE
PANTHER	APPETITE-REGULATING HORMONE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR14122	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Motilin_assoc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Motilin_ghrelin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ghrl	PhenoGen
PRINTS	GHRELIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0N4SVC9_MOUSE	UniProtKB/TrEMBL
	A0A8C6I687	ENTREZGENE
	A2RSS9	ENTREZGENE, UniProtKB/TrEMBL
	GHRL_MOUSE	UniProtKB/Swiss-Prot
	Q7TSD1	ENTREZGENE, UniProtKB/TrEMBL
	Q811T4	ENTREZGENE, UniProtKB/TrEMBL
	Q9EQX0	ENTREZGENE
	Q9WUZ1	ENTREZGENE
UniProt Secondary	Q9WUZ1	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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