Reep1 (receptor accessory protein 1) - Rat Genome Database
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Gene: Reep1 (receptor accessory protein 1) Mus musculus
Analyze
Symbol: Reep1
Name: receptor accessory protein 1
RGD ID: 1313135
MGI Page MGI
Description: Is expressed in diaphragm; nervous system; neural retina; and skeletal musculature. Used to study hereditary spastic paraplegia 31. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 5B and hereditary spastic paraplegia 31. Orthologous to human REEP1 (receptor accessory protein 1); INTERACTS WITH 1,2-dimethylhydrazine; 4-hydroxyphenyl retinamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW558420; C87808; D6Ertd253; D6Ertd253e; receptor expression enhancing protein 1; receptor expression-enhancing protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,684,413 - 71,787,694 (+)NCBIGRCm39mm39
GRCm39 Ensembl671,684,545 - 71,787,694 (+)Ensembl
GRCm38671,707,429 - 71,810,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,707,561 - 71,810,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,657,854 - 71,760,696 (+)NCBIGRCm37mm9NCBIm37
MGSCv36671,637,369 - 71,740,211 (+)NCBImm8
Celera673,791,587 - 73,894,394 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15345747   PMID:15489334  
PMID:15550249   PMID:16141072   PMID:16141073   PMID:16602821   PMID:21267068   PMID:21873635   PMID:24051375   PMID:24098485   PMID:24478229   PMID:24668814   PMID:27638887   PMID:32325033  
PMID:33137126  


Genomics

Comparative Map Data
Reep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,684,413 - 71,787,694 (+)NCBIGRCm39mm39
GRCm39 Ensembl671,684,545 - 71,787,694 (+)Ensembl
GRCm38671,707,429 - 71,810,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,707,561 - 71,810,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,657,854 - 71,760,696 (+)NCBIGRCm37mm9NCBIm37
MGSCv36671,637,369 - 71,740,211 (+)NCBImm8
Celera673,791,587 - 73,894,394 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.2NCBI
REEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl286,213,993 - 86,338,083 (-)EnsemblGRCh38hg38GRCh38
GRCh38286,213,993 - 86,338,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37286,441,116 - 86,565,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,294,633 - 86,418,288 (-)NCBINCBI36hg18NCBI36
Build 34286,352,779 - 86,476,435NCBI
Celera286,269,251 - 86,393,245 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef286,338,580 - 86,462,643 (-)NCBIHuRef
CHM1_1286,370,561 - 86,495,314 (-)NCBICHM1_1
Reep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24103,746,004 - 103,862,347 (+)NCBI
Rnor_6.0 Ensembl499,618,622 - 99,735,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0499,618,622 - 99,735,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04164,396,429 - 164,513,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,982,925 - 105,099,852 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14105,227,462 - 105,342,336 (+)NCBI
Celera492,903,130 - 93,018,649 (+)NCBICelera
Cytogenetic Map4q31NCBI
Reep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,369,490 - 1,425,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554241,369,490 - 1,425,611 (+)NCBIChiLan1.0ChiLan1.0
REEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A87,814,041 - 87,881,687 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,814,047 - 87,936,984 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A86,268,147 - 86,391,520 (-)NCBIMhudiblu_PPA_v0panPan3
REEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1738,807,014 - 38,906,196 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11738,807,217 - 38,908,434 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Reep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367121,186,565 - 1,241,829 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl358,435,510 - 58,558,939 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1358,436,319 - 58,558,943 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2361,264,880 - 61,327,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
REEP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11420,819,318 - 20,924,484 (+)NCBI
Reep1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474916,933,575 - 17,042,017 (+)NCBI

Position Markers
AW558420  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38671,810,420 - 71,810,545UniSTSGRCm38
MGSCv37671,760,414 - 71,760,539UniSTSGRCm37
Celera673,894,112 - 73,894,237UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6716.86UniSTS
D6Mit143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38671,782,185 - 71,782,314UniSTSGRCm38
MGSCv37671,732,179 - 71,732,308UniSTSGRCm37
Celera673,865,860 - 73,865,989UniSTS
Cytogenetic Map6C1UniSTS
cM Map630.3UniSTS
Whitehead Genetic619.7UniSTS
Whitehead/MRC_RH6716.76UniSTS
C87808  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38671,810,186 - 71,810,439UniSTSGRCm38
MGSCv37671,760,180 - 71,760,433UniSTSGRCm37
Celera673,893,878 - 73,894,131UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6723.71UniSTS
RH126670  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6718.62UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64160000075600000Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64211637376116515Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64211637376116515Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64211637376116515Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64211637376116515Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64382681377811523Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64382681377811523Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64382681377811523Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64382681377811523Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64382681377811523Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64382681377811523Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4872655675447710Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:994
Count of miRNA genes:565
Interacting mature miRNAs:672
Transcripts:ENSMUST00000121469
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000121469   ⟹   ENSMUSP00000112662
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,707,561 - 71,810,710 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212631   ⟹   ENSMUSP00000148678
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,707,897 - 71,808,310 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212792   ⟹   ENSMUSP00000148341
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,707,870 - 71,810,246 (+)Ensembl
RefSeq Acc Id: NM_178608   ⟹   NP_848723
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39671,684,665 - 71,787,694 (+)NCBI
GRCm38671,707,681 - 71,810,710 (+)ENTREZGENE
MGSCv37671,657,854 - 71,760,696 (+)RGD
Celera673,791,408 - 73,894,402 (+)ENTREZGENE
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030255495   ⟹   XP_030111355
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39671,684,413 - 71,787,694 (+)NCBI
GRCm38671,707,429 - 71,810,710 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004942980
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39671,684,413 - 71,787,694 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_848723   ⟸   NM_178608
- UniProtKB: Q8BGH4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030111355   ⟸   XM_030255495
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000112662   ⟸   ENSMUST00000121469
RefSeq Acc Id: ENSMUSP00000148678   ⟸   ENSMUST00000212631
RefSeq Acc Id: ENSMUSP00000148341   ⟸   ENSMUST00000212792

Promoters
RGD ID:6839841
Promoter ID:MM_KWN:46433
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:ENSMUST00000121469
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36671,657,711 - 71,658,211 (+)MPROMDB
RGD ID:6839840
Promoter ID:MM_KWN:46434
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000064280
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36671,705,971 - 71,706,471 (+)MPROMDB
RGD ID:6889984
Promoter ID:EPDNEW_M8443
Type:initiation region
Name:Reep1_1
Description:Mus musculus receptor accessory protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38671,707,870 - 71,707,930EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1098827 AgrOrtholog
Ensembl Genes ENSMUSG00000052852 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000112662 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148341 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000148678 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000121469 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000212631 UniProtKB/TrEMBL
  ENSMUST00000212792 ENTREZGENE, UniProtKB/TrEMBL
InterPro TB2_DP1_HVA22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:52250 UniProtKB/Swiss-Prot
MGD MGI:1098827 ENTREZGENE
NCBI Gene 52250 ENTREZGENE
PANTHER PTHR12300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TB2_DP1_HVA22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Reep1 PhenoGen
UniProt A0A1D5RLF1_MOUSE UniProtKB/TrEMBL
  A0A1D5RM91_MOUSE UniProtKB/TrEMBL
  Q8BGH4 ENTREZGENE, UniProtKB/Swiss-Prot