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Gene: Tdg (thymine DNA glycosylase) Mus musculus
Symbol: Tdg
Name: thymine DNA glycosylase
Description: Exhibits several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in several processes, including DNA metabolic process; negative regulation of chromatin binding activity; and regulation of gene expression. Localizes to the nucleus. Colocalizes with the PML body. Is expressed in several structures, including epithelium; genitourinary system; nervous system; retina; and skin. Orthologous to human TDG (thymine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; JZA-3; Jza1; thymine-DNA glycosylase
Homo sapiens (human) : TDG (thymine DNA glycosylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tdg (thymine-DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdg (thymine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : TDG (thymine DNA glycosylase)
Canis lupus familiaris (dog) : TDG (thymine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdg (thymine DNA glycosylase)
Sus scrofa (pig) : TDG (thymine DNA glycosylase)
more info ...
Related Pseudogenes: Gm18293   Gm5197   Gm5597   Gm9855  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381082,629,814 - 82,650,799 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371082,092,583 - 82,113,239 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,059,680 - 82,080,598 (+)NCBImm8
Celera1084,612,863 - 84,633,428 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tdg
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617602
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.