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Gene: Tdg (thymine DNA glycosylase) Mus musculus
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Symbol: Tdg
Name: thymine DNA glycosylase
Description: Exhibits several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in several processes, including DNA metabolic process; negative regulation of chromatin binding activity; and regulation of gene expression. Localizes to the nucleus. Colocalizes with the PML body. Is expressed in several structures, including epithelium; genitourinary system; nervous system; retina; and skin. Orthologous to human TDG (thymine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; JZA-3; Jza1; thymine-DNA glycosylase
Orthologs:
Homo sapiens (human) : TDG (thymine DNA glycosylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tdg (thymine-DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdg (thymine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : TDG (thymine DNA glycosylase)
Canis lupus familiaris (dog) : TDG (thymine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdg (thymine DNA glycosylase)
Sus scrofa (pig) : TDG (thymine DNA glycosylase)
more info ...
Related Pseudogenes: Gm18293   Gm5197   Gm5597   Gm9855  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381082,629,814 - 82,650,799 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371082,092,583 - 82,113,239 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,059,680 - 82,080,598 (+)NCBImm8
Celera1084,612,863 - 84,633,428 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tdg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617602
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.