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Gene: Wfdc2 (WAP four-disulfide core domain 2) Mus musculus
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Symbol: Wfdc2
Name: WAP four-disulfide core domain 2
Description: Predicted to have aspartic-type endopeptidase inhibitor activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to localize to the extracellular region. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; liver; and retina. Orthologous to human WFDC2 (WAP four-disulfide core domain 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600023A02Rik; HE4; WAP domain-containing protein HE4; WAP four-disulfide core domain protein 2; WAP5
Orthologs:
Homo sapiens (human) : WFDC2 (WAP four-disulfide core domain 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wfdc2 (WAP four-disulfide core domain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wfdc2 (WAP four-disulfide core domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : WFDC2 (WAP four-disulfide core domain 2)
Canis lupus familiaris (dog) : WFDC2 (WAP four-disulfide core domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wfdc2 (WAP four-disulfide core domain 2)
Sus scrofa (pig) : WFDC2 (WAP four-disulfide core domain 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382164,562,562 - 164,568,510 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372164,388,216 - 164,394,006 (+)NCBIGRCm37mm9NCBIm37
MGSCv362165,511,843 - 165,517,633 (+)NCBImm8
MGSCv362164,253,921 - 164,259,711 (+)NCBImm8
Celera2170,502,300 - 170,504,943 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Wfdc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551892
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.