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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:linalool
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Accession:CHEBI:17580 term browser browse the term
Definition:A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum.
Synonyms:related_synonym: 2,6-dimethylocta-2,7-dien-6-ol;   3,7-Dimethylocta-1,6-dien-3-ol;   Formula=C10H18O;   InChI=1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3;   InChIKey=CDOSHBSSFJOMGT-UHFFFAOYSA-N;   SMILES=CC(C)=CCCC(C)(O)C=C;   beta-linalool;   linalyl alcohol
 alt_id: CHEBI:11712;   CHEBI:1417;   CHEBI:19917
 xref: BPDB:2150;   CAS:78-70-6;   Gmelin:406448;   HMDB:HMDB0036100;   KEGG:C03985;   KNApSAcK:C00003047;   LIPID_MAPS_instance:LMPR0102010004
 xref_mesh: MESH:C018584
 xref: PMID:18695915;   PMID:24570447;   PMID:24758511;   Reaxys:1362385;   VSDB:2150;   Wikipedia:Linalool


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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco1 aconitase 1 increases expression ISO linalool results in increased expression of ACO1 mRNA CTD PMID:24752549 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 increases expression ISO linalool results in increased expression of ACO2 mRNA CTD PMID:24752549 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions
increases expression
ISO PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]
linalool results in increased expression of ACOX1 mRNA; linalool results in increased expression of ACOX1 protein
CTD PMID:24752549 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions
increases expression
ISO PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]
linalool results in increased expression of ACSL1 mRNA; linalool results in increased expression of ACSL1 protein
PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]
CTD PMID:24752549 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO linalool results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions
ISO linalool results in increased expression of AKT1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA
CTD PMID:19922762 PMID:38000518 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP linalool results in decreased expression of ALAS2 mRNA CTD PMID:20536181 NCBI chr  X:22,890,650...22,914,046
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit decreases expression EXP linalool results in decreased expression of APH1B mRNA CTD PMID:20536181 NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO linalool results in increased expression of APOA1 mRNA CTD PMID:24752549 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression ISO linalool results in decreased expression of APOC3 mRNA
linalool results in decreased expression of APOC3 mRNA; linalool results in decreased expression of APOC3 protein
CTD PMID:24752549 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Ar androgen receptor multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atf2 activating transcription factor 2 increases expression ISO linalool results in increased expression of ATF2 mRNA CTD PMID:19922762 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO linalool results in increased expression of BAK1 mRNA CTD PMID:28567457 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO linalool results in increased expression of BAX mRNA CTD PMID:26703569 PMID:28567457 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO linalool results in decreased expression of BCL2 mRNA CTD PMID:28567457 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO linalool results in decreased expression of BCL2L1 mRNA CTD PMID:28567457 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO linalool results in increased expression of BIRC2 mRNA CTD PMID:19922762 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO linalool results in increased expression of BIRC3 mRNA CTD PMID:19922762 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Casp3 caspase 3 increases expression
increases activity
ISO linalool results in increased expression of CASP3 mRNA
linalool results in increased activity of CASP3 protein
CTD PMID:26703569 PMID:28567457 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression ISO linalool results in increased expression of CASP8 mRNA CTD PMID:26703569 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
increases activity
ISO linalool results in increased expression of CASP9 mRNA
linalool results in increased activity of CASP9 protein
CTD PMID:26703569 PMID:28567457 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cat catalase multiple interactions EXP
ISO
linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of CAT protein]; linalool inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA
CTD PMID:30466616 PMID:37729970 PMID:38000518 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Cd86 CD86 molecule increases expression ISO linalool metabolite results in increased expression of CD86 protein CTD PMID:29029310 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh1 cadherin 1 increases expression ISO linalool results in increased expression of CDH1 mRNA CTD PMID:26703569 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO linalool results in increased expression of CDKN1A mRNA CTD PMID:19922762 PMID:26703569 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO linalool results in increased expression of CDKN1B mRNA CTD PMID:19922762 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO linalool results in increased expression of CDKN1C mRNA CTD PMID:19922762 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO linalool results in increased expression of CDKN2A mRNA CTD PMID:26703569 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO linalool results in increased expression of CDKN2B mRNA CTD PMID:19922762 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO linalool results in increased expression of CDKN2C mRNA CTD PMID:26703569 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP linalool results in increased expression of CEBPB mRNA CTD PMID:20536181 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP linalool results in increased expression of CEBPD mRNA CTD PMID:20536181 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression EXP linalool results in increased expression of COL10A1 mRNA CTD PMID:20536181 NCBI chr20:39,737,536...39,744,518
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cp ceruloplasmin multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of CP protein] CTD PMID:37729970 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Csn2 casein beta increases expression ISO linalool results in increased expression of CSN2 mRNA CTD PMID:19922762 NCBI chr14:20,601,824...20,609,061
Ensembl chr14:20,322,581...20,329,817
JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions
ISO linalool results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalool results in increased expression of CTSD mRNA]
CTD PMID:19922762 PMID:31393563 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO linalool results in increased expression of CYP1A1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA
CTD PMID:20491607 PMID:38000518 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO linalool results in increased expression of CYP27A1 mRNA CTD PMID:24752549 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO linalool results in increased expression of DHCR7 mRNA CTD PMID:24752549 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP linalool results in increased expression of DNAJB1 mRNA CTD PMID:20536181 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression ISO linalool results in increased expression of ECHS1 mRNA CTD PMID:24752549 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Edn1 endothelin 1 increases expression ISO linalool results in increased expression of EDN1 mRNA CTD PMID:19922762 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO linalool results in increased expression of EGFR mRNA CTD PMID:19922762 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression ISO linalool results in decreased expression of ELOVL3 mRNA CTD PMID:24752549 NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO linalool results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of F2 protein] CTD PMID:37729970 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO linalool results in increased expression of FABP1 mRNA CTD PMID:24752549 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fn1 fibronectin 1 increases expression ISO linalool results in increased expression of FN1 mRNA CTD PMID:19922762 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP linalool results in increased expression of FOS mRNA CTD PMID:20536181 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression EXP linalool results in increased expression of GABBR1 mRNA CTD PMID:20536181 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO linalool results in increased expression of GADD45A mRNA; linalool results in increased expression of GADD45A protein CTD PMID:19922762 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO linalool results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions
ISO linalool results in increased expression of GREB1 mRNA
Fulvestrant inhibits the reaction [linalool results in increased expression of GREB1 mRNA]
CTD PMID:31393563 NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP linalool results in decreased expression of HBB mRNA CTD PMID:20536181 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression
multiple interactions
ISO linalool results in decreased expression of HMGCR mRNA; linalool results in decreased expression of HMGCR protein
linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter]; linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]; linalool results in decreased expression of and results in increased ubiquitination of HMGCR protein
CTD PMID:21944868 PMID:24613879 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO linalool metabolite results in increased expression of HMOX1 mRNA CTD PMID:29029310 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP linalool results in increased expression of HOMER1 mRNA CTD PMID:20536181 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression ISO linalool results in increased expression of HSF1 mRNA CTD PMID:19922762 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO linalool results in increased expression of HSP90AA1 mRNA CTD PMID:19922762 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression EXP linalool results in increased expression of HSPA1L mRNA CTD PMID:20536181 NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO linalool results in increased expression of HSPA4 mRNA CTD PMID:19922762 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP linalool results in increased expression of HSPB1 mRNA CTD PMID:20536181 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases expression ISO linalool results in increased expression of HSPB2 mRNA CTD PMID:19922762 NCBI chr 8:59,989,640...59,991,215
Ensembl chr 8:51,081,342...51,094,533
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP linalool results in increased expression of HSPH1 mRNA CTD PMID:20536181 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO linalool metabolite results in increased expression of ICAM1 protein
linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
CTD PMID:29029310 PMID:29276222 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO linalool results in increased expression of ID2 mRNA CTD PMID:19922762 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Il10 interleukin 10 multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of IL10 protein] CTD PMID:37729970 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in increased expression of IL1B protein] CTD PMID:37729970 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in increased expression of IL6 protein] CTD PMID:37729970 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO linalool results in increased expression of INSIG1 protein CTD PMID:21944868 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO linalool results in increased expression of INSIG2 mRNA CTD PMID:24752549 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO linalool results in increased expression of JUN protein CTD PMID:19922762 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter] CTD PMID:21944868 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO linalool results in increased expression of LIPA mRNA CTD PMID:24752549 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lpl lipoprotein lipase increases expression
multiple interactions
ISO linalool results in increased expression of LPL mRNA; linalool results in increased expression of LPL protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]
PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]
CTD PMID:24752549 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO linalool metabolite results in increased phosphorylation of MAPK1 protein CTD PMID:29029310 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO linalool metabolite results in increased phosphorylation of MAPK3 protein CTD PMID:29029310 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP linalool results in increased expression of MARCKS mRNA CTD PMID:20536181 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression ISO linalool results in decreased expression of MCEE mRNA CTD PMID:24752549 NCBI chr 1:127,376,311...127,399,551
Ensembl chr 1:117,964,576...117,988,484
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO linalool results in increased expression of MDH mRNA CTD PMID:24752549 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO linalool results in increased expression of MDM2 mRNA CTD PMID:19922762 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO linalool results in increased expression of MMP9 mRNA CTD PMID:26703569 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpz myelin protein zero decreases expression EXP linalool results in decreased expression of MPZ mRNA CTD PMID:20536181 NCBI chr13:86,103,290...86,109,156
Ensembl chr13:83,570,811...83,576,679
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO linalool results in increased expression of MYC mRNA CTD PMID:19922762 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA; linalool metabolite results in increased expression of and results in increased activity of NFE2L2 protein CTD PMID:29029310 PMID:38000518 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
ISO linalool results in increased expression of NFKB1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA
CTD PMID:19922762 PMID:38000518 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Npy neuropeptide Y increases expression ISO
EXP
linalool results in increased expression of NPY protein
linalool results in increased expression of NPY mRNA
CTD PMID:22757684 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO linalool metabolite results in increased expression of NQO1 mRNA CTD PMID:29029310 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO linalool results in increased expression of PCK2 mRNA CTD PMID:24752549 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO linalool results in increased expression of PGM1 mRNA CTD PMID:24752549 NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO linalool results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [linalool results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phf1 PHD finger protein 1 decreases expression ISO linalool results in decreased expression of PHF1 mRNA CTD PMID:27683099 NCBI chr20:5,019,650...5,024,732
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
decreases response to substance
multiple interactions
increases response to substance
ISO linalool results in increased expression of PPARA mRNA; linalool results in increased expression of PPARA protein
PPARA gene mutant form results in decreased susceptibility to linalool
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]
PPARA protein results in increased susceptibility to linalool
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA; linalool binds to and results in increased activity of PPARA protein; PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]; PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
CTD PMID:24752549 PMID:38000518 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 increases expression ISO linalool results in increased expression of PSMD9 mRNA CTD PMID:26703569 NCBI chr12:38,998,027...39,018,340 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 decreases expression EXP linalool results in decreased expression of PXMP4 mRNA CTD PMID:20536181 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
JBrowse link
G Rgs5 regulator of G-protein signaling 5 increases expression EXP linalool results in increased expression of RGS5 mRNA CTD PMID:20536181 NCBI chr13:84,381,077...84,417,875
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA] CTD PMID:30466616 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Rusf1 RUS family member 1 increases expression EXP linalool results in increased expression of RUSF1 mRNA CTD PMID:20536181 NCBI chr 1:182,852,257...182,881,652
Ensembl chr 1:182,852,262...182,880,732
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO linalool results in decreased expression of RUVBL2 mRNA CTD PMID:27683099 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP linalool results in decreased expression of S100A9 mRNA CTD PMID:20536181 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Sele selectin E multiple interactions ISO linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt3 sirtuin 3 decreases expression
multiple interactions
ISO linalool results in decreased expression of SIRT3 mRNA; linalool results in decreased expression of SIRT3 protein
linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]
CTD PMID:28567457 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SLC20A1 mRNA] CTD PMID:30466616 NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc27a4 solute carrier family 27 member 4 increases expression
multiple interactions
ISO linalool results in increased expression of SLC27A4 mRNA; linalool results in increased expression of SLC27A4 protein
PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]
CTD PMID:24752549 NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943
JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression EXP linalool results in decreased expression of SLC6A3 mRNA CTD PMID:20536181 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]; linalool results in decreased activity of and results in increased acetylation of SOD2 protein CTD PMID:28567457 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP linalool results in increased expression of SOX11 mRNA CTD PMID:20536181 NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA] CTD PMID:30466616 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sqle squalene epoxidase increases expression ISO linalool results in increased expression of SQLE mRNA CTD PMID:24752549 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression
multiple interactions
ISO linalool results in decreased expression of SREBF2 mRNA; linalool results in decreased expression of SREBF2 protein
linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]
CTD PMID:21944868 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase decreases expression EXP linalool results in decreased expression of TH mRNA CTD PMID:20536181 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]
linalool inhibits the reaction [Methamphetamine results in increased expression of TNF protein]
CTD PMID:29276222 PMID:37729970 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases response to substance
increases expression
ISO TP53 results in increased susceptibility to linalool
linalool results in increased expression of TP53 mRNA; linalool results in increased expression of TP53 protein
CTD PMID:19922762 PMID:26703569 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO linalool results in increased activity of TRPA1 protein CTD PMID:27735854 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Tshb thyroid stimulating hormone subunit beta decreases expression EXP linalool results in decreased expression of TSHB mRNA CTD PMID:20536181 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO linalool results in increased expression of TXN mRNA CTD PMID:20491607 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression
ISO PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
linalool results in increased expression of UCP2 mRNA; linalool results in increased expression of UCP2 protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]
CTD PMID:24752549 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of linalool CTD PMID:7574722 NCBI chr14:21,122,866...21,138,450
Ensembl chr14:20,768,015...20,783,589
JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vof16 ischemia related factor vof-16 increases expression EXP linalool results in increased expression of VOF16 mRNA CTD PMID:20536181 NCBI chr 8:41,953,062...41,955,169 JBrowse link
G Wnt1 Wnt family member 1 increases expression ISO linalool results in increased expression of WNT1 mRNA CTD PMID:19922762 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 increases expression ISO linalool results in increased expression of WSB1 mRNA CTD PMID:19922762 NCBI chr10:64,700,752...64,717,038
Ensembl chr10:64,202,763...64,219,019
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
(R)-linalyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA CTD PMID:38000518 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ar androgen receptor multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cat catalase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA CTD PMID:38000518 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA CTD PMID:38000518 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions
ISO linalyl acetate results in increased expression of GREB1 mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA]
CTD PMID:31393563 NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:29276222 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA CTD PMID:38000518 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA CTD PMID:38000518 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO linalyl acetate results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA CTD PMID:38000518 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form] CTD PMID:29276222 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Sele selectin E multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selp selectin P multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA] CTD PMID:29276222 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
linalyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA CTD PMID:38000518 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ar androgen receptor multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cat catalase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA CTD PMID:38000518 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA CTD PMID:38000518 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO linalyl acetate results in increased activity of ESR1 protein
NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]
CTD PMID:31393563 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:29276222 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA CTD PMID:38000518 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA CTD PMID:38000518 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO linalyl acetate results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA CTD PMID:38000518 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form] CTD PMID:29276222 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Sele selectin E multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selp selectin P multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA] CTD PMID:29276222 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        antimicrobial agent 18257
          linalool 149
            (R)-linalool 0
            (S)-linalool 0
            3,7-dimethylocta-1,6-dien-3-yl acetate + 42
            linalool hydroperoxide + 0
            linaloyl diphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            organic hydride 18698
                              organic fundamental parent 18698
                                hydrocarbon 18446
                                  terpene 14074
                                    monoterpene 3830
                                      monoterpenoid 2041
                                        linalool 149
                                          (R)-linalool 0
                                          (S)-linalool 0
                                          3,7-dimethylocta-1,6-dien-3-yl acetate + 42
                                          linalool hydroperoxide + 0
                                          linaloyl diphosphate 0
paths to the root