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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nucleoside analogue
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Accession:CHEBI:60783 term browser browse the term
Definition:An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells.
Synonyms:related_synonym: nucleoside analogues


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5-azacytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:22841775 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Azacitidine results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adrb1 adrenoceptor beta 1 affects expression ISO Azacitidine affects the expression of ADRB1 mRNA CTD PMID:19002953 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression
multiple interactions		 ISO Azacitidine affects the expression of ADRB2 mRNA
Azacitidine inhibits the reaction [Particulate Matter results in decreased expression of ADRB2 mRNA]		 CTD PMID:19002953 PMID:30986742 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Afp alpha-fetoprotein increases expression ISO Azacitidine results in increased expression of AFP mRNA CTD PMID:27590069 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 increases expression ISO Azacitidine results in increased expression of AGGF1 mRNA CTD PMID:19194470 NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952 		JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
multiple interactions		 ISO Azacitidine results in increased expression of AHR mRNA
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]		 CTD PMID:12927368 PMID:17682057 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ak5 adenylate kinase 5 increases expression ISO Azacitidine results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22841775 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alad aminolevulinate dehydratase decreases expression ISO Azacitidine results in decreased expression of ALAD mRNA CTD PMID:19194470 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alb albumin decreases expression
increases expression		 ISO Azacitidine results in decreased expression of ALB protein
Azacitidine results in increased expression of ALB mRNA		 CTD PMID:27590069 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]] CTD PMID:17682057 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Andpro androgen regulated protein increases expression ISO Azacitidine results in increased expression of CST4 mRNA CTD PMID:20823114 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966 		JBrowse link
G Anxa1 annexin A1 decreases expression EXP Azacitidine results in decreased expression of ANXA1 protein CTD PMID:17105402 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G App amyloid beta precursor protein decreases methylation
multiple interactions		 ISO Azacitidine results in decreased methylation of APP promoter
Azacitidine results in increased expression of and results in increased cleavage of APP protein; Betaine inhibits the reaction [Azacitidine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [Azacitidine results in increased expression of and results in increased cleavage of APP protein]		 CTD PMID:19635394 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp5 aquaporin 5 decreases methylation
increases expression
multiple interactions		 ISO Azacitidine results in decreased methylation of AQP5 promoter
Azacitidine results in increased expression of AQP5 protein
[Azacitidine results in decreased methylation of AQP5 promoter] which results in increased expression of AQP5 mRNA; Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]		 CTD PMID:17198683 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases expression		 ISO [Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide; HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA] CTD PMID:25953102 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Ar androgen receptor multiple interactions
increases expression		 ISO [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to bicalutamide; [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to Dihydrotestosterone CTD PMID:18324645 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Azacitidine results in increased expression of ARHGAP35 mRNA CTD PMID:20823114 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Azacitidine results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Art1 ADP-ribosyltransferase 1 increases expression ISO Azacitidine results in increased expression of ART1 mRNA CTD PMID:20823114 NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Azacitidine results in increased expression of ASB2 mRNA CTD PMID:20823114 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Azacitidine results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression ISO Azacitidine results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Aurka aurora kinase A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions		 EXP Azacitidine results in increased expression of BAD mRNA
[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA		 CTD PMID:21224363 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression		 EXP [Azacitidine co-treated with entinostat] results in increased expression of BAK1 mRNA
Azacitidine results in increased expression of BAK1 mRNA		 CTD PMID:21224363 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA] CTD PMID:32278510 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Azacitidine results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
Azacitidine results in decreased expression of BCL2 mRNA; Azacitidine results in decreased expression of BCL2 protein		 CTD PMID:32278510 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression		 ISO [metacept-1 co-treated with Azacitidine] results in decreased expression of BCL2L1
[Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein		 CTD PMID:18443271 PMID:19148494 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l13 Bcl2-like 13 increases expression ISO Azacitidine results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
decreases methylation
multiple interactions		 ISO Azacitidine results in increased expression of BDNF mRNA
Azacitidine results in decreased methylation of BDNF promoter
Tetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]; Tetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]		 CTD PMID:18184782 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression EXP Azacitidine results in decreased expression of BGLAP protein CTD PMID:18037191 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Azacitidine results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Bik BCL2-interacting killer multiple interactions
increases expression		 EXP [Azacitidine co-treated with entinostat] results in increased expression of BIK mRNA
Azacitidine results in increased expression of BIK mRNA		 CTD PMID:21224363 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bmp15 bone morphogenetic protein 15 increases expression ISO Azacitidine results in increased expression of BMP15 mRNA CTD PMID:23395740 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Azacitidine results in increased expression of BNIP3 mRNA CTD PMID:25446377 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK multiple interactions
increases expression		 EXP [Azacitidine co-treated with entinostat] results in increased expression of BOK mRNA
Azacitidine results in increased expression of BOK mRNA		 CTD PMID:21224363 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA CTD PMID:18720364 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C17h6orf62 similar to human chromosome 6 open reading frame 62 increases expression ISO Azacitidine results in increased expression of C6ORF62 mRNA CTD PMID:19194470 NCBI chr17:40,256,211...40,267,851
Ensembl chr17:40,256,211...40,276,020 		JBrowse link
G C3ar1 complement C3a receptor 1 increases expression ISO Azacitidine results in increased expression of C3AR1 mRNA CTD PMID:19194470 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G Calca calcitonin-related polypeptide alpha decreases methylation ISO Azacitidine results in decreased methylation of CALCA promoter CTD PMID:19299654 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Azacitidine results in increased expression of CALD1 mRNA CTD PMID:20823114 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 increases expression
multiple interactions		 ISO Azacitidine results in increased expression of CALHM2 mRNA
Cisplatin affects the reaction [Azacitidine results in increased expression of CALHM2 mRNA]		 CTD PMID:36336710 NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218 		JBrowse link
G Casp3 caspase 3 affects expression
increases activity
increases expression
multiple interactions		 ISO Azacitidine affects the expression of CASP3 protein
5-azacytidine co-treated with doxorubicin increases activity of CASP3 protein in lung cancer cells
Azacitidine results in increased expression of CASP3 mRNA
[metacept-1 co-treated with Azacitidine] results in increased expression of CASP3		 CTD
RGD		 PMID:18443271 PMID:19148494 PMID:23395740 PMID:24356455 RGD:153344603 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases expression ISO Azacitidine results in increased expression of CASP8 mRNA CTD PMID:18082045 PMID:23395740 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression ISO Azacitidine results in increased expression of CASP9 mRNA CTD PMID:23395740 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccna1 cyclin A1 multiple interactions
decreases expression		 ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]; Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]; Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter]
Azacitidine results in decreased expression of CCNA1 mRNA		 CTD PMID:17698632 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression		 ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA
Azacitidine results in decreased expression of CCNA2 mRNA		 CTD PMID:18720364 PMID:20823114 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression		 ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA
Azacitidine results in increased expression of CCNB1 protein		 CTD PMID:18720364 PMID:20607034 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Azacitidine results in increased expression of CCND1 mRNA CTD PMID:20823114 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 affects methylation
multiple interactions		 ISO Azacitidine affects the methylation of CCND2 promoter
[Azacitidine affects the methylation of CCND2 promoter] which affects the expression of CCND2 mRNA		 CTD PMID:17016690 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Azacitidine results in decreased expression of CCNG2 mRNA CTD PMID:21245298 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]] CTD PMID:32894642 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA CTD PMID:18720364 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha decreases expression ISO Azacitidine results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732 		JBrowse link
G Cdh1 cadherin 1 decreases methylation
increases expression		 ISO Azacitidine results in decreased methylation of CDH1 promoter
Azacitidine results in increased expression of CDH1 mRNA		 CTD PMID:17520682 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 increases expression EXP Azacitidine results in increased expression of CDH2 mRNA CTD PMID:18037191 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression		 ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA
Azacitidine analog results in increased expression of CDK1 protein		 CTD PMID:18324645 PMID:18720364 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Azacitidine analog results in decreased expression of CDK2 protein CTD PMID:18324645 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Azacitidine analog results in decreased expression of CDK4 protein CTD PMID:18324645 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO
EXP		 Azacitidine analog results in increased expression of CDKN1A protein; Azacitidine results in increased expression of CDKN1A mRNA
[Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A		 CTD PMID:18324645 PMID:19148494 PMID:20823114 PMID:21224363 PMID:25015661 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Azacitidine results in increased expression of CDKN1C mRNA CTD PMID:19194470 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases methylation
affects methylation
increases expression		 EXP
ISO		 [Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene; [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA
Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter]
Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene]
Azacitidine affects the methylation of CDKN2A gene
Azacitidine results in increased expression of CDKN2A mRNA		 CTD PMID:17686055 PMID:18443271 PMID:21224363 PMID:22355787 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases methylation
multiple interactions
affects response to substance		 ISO Azacitidine results in decreased methylation of CDKN2B promoter
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN2B
CDKN2B promoter modified form affects the susceptibility to Azacitidine		 CTD PMID:17611569 PMID:19148494 PMID:19194470 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases methylation
increases expression		 ISO Azacitidine results in decreased methylation of CEBPA promoter
Azacitidine results in increased expression of CEBPA mRNA		 CTD PMID:19194470 PMID:27590069 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cenpa centromere protein A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA CTD PMID:18720364 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpf centromere protein F multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA CTD PMID:18720364 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenpo centromere protein O increases expression ISO Azacitidine results in increased expression of CENPO mRNA CTD PMID:19194470 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314 		JBrowse link
G Chat choline O-acetyltransferase increases expression ISO Azacitidine results in increased expression of CHAT mRNA; Azacitidine results in increased expression of CHAT protein CTD PMID:19151599 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chga chromogranin A decreases expression ISO Azacitidine results in decreased expression of CHGA protein CTD PMID:20607034 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chit1 chitinase 1 increases expression ISO Azacitidine results in increased expression of CHIT1 mRNA CTD PMID:20823114 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 affects expression ISO Azacitidine affects the expression of CHRM1 mRNA CTD PMID:19002953 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects expression ISO Azacitidine affects the expression of CHRM2 mRNA CTD PMID:19002953 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chst14 carbohydrate sulfotransferase 14 increases expression EXP Azacitidine results in increased expression of CHST14 mRNA CTD PMID:27415467 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions
increases expression		 ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]
Azacitidine results in increased expression of CIITA mRNA		 CTD PMID:18829986 PMID:20823114 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Cldn10 claudin 10 decreases expression ISO Azacitidine results in decreased expression of CLDN10 mRNA CTD PMID:19194470 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526 		JBrowse link
G Cldn6 claudin 6 increases expression
decreases methylation
multiple interactions		 ISO Azacitidine results in increased expression of CLDN6 mRNA
Azacitidine results in decreased methylation of CLDN6 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter		 CTD PMID:18661270 NCBI chr10:12,710,302...12,713,987
Ensembl chr10:12,709,960...12,715,973 		JBrowse link
G Cldn7 claudin 7 multiple interactions
decreases expression		 ISO Cisplatin affects the reaction [Azacitidine results in decreased expression of CLDN7 mRNA] CTD PMID:36336710 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171 		JBrowse link
G Cldn8 claudin 8 increases expression ISO Azacitidine results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513 		JBrowse link
G Cldn9 claudin 9 decreases methylation
multiple interactions
increases expression		 ISO Azacitidine results in decreased methylation of CLDN9 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter
Azacitidine results in increased expression of CLDN9 mRNA		 CTD PMID:18661270 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 decreases expression ISO Azacitidine results in decreased expression of CNNM2 mRNA CTD PMID:19194470 NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Azacitidine results in increased expression of COL14A1 mRNA CTD PMID:19194470 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:22841775 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col9a3 collagen type IX alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL9A3 mRNA CTD PMID:18033690 NCBI chr 3:167,711,776...167,734,468
Ensembl chr 3:167,711,840...167,734,465 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Azacitidine results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Cpe carboxypeptidase E increases expression ISO Azacitidine results in increased expression of CPE mRNA CTD PMID:20823114 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cplx1 complexin 1 increases expression ISO Azacitidine results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr14:1,184,677...1,216,392 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter] CTD PMID:19155497 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression EXP Azacitidine results in increased expression of CREB3L4 mRNA CTD PMID:27415467 NCBI chr 2:175,690,340...175,695,846
Ensembl chr 2:175,690,335...175,695,932 		JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO Azacitidine results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Cryaa crystallin, alpha A increases expression EXP Azacitidine results in increased expression of CRYAA protein CTD PMID:17105402 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Cryab crystallin, alpha B increases expression EXP Azacitidine results in increased expression of CRYAB protein CTD PMID:17105402 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP Azacitidine results in increased expression of CSF1 mRNA CTD PMID:17156202 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csn1s1 casein alpha s1 increases expression ISO Azacitidine results in increased expression of CSN1S1 mRNA CTD PMID:20823114 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614 		JBrowse link
G Cst3 cystatin C increases expression ISO Azacitidine results in increased expression of CST3 mRNA CTD PMID:20823114 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases methylation
increases expression		 ISO Azacitidine results in decreased methylation of CXCL12 promoter
Azacitidine results in increased expression of CXCL12 mRNA; Azacitidine results in increased expression of CXCL12 protein		 CTD PMID:19748759 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]
Azacitidine results in increased expression of CYP1A1 mRNA		 CTD PMID:11281733 PMID:12927368 PMID:17682057 PMID:27590069 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
Azacitidine results in increased expression of CYP1A2 mRNA		 CTD PMID:12927368 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression		 ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Azacitidine results in increased expression of CYP1B1 mRNA		 CTD PMID:12927368 PMID:27590069 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Azacitidine results in increased expression of CYP3A4 mRNA CTD PMID:27590069 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Azacitidine results in increased expression of CYTH1 mRNA CTD PMID:19194470 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760 		JBrowse link
G Dapk1 death associated protein kinase 1 affects methylation ISO Azacitidine affects the methylation of DAPK1 promoter CTD PMID:17557868 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dcn decorin multiple interactions
decreases expression		 ISO Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein]
Azacitidine results in decreased expression of DCN mRNA		 CTD PMID:20823114 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Des desmin increases expression
multiple interactions		 EXP
ISO		 Azacitidine results in increased expression of DES mRNA; Azacitidine results in increased expression of DES protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA		 CTD PMID:18037191 PMID:20823114 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO Azacitidine results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO Azacitidine results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases methylation ISO Azacitidine results in decreased methylation of DLK1 promoter CTD PMID:19194470 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dlx5 distal-less homeobox 5 increases expression ISO Azacitidine results in increased expression of DLX5 mRNA CTD PMID:17085970 NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407 		JBrowse link
G Dlx6 distal-less homeobox 6 increases expression ISO Azacitidine results in increased expression of DLX6 mRNA CTD PMID:20823114 NCBI chr 4:34,984,264...34,989,926
Ensembl chr 4:34,984,232...34,991,343 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression		 ISO
EXP		 [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]; Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]
[Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein; [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein		 CTD PMID:19139132 PMID:19723570 PMID:21224363 PMID:28901456 PMID:35066776 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter] CTD PMID:35066776 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter] CTD PMID:35066776 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases methylation
multiple interactions
decreases response to substance		 ISO Azacitidine results in decreased methylation of DPYD promoter
[Azacitidine results in decreased methylation of DPYD promoter] which results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Azacitidine		 CTD PMID:15501990 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Azacitidine results in increased expression of DUSP1 mRNA CTD PMID:20823114 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Azacitidine results in increased expression of DUSP6 mRNA CTD PMID:21245298 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA] CTD PMID:19451745 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO Azacitidine results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Efna3 ephrin A3 increases expression ISO Azacitidine results in increased expression of EFNA3 mRNA CTD PMID:20823114 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Egr2 early growth response 2 increases expression ISO Azacitidine results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Eno2 enolase 2 decreases expression ISO Azacitidine results in decreased expression of ENO2 protein CTD PMID:20607034 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Azacitidine results in increased expression of ENTPD1 mRNA CTD PMID:20823114 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Azacitidine results in increased expression of ESR1 protein CTD PMID:22558281 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Azacitidine results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Azacitidine results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fam8a1 family with sequence similarity 8, member A1 increases expression ISO Azacitidine results in increased expression of FAM8A1 mRNA CTD PMID:19194470 NCBI chr17:18,026,601...18,035,509
Ensembl chr17:18,026,601...18,035,470 		JBrowse link
G Faslg Fas ligand increases response to substance ISO Azacitidine results in increased susceptibility to FASLG protein CTD PMID:18829727 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Azacitidine results in increased expression of FBLN1 mRNA CTD PMID:21245298 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA CTD PMID:18720364 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgf7 fibroblast growth factor 7 decreases expression ISO Azacitidine results in decreased expression of FGF7 mRNA CTD PMID:20823114 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Filip1l filamin A interacting protein 1-like decreases expression ISO Azacitidine results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA CTD PMID:20823114 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein; [Azacitidine results in decreased methylation of FOXP3 gene] which results in increased expression of FOXP3 protein CTD PMID:18493985 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP Azacitidine results in decreased expression of FTL1 protein CTD PMID:17105402 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Azacitidine results in increased expression of FYN mRNA CTD PMID:21245298 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Azacitidine results in increased expression of GABRB1 mRNA CTD PMID:19194470 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases methylation
multiple interactions
increases expression		 ISO Azacitidine results in decreased methylation of GADD45A promoter
[Azacitidine results in increased expression of GADD45A protein] which results in increased susceptibility to docetaxel
Azacitidine results in increased expression of GADD45A mRNA; Azacitidine results in increased expression of GADD45A protein		 CTD PMID:19190346 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B] CTD PMID:18225533 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP Azacitidine results in increased expression of GATA4 mRNA; Azacitidine results in increased expression of GATA4 protein CTD PMID:18037191 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO Azacitidine results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 decreases expression ISO Azacitidine results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Azacitidine results in increased expression of GDF9 mRNA CTD PMID:23395740 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
decreases expression		 EXP
ISO		 Azacitidine results in increased expression of GJA1 protein
Azacitidine results in decreased expression of GJA1 mRNA		 CTD PMID:18037191 PMID:20823114 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation ISO Azacitidine affects the methylation of GNG7 promoter CTD PMID:18219292 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240 		JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO Azacitidine results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384 		JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO Azacitidine results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO 5-azacytidine increases expression of GPX3 mRNA in epithelial cells of stomach RGD PMID:16229808 RGD:151665354 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases methylation ISO Azacitidine results in decreased methylation of GRIN2B gene CTD PMID:18618247 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Guk1 guanylate kinase 1 increases expression ISO Azacitidine results in increased expression of GUK1 mRNA CTD PMID:20823114 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107 		JBrowse link
G Gzmb granzyme B multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein] CTD PMID:19394699 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G H1f0 H1.0 linker histone increases expression ISO Azacitidine results in increased expression of H1-0 protein CTD PMID:16006241 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694 		JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions		 ISO
EXP		 Azacitidine results in increased expression of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]		 CTD PMID:17991895 PMID:25015661 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions ISO Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr10:43,740,702...43,741,262 JBrowse link
G Hgd homogentisate 1, 2-dioxygenase increases expression ISO Azacitidine results in increased expression of HGD mRNA CTD PMID:20823114 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Azacitidine results in increased expression of HGF mRNA CTD PMID:19194470 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hhex hematopoietically expressed homeobox increases expression ISO Azacitidine results in increased expression of HHEX mRNA CTD PMID:27590069 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Azacitidine results in increased expression of HMGA1 mRNA CTD PMID:20823114 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression
multiple interactions		 ISO Azacitidine results in increased expression of HMGA2 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]		 CTD PMID:21245298 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
multiple interactions		 ISO Azacitidine results in decreased expression of HMGB1 mRNA
Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]		 CTD PMID:32278510 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hnf1a HNF1 homeobox A decreases methylation
multiple interactions
increases expression		 ISO Azacitidine results in decreased methylation of HNF1A promoter
HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
Azacitidine results in increased expression of HNF1A mRNA; Azacitidine results in increased expression of HNF1A protein		 CTD PMID:25953102 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Azacitidine results in increased expression of HNF4A mRNA CTD PMID:27590069 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions
increases expression		 ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA]
Azacitidine results in increased expression of HOXA1 mRNA		 CTD PMID:20823114 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases methylation
multiple interactions
increases expression		 ISO Azacitidine results in decreased methylation of HPGD gene
trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA]		 CTD PMID:19584167 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO Azacitidine affects the expression of HSD3B1 mRNA CTD PMID:18033690 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsf1 heat shock transcription factor 1 decreases activity ISO Azacitidine results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Azacitidine results in increased expression of HSPA6 mRNA CTD PMID:19194470 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Azacitidine results in increased expression of ID1 mRNA CTD PMID:19194470 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO Azacitidine results in increased expression of ID3 mRNA CTD PMID:19194470 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]; [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein CTD PMID:18829986 PMID:18945643 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions
increases expression		 ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]
Azacitidine results in increased expression of IGFBP1 mRNA		 CTD PMID:20823114 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Azacitidine results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Il12b interleukin 12B increases expression ISO Azacitidine results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP
ISO		 Azacitidine results in increased expression of IL1B mRNA
Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]		 CTD PMID:17156202 PMID:32894642 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]; Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 affects methylation ISO Azacitidine affects the methylation of IL4 promoter CTD PMID:18158872 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 affects secretion
affects methylation		 ISO Azacitidine affects the secretion of IL6 protein
Azacitidine affects the methylation of IL6 promoter		 CTD PMID:18158872 PMID:18443271 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor affects expression
multiple interactions		 ISO [Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein; Azacitidine affects the expression of IL6R mRNA
[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein		 CTD PMID:18443271 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 increases expression ISO Azacitidine results in increased expression of ISCA1 mRNA CTD PMID:19194470 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Azacitidine results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression ISO Azacitidine results in decreased expression of ITGB2 mRNA CTD PMID:19194470 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itprid2 ITPR interacting domain containing 2 increases expression ISO Azacitidine results in increased expression of ITPRID2 mRNA CTD PMID:20823114 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978 		JBrowse link
G Kdr kinase insert domain receptor increases expression EXP Azacitidine results in increased expression of KDR mRNA CTD PMID:18037191 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA CTD PMID:18720364 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 increases expression
decreases methylation		 ISO Azacitidine results in increased expression of KIR3DL1 mRNA; Azacitidine results in increased expression of KIR3DL1 protein
Azacitidine results in decreased methylation of KIR3DL1 promoter		 CTD PMID:18945643 PMID:19394699 NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050 		JBrowse link
G Klf6 KLF transcription factor 6 increases expression
multiple interactions		 ISO Azacitidine results in increased expression of KLF6 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]		 CTD PMID:21245298 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression ISO Azacitidine analog results in increased expression of KLK3 protein CTD PMID:18324645 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Krt19 keratin 19 increases expression ISO Azacitidine results in increased expression of KRT19 mRNA CTD PMID:20823114 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt32 keratin 32 increases expression ISO Azacitidine results in increased expression of KRT32 mRNA CTD PMID:20823114 NCBI chr10:85,013,551...85,020,578
Ensembl chr10:85,013,554...85,020,534 		JBrowse link
G Krt8 keratin 8 multiple interactions
increases expression		 ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]
Azacitidine results in increased expression of KRT8 mRNA		 CTD PMID:20823114 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lama1 laminin subunit alpha 1 affects localization ISO Azacitidine affects the localization of LAMA1 protein CTD PMID:18033690 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lamb2 laminin subunit beta 2 increases expression ISO Azacitidine results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
G Ldhb lactate dehydrogenase B increases expression ISO Azacitidine results in increased expression of LDHB mRNA CTD PMID:23437403 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 increases expression ISO Azacitidine results in increased expression of LIMS1 mRNA CTD PMID:19194470 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression ISO Azacitidine results in decreased expression of LITAF mRNA CTD PMID:19194470 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Ltb4r leukotriene B4 receptor decreases expression ISO Azacitidine results in decreased expression of LTB4R mRNA CTD PMID:20823114 NCBI chr15:29,263,199...29,265,716 JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Azacitidine results in increased expression of LYZ mRNA CTD PMID:19194470 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Azacitidine results in decreased expression of MAD1L1 mRNA CTD PMID:19194470 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mafb MAF bZIP transcription factor B increases expression
multiple interactions		 ISO Azacitidine results in increased expression of MAFB mRNA
Cisplatin affects the reaction [Azacitidine results in increased expression of MAFB mRNA]		 CTD PMID:36336710 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Azacitidine results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO Azacitidine results in decreased expression of MAP2K5 mRNA CTD PMID:20823114 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO 5-azacytidine decreases expression of MCL1 protein in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA CTD PMID:18720364 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases expression ISO Azacitidine results in increased expression of MDC1 mRNA CTD PMID:20823114 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Azacitidine results in increased expression of MDM2 mRNA CTD PMID:20823114 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mecp2 methyl CpG binding protein 2 multiple interactions ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mef2a myocyte enhancer factor 2a increases expression
affects expression		 ISO Azacitidine results in increased expression of MEF2A
Azacitidine affects the expression of MEF2A protein		 CTD PMID:12094073 PMID:19002953 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Mef2d myocyte enhancer factor 2D affects expression
increases expression		 ISO Azacitidine affects the expression of MEF2D protein
Azacitidine results in increased expression of MEF2D		 CTD PMID:12094073 PMID:19002953 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Megf6 multiple EGF-like-domains 6 decreases expression ISO Azacitidine results in decreased expression of MEGF6 mRNA CTD PMID:19194470 NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139 		JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression EXP Azacitidine results in decreased expression of MESD protein CTD PMID:17105402 NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999 		JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO Azacitidine results in decreased expression of MFAP2 mRNA CTD PMID:20823114 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression ISO Azacitidine affects the expression of MFGE8 mRNA CTD PMID:18033690 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
decreases methylation		 ISO Azacitidine results in increased expression of MGMT mRNA
Azacitidine results in decreased methylation of MGMT protein		 CTD PMID:7511991 PMID:12807730 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mir193a microRNA 193a increases expression ISO 5-azacytidine increases expression of MIR193A in liver cells
5-azacytidine increases expression of MIR193a RNA in lung cancer cells		 RGD PMID:28036298 PMID:24356455 RGD:153344564, RGD:153344603 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir23b microRNA 23b increases expression ISO 5-azacytidine increases expression of MIR23B miRNA in liver cells RGD PMID:28036298 RGD:153344564 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir497 microRNA 497 increases expression
multiple interactions
decreases methylation		 ISO Azacitidine results in increased expression of MIR497 mRNA
Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter]
Azacitidine results in decreased methylation of MIR497 promoter		 CTD PMID:35066776 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir9-3 microRNA 9-3 increases expression ISO 5-azacytidine increases expression of MIR9-3 in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr 1:133,440,049...133,440,138 JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA CTD PMID:18720364 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Azacitidine results in increased expression of MMP1 mRNA CTD PMID:20823114 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO metacept-1 inhibits the reaction [Azacitidine results in increased expression of MMP9] CTD PMID:19148494 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Morf4l2 mortality factor 4 like 2 decreases expression ISO Azacitidine results in decreased expression of MORF4L2 mRNA CTD PMID:20823114 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728 		JBrowse link
G Mov10l1 Mov10 like RNA helicase 1 increases expression ISO Azacitidine results in increased expression of MOV10L1 mRNA CTD PMID:20823114 NCBI chr 7:120,070,171...120,135,406
Ensembl chr 7:120,070,135...120,134,765 		JBrowse link
G Msrb2 methionine sulfoxide reductase B2 increases expression ISO Azacitidine results in increased expression of MSRB2 mRNA CTD PMID:19194470 NCBI chr17:81,974,378...82,000,044
Ensembl chr17:81,974,196...82,000,043 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Azacitidine results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mtrex Mtr4 exosome RNA helicase increases expression ISO Azacitidine results in increased expression of MTREX mRNA CTD PMID:20823114 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 ISO Azacitidine analog results in decreased expression of MYC mRNA
MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]		 CTD PMID:18045574 PMID:19451745 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myf5 myogenic factor 5 increases expression ISO Azacitidine results in increased expression of MYF5 mRNA CTD PMID:18938140 NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177 		JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Azacitidine results in increased expression of MYH7 mRNA; Azacitidine results in increased expression of MYH7 protein CTD PMID:17105402 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Myl2 myosin light chain 2 increases expression EXP Azacitidine results in increased expression of MYL2 mRNA CTD PMID:17105402 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Myod1 myogenic differentiation 1 increases expression EXP
ISO		 Azacitidine results in increased expression of MYOD1 mRNA CTD PMID:18037191 PMID:18938140 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Myog myogenin increases expression ISO Azacitidine results in increased expression of MYOG mRNA CTD PMID:18938140 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of NCAM1 mRNA CTD PMID:18037191 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Nefl neurofilament light chain increases expression ISO Azacitidine results in increased expression of NEFL mRNA CTD PMID:20823114 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 increases expression ISO Azacitidine results in increased expression of NFATC1 mRNA CTD PMID:20823114 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression
multiple interactions		 ISO Azacitidine results in increased expression of NIBAN1 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]		 CTD PMID:21245298 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729 		JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO Azacitidine results in increased expression of NKX2-5 mRNA CTD PMID:18557828 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nlgn3 neuroligin 3 increases expression ISO Azacitidine results in increased expression of NLGN3 mRNA CTD PMID:20823114 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Azacitidine results in increased expression of NME2 protein CTD PMID:17105402 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nmi N-myc (and STAT) interactor increases expression ISO Azacitidine results in increased expression of NMI mRNA CTD PMID:21245298 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression ISO Azacitidine results in increased expression of NNT mRNA; Azacitidine results in increased expression of NNT protein CTD PMID:36336710 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 decreases expression ISO Azacitidine results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 4:5,891,220...5,910,741
Ensembl chr 4:5,892,909...5,909,709 		JBrowse link
G Nphp1 nephrocystin 1 increases expression ISO Azacitidine results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234 		JBrowse link
G Nppa natriuretic peptide A increases expression ISO Azacitidine results in increased expression of NPPA CTD PMID:15005238 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B increases expression ISO Azacitidine results in increased expression of NPPB CTD PMID:15005238 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]] CTD PMID:17682057 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [metacept-1 co-treated with Azacitidine] results in increased expression of NR4A1 CTD PMID:19148494 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression ISO Azacitidine results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Nrn1 neuritin 1 decreases expression ISO Azacitidine results in decreased expression of NRN1 mRNA CTD PMID:19194470 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896 		JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Azacitidine results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nts neurotensin decreases expression ISO Azacitidine results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA CTD PMID:18720364 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 increases expression ISO Azacitidine results in increased expression of NXT2 mRNA CTD PMID:19194470 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899 		JBrowse link
G Ocln occludin increases expression ISO Azacitidine results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 increases expression ISO Azacitidine results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 9:25,828,865...25,842,424
Ensembl chr 9:25,828,869...25,842,352 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression
decreases methylation		 ISO Azacitidine results in decreased expression of OGG1 protein
Azacitidine results in decreased methylation of OGG1 promoter		 CTD PMID:22064374 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Or8b8 olfactory receptor family 8 subfamily B member 8 increases expression ISO Azacitidine results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr 8:37,693,578...37,694,510
Ensembl chr 8:37,693,499...37,694,547 		JBrowse link
G Oxr1 oxidation resistance 1 increases expression ISO Azacitidine results in increased expression of OXR1 mRNA CTD PMID:20823114 NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666 		JBrowse link
G Oxtr oxytocin receptor decreases expression ISO Azacitidine results in decreased expression of OXTR mRNA CTD PMID:21245298 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP
ISO		 Azacitidine results in increased expression of P4HB protein
Azacitidine results in increased expression of P4HB mRNA		 CTD PMID:17105402 PMID:20823114 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Paep progestagen associated endometrial protein decreases expression ISO Azacitidine results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO Azacitidine results in increased expression of PAK1 mRNA CTD PMID:20823114 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Azacitidine results in decreased expression of PANK3 mRNA CTD PMID:19194470 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO Azacitidine results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]		 CTD PMID:32278510 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax4 paired box 4 increases expression ISO Azacitidine results in increased expression of PAX4 mRNA CTD PMID:18949370 NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408 		JBrowse link
G Pcdh18 protocadherin 18 decreases expression ISO Azacitidine results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883 		JBrowse link
G Pcdha1 protocadherin alpha 1 affects methylation ISO Azacitidine affects the methylation of PCDHA1 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha10 protocadherin alpha 10 affects methylation ISO Azacitidine affects the methylation of PCDHA10 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha11 protocadherin alpha 11 affects methylation ISO Azacitidine affects the methylation of PCDHA11 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha2 protocadherin alpha 2 affects methylation ISO Azacitidine affects the methylation of PCDHA2 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha3 protocadherin alpha 3 affects methylation ISO Azacitidine affects the methylation of PCDHA3 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha4 protocadherin alpha 4 affects methylation ISO Azacitidine affects the methylation of PCDHA4 promoter CTD PMID:18204046 NCBI chr18:28,581,040...28,846,214
Ensembl chr18:28,581,225...28,846,211 		JBrowse link
G Pcdha5 protocadherin alpha 5 affects methylation ISO Azacitidine affects the methylation of PCDHA5 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha6 protocadherin alpha 6 affects methylation ISO Azacitidine affects the methylation of PCDHA6 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha7 protocadherin alpha 7 affects methylation ISO Azacitidine affects the methylation of PCDHA7 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha9 protocadherin alpha 9 affects methylation ISO Azacitidine affects the methylation of PCDHA8 promoter; Azacitidine affects the methylation of PCDHA9 promoter CTD PMID:18204046 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdhb20 protocadherin beta 20 decreases expression ISO Azacitidine results in decreased expression of PCDHB14 mRNA CTD PMID:20823114 NCBI chr18:29,211,878...29,215,272
Ensembl chr18:29,211,883...29,215,258 		JBrowse link
G Pcdhb5 protocadherin beta 5 decreases expression ISO Azacitidine results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr18:29,024,315...29,032,183
Ensembl chr18:29,028,382...29,053,259 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions		 EXP Azacitidine results in decreased expression of PCNA protein
[Cisplatin co-treated with Azacitidine] results in decreased expression of PCNA protein		 CTD PMID:19723570 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Azacitidine results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression
decreases methylation		 ISO Azacitidine results in increased expression of PDK4 protein
Azacitidine results in decreased methylation of PDK4 promoter		 CTD PMID:28003426 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of PECAM1 mRNA CTD PMID:18037191 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pfn1 profilin 1 increases expression ISO Azacitidine results in increased expression of PFN1 mRNA CTD PMID:20823114 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Phactr2 phosphatase and actin regulator 2 increases expression ISO Azacitidine results in increased expression of PHACTR2 mRNA CTD PMID:20823114 NCBI chr 1:7,591,254...7,860,431
Ensembl chr 1:7,597,927...7,860,289 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha decreases expression ISO Azacitidine results in decreased expression of PIP5K1A mRNA CTD PMID:19194470 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO Azacitidine results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297 		JBrowse link
G Pitx3 paired-like homeodomain 3 increases expression EXP Azacitidine results in increased expression of PITX3 mRNA CTD PMID:27415467 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Pja1 praja ring finger ubiquitin ligase 1 increases expression ISO Azacitidine results in increased expression of PJA1 mRNA CTD PMID:19194470 NCBI chr  X:64,580,938...64,585,846
Ensembl chr  X:64,580,849...64,585,833 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel increases expression ISO Azacitidine results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Plcb1 phospholipase C beta 1 decreases methylation
decreases response to substance
increases response to substance
increases expression		 ISO Azacitidine results in decreased methylation of PLCB1 promoter
PLCB1 promoter modified form results in decreased susceptibility to Azacitidine
PLCB1 mRNA results in increased susceptibility to Azacitidine; PLCB1 protein results in increased susceptibility to Azacitidine
Azacitidine results in increased expression of PLCB1 mRNA; Azacitidine results in increased expression of PLCB1 protein		 CTD PMID:19805378 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plpp1 phospholipid phosphatase 1 increases expression ISO Azacitidine results in increased expression of PLPP1 mRNA CTD PMID:19194470 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268 		JBrowse link
G Pls3 plastin 3 decreases expression ISO Azacitidine results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Pml PML nuclear body scaffold increases expression ISO Azacitidine results in increased expression of PML mRNA CTD PMID:19194470 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases methylation
increases expression		 ISO Azacitidine results in decreased methylation of PPARG promoter
Azacitidine results in increased expression of PPARG mRNA		 CTD PMID:19589179 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
increases expression
decreases methylation		 ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter]
Azacitidine results in increased expression of PPP2CA mRNA
Azacitidine results in decreased methylation of PPP2CA promoter		 CTD PMID:19155497 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression EXP Azacitidine results in decreased expression of PRDX4 protein CTD PMID:17105402 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prf1 perforin 1 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Prl prolactin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein CTD PMID:20823114 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prom1 prominin 1 increases expression EXP Azacitidine results in increased expression of PROM1 mRNA CTD PMID:18037191 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527 		JBrowse link
G Prss12 serine protease 12 decreases expression ISO Azacitidine results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126 		JBrowse link
G Psen1 presenilin 1 decreases methylation
multiple interactions		 ISO Azacitidine results in decreased methylation of PSEN1 promoter
Betaine inhibits the reaction [Azacitidine results in decreased methylation of PSEN1 promoter]		 CTD PMID:19635394 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter] CTD PMID:22841775 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Azacitidine results in decreased expression of PTHLH mRNA CTD PMID:20823114 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator increases expression ISO Azacitidine results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Azacitidine results in increased expression of PTPRC mRNA CTD PMID:19194470 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression EXP Azacitidine results in increased expression of PTPRO mRNA CTD PMID:14508512 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771 		JBrowse link
G Rab13 RAB13, member RAS oncogene family decreases methylation ISO Azacitidine results in decreased methylation of RAB13 promoter CTD PMID:19194470 NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression ISO Azacitidine results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
Ensembl chr  X:202,405,759...202,413,868 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression ISO Azacitidine results in increased expression of RACGAP1 mRNA CTD PMID:20823114 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Ranbp2 RAN binding protein 2 increases expression ISO Azacitidine results in increased expression of RANBP2 mRNA CTD PMID:19194470 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481 		JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression ISO Azacitidine results in increased expression of RASA3 mRNA CTD PMID:20823114 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804 		JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Azacitidine results in decreased expression of RCN1 mRNA CTD PMID:20823114 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
decreases expression 		ISO Azacitidine affects the localization of RELA protein
5-azacytidine decreases expression of RELA protein in lung cancer cells		 CTD
RGD		 PMID:18443271 PMID:24356455 RGD:153344603 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ret ret proto-oncogene decreases expression ISO Azacitidine results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA CTD PMID:18720364 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein; Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA] CTD PMID:18047684 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rin1 Ras and Rab interactor 1 increases expression ISO Azacitidine results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 increases expression ISO Azacitidine results in increased expression of RPP21 mRNA CTD PMID:20823114 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Azacitidine results in decreased phosphorylation of RPS6 protein CTD PMID:21245298 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO Azacitidine results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Azacitidine results in increased expression of RRM2B mRNA CTD PMID:19010910 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein CTD PMID:18829986 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 affects methylation ISO Azacitidine affects the methylation of RUNX3 gene CTD PMID:18058463 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G S100a14 S100 calcium binding protein A14 decreases expression ISO Azacitidine results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Azacitidine results in increased expression of S100A9 mRNA CTD PMID:19194470 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sall4 spalt-like transcription factor 4 affects methylation ISO Azacitidine affects the methylation of SALL4 promoter CTD PMID:17546590 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822 		JBrowse link
G Scamp4 secretory carrier membrane protein 4 increases expression ISO Azacitidine results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr 7:9,101,504...9,113,929
Ensembl chr 7:9,101,489...9,113,967 		JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Azacitidine results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Sema3a semaphorin 3A increases expression ISO Azacitidine results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sema6c semaphorin 6C increases expression ISO Azacitidine results in increased expression of SEMA6C mRNA CTD PMID:20823114 NCBI chr 2:182,733,635...182,750,066
Ensembl chr 2:182,737,474...182,746,856 		JBrowse link
G Senp3 SUMO specific peptidase 3 increases expression ISO Azacitidine results in increased expression of SENP3 mRNA CTD PMID:20823114 NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593 		JBrowse link
G Six2 SIX homeobox 2 decreases expression
multiple interactions		 ISO Azacitidine results in decreased expression of SIX2 mRNA
Cisplatin affects the reaction [Azacitidine results in decreased expression of SIX2 mRNA]		 CTD PMID:36336710 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Slbp stem-loop histone mRNA binding protein multiple interactions ISO Azacitidine inhibits the reaction [sodium arsenite results in decreased expression of SLBP mRNA] CTD PMID:25266719 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906 		JBrowse link
G Slc28a1 solute carrier family 28 member 1 increases response to substance
multiple interactions
increases uptake		 ISO SLC28A1 protein results in increased susceptibility to Azacitidine
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Sodium affects the reaction [SLC28A1 protein results in increased uptake of Azacitidine]		 CTD PMID:19139132 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 decreases expression ISO Azacitidine results in decreased expression of SLC29A2 mRNA CTD PMID:19194470 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression		 ISO [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA
Azacitidine results in increased expression of SLC5A5 mRNA		 CTD PMID:16954431 PMID:17164311 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 increases expression ISO Azacitidine results in increased expression of SNU13 mRNA CTD PMID:20823114 NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 affects expression ISO Azacitidine affects the expression of SOCS3 protein CTD PMID:18443271 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sox13 SRY-box transcription factor 13 decreases expression ISO Azacitidine results in decreased expression of SOX13 mRNA CTD PMID:20823114 NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762 		JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression EXP Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox8 SRY-box transcription factor 8 decreases expression ISO Azacitidine results in decreased expression of SOX8 mRNA CTD PMID:18033690 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sox9 SRY-box transcription factor 9 affects expression ISO Azacitidine affects the expression of SOX9 mRNA CTD PMID:18033690 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
decreases expression		 ISO Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter]
Azacitidine results in decreased expression of SP1 mRNA
Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]		 CTD PMID:17198683 PMID:18945643 PMID:20823114 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Azacitidine results in increased expression of SP7 mRNA CTD PMID:17085970 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847 		JBrowse link
G Spag5 sperm associated antigen 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA CTD PMID:18720364 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression ISO Azacitidine results in decreased expression of SRPX mRNA CTD PMID:19194470 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Azacitidine results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965 		JBrowse link
G Ssx2ip SSX family member 2 interacting protein increases expression ISO Azacitidine results in increased expression of SSX2IP mRNA CTD PMID:20823114 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745 		JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 increases expression ISO Azacitidine results in increased expression of ST3GAL6 mRNA CTD PMID:19194470 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 decreases expression ISO Azacitidine results in decreased expression of ST8SIA2 mRNA CTD PMID:20823114 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO Azacitidine results in decreased expression of STC2 mRNA CTD PMID:19194470 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stk38 serine/threonine kinase 38 decreases expression ISO Azacitidine results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198 		JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO Azacitidine results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases expression ISO Azacitidine results in increased expression of SULT1C2 mRNA CTD PMID:19194470 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734 		JBrowse link
G Tat tyrosine aminotransferase increases expression ISO Azacitidine results in increased expression of TAT mRNA CTD PMID:27590069 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 decreases expression ISO Azacitidine results in decreased expression of TBC1D4 mRNA CTD PMID:19194470 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO Azacitidine results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745 		JBrowse link
G Tecpr2 tectonin beta-propeller repeat containing 2 increases expression ISO Azacitidine results in increased expression of TECPR2 mRNA CTD PMID:19194470 NCBI chr 6:129,899,541...130,001,975
Ensembl chr 6:129,899,636...130,001,974 		JBrowse link
G Tek TEK receptor tyrosine kinase increases expression EXP Azacitidine results in increased expression of TEK mRNA CTD PMID:18037191 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
decreases methylation
decreases activity		 ISO Azacitidine analog results in decreased expression of TERT mRNA; Azacitidine results in decreased expression of TERT mRNA
E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]; MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
Azacitidine results in decreased methylation of TERT promoter		 CTD PMID:18045574 PMID:19451745 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 increases expression ISO Azacitidine results in increased expression of TFE3 mRNA CTD PMID:19194470 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein
Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]; Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:18493985 PMID:22841775 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thumpd1 THUMP domain containing 1 increases expression ISO Azacitidine results in increased expression of THUMPD1 mRNA CTD PMID:19194470 NCBI chr 1:174,078,875...174,084,915
Ensembl chr 1:174,078,878...174,084,937 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Azacitidine results in increased expression of TIMP1 mRNA CTD PMID:20823114 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Azacitidine results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 increases expression ISO Azacitidine results in increased expression of TMED3 mRNA CTD PMID:20823114 NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346 		JBrowse link
G Tmpo thymopoietin multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA CTD PMID:18720364 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Tnc tenascin C decreases expression ISO Azacitidine results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance		 EXP
ISO		 Azacitidine results in increased expression of TNF mRNA
Azacitidine results in increased susceptibility to TNF protein		 CTD PMID:17156202 PMID:18829727 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance ISO Azacitidine results in increased susceptibility to TNFSF10 protein CTD PMID:18829727 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Azacitidine results in increased expression of TNNI3 protein CTD PMID:17105402 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression EXP Azacitidine results in increased expression of TNNT2 protein CTD PMID:22496879 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA; [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA CTD PMID:18348204 PMID:18720364 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Azacitidine affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA] CTD PMID:21245298 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tpd52 tumor protein D52 increases expression EXP Azacitidine results in increased expression of TPD52 mRNA CTD PMID:27415467 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622 		JBrowse link
G Tpm2 tropomyosin 2 increases expression ISO Azacitidine results in increased expression of TPM2 mRNA CTD PMID:20823114 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992 		JBrowse link
G Tpo thyroid peroxidase increases expression ISO Azacitidine results in increased expression of TPO mRNA CTD PMID:17679169 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tpsg1 tryptase gamma 1 decreases expression ISO Azacitidine results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr10:14,386,352...14,390,258
Ensembl chr10:14,386,352...14,390,258 		JBrowse link
G Trh thyrotropin releasing hormone decreases expression ISO Azacitidine results in decreased expression of TRH mRNA CTD PMID:19194470 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO Azacitidine results in decreased expression of TRIB1 mRNA CTD PMID:19194470 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trim8 tripartite motif-containing 8 increases expression ISO Azacitidine results in increased expression of TRIM8 mRNA CTD PMID:19194470 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513 		JBrowse link
G Tsc1 TSC complex subunit 1 multiple interactions ISO [Azacitidine affects the methylation of TSC1 promoter] which affects the expression of TSC1 mRNA CTD PMID:18538015 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc2 TSC complex subunit 2 decreases methylation
multiple interactions
increases expression		 ISO Azacitidine results in decreased methylation of TSC2 promoter
[Azacitidine affects the methylation of TSC2 promoter] which affects the expression of TSC2 mRNA
Azacitidine results in increased expression of TSC2 mRNA		 CTD PMID:18538015 PMID:19250671 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Azacitidine results in increased expression of TSHR mRNA CTD PMID:17679169 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
G Tspan32 tetraspanin 32 decreases expression ISO Azacitidine results in decreased expression of TSPAN32 mRNA CTD PMID:19194470 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445 		JBrowse link
G Ttk Ttk protein kinase multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA CTD PMID:18720364 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA CTD PMID:18720364 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Uhmk1 U2AF homology motif kinase 1 increases expression ISO Azacitidine results in increased expression of UHMK1 mRNA CTD PMID:20823114 NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292 		JBrowse link
G Ush2a usherin increases expression ISO Azacitidine results in increased expression of USH2A mRNA CTD PMID:20823114 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922 		JBrowse link
G Ushbp1 USH1 protein network component harmonin binding protein 1 decreases expression ISO Azacitidine results in decreased expression of USHBP1 mRNA CTD PMID:20823114 NCBI chr16:18,057,321...18,067,933
Ensembl chr16:18,057,326...18,067,877 		JBrowse link
G Vim vimentin decreases expression
increases expression
multiple interactions		 EXP
ISO		 Azacitidine results in decreased expression of VIM protein
Azacitidine results in increased expression of VIM mRNA; Azacitidine results in increased expression of VIM protein
[Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein		 CTD PMID:17105402 PMID:20823114 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Wdr47 WD repeat domain 47 decreases expression ISO Azacitidine results in decreased expression of WDR47 mRNA CTD PMID:19194470 NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739 		JBrowse link
G Wnt10b Wnt family member 10B increases expression EXP Azacitidine results in increased expression of WNT10B mRNA CTD PMID:27415467 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO Azacitidine results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 increases expression ISO Azacitidine results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968 		JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression
decreases methylation
increases expression		 ISO Azacitidine results in decreased expression of XAF1 mRNA alternative form
Azacitidine results in decreased methylation of XAF1 promoter
Azacitidine results in increased expression of XAF1 mRNA; Azacitidine results in increased expression of XAF1 protein		 CTD PMID:19077051 PMID:19549372 NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770 		JBrowse link
G Zfp189 zinc finger protein 189 decreases expression ISO Azacitidine results in decreased expression of ZNF189 mRNA CTD PMID:20823114 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121 		JBrowse link
G Zfp64 zinc finger protein 64 affects methylation ISO Azacitidine affects the methylation of ZFP64 promoter CTD PMID:17546590 NCBI chr 3:157,666,819...157,695,774
Ensembl chr 3:157,633,211...157,695,809 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression ISO Azacitidine results in increased expression of ZP3 mRNA CTD PMID:20823114 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513 		JBrowse link
9-(tetrahydrofuryl)adenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcg glucagon multiple interactions ISO 9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases expression ISO 9-(tetrahydro-2-furyl)-adenine results in decreased expression of PNPLA6 mRNA; 9-(tetrahydro-2-furyl)-adenine results in decreased expression of PNPLA6 protein CTD PMID:20380879 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 9-(tetrahydro-2-furyl)-adenine inhibits the reaction [methylmercuric chloride results in increased expression of PTGS2 protein] CTD PMID:28958600 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
acadesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression
multiple interactions		 EXP
ISO		 acadesine decreases expression of Abcb11 mRNA in primary hepatocytes
acadesine inhibits the reaction [picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 mRNA]]; acadesine inhibits the reaction [picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 protein]]		 CTD
RGD		 PMID:32976922 PMID:27090119 RGD:15090804 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP acadesine decreases expression of Abcc2 mRNA in primary hepatocytes RGD PMID:27090119 RGD:15090804 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation EXP acadesine results in increased phosphorylation of ACACA protein CTD PMID:22496244 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions EXP acadesine inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; acadesine inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] CTD PMID:26989860 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Agrp agouti related neuropeptide increases expression ISO acadesine results in increased expression of AGRP mRNA CTD PMID:32575098 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584 		JBrowse link
G Agt angiotensinogen multiple interactions EXP acadesine inhibits the reaction [AGT protein results in decreased expression of GJA1 protein]; acadesine inhibits the reaction [AGT protein results in decreased expression of GJA5 protein]; dorsomorphin inhibits the reaction [acadesine inhibits the reaction [AGT protein results in decreased expression of GJA1 protein]] CTD PMID:33676887 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
decreases phosphorylation		 ISO acadesine results in increased phosphorylation of AKT1 protein
acadesine results in decreased phosphorylation of AKT1 protein		 CTD PMID:22137261 PMID:25603053 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apln apelin multiple interactions ISO acadesine inhibits the reaction [Thioctic Acid results in increased expression of APLN mRNA]; acadesine inhibits the reaction [Thioctic Acid results in increased secretion of APLN protein] CTD PMID:21461750 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP acadesine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] CTD PMID:26989860 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO		 acadesine inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]
acadesine promotes the reaction [Artesunate results in decreased expression of BCL2 protein]		 CTD PMID:26989860 PMID:33002460 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO acadesine promotes the reaction [Zearalenone results in increased expression of BECN1 protein] CTD PMID:31982503 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO
EXP		 acadesine promotes the reaction [Isoniazid results in increased cleavage of CASP3 protein]
acadesine inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein]
acadesine results in increased cleavage of CASP3 protein		 CTD PMID:22137261 PMID:25603053 PMID:26989860 PMID:28556920 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO acadesine results in increased cleavage of CASP9 protein CTD PMID:22137261 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO acadesine promotes the reaction [Capsaicin results in increased expression of CDH1 protein] CTD PMID:36044967 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO acadesine promotes the reaction [Capsaicin results in decreased expression of CDH2 protein] CTD PMID:36044967 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cldn2 claudin 2 multiple interactions
decreases expression		 ISO acadesine promotes the reaction [solasodine results in decreased expression of CLDN2 protein]
acadesine results in decreased expression of CLDN2 protein		 CTD PMID:37121296 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP acadesine inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]; acadesine inhibits the reaction [glycidamide results in increased expression of CYP2E1 protein] CTD PMID:33545342 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO acadesine promotes the reaction [picroside II promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP8B1 mRNA]]; acadesine promotes the reaction [picroside II promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP8B1 protein]] CTD PMID:32976922 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP acadesine inhibits the reaction [Smoke results in increased expression of EDNRA protein] CTD PMID:36183783 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP acadesine inhibits the reaction [Smoke results in increased expression of EDNRB protein] CTD PMID:36183783 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of FASN protein] CTD PMID:33508418 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 multiple interactions ISO acadesine inhibits the reaction [Palmitates results in decreased expression of FNDC5 mRNA]; acadesine inhibits the reaction [Palmitates results in decreased expression of FNDC5 protein] CTD PMID:36375515 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP acadesine inhibits the reaction [AGT protein results in decreased expression of GJA1 protein]; dorsomorphin inhibits the reaction [acadesine inhibits the reaction [AGT protein results in decreased expression of GJA1 protein]] CTD PMID:33676887 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 multiple interactions EXP acadesine inhibits the reaction [AGT protein results in decreased expression of GJA5 protein] CTD PMID:33676887 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein]; acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of GPAM protein] CTD PMID:33508418 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO acadesine promotes the reaction [Capsaicin affects the localization of MAP1LC3A protein] CTD PMID:36044967 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO acadesine promotes the reaction [Artesunate results in increased lipidation of MAP1LC3B protein] CTD PMID:33002460 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP acadesine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK1 protein]; acadesine inhibits the reaction [glycidamide results in increased phosphorylation of MAPK1 protein] CTD PMID:33545342 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP acadesine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK3 protein]; acadesine inhibits the reaction [glycidamide results in increased phosphorylation of MAPK3 protein] CTD PMID:33545342 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO acadesine results in decreased expression of MEF2C mRNA CTD PMID:15864539 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]
acadesine promotes the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; acadesine promotes the reaction [Capsaicin results in decreased phosphorylation of MTOR protein]		 CTD PMID:31982503 PMID:33002460 PMID:36044967 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions		 EXP
ISO		 acadesine decreases expression of Nr1h4 mRNA and protein in primary hepatocytes
acadesine inhibits the reaction [picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]]; acadesine inhibits the reaction [picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein]]		 CTD
RGD		 PMID:32976922 PMID:27090119 RGD:15090804 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
increases expression		 ISO acadesine inhibits the reaction [Isoniazid results in decreased expression of NRF1 protein]
acadesine results in increased expression of NRF1 protein		 CTD PMID:28556920 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Ocln occludin multiple interactions ISO acadesine promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of OCLN protein] CTD PMID:33400020 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO acadesine promotes the reaction [Artesunate results in increased cleavage of PARP1 protein] CTD PMID:33002460 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP acadesine inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; acadesine inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein] CTD PMID:26989860 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression		 ISO
EXP		 acadesine inhibits the reaction [Isoniazid results in decreased expression of PPARGC1A protein]
acadesine results in increased expression of PPARGC1A mRNA
Dietary Fats promotes the reaction [acadesine results in increased expression of PPARGC1A mRNA]
acadesine results in increased expression of PPARGC1A protein		 CTD PMID:22496244 PMID:28556920 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions		 EXP
ISO		 acadesine increases phosphorylation of Prkaa1 in primary hepatocytes
acadesine results in increased phosphorylation of PRKAA1 protein
acadesine inhibits the reaction [Smoke results in decreased phosphorylation of PRKAA1 protein]
acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA1 protein]		 CTD
RGD		 PMID:22815988 PMID:33676887 PMID:36044967 PMID:36183783 PMID:37121296 More... RGD:15090804 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA2 protein] CTD PMID:36044967 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acadesine inhibits the reaction [[Fluorouracil results in increased expression of PTGS2 protein] which results in increased abundance of and results in increased secretion of Dinoprostone]; acadesine inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein] CTD PMID:15896711 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO acadesine results in decreased expression of RHOA protein CTD PMID:37121296 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31982503 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
increases expression		 ISO acadesine inhibits the reaction [Isoniazid results in decreased expression of SIRT1 protein]
acadesine results in increased expression of SIRT1 protein		 CTD PMID:28556920 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP acadesine decreases expression of Slc10a1 mRNA in primary hepatocytes RGD PMID:27090119 RGD:15090804 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO acadesine results in increased expression of SLC2A1 mRNA CTD PMID:15864539 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP acadesine decreases expression of Slco1a4 mRNA in primary hepatocytes RGD PMID:27090119 RGD:15090804 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of SREBF1 protein] CTD PMID:33508418 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO acadesine inhibits the reaction [SEW2871 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of TJP1 protein]]; acadesine promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of TJP1 protein] CTD PMID:33400020 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO acadesine promotes the reaction [Artesunate results in increased phosphorylation of ULK1 protein] CTD PMID:33002460 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Zfp57 zinc finger protein 57 multiple interactions ISO acadesine inhibits the reaction [Palmitates results in increased expression of ZFP57 mRNA]; acadesine inhibits the reaction [Palmitates results in increased expression of ZFP57 protein] CTD PMID:36375515 NCBI chr20:1,521,323...1,534,884
Ensembl chr20:1,521,323...1,529,846 		JBrowse link
AICA ribonucleotide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP AICA ribonucleotide results in decreased expression of ABCB11 mRNA CTD PMID:27090119 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP AICA ribonucleotide results in decreased expression of ABCC2 mRNA CTD PMID:27090119 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to XPO1 protein]; AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]; AICA ribonucleotide results in decreased expression of and affects the localization of ABL1 protein mutant form CTD PMID:33070465 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation
multiple interactions
increases expression		 ISO
EXP		 AICA ribonucleotide results in increased phosphorylation of ACACA protein
AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of and results in decreased phosphorylation of ACACA protein]; AICA ribonucleotide results in decreased expression of and results in increased phosphorylation of ACACA protein
AICA ribonucleotide results in increased expression of ACACA protein modified form		 CTD PMID:15297373 PMID:16020477 PMID:16873680 PMID:20080969 PMID:25743752 More... NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta increases phosphorylation ISO AICA ribonucleotide results in increased phosphorylation of ACACB protein CTD PMID:16873680 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions
increases expression		 EXP
ISO		 AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of ACADM mRNA]
AICA ribonucleotide results in increased expression of ACADM mRNA; AICA ribonucleotide results in increased expression of ACADM protein		 CTD PMID:19699196 PMID:25743752 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:27688165 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
multiple interactions		 ISO
EXP		 AICA ribonucleotide results in increased expression of ADIPOQ protein
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]		 CTD PMID:20980258 PMID:25108154 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in decreased oxidation of Fatty Acids]; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]] CTD PMID:15806154 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G App amyloid beta precursor protein decreases expression ISO AICA ribonucleotide results in decreased expression of APP protein modified form CTD PMID:20080969 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arg1 arginase 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA] CTD PMID:25108154 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Ethanol results in decreased expression of ATG5 protein] CTD PMID:24582693 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 EXP
ISO		 AICA ribonucleotide results in increased expression of BECN1 protein
AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to BECN1 protein]; AICA ribonucleotide results in increased expression of and affects the localization of BECN1 protein
AICA ribonucleotide promotes the reaction [4-nonylphenol results in increased expression of BECN1 protein]		 CTD PMID:28041982 PMID:33070465 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 EXP
ISO		 AICA ribonucleotide results in increased activity of CASP3 protein
AICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP3 protein]		 CTD PMID:16469385 PMID:21906609 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO AICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein] CTD PMID:21906609 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 increases activity EXP AICA ribonucleotide results in increased activity of CASP9 protein CTD PMID:16469385 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
increases expression		 ISO AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]
AICA ribonucleotide results in increased expression of CAT mRNA; AICA ribonucleotide results in increased expression of CAT protein		 CTD PMID:25065674 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression		 EXP
ISO		 AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]
AICA ribonucleotide results in decreased expression of CCL2 mRNA
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of CCL2 mRNA]		 CTD PMID:24465016 PMID:25108154 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA] CTD PMID:21745629 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]
AICA ribonucleotide results in decreased expression of CCNA2 mRNA; AICA ribonucleotide results in decreased expression of CCNA2 protein		 CTD PMID:12730239 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
AICA ribonucleotide results in decreased expression of CCNB1 mRNA; AICA ribonucleotide results in decreased expression of CCNB1 protein		 CTD PMID:12730239 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO AICA ribonucleotide results in increased expression of and affects the localization of CD36 protein CTD PMID:28038998 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions		 ISO AICA ribonucleotide results in decreased expression of CEBPA protein
AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of CEBPA protein]		 CTD PMID:27103584 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases phosphorylation ISO AICA ribonucleotide results in increased phosphorylation of CEBPB protein CTD PMID:28038998 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein] CTD PMID:12519745 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:27688165 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions		 ISO AICA ribonucleotide results in increased expression of CPT1A mRNA; AICA ribonucleotide results in increased expression of CPT1A protein
AICA ribonucleotide inhibits the reaction [TP53 gene mutant form results in increased expression of CPT1A protein]
dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of CPT1A mRNA]		 CTD PMID:24465016 PMID:25743752 PMID:33070465 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions EXP AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B protein] CTD PMID:19699196 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression		 ISO [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 mRNA; [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 protein; AICA ribonucleotide inhibits the reaction [[HDAC5 protein binds to MEF2 protein] which binds to CTNNB1 promoter]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 mRNA]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 protein]
AICA ribonucleotide results in increased expression of CTNNB1 mRNA; AICA ribonucleotide results in increased expression of CTNNB1 protein		 CTD PMID:21454484 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] CTD PMID:21195169 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein] CTD PMID:21195169 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions EXP AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]] CTD PMID:22815988 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases phosphorylation ISO AICA ribonucleotide results in decreased phosphorylation of EIF2S1 protein CTD PMID:22898769 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation		 ISO
EXP		 AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]
AICA ribonucleotide results in decreased phosphorylation of EIF4EBP1 protein
AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]		 CTD PMID:15806154 PMID:21195169 PMID:28041982 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions
decreases localization		 ISO AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]; AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
AICA ribonucleotide results in decreased localization of ELAVL1 protein		 CTD PMID:12730239 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases expression
increases phosphorylation
increases activity		 ISO AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]; AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of SOD2 mRNA]
AICA ribonucleotide results in increased expression of FOXO1 protein
AICA ribonucleotide results in increased phosphorylation of FOXO1 protein
AICA ribonucleotide results in increased activity of FOXO1 protein		 CTD PMID:25065674 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [FSHB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:16020477 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP AICA ribonucleotide results in decreased expression of G6PC1 mRNA CTD PMID:19664596 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gpr68 G protein-coupled receptor 68 multiple interactions ISO AICA ribonucleotide inhibits the reaction [TNF protein promotes the reaction [Oxygen deficiency results in increased expression of GPR68 mRNA]]; AICA ribonucleotide inhibits the reaction [TNF protein results in increased expression of GPR68 mRNA] CTD PMID:28174749 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions EXP GRB2 protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression ISO AICA ribonucleotide results in increased expression of GSTK1 protein CTD PMID:20980258 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions
increases phosphorylation		 ISO [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 mRNA; [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 protein; AICA ribonucleotide inhibits the reaction [[HDAC5 protein binds to MEF2 protein] which binds to CTNNB1 promoter] CTD PMID:21454484 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO AICA ribonucleotide results in decreased expression of HNF4A mRNA CTD PMID:24428821 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP AICA ribonucleotide results in decreased expression of HSD3B1 mRNA; AICA ribonucleotide results in decreased expression of HSD3B1 protein CTD PMID:16020477 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein] CTD PMID:16020477 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of IL1B mRNA] CTD PMID:24465016 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression		 EXP
ISO		 AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]
AICA ribonucleotide results in decreased expression of IL6 mRNA
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of IL6 mRNA]		 CTD PMID:24465016 PMID:25108154 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D1 protein]; AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein] CTD PMID:24343960 PMID:26627467 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Insr insulin receptor multiple interactions
decreases activity
decreases expression		 ISO 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased activity of INSR promoter]; 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR mRNA]; 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR protein]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased activity of INSR promoter]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR mRNA]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR protein]
AICA ribonucleotide results in decreased expression of INSR mRNA; AICA ribonucleotide results in decreased expression of INSR protein		 CTD PMID:15694368 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 affects response to substance ISO KCNJ11 protein affects the susceptibility to AICA ribonucleotide CTD PMID:24498880 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Klf15 KLF transcription factor 15 decreases expression ISO AICA ribonucleotide results in decreased expression of KLF15 mRNA CTD PMID:24428821 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases activity EXP AICAR increases activity of Map3k7 protein in cardiac muscle cells RGD PMID:17085580 RGD:155791450 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP
ISO		 AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein]
AICA ribonucleotide results in increased phosphorylation of MAPK1 protein
AICA ribonucleotide results in decreased phosphorylation of MAPK1 protein		 CTD PMID:16020477 PMID:28038998 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP
ISO		 AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [FSHB protein results in increased phosphorylation of MAPK3 protein]; MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of MAPK3 protein]
AICA ribonucleotide results in increased phosphorylation of MAPK3 protein
AICA ribonucleotide results in decreased phosphorylation of MAPK3 protein		 CTD PMID:11978788 PMID:16020477 PMID:28038998 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mfn1 mitofusin 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN1 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN1 protein] CTD PMID:27792760 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN2 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN2 protein] CTD PMID:27792760 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of MMP13 protein] CTD PMID:27688165 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO AICA ribonucleotide results in decreased activity of MMP2 protein CTD PMID:20590612 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO AICA ribonucleotide results in decreased activity of MMP9 protein CTD PMID:20590612 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpst mercaptopyruvate sulfurtransferase decreases expression EXP AICA ribonucleotide results in decreased expression of MPST mRNA CTD PMID:35577173 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases activity
decreases phosphorylation
multiple interactions		 ISO
EXP		 AICA ribonucleotide results in decreased activity of MTOR protein
AICA ribonucleotide results in decreased phosphorylation of MTOR protein
AICA ribonucleotide promotes the reaction [4-nonylphenol results in decreased phosphorylation of MTOR protein]
AICA ribonucleotide promotes the reaction [Cadmium results in decreased phosphorylation of MTOR protein]		 CTD PMID:19625624 PMID:21767558 PMID:27363783 PMID:28041982 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF1 protein] CTD PMID:21195169 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] CTD PMID:21195169 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF4 protein] CTD PMID:21195169 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:22025971 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO		 AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]		 CTD PMID:24465016 PMID:25108154 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]] CTD PMID:25108154 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO AICA ribonucleotide results in decreased expression of NR0B2 mRNA CTD PMID:24428821 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP AICA ribonucleotide results in decreased expression of NR1H4 mRNA; AICA ribonucleotide results in decreased expression of NR1H4 protein CTD PMID:27090119 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Phenobarbital results in increased localization of and results in increased activity of NR1I3 protein]; AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]] CTD PMID:20686344 PMID:22815988 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
increases expression		 EXP dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] CTD PMID:20438809 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of OPA1 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of OPA1 protein] CTD PMID:27792760 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA protein] CTD PMID:19699196 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP
ISO		 AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]
AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of PPARG protein]		 CTD PMID:25108154 PMID:27688165 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression
decreases expression		 EXP
ISO		 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of PPARGC1A mRNA]
AICA ribonucleotide results in decreased expression of PPARGC1A mRNA
AICA ribonucleotide inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein]; dorsomorphin promotes the reaction [AICA ribonucleotide results in decreased expression of PPARGC1A mRNA]
AICA ribonucleotide inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARGC1A protein]		 CTD PMID:20438809 PMID:23090186 PMID:24428821 PMID:25522270 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions
increases expression
increases activity		 EXP
ISO		 AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of PRKAA1 protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of PRKAA1 protein]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein]
AICA ribonucleotide promotes the reaction [Quercetin results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA1 protein; PRKAA1 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]; Quercetin promotes the reaction [AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA1 protein]
AICA ribonucleotide results in increased expression of PRKAA1 protein modified form
[AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein] which results in decreased secretion of Progesterone; AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein]; AICA ribonucleotide inhibits the reaction [Sodium Chloride, Dietary results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; AICA ribonucleotide inhibits the reaction [Sodium Chloride, Dietary results in increased expression of PRKAA1 mRNA]
AICA ribonucleotide results in increased activity of PRKAA1 protein		 CTD PMID:12519745 PMID:16020477 PMID:16873680 PMID:19293639 PMID:20349193 More... NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases phosphorylation		 ISO
EXP		 AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA2 protein; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]
PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]]
AICA ribonucleotide results in increased phosphorylation of PRKAA2 protein
PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 mRNA]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 protein]		 CTD PMID:15806154 PMID:16873680 PMID:18482975 PMID:21205922 PMID:21454484 More... NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Prkcz protein kinase C, zeta multiple interactions
increases activity		 EXP 1-Butanol inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; Genistein inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; GRB2 protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Pten phosphatase and tensin homolog increases response to substance ISO PTEN protein results in increased susceptibility to AICA ribonucleotide CTD PMID:19625624 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22025971 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PTK2B protein; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of MAPK3 protein]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of RAC1 protein] CTD PMID:21195169 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions EXP RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]		 CTD PMID:22058332 PMID:25108154 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO AICA ribonucleotide results in decreased phosphorylation of RPS6 protein CTD PMID:19625624 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
increases phosphorylation		 EXP AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein]
AICA ribonucleotide results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:15342961 PMID:21195169 PMID:28041982 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
increases expression		 ISO
EXP		 AICA ribonucleotide inhibits the reaction [Glucose results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of SIRT1 protein]
AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of SIRT1 protein]
[Niacinamide results in decreased activity of SIRT1 protein] which results in decreased susceptibility to AICA ribonucleotide		 CTD PMID:22058332 PMID:23090186 PMID:24465016 PMID:25108154 PMID:27688165 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP AICA ribonucleotide results in decreased expression of SLC10A1 mRNA CTD PMID:27090119 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases activity ISO AICA ribonucleotide results in decreased activity of SLC15A1 protein CTD PMID:22108913 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions
increases localization		 EXP
ISO		 1-Butanol inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; Genistein inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; U 0126 inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; wortmannin inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]
AICA ribonucleotide inhibits the reaction [Palmitates results in decreased expression of SLC2A4 mRNA]		 CTD PMID:11978788 PMID:21802492 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP AICA ribonucleotide results in decreased expression of SLCO1A2 mRNA CTD PMID:27090119 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of SOD2 mRNA]
AICA ribonucleotide results in increased expression of SOD2 mRNA; AICA ribonucleotide results in increased expression of SOD2 protein		 CTD PMID:25065674 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 ISO [AICA ribonucleotide co-treated with Sirolimus] results in increased expression of SQSTM1 protein; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased expression of SQSTM1 protein] CTD PMID:33070465 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased phosphorylation of STK11 protein] CTD PMID:27688165 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Tbc1d1 TBC1 domain family member 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D1 protein] CTD PMID:26627467 NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein] CTD PMID:24343960 PMID:26627467 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of MMP13 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of PPARG protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased phosphorylation of STK11 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein] CTD PMID:27688165 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein] CTD PMID:27688165 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
AICA ribonucleotide inhibits the reaction [TNF protein promotes the reaction [Oxygen deficiency results in increased expression of GPR68 mRNA]]; AICA ribonucleotide inhibits the reaction [TNF protein results in increased expression of GPR68 mRNA]
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]		 CTD PMID:22025971 PMID:25108154 PMID:28174749 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A protein] CTD PMID:22025971 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases phosphorylation		 ISO [Resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 protein]; AICA ribonucleotide inhibits the reaction [TP53 gene mutant form results in increased expression of CPT1A protein]; AICA ribonucleotide promotes the reaction [TP53 gene mutant form results in increased phosphorylation of ULK1 protein]; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased expression of SQSTM1 protein]; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased phosphorylation of ULK1 protein]
AICA ribonucleotide results in increased phosphorylation of TP53 protein		 CTD PMID:26188290 PMID:33070465 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein] CTD PMID:29031535 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Indican results in decreased expression of UCP2 mRNA] CTD PMID:25703824 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO AICA ribonucleotide promotes the reaction [TP53 gene mutant form results in increased phosphorylation of ULK1 protein]; AICA ribonucleotide results in increased expression of and results in increased phosphorylation of ULK1 protein; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased phosphorylation of ULK1 protein] CTD PMID:33070465 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO AICA ribonucleotide inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased secretion of VEGFA protein] CTD PMID:30724446 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xpo1 exportin 1 multiple interactions ISO AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to XPO1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to YWHAQ protein] CTD PMID:33070465 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta multiple interactions ISO AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to YWHAQ protein] CTD PMID:33070465 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
emtricitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Emtricitabine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Dck deoxycytidine kinase multiple interactions
affects binding		 ISO DCK protein results in increased phosphorylation of and results in increased activity of Emtricitabine
Emtricitabine binds to DCK protein		 CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions		 ISO Emtricitabine results in decreased expression of PRKN protein
[Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein		 CTD PMID:31545371 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein CTD PMID:31545371 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
floxuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
decreases response to substance		 ISO APEX1 protein mutant form results in increased susceptibility to Floxuridine
APEX1 protein results in decreased susceptibility to Floxuridine		 CTD PMID:19470598 PMID:22194930 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Atr ATR serine/threonine kinase decreases response to substance ISO ATR protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Floxuridine CTD PMID:25354864 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases activity		 ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK2 protein
Floxuridine results in increased activity of CHEK2 protein		 CTD PMID:21613406 PMID:22194930 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
decreases response to substance		 ISO olaparib inhibits the reaction [MLH1 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 multiple interactions
decreases response to substance		 ISO olaparib inhibits the reaction [MSH2 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR protein affects the susceptibility to Floxuridine CTD PMID:18202788 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases response to substance ISO PARP1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 affects response to substance
decreases response to substance		 ISO TIMP3 protein affects the susceptibility to Floxuridine
TIMP3 gene modified form results in decreased susceptibility to Floxuridine		 CTD PMID:18202788 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tk1 thymidine kinase 1 increases expression ISO Floxuridine results in increased expression of TK1 protein CTD PMID:16951200 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity		 ISO Floxuridine results in increased expression of TP53 protein
Floxuridine affects the activity of TP53 protein		 CTD PMID:19015155 PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tyms thymidylate synthetase affects response to substance
increases response to substance
decreases response to substance		 ISO TYMS protein affects the susceptibility to Floxuridine
TYMS results in increased susceptibility to Floxuridine
TYMS protein results in decreased susceptibility to Floxuridine		 CTD PMID:2537495 PMID:10482907 PMID:15040806 PMID:17018589 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ung uracil-DNA glycosylase affects expression
increases response to substance
affects stability		 ISO Floxuridine affects the expression of UNG mRNA; Floxuridine affects the expression of UNG protein
UNG protein results in increased susceptibility to Floxuridine
Floxuridine affects the stability of UNG protein alternative form		 CTD PMID:16951200 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases response to substance ISO XRCC1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Floxuridine CTD PMID:21785230 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
flucytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Flucytosine results in decreased expression of BCL2 protein CTD PMID:15592511 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Flucytosine results in increased expression of MDM2 protein CTD PMID:15592511 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Flucytosine results in increased expression of TP53 protein CTD PMID:15592511 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
lamivudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Lamivudine results in decreased expression of ACTA2 protein CTD PMID:11738102 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA CTD PMID:16931933 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877 		JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Alb albumin affects binding ISO Lamivudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA CTD PMID:18313992 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5F1C mRNA CTD PMID:18313992 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5MC3 mRNA CTD PMID:18313992 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279 		JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5MF mRNA CTD PMID:18313992 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5PD mRNA CTD PMID:18313992 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5PF mRNA CTD PMID:18313992 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5PO mRNA CTD PMID:18313992 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA CTD PMID:18313992 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Lamivudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA CTD PMID:16931933 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein] CTD PMID:36309141 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in decreased activity of CAT protein CTD PMID:34118364 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression		 ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Lamivudine results in decreased expression of CCNA2 mRNA		 CTD PMID:15784690 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA CTD PMID:15784690 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions		 ISO Lamivudine results in decreased expression of CCND2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA		 CTD PMID:15784690 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression		 ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
Lamivudine results in decreased expression of CCNE2 mRNA		 CTD PMID:15784690 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions		 ISO Lamivudine results in decreased expression of CDKN1A mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA		 CTD PMID:15784690 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Lamivudine results in decreased expression of COL3A1 protein CTD PMID:11738102 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA CTD PMID:18313992 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA CTD PMID:18313992 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA CTD PMID:18313992 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963 		JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA CTD PMID:18313992 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA CTD PMID:18313992 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Crat carnitine O-acetyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255 		JBrowse link
G Cul7 cullin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA CTD PMID:18313992 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO DCK protein results in increased phosphorylation of and results in increased activity of Lamivudine CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO Lamivudine results in increased expression of DDIT3 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA		 CTD PMID:15784690 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion		 ISO coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA CTD PMID:11741158 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC1 mRNA CTD PMID:16931933 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609 		JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Grhl2 grainyhead-like transcription factor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gypa glycophorin A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased mutagenesis of GYPA gene CTD PMID:17358027 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hist1h4b histone cluster 1 H4 family member B multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B2 mRNA CTD PMID:18313992 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B3 mRNA CTD PMID:18313992 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH2 mRNA CTD PMID:18313992 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH3A mRNA CTD PMID:18313992 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of IDH3G mRNA CTD PMID:18313992 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171 		JBrowse link
G Ifng interferon gamma increases expression ISO Lamivudine results in increased expression of IFNG protein CTD PMID:16250037 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein] CTD PMID:36309141 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IL27RA mRNA CTD PMID:15784690 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of INPP5E mRNA CTD PMID:18313992 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450 		JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNA CTD PMID:15784690 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635 		JBrowse link
G Kifc2 kinesin family member C2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA CTD PMID:16931933 NCBI chr 7:108,380,634...108,388,364
Ensembl chr 7:108,376,011...108,388,484 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KLF4 mRNA CTD PMID:15784690 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164 		JBrowse link
G Krt7 keratin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNA CTD PMID:15784690 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Kynu kynureninase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KYNU mRNA CTD PMID:15784690 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of LAMB3 mRNA CTD PMID:15784690 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lep leptin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LEP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA CTD PMID:16931933 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lpl lipoprotein lipase decreases expression
multiple interactions		 ISO Lamivudine results in decreased expression of LPL mRNA
[Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LPL mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of LPL mRNA		 CTD PMID:11741158 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mars1 methionyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MARS1 mRNA CTD PMID:15784690 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495 		JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression		 ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNA
Lamivudine results in increased expression of ME1 mRNA		 CTD PMID:11741158 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN1 mRNA CTD PMID:18313992 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:36,709,564...37,485,810
Ensembl chr 7:37,260,321...37,474,571 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lamivudine results in increased expression of MMP1 protein CTD PMID:15309715 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of MPO protein CTD PMID:34118364 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of MRAP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX2 mRNA CTD PMID:18313992 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX3 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND2 mRNA CTD PMID:18313992 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942 		JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND5 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MTHFD2 mRNA CTD PMID:15784690 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654 		JBrowse link
G Ndufa4 Ndufa4, mitochondrial complex associated multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFA4 mRNA CTD PMID:18313992 NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAB1 mRNA CTD PMID:18313992 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099 		JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAF1 mRNA CTD PMID:18313992 NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212 		JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB3 mRNA CTD PMID:18313992 NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446 		JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB5 mRNA CTD PMID:18313992 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589 		JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFB9 mRNA CTD PMID:18313992 NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFC1 mRNA CTD PMID:18313992 NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFS1 mRNA CTD PMID:18313992 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NIBAN1 mRNA CTD PMID:15784690 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729 		JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation		 ISO coenzyme Q10 inhibits the reaction [Lamivudine results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA CTD PMID:11706060 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874 		JBrowse link
G Nxnl2 nucleoredoxin-like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NXNL2 mRNA CTD PMID:16931933 NCBI chr17:14,031,151...14,035,897
Ensembl chr17:14,031,153...14,036,189 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of OAZ3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OGT mRNA CTD PMID:15784690 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPA1 mRNA CTD PMID:18313992 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPRL1 mRNA CTD PMID:16931933 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PCK2 mRNA CTD PMID:15784690 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PFKFB3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Pgap6 post-GPI attachment to proteins 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PGAP6 mRNA CTD PMID:16931933 NCBI chr10:15,138,918...15,148,431
Ensembl chr10:15,138,959...15,148,431 		JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:132,656,658...132,699,720
Ensembl chr  X:132,656,672...132,699,127 		JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIDD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702 		JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PPN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:14,285,864...14,298,481
Ensembl chr  X:14,285,871...14,298,481 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PRDM1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PSAT1 mRNA CTD PMID:15784690 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Rabepk Rab9 effector protein with kelch motifs multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RABEPK mRNA CTD PMID:15784690 NCBI chr 3:18,061,299...18,083,191
Ensembl chr 3:18,061,574...18,083,191 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNA CTD PMID:15784690 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330 		JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNA CTD PMID:15784690 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572 		JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNA CTD PMID:15784690 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000 		JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:55,692,410...55,699,910
Ensembl chr10:55,692,417...55,699,933 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of S100A8 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SDHB mRNA CTD PMID:18313992 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Serinc1 serine incorporator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SERINC1 mRNA CTD PMID:16931933 NCBI chr20:36,850,062...36,868,999
Ensembl chr20:36,850,076...36,896,691 		JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN1 mRNA CTD PMID:18313992 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN2 mRNA CTD PMID:18313992 NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411 		JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN4 mRNA CTD PMID:18313992 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA CTD PMID:18313992 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A4 mRNA CTD PMID:15784690 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A5 mRNA CTD PMID:15784690 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases uptake ISO SLC22A1 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake ISO SLC22A2 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake ISO SLC22A3 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A12 mRNA CTD PMID:18313992 NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A15 mRNA CTD PMID:18313992 NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010 		JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir]; SLC25A19 protein affects the susceptibility to [Zidovudine co-treated with Lamivudine co-treated with Indinavir]
[Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A19 mRNA		 CTD PMID:15951836 PMID:18313992 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447 		JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A2 mRNA CTD PMID:18313992 NCBI chr18:29,452,943...29,456,324
Ensembl chr18:29,453,582...29,460,383 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A20 mRNA CTD PMID:18313992 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512 		JBrowse link
G Slc25a29 solute carrier family 25 member 29 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNA CTD PMID:18313992 NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940 		JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A3 mRNA CTD PMID:18313992 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A4 mRNA CTD PMID:18313992 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions ISO Lamivudine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine] CTD PMID:10772724 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC31A1 mRNA CTD PMID:15784690 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC3A2 mRNA CTD PMID:15784690 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNA CTD PMID:18313992 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression		 ISO [Lamivudine co-treated with IFNA2 protein] results in increased expression of SLC6A4 mRNA; Lamivudine promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Lamivudine results in increased expression of and results in increased activity of SLC6A4 protein
Lamivudine results in increased expression of SLC6A4 mRNA		 CTD PMID:16476009 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of STAR mRNA CTD PMID:18313992 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of STC2 mRNA CTD PMID:15784690 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Sub1 SUB1 regulator of transcription multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SUB1 mRNA CTD PMID:16931933 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436 		JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TCEA1 mRNA CTD PMID:15784690 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Lamivudine results in decreased expression of TGFB1 protein CTD PMID:15309715 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM17B mRNA CTD PMID:18313992 NCBI chr  X:14,596,330...14,603,491
Ensembl chr  X:14,594,577...14,603,416 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA CTD PMID:18313992 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Lamivudine results in decreased expression of TIMP1 protein CTD PMID:15309715 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tk2 thymidine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TK2 mRNA CTD PMID:18313992 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein] CTD PMID:36309141 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TRIB3 mRNA CTD PMID:15784690 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:97,902,349...97,923,268
Ensembl chr 8:97,902,353...97,923,268 		JBrowse link
G Twnk twinkle mtDNA helicase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TWNK mRNA CTD PMID:18313992 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYRP1 mRNA CTD PMID:15784690 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRB mRNA CTD PMID:18313992 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRC1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of UQCRC2 mRNA CTD PMID:18313992 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDAC1 mRNA CTD PMID:18313992 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA CTD PMID:11741158 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA CTD PMID:16931933 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of WARS1 mRNA CTD PMID:15784690 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of WNT10A mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of YARS1 mRNA CTD PMID:15784690 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833 		JBrowse link
N(4)-hydroxycytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases expression ISO N(4)-hydroxycytidine results in increased expression of AARS mRNA CTD PMID:37748715 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ABCF3 mRNA CTD PMID:37748715 NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211 		JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ACE mRNA CTD PMID:37748715 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adap2 ArfGAP with dual PH domains 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADAP2 mRNA CTD PMID:37748715 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604 		JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRA2 mRNA CTD PMID:37748715 NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483 		JBrowse link
G Adgra3 adhesion G protein-coupled receptor A3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRA3 mRNA CTD PMID:37748715 NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRG1 mRNA CTD PMID:37748715 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Akirin1 akirin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AKIRIN1 mRNA CTD PMID:37748715 NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression ISO N(4)-hydroxycytidine results in increased expression of ALDH18A1 mRNA CTD PMID:37748715 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Alkbh5 alkB homolog 5, RNA demethylase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ALKBH5 mRNA CTD PMID:37748715 NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331 		JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of APBB1IP mRNA CTD PMID:37748715 NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010 		JBrowse link
G Apela apelin receptor early endogenous ligand decreases expression ISO N(4)-hydroxycytidine results in decreased expression of APELA mRNA CTD PMID:37748715 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARIH2 mRNA CTD PMID:37748715 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Arl14ep ADP-ribosylation factor like GTPase 14 effector protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARL14EP mRNA CTD PMID:37748715 NCBI chr 3:93,441,952...93,454,282
Ensembl chr 3:93,443,183...93,454,155 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARNT mRNA CTD PMID:37748715 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARRDC4 mRNA CTD PMID:37748715 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290 		JBrowse link
G Asb8 ankyrin repeat and SOCS box-containing 8 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ASB8 mRNA CTD PMID:37748715 NCBI chr 7:129,261,397...129,297,492
Ensembl chr 7:129,261,397...129,297,485 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression
multiple interactions		 ISO N(4)-hydroxycytidine results in increased expression of ASNS mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of ASNS mRNA]		 CTD PMID:37748715 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Ate1 arginyltransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATE1 mRNA CTD PMID:37748715 NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908 		JBrowse link
G Atf2 activating transcription factor 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF2 mRNA CTD PMID:37748715 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO N(4)-hydroxycytidine results in increased expression of ATF3 mRNA CTD PMID:37748715 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF4 mRNA CTD PMID:37748715 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF5 mRNA CTD PMID:37748715 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF6 mRNA CTD PMID:37748715 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AUP1 mRNA CTD PMID:37748715 NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346 		JBrowse link
G Avil advillin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AVIL mRNA CTD PMID:37748715 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) decreases expression ISO N(4)-hydroxycytidine results in decreased expression of B3GALNT1 mRNA CTD PMID:37748715 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332 		JBrowse link
G Bbx BBX high mobility group box domain containing decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BBX mRNA CTD PMID:37748715 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BGLAP mRNA CTD PMID:37748715 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Brms1l BRMS1 like transcriptional repressor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BRMS1L mRNA CTD PMID:37748715 NCBI chr 6:73,266,673...73,300,630
Ensembl chr 6:73,266,691...73,300,631 		JBrowse link
G Calml4 calmodulin-like 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CALML4 mRNA CTD PMID:37748715 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CARHSP1 mRNA CTD PMID:37748715 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LRRC16A mRNA CTD PMID:37748715 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 increases expression ISO N(4)-hydroxycytidine results in increased expression of CARS mRNA CTD PMID:37748715 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941 		JBrowse link
G Cbx7 chromobox 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CBX7 mRNA CTD PMID:37748715 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CCNB2 mRNA CTD PMID:37748715 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Cd68 Cd68 molecule decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CD68 mRNA CTD PMID:37748715 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CDCA3 mRNA CTD PMID:37748715 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CEBPG mRNA CTD PMID:37748715 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569 		JBrowse link
G Cep170 centrosomal protein 170 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CEP170 mRNA CTD PMID:37748715 NCBI chr13:88,669,672...88,754,011
Ensembl chr13:88,670,358...88,732,226 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of CHAC1 mRNA] CTD PMID:37748715 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COA7 mRNA CTD PMID:37748715 NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199 		JBrowse link
G Commd5 COMM domain containing 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COMMD5 mRNA CTD PMID:37748715 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COX6A2 mRNA CTD PMID:37748715 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CPT1A mRNA CTD PMID:37748715 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cryzl1 crystallin zeta like 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CRYZL1 mRNA CTD PMID:37748715 NCBI chr11:30,933,140...30,977,936
Ensembl chr11:30,933,144...30,977,867 		JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CSF3R mRNA CTD PMID:37748715 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881 		JBrowse link
G Ctps2 CTP synthase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CTPS2 mRNA CTD PMID:37748715 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Cyb5b cytochrome b5 type B multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Dcaf15 DDB1 and CUL4 associated factor 15 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DCAF15 mRNA CTD PMID:37748715 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277 		JBrowse link
G Ddhd2 DDHD domain containing 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDHD2 mRNA CTD PMID:37748715 NCBI chr16:66,319,469...66,349,025
Ensembl chr16:66,319,466...66,349,023 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of DDIT3 mRNA] CTD PMID:37748715 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO N(4)-hydroxycytidine results in increased expression of DDIT4 mRNA CTD PMID:37748715 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx19b DEAD-box helicase 19B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDX19B mRNA CTD PMID:37748715 NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259 		JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDX4 mRNA CTD PMID:37748715 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Def8 differentially expressed in FDCP 8 homolog decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DEF8 mRNA CTD PMID:37748715 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638 		JBrowse link
G Dnajc5g DnaJ heat shock protein family (Hsp40) member C5 gamma decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DNAJC5G mRNA CTD PMID:37748715 NCBI chr 6:25,260,087...25,264,251
Ensembl chr 6:25,260,088...25,264,152 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DNMT1 mRNA CTD PMID:37748715 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP11 mRNA CTD PMID:37748715 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181 		JBrowse link
G Dusp16 dual specificity phosphatase 16 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP16 mRNA CTD PMID:37748715 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP19 mRNA CTD PMID:37748715 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DYNLL1 mRNA CTD PMID:37748715 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Dyrk4 dual specificity tyrosine phosphorylation regulated kinase 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DYRK4 mRNA CTD PMID:37748715 NCBI chr 4:159,715,658...159,757,660
Ensembl chr 4:159,715,417...159,757,627 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of E2F8 mRNA CTD PMID:37748715 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EIF4EBP1 mRNA CTD PMID:37748715 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ELF1 mRNA CTD PMID:37748715 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EMC9 mRNA CTD PMID:37748715 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098 		JBrowse link
G Enpep glutamyl aminopeptidase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ENPEP mRNA CTD PMID:37748715 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EPB41L5 mRNA CTD PMID:37748715 NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360 		JBrowse link
G Exosc6 exosome component 6 increases expression ISO N(4)-hydroxycytidine results in increased expression of EXOSC6 mRNA CTD PMID:37748715 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Fam98a family with sequence similarity 98, member A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FAM98A mRNA CTD PMID:37748715 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742 		JBrowse link
G Fanca FA complementation group A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FANCA mRNA CTD PMID:37748715 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527 		JBrowse link
G Fbxl12 F-box and leucine-rich repeat protein 12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FBXL12 mRNA CTD PMID:37748715 NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FBXO5 mRNA CTD PMID:37748715 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fetub fetuin B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FETUB mRNA CTD PMID:37748715 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135 		JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FAM160B2 mRNA CTD PMID:37748715 NCBI chr15:45,656,641...45,674,603
Ensembl chr15:45,656,647...45,674,105 		JBrowse link
G Foxk2 forkhead box K2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FOXK2 mRNA CTD PMID:37748715 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563 		JBrowse link
G Fzd4 frizzled class receptor 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FZD4 mRNA CTD PMID:37748715 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GADD45A mRNA CTD PMID:37748715 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GARS mRNA CTD PMID:37748715 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609 		JBrowse link
G Gas2 growth arrest-specific 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GAS2 mRNA CTD PMID:37748715 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619 		JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GDF15 mRNA CTD PMID:37748715 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gid4 GID complex subunit 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GID4 mRNA CTD PMID:37748715 NCBI chr10:45,221,556...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621 		JBrowse link
G Glb1 galactosidase, beta 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GLB1 mRNA CTD PMID:37748715 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GPT2 mRNA CTD PMID:37748715 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO N(4)-hydroxycytidine results in increased expression of GRB10 mRNA CTD PMID:37748715 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grcc10 gene rich cluster, C10 gene decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GRCC10 mRNA CTD PMID:37748715 NCBI chr 4:157,551,276...157,552,924 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HADHA mRNA CTD PMID:37748715 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HADHB mRNA CTD PMID:37748715 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hax1 HCLS1 associated protein X-1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HAX1 mRNA CTD PMID:37748715 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714 		JBrowse link
G Helz helicase with zinc finger decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HELZ mRNA CTD PMID:37748715 NCBI chr10:92,479,403...92,645,234
Ensembl chr10:92,501,518...92,638,383 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions		 ISO N(4)-hydroxycytidine results in increased expression of HERPUD1 mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of HERPUD1 mRNA]		 CTD PMID:37748715 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Herpud2 HERPUD family member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HERPUD2 mRNA CTD PMID:37748715 NCBI chr 8:23,573,374...23,618,380
Ensembl chr 8:23,573,379...23,617,874 		JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HEXA mRNA CTD PMID:37748715 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HEXIM1 mRNA CTD PMID:37748715 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HMOX1 mRNA CTD PMID:37748715 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IARS mRNA CTD PMID:37748715 NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ID2 mRNA CTD PMID:37748715 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Inip INTS3 and NABP interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of INIP mRNA CTD PMID:37748715 NCBI chr 5:74,648,392...74,662,628
Ensembl chr 5:74,648,392...74,662,628 		JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IRAK1BP1 mRNA CTD PMID:37748715 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IRF2BP2 mRNA CTD PMID:37748715 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Jam3 junctional adhesion molecule 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of JAM3 mRNA CTD PMID:37748715 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of JDP2 mRNA CTD PMID:37748715 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485 		JBrowse link
G Lgals1 galectin 1 multiple interactions
decreases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in decreased expression of LGALS1 mRNA] CTD PMID:37748715 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lig1 DNA ligase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LIG1 mRNA CTD PMID:37748715 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LRFN1 mRNA CTD PMID:37748715 NCBI chr 1:83,742,442...83,761,450
Ensembl chr 1:83,682,964...83,761,449 		JBrowse link
G Lyrm7 LYR motif containing 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LYRM7 mRNA CTD PMID:37748715 NCBI chr10:38,964,299...38,983,628
Ensembl chr10:38,964,311...38,983,601 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MAP2K5 mRNA CTD PMID:37748715 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MAPRE3 mRNA CTD PMID:37748715 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MCAM mRNA CTD PMID:37748715 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MDH1 mRNA CTD PMID:37748715 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Midn midnolin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MIDN mRNA CTD PMID:37748715 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MKNK1 mRNA CTD PMID:37748715 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Mob4 MOB family member 4, phocein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MOB4 mRNA CTD PMID:37748715 NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329 		JBrowse link
G Mrps12 mitochondrial ribosomal protein S12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MRPS12 mRNA CTD PMID:37748715 NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780 		JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MRPS27 mRNA CTD PMID:37748715 NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MSMO1 mRNA CTD PMID:37748715 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mt2A metallothionein 2A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MT2 mRNA CTD PMID:37748715 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796 		JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr13:96,362,810...96,397,284 JBrowse link
G Mtbp MDM2 binding protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTBP mRNA CTD PMID:37748715 NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTHFD1L mRNA CTD PMID:37748715 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of MTHFD2 mRNA] CTD PMID:37748715 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTX1 mRNA CTD PMID:37748715 NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MYC mRNA CTD PMID:37748715 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nabp1 nucleic acid binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NABP1 mRNA CTD PMID:37748715 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107 		JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NARS mRNA CTD PMID:37748715 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622 		JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCAPD2 mRNA CTD PMID:37748715 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCAPG mRNA CTD PMID:37748715 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCOR1 mRNA CTD PMID:37748715 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PVRL1 mRNA CTD PMID:37748715 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NSF mRNA CTD PMID:37748715 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NSUN3 mRNA CTD PMID:37748715 NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543 		JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of WDYHV1 mRNA CTD PMID:37748715 NCBI chr 7:89,684,318...89,704,484
Ensembl chr 7:89,684,323...89,704,474 		JBrowse link
G Nup85 nucleoporin 85 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NUP85 mRNA CTD PMID:37748715 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of NUPR1 mRNA] CTD PMID:37748715 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Nxf7 nuclear RNA export factor 7 increases expression ISO N(4)-hydroxycytidine results in increased expression of NXF2 mRNA CTD PMID:37748715 NCBI chr  X:98,535,374...98,552,562
Ensembl chr  X:98,535,375...98,552,526 		JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OGDH mRNA CTD PMID:37748715 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Oip5 Opa interacting protein 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OIP5 mRNA CTD PMID:37748715 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250 		JBrowse link
G Optn optineurin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OPTN mRNA CTD PMID:37748715 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Osgepl1 O-sialoglycoprotein endopeptidase-like 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OSGEPL1 mRNA CTD PMID:37748715 NCBI chr 9:48,214,995...48,229,440
Ensembl chr 9:48,215,402...48,229,388 		JBrowse link
G P2rx3 purinergic receptor P2X 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of P2RX3 mRNA CTD PMID:37748715 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178 		JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO N(4)-hydroxycytidine results in increased expression of P2RX7 mRNA CTD PMID:37748715 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of P4HA2 mRNA CTD PMID:37748715 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PAK2 mRNA CTD PMID:37748715 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pde3a phosphodiesterase 3A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDE3A mRNA CTD PMID:37748715 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDE4DIP mRNA CTD PMID:37748715 NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379 		JBrowse link
G Pds5b PDS5 cohesin associated factor B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDS5B mRNA CTD PMID:37748715 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pex1 peroxisomal biogenesis factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PEX1 mRNA CTD PMID:37748715 NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PGAM2 mRNA CTD PMID:37748715 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PGP mRNA CTD PMID:37748715 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858 		JBrowse link
G Pmch pro-melanin-concentrating hormone decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PMCH mRNA CTD PMID:37748715 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Polr2a RNA polymerase II subunit A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of POLR2A mRNA CTD PMID:37748715 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PPP1R15A mRNA CTD PMID:37748715 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PPP1R3C mRNA CTD PMID:37748715 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PSAT1 mRNA CTD PMID:37748715 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Psph phosphoserine phosphatase increases expression ISO N(4)-hydroxycytidine results in increased expression of PSPH mRNA CTD PMID:37748715 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PTK2 mRNA CTD PMID:37748715 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rab21 RAB21, member RAS oncogene family decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RAB21 mRNA CTD PMID:37748715 NCBI chr 7:50,904,050...50,928,890
Ensembl chr 7:50,904,057...50,928,839 		JBrowse link
G Rabggta Rab geranylgeranyltransferase subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RABGGTA mRNA CTD PMID:37748715 NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348 		JBrowse link
G Rad54l RAD54 like decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RAD54L mRNA CTD PMID:37748715 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO N(4)-hydroxycytidine results in increased expression of REEP6 mRNA CTD PMID:37748715 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597 		JBrowse link
G Rfc2 replication factor C subunit 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RFC2 mRNA CTD PMID:37748715 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RHBDD1 mRNA CTD PMID:37748715 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Rragc Ras-related GTP binding C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RRAGC mRNA CTD PMID:37748715 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Rspry1 ring finger and SPRY domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RSPRY1 mRNA CTD PMID:37748715 NCBI chr19:10,352,449...10,403,015
Ensembl chr19:10,353,821...10,401,102 		JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SAMM50 mRNA CTD PMID:37748715 NCBI chr 7:115,317,472...115,341,682
Ensembl chr 7:115,317,404...115,341,682 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SARS mRNA CTD PMID:37748715 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Sema6a semaphorin 6A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SEMA6A mRNA CTD PMID:37748715 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954 		JBrowse link
G Sesn1 sestrin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SESN1 mRNA CTD PMID:37748715 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SESN2 mRNA CTD PMID:37748715 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SH3TC1 mRNA CTD PMID:37748715 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SHMT2 mRNA CTD PMID:37748715 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SKA2 mRNA CTD PMID:37748715 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO N(4)-hydroxycytidine results in increased expression of SLC1A4 mRNA CTD PMID:37748715 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC1A5 mRNA CTD PMID:37748715 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc25a31 solute carrier family 25 member 31 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A31 mRNA CTD PMID:37748715 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795 		JBrowse link
G Slc25a36 solute carrier family 25 member 36 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A36 mRNA CTD PMID:37748715 NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A4 mRNA CTD PMID:37748715 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC26A2 mRNA CTD PMID:37748715 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC2A1 mRNA CTD PMID:37748715 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc35a4 solute carrier family 35, member A4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC35A4 mRNA CTD PMID:37748715 NCBI chr18:28,280,483...28,284,610
Ensembl chr18:28,279,750...28,284,725 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A1 mRNA CTD PMID:37748715 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A2 mRNA CTD PMID:37748715 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc38a7 solute carrier family 38, member 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A7 mRNA CTD PMID:37748715 NCBI chr19:9,209,203...9,225,472
Ensembl chr19:9,209,257...9,225,454 		JBrowse link
G Slc39a4 solute carrier family 39 member 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC39A4 mRNA CTD PMID:37748715 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC3A2 mRNA CTD PMID:37748715 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc44a4 solute carrier family 44, member 4 multiple interactions
decreases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in decreased expression of SLC44A4 mRNA] CTD PMID:37748715 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC6A9 mRNA CTD PMID:37748715 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of SLC7A1 mRNA] CTD PMID:37748715 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression ISO N(4)-hydroxycytidine results in increased expression of SLC7A3 mRNA CTD PMID:37748715 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC7A5 mRNA CTD PMID:37748715 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slc7a7 solute carrier family 7 member 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC7A7 mRNA CTD PMID:37748715 NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648 		JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SMCR8 mRNA CTD PMID:37748715 NCBI chr10:45,457,962...45,465,101
Ensembl chr10:45,457,605...45,468,876 		JBrowse link
G Smim22 small integral membrane protein 22 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SMIM22 mRNA CTD PMID:37748715 NCBI chr10:10,572,146...10,574,339 JBrowse link
G Snord1c small nucleolar RNA, C/D box 1C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SNORD1C mRNA CTD PMID:37748715 NCBI chr10:101,905,797...101,905,872
Ensembl chr10:101,905,797...101,905,872 		JBrowse link
G Snx4 sorting nexin 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SNX4 mRNA CTD PMID:37748715 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Spag7 sperm associated antigen 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SPAG7 mRNA CTD PMID:37748715 NCBI chr10:55,377,249...55,383,404
Ensembl chr10:55,377,249...55,383,404 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SQLE mRNA CTD PMID:37748715 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srxn1 sulfiredoxin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SRXN1 mRNA CTD PMID:37748715 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Stc2 stanniocalcin 2 multiple interactions
increases expression		 ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of STC2 mRNA] CTD PMID:37748715 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stil STIL, centriolar assembly protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of STIL mRNA CTD PMID:37748715 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Stx7 syntaxin 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of STX7 mRNA CTD PMID:37748715 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Svil supervillin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SVIL mRNA CTD PMID:37748715 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404 		JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SYCP1 mRNA CTD PMID:37748715 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737 		JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TARS mRNA CTD PMID:37748715 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717 		JBrowse link
G Tas2r108 taste receptor, type 2, member 108 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TAS2R108 mRNA CTD PMID:37748715 NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:69,287,667...69,288,581 		JBrowse link
G Tat tyrosine aminotransferase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TAT mRNA CTD PMID:37748715 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tbcc tubulin folding cofactor C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TBCC mRNA CTD PMID:37748715 NCBI chr 9:14,098,855...14,100,043
Ensembl chr 9:14,098,868...14,100,042 		JBrowse link
G Tdg thymine-DNA glycosylase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TDG mRNA CTD PMID:37748715 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567 		JBrowse link
G Tec tec protein tyrosine kinase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TEC mRNA CTD PMID:37748715 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557 		JBrowse link
G Terf1 telomeric repeat binding factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TERF1 mRNA CTD PMID:37748715 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Thap4 THAP domain containing 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of THAP4 mRNA CTD PMID:37748715 NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306 		JBrowse link
G Tmppe transmembrane protein with metallophosphoesterase domain decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TMPPE mRNA CTD PMID:37748715 NCBI chr 8:114,085,497...114,093,388
Ensembl chr 8:114,084,831...114,094,286 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TOP2A mRNA CTD PMID:37748715 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tor1aip1 torsin 1A interacting protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TOR1AIP1 mRNA CTD PMID:37748715 NCBI chr13:68,196,681...68,226,121
Ensembl chr13:68,196,681...68,225,862 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRP53INP1 mRNA CTD PMID:37748715 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Tpcn2 two pore segment channel 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TPCN2 mRNA CTD PMID:37748715 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions		 ISO N(4)-hydroxycytidine results in increased expression of TRIB3 mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of TRIB3 mRNA]		 CTD PMID:37748715 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim32 tripartite motif-containing 32 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRIM32 mRNA CTD PMID:37748715 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Trip12 thyroid hormone receptor interactor 12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRIP12 mRNA CTD PMID:37748715 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403 		JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRPM6 mRNA CTD PMID:37748715 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TUBB5 mRNA CTD PMID:37748715 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tug1 taurine up-regulated 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TUG1 mRNA CTD PMID:37748715 NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927 		JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TXNIP mRNA CTD PMID:37748715 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of UGDH mRNA CTD PMID:37748715 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Vangl1 VANGL planar cell polarity protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VANGL1 mRNA CTD PMID:37748715 NCBI chr 2:189,586,681...189,637,609
Ensembl chr 2:189,589,229...189,637,619 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VEGFA mRNA CTD PMID:37748715 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VTCN1 mRNA CTD PMID:37748715 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YARS mRNA CTD PMID:37748715 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833 		JBrowse link
G Yipf2 Yip1 domain family, member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YIPF2 mRNA CTD PMID:37748715 NCBI chr 8:20,141,148...20,145,349
Ensembl chr 8:20,141,155...20,145,339 		JBrowse link
G Ypel5 yippee-like 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YPEL5 mRNA CTD PMID:37748715 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691 		JBrowse link
G Zfp516 zinc finger protein 516 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ZFP516 mRNA CTD PMID:37748715 NCBI chr18:76,286,453...76,386,526
Ensembl chr18:76,302,096...76,385,269 		JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ZSWIM5 mRNA CTD PMID:37748715 NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:130,343,034...130,463,784 		JBrowse link
stavudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Stavudine results in increased expression of ABCB1 mRNA CTD PMID:18310046 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Stavudine results in decreased expression of ADIPOQ protein
Stavudine results in decreased expression of ADIPOQ mRNA; Stavudine results in decreased expression of ADIPOQ protein		 CTD PMID:15865214 PMID:17503663 PMID:17668557 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Alb albumin affects binding ISO Stavudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP Stavudine results in decreased expression of ATP5F1E mRNA CTD PMID:18299183 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Stavudine results in decreased expression of BCL2 protein CTD PMID:9007205 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Stavudine results in increased expression of BCL2L1 mRNA CTD PMID:18299183 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO Stavudine results in increased cleavage of CASP3 protein CTD PMID:32278789 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Stavudine results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Stavudine affects the expression of CDKN1A protein CTD PMID:18389896 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects expression ISO Stavudine affects the expression of CDKN2A protein CTD PMID:18389896 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Stavudine results in decreased expression of CEBPA protein CTD PMID:15722030 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Stavudine results in increased expression of CEBPB mRNA CTD PMID:18299183 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Stavudine results in increased phosphorylation of CHEK1 protein CTD PMID:32278789 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Stavudine results in increased expression of CPT1A mRNA CTD PMID:14576092 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression		 ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA
Stavudine results in decreased expression of FASN protein		 CTD PMID:11741158 PMID:15722030 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP Stavudine results in increased expression of FTH1 mRNA CTD PMID:18299183 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Gan gigaxonin decreases expression ISO Stavudine results in decreased expression of GAN mRNA; Stavudine results in decreased expression of GAN protein CTD PMID:19398414 NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP Stavudine results in increased expression of GCLC mRNA CTD PMID:18299183 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression EXP Stavudine results in decreased expression of GPX4 mRNA CTD PMID:18299183 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP Stavudine results in increased expression of GSTA1 mRNA CTD PMID:18299183 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Stavudine results in increased expression of GSTP1 mRNA CTD PMID:18299183 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Stavudine affects the expression of HSPD1 protein CTD PMID:27041070 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Stavudine results in increased expression of IGFBP1 mRNA CTD PMID:18299183 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Stavudine results in increased expression of IL1B protein CTD PMID:17668557 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression ISO Stavudine results in increased expression of IL6 protein CTD PMID:17668557 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Stavudine results in increased expression of JUN mRNA CTD PMID:18299183 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Lep leptin decreases expression ISO Stavudine results in decreased expression of LEP protein CTD PMID:17668557 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial affects expression ISO Stavudine affects the expression of LONP1 protein CTD PMID:27041070 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA CTD PMID:11741158 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation ISO Stavudine results in decreased phosphorylation of MAPK8 protein CTD PMID:27041070 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression		 ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA
Stavudine results in increased expression of ME1 mRNA		 CTD PMID:11741158 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions
decreases expression		 EXP Carnitine inhibits the reaction [Stavudine results in decreased expression of MTTP mRNA] CTD PMID:18299183 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO Stavudine results in increased expression of NRF1 mRNA CTD PMID:17926646 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
decreases expression		 EXP
ISO		 Stavudine results in increased expression of PCNA mRNA
Stavudine results in decreased expression of PCNA protein		 CTD PMID:18299183 PMID:32278789 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Stavudine results in decreased expression of PPARG mRNA
Stavudine results in decreased expression of PPARG mRNA; Stavudine results in decreased expression of PPARG protein		 CTD PMID:14518702 PMID:15722030 PMID:17926646 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Stavudine results in decreased expression of PTGS2 protein CTD PMID:18389896 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sirt3 sirtuin 3 increases expression ISO Stavudine results in increased expression of SIRT3 protein CTD PMID:27041070 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir] CTD PMID:15951836 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 increases expression EXP Stavudine results in increased expression of SLC25A5 mRNA CTD PMID:18299183 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Stavudine CTD PMID:19164483 NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression EXP Stavudine results in decreased expression of STAT3 mRNA CTD PMID:18299183 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Stavudine results in decreased expression of TFAP2A mRNA CTD PMID:17926646 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Stavudine results in increased expression of TNF protein CTD PMID:17668557 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tymp thymidine phosphorylase increases expression ISO Stavudine results in increased expression of TYMP protein CTD PMID:16457948 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Ucp1 uncoupling protein 1 decreases expression
increases expression		 ISO Stavudine results in decreased expression of UCP1 mRNA
Stavudine results in increased expression of UCP1		 CTD PMID:16038477 PMID:17926646 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Stavudine results in decreased expression of UCP2 mRNA CTD PMID:14518702 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ucp3 uncoupling protein 3 decreases expression ISO Stavudine results in decreased expression of UCP3 mRNA CTD PMID:14518702 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
tenofovir disoproxil fumarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Tenofovir results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Acacb acetyl-CoA carboxylase beta affects expression ISO Tenofovir affects the expression of ACACB mRNA CTD PMID:20032539 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Tenofovir results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein] CTD PMID:36309141 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in decreased activity of CAT protein CTD PMID:34118364 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 ISO Tenofovir results in increased expression of CCL20 mRNA
Tenofovir results in increased expression of and results in increased secretion of CCL20 protein		 CTD PMID:24205323 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein
Tenofovir results in increased expression of CDKN1A protein		 CTD PMID:31545371 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Tenofovir results in decreased activity of CYP2E1 protein CTD PMID:17162464 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked increases expression EXP Tenofovir results in increased expression of DDX3Y mRNA CTD PMID:37852574 NCBI chr  Y:1,115,095...1,135,754
Ensembl chr  Y:1,116,309...1,135,706 		JBrowse link
G Edn1 endothelin 1 increases secretion
multiple interactions		 ISO Tenofovir results in increased secretion of EDN1 protein
coenzyme Q10 inhibits the reaction [Tenofovir results in increased secretion of EDN1 protein]		 CTD PMID:23640862 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha affects phosphorylation ISO Tenofovir affects the phosphorylation of EIF2S1 protein CTD PMID:27041070 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP Tenofovir results in decreased expression of FGB mRNA CTD PMID:37852574 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Gjc2 gap junction protein, gamma 2 increases expression EXP Tenofovir results in increased expression of GJC2 mRNA CTD PMID:37852574 NCBI chr10:43,962,642...43,971,358
Ensembl chr10:43,962,642...43,970,467 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion
multiple interactions		 ISO Tenofovir results in increased secretion of HAVCR1 protein
Tenofovir inhibits the reaction [cidofovir results in increased secretion of HAVCR1 protein]		 CTD PMID:29738843 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 affects expression ISO Tenofovir affects the expression of HSD11B1 mRNA CTD PMID:20032539 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Tenofovir affects the expression of HSPD1 protein CTD PMID:27041070 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein] CTD PMID:36309141 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Irf4 interferon regulatory factor 4 decreases expression EXP Tenofovir results in decreased expression of IRF4 mRNA CTD PMID:37852574 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Kdm5d lysine demethylase 5D increases expression EXP Tenofovir results in increased expression of KDM5D mRNA CTD PMID:37852574 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018 		JBrowse link
G Klf15 KLF transcription factor 15 decreases expression EXP Tenofovir results in decreased expression of KLF15 mRNA CTD PMID:37852574 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Lipe lipase E, hormone sensitive type affects expression ISO Tenofovir affects the expression of LIPE mRNA CTD PMID:20032539 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial affects expression ISO Tenofovir affects the expression of LONP1 protein CTD PMID:27041070 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Lpin1 lipin 1 decreases expression EXP Tenofovir results in decreased expression of LPIN1 mRNA CTD PMID:37852574 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 affects phosphorylation ISO Tenofovir affects the phosphorylation of MAPK8 protein CTD PMID:27041070 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of MPO protein CTD PMID:34118364 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO Tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA] CTD PMID:16940060 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP Tenofovir results in decreased expression of NFKBIA protein CTD PMID:27899301 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Tenofovir results in increased expression of NOS2 mRNA; Tenofovir results in increased expression of NOS2 protein CTD PMID:27899301 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation		 ISO coenzyme Q10 inhibits the reaction [Tenofovir results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Tenofovir affects the expression of NR3C1 mRNA CTD PMID:20032539 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Tenofovir results in increased expression of NT5E mRNA CTD PMID:24205323 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial decreases expression ISO Tenofovir results in decreased expression of NT5M mRNA CTD PMID:24205323 NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Tenofovir affects the expression of PPARG mRNA CTD PMID:20032539 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Tenofovir results in increased expression of PTGS2 mRNA; Tenofovir results in increased expression of PTGS2 protein CTD PMID:27899301 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
increases expression		 EXP Melatonin inhibits the reaction [Tenofovir affects the localization of RELA protein]; Melatonin inhibits the reaction [Tenofovir results in increased expression of and results in increased activity of RELA protein]; Melatonin inhibits the reaction [Tenofovir results in increased expression of RELA mRNA]; Tenofovir results in increased expression of and results in increased activity of RELA protein CTD PMID:27899301 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sirt3 sirtuin 3 increases expression ISO Tenofovir results in increased expression of SIRT3 protein CTD PMID:27041070 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases response to substance
increases import
multiple interactions		 ISO SLC22A6 protein results in increased susceptibility to Tenofovir
SLC22A6 protein results in increased import of Tenofovir
Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to Tenofovir]; SLC22A6 protein results in increased uptake of and results in increased susceptibility to Tenofovir; Tenofovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]		 CTD PMID:23856525 PMID:25448811 PMID:29738843 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance
increases import		 ISO SLC22A8 protein results in increased susceptibility to Tenofovir
SLC22A8 protein results in increased import of Tenofovir		 CTD PMID:25448811 PMID:29738843 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
increases expression		 ISO
EXP		 Tenofovir results in decreased expression of TNF mRNA
[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein]
Tenofovir results in increased expression of TNF mRNA; Tenofovir results in increased expression of TNF protein		 CTD PMID:24205323 PMID:27899301 PMID:36309141 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein
Tenofovir results in increased expression of TP53 protein		 CTD PMID:31545371 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression EXP Tenofovir results in increased expression of USP18 mRNA CTD PMID:37852574 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
triciribine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO triciribine results in decreased phosphorylation of AKT1 protein CTD PMID:20857426 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases phosphorylation ISO triciribine results in decreased phosphorylation of AKT2 protein CTD PMID:20857426 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO triciribine inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Nitroprusside affects the localization of BAX protein]] CTD PMID:22178905 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA]
triciribine results in increased expression of CASP3 mRNA		 CTD PMID:29117515 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO triciribine inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA] CTD PMID:19961161 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases activity ISO triciribine results in decreased activity of FSHB protein CTD PMID:23254195 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO triciribine results in increased expression of H2AX mRNA CTD PMID:29117515 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO triciribine inhibits the reaction [HRAS protein results in increased activity of MMP2 protein] CTD PMID:23877152 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO triciribine inhibits the reaction [INS protein results in decreased susceptibility to sodium arsenite] CTD PMID:25982963 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO triciribine inhibits the reaction [HRAS protein results in increased activity of MMP2 protein] CTD PMID:23877152 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP triciribine inhibits the reaction [Mevinphos results in increased expression of NOS2 protein] CTD PMID:24462917 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression		 ISO triciribine inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]; triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA]
triciribine results in increased expression of PARP1 mRNA		 CTD PMID:29117515 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Phb1 prohibitin 1 increases expression EXP triciribine results in increased expression of PHB1 protein CTD PMID:23254195 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP triciribine inhibits the reaction [Mevinphos results in increased activity of RELA protein] CTD PMID:24462917 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
trifluridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO CA 074 methyl ester inhibits the reaction [Trifluridine results in increased cleavage of CASP3 protein]; Trifluridine results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:19816940 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO Trifluridine results in increased cleavage of CASP8 protein CTD PMID:19816940 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO Trifluridine results in increased cleavage of CASP9 protein CTD PMID:19816940 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ctsb cathepsin B increases cleavage
multiple interactions		 ISO Trifluridine results in increased cleavage of CTSB protein
CA 074 methyl ester inhibits the reaction [Trifluridine results in increased cleavage of CTSB protein]		 CTD PMID:19816940 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Trifluridine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Trifluridine inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:30818834 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO Trifluridine inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Trifluridine results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO Trifluridine results in increased activity of NR1I2 protein
[Trifluridine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Trifluridine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Trifluridine results in increased cleavage of PARP1 protein CTD PMID:19816940 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Trifluridine affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          nitrogen atom 18933
            nitrogen molecular entity 18933
              organonitrogen compound 18783
                N-glycosyl compound 5806
                  nucleoside analogue 954
                    (-)-neplanocin a 0
                    2'-deoxy-5,6-dihydroxy-5,6-dihydrocytidine 0
                    2'-deoxycytidine dimer 0
                    2'-deoxycytidine-thymidine dimer 0
                    2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                    2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine + 0
                    2-thio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                    2-thiouridine 0
                    4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylcytosine 0
                    4-demethylwyosine 0
                    4-thiouridine 0
                    5-aminomethyl-2-thiouridine + 0
                    5-azacytidine 406
                    5-carboxy-2'-deoxyuridine 0
                    5-ethynylcytidine 0
                    6-azathymidine 0
                    9-(tetrahydrofuryl)adenine 3
                    9-ribosyl-trans-zeatin 0
                    ApU 0
                    Aristeromycin 0
                    CpA 0
                    GpA 0
                    GpG 0
                    GpU 0
                    LSM-6701 0
                    N(4)-hydroxycytidine + 235
                    N(6)-(Delta(2)-isopentenyl)adenosine + 0
                    N(6)-carbamoylmethyl-2'-deoxyadenosine 0
                    Neplanocin A 0
                    UpA 0
                    UpG 0
                    acadesine + 136
                    allopurinol riboside 0
                    alpha-N-(9-beta-D-ribofuranosylpurin-6-yl)glycinamide 0
                    dApdA 0
                    dApdC 0
                    dApdG 0
                    dApdT 0
                    dCpdA 0
                    dGpdA 0
                    dGpdC 0
                    dGpdG 0
                    dGpdT 0
                    dTpdA 0
                    dTpdG 0
                    emtricitabine + 5
                    favipiravir-RTP 0
                    fazarabine 0
                    floxuridine 16
                    flucytosine 3
                    fludarabine phosphate 0
                    jawsamycin 0
                    lamivudine 214
                    molnupiravir 0
                    oxetanocin A + 0
                    sangivamycic acid 0
                    sangivamycin 0
                    sapacitabine 0
                    stavudine 49
                    tenofovir (anhydrous) + 42
                    thymidine dimer 0
                    triciribine 14
                    trifluridine + 12
                    wybutosine 0
                    wybutoxosine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbohydrates and carbohydrate derivatives 15270
                                    carbohydrate 15270
                                      carbohydrate derivative 14278
                                        glycosyl compound 13035
                                          N-glycosyl compound 5806
                                            nucleoside analogue 954
                                              (-)-neplanocin a 0
                                              2'-deoxy-5,6-dihydroxy-5,6-dihydrocytidine 0
                                              2'-deoxycytidine dimer 0
                                              2'-deoxycytidine-thymidine dimer 0
                                              2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                              2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine + 0
                                              2-thio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                              2-thiouridine 0
                                              4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylcytosine 0
                                              4-demethylwyosine 0
                                              4-thiouridine 0
                                              5-aminomethyl-2-thiouridine + 0
                                              5-azacytidine 406
                                              5-carboxy-2'-deoxyuridine 0
                                              5-ethynylcytidine 0
                                              6-azathymidine 0
                                              9-(tetrahydrofuryl)adenine 3
                                              9-ribosyl-trans-zeatin 0
                                              ApU 0
                                              Aristeromycin 0
                                              CpA 0
                                              GpA 0
                                              GpG 0
                                              GpU 0
                                              LSM-6701 0
                                              N(4)-hydroxycytidine + 235
                                              N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                              N(6)-carbamoylmethyl-2'-deoxyadenosine 0
                                              Neplanocin A 0
                                              UpA 0
                                              UpG 0
                                              acadesine + 136
                                              allopurinol riboside 0
                                              alpha-N-(9-beta-D-ribofuranosylpurin-6-yl)glycinamide 0
                                              dApdA 0
                                              dApdC 0
                                              dApdG 0
                                              dApdT 0
                                              dCpdA 0
                                              dGpdA 0
                                              dGpdC 0
                                              dGpdG 0
                                              dGpdT 0
                                              dTpdA 0
                                              dTpdG 0
                                              emtricitabine + 5
                                              favipiravir-RTP 0
                                              fazarabine 0
                                              floxuridine 16
                                              flucytosine 3
                                              fludarabine phosphate 0
                                              jawsamycin 0
                                              lamivudine 214
                                              molnupiravir 0
                                              oxetanocin A + 0
                                              sangivamycic acid 0
                                              sangivamycin 0
                                              sapacitabine 0
                                              stavudine 49
                                              tenofovir (anhydrous) + 42
                                              thymidine dimer 0
                                              triciribine 14
                                              trifluridine + 12
                                              wybutosine 0
                                              wybutoxosine 0
paths to the root