Gene: Chek2 (checkpoint kinase 2) Rattus norvegicus
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Symbol: Chek2
Name: checkpoint kinase 2
Description: ENCODES a protein that exhibits kinase activity; protein kinase activity; protein serine/threonine kinase activity; INVOLVED IN cellular response to bisphenol A; cellular response to drug; DNA damage checkpoint; PARTICIPATES IN p53 signaling pathway; cell cycle pathway, mitotic; ASSOCIATED WITH Kidney Neoplasms; Metabolic Syndrome X; Urinary Bladder Neoplasms; FOUND IN nucleus; chromosome, telomeric region (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Chk2; CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); protein kinase Chk2; Rad53; serine/threonine-protein kinase Chk2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01251,845,574 - 51,878,098 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01253,583,932 - 53,616,450 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41245,933,900 - 45,965,427 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11245,797,764 - 45,829,292 (-)NCBI
Celera1247,348,969 - 47,380,486 (-)NCBI
Cytogenetic Map12q16NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chek2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 621543
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-20
Status: ACTIVE