| (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:736090 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EDNRB mRNA | CTD | PMID:22079256 |
| (R)-noradrenaline | multiple interactions | EXP | | 6480464 | [EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine; more ... | CTD | PMID:16023617 |
| (S)-colchicine | increases expression | EXP | | 6480464 | Colchicine results in increased expression of EDNRB mRNA | CTD | PMID:20624997 |
| (S)-nicotine | increases activity | EXP | | 6480464 | Nicotine results in increased activity of EDNRB protein | CTD | PMID:21316381 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:736090 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EDNRB mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:736090 | 6480464 | Tetrachlorodibenzodioxin affects the expression of EDNRB mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10505 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of EDNRB mRNA | CTD | PMID:19465110 |
| 2-butoxyethanol | increases expression | ISO | RGD:10505 | 6480464 | n-butoxyethanol results in increased expression of EDNRB mRNA | CTD | PMID:19812364 |
| 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | multiple interactions | EXP | | 6480464 | Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] | CTD | PMID:7756592 |
| 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | increases expression | EXP | | 6480464 | Puromycin Aminonucleoside results in increased expression of EDNRB mRNA | CTD | PMID:7756592 |
| 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of EDNRB mRNA | CTD | PMID:19162173 |
| 6alpha-methylprednisolone | multiple interactions | EXP | | 6480464 | Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] | CTD | PMID:7756592 |
| 8-bromo-3',5'-cyclic GMP | multiple interactions | EXP | | 6480464 | 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; more ... | CTD | PMID:16023617 |
| acetylsalicylic acid | multiple interactions | ISO | RGD:736090 | 6480464 | Aspirin inhibits the reaction [IL1B results in increased activity of EDNRB] | CTD | PMID:12126971 |
| actinomycin D | multiple interactions | EXP | | 6480464 | Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; more ... | CTD | PMID:20561571 |
| actinomycin D | multiple interactions | EXP | | 6480464 | Dactinomycin inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA] | CTD | PMID:22207076 |
| actinomycin D | multiple interactions | EXP | | 6480464 | Dactinomycin inhibits the reaction [Smoke analog results in increased expression of EDNRB protein] | CTD | PMID:20716444 |
| all-trans-retinoic acid | decreases expression | ISO | RGD:736090 | 6480464 | Tretinoin results in decreased expression of EDNRB mRNA | CTD | PMID:21934132 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of EDNRB mRNA | CTD | PMID:16483693 |
| amphotericin B | increases expression | ISO | RGD:736090 | 6480464 | Amphotericin B results in increased expression of EDNRB mRNA | CTD | PMID:20849824 |
| angiotensin II | increases expression | EXP | | 6480464 | Angiotensin II results in increased expression of EDNRB protein | CTD | PMID:15007106 |
| arsenic atom | decreases expression | ISO | RGD:10505 | 6480464 | Arsenic results in decreased expression of EDNRB mRNA | CTD | PMID:19654921 |
| benzo[a]pyrene | increases expression | ISO | RGD:10505 | 6480464 | Benzo(a)pyrene results in increased expression of EDNRB mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | increases expression | ISO | RGD:10505 | 6480464 | Benzo(a)pyrene results in increased expression of EDNRB mRNA | CTD | PMID:19770486 PMID:21964900 |
| benzo[a]pyrene | decreases expression | ISO | RGD:10505 | 6480464 | Benzo(a)pyrene results in decreased expression of EDNRB mRNA | CTD | PMID:22228805 PMID:22610609 |
| benzo[a]pyrene | decreases expression | ISO | RGD:10505 | 6480464 | Benzo(a)pyrene results in decreased expression of EDNRB mRNA | CTD | PMID:22228805 |
| bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of EDNRB mRNA | CTD | PMID:20920545 |
| bosentan | multiple interactions | ISO | RGD:736090 | 6480464 | bosentan binds to and results in decreased activity of EDNRB protein | CTD | PMID:16219361 |
| calcitriol | increases expression | ISO | RGD:10505 | 6480464 | Calcitriol results in increased expression of EDNRB mRNA | CTD | PMID:12230499 |
| chlorambucil | increases mutagenesis | ISO | RGD:10505 | 6480464 | Chlorambucil results in increased mutagenesis of EDNRB gene | CTD | PMID:10517996 |
| chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of EDNRB mRNA | CTD | PMID:23125180 |
| chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of EDNRB mRNA | CTD | PMID:20691718 |
| choline | multiple interactions | ISO | RGD:10505 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA | CTD | PMID:20938992 |
| chromium atom | multiple interactions | ISO | RGD:10505 | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of EDNRB mRNA] | CTD | PMID:16940432 |
| cisplatin | increases expression | ISO | RGD:736090 | 6480464 | Cisplatin results in increased expression of EDNRB mRNA | CTD | PMID:20849824 |
| cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of EDNRB mRNA | CTD | PMID:20187946 |
| cycloheximide | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; more ... | CTD | PMID:20561571 |
| cycloheximide | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [Smoke analog results in increased expression of EDNRB protein] | CTD | PMID:20716444 |
| cyclophosphamide | increases expression | ISO | RGD:736090 | 6480464 | Cyclophosphamide results in increased expression of EDNRB mRNA | CTD | PMID:20849824 |
| daunorubicin | increases expression | EXP | | 6480464 | Daunorubicin results in increased expression of EDNRB protein | CTD | PMID:20888384 |
| daunorubicin | multiple interactions | EXP | | 6480464 | telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] | CTD | PMID:20888384 |
| dexamethasone | multiple interactions | EXP | | 6480464 | Dexamethasone promotes the reaction [nitrofen results in increased expression of EDNRB mRNA] | CTD | PMID:10693666 |
| diarsenic trioxide | increases expression | ISO | RGD:736090 | 6480464 | arsenic trioxide results in increased expression of EDNRB mRNA alternative form | CTD | PMID:19128835 |
| diazoxide | multiple interactions | EXP | | 6480464 | CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA] | CTD | PMID:18594475 |
| diazoxide | increases expression | EXP | | 6480464 | Isoproterenol results in increased expression of EDNRB mRNA | CTD | PMID:18594475 |
| dibutyl phthalate | increases expression | ISO | RGD:10505 | 6480464 | Dibutyl Phthalate results in increased expression of EDNRB mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | increases expression | ISO | RGD:10505 | 6480464 | Dibutyl Phthalate results in increased expression of EDNRB mRNA | CTD | PMID:17361019 PMID:21266533 |
| dimethyl sulfoxide | increases expression | EXP | | 6480464 | Dimethyl Sulfoxide results in increased expression of EDNRB protein; more ... | CTD | PMID:20561571 |
| dimethyl sulfoxide | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; more ... | CTD | PMID:20561571 |
| dioxygen | increases expression | ISO | RGD:10505 | 6480464 | Oxygen deficiency results in increased expression of EDNRB mRNA; more ... | CTD | PMID:21926265 |
| dioxygen | multiple interactions | ISO | RGD:10505 | 6480464 | rosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRB mRNA]; more ... | CTD | PMID:21926265 |
| ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of EDNRB protein | CTD | PMID:16651399 |
| fenoterol | increases expression | ISO | RGD:736090 | 6480464 | Fenoterol results in increased expression of EDNRB mRNA | CTD | PMID:16340002 |
| folic acid | multiple interactions | ISO | RGD:10505 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA | CTD | PMID:20938992 |
| gefitinib | multiple interactions | ISO | RGD:10505 | 6480464 | gefitinib inhibits the reaction [TGFA protein results in decreased expression of EDNRB mRNA] | CTD | PMID:18424623 |
| Ile(5)-angiotensin II | increases expression | EXP | | 6480464 | Angiotensin II results in increased expression of EDNRB protein | CTD | PMID:15007106 |
| indomethacin | multiple interactions | ISO | RGD:736090 | 6480464 | Indomethacin inhibits the reaction [IL1B results in increased activity of EDNRB] | CTD | PMID:12126971 |
| isoprenaline | multiple interactions | EXP | | 6480464 | CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA] | CTD | PMID:18594475 |
| isoprenaline | increases expression | EXP | | 6480464 | Isoproterenol results in increased expression of EDNRB mRNA | CTD | PMID:18594475 |
| L-ascorbic acid | increases expression | ISO | RGD:10505 | 6480464 | Ascorbic Acid results in increased expression of EDNRB mRNA | CTD | PMID:15305145 |
| L-methionine | multiple interactions | ISO | RGD:10505 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA | CTD | PMID:20938992 |
| methotrexate | affects expression | ISO | RGD:10505 | 6480464 | Methotrexate affects the expression of EDNRB mRNA | CTD | PMID:18502557 |
| mifepristone | increases expression | ISO | RGD:736090 | 6480464 | Mifepristone results in increased expression of EDNRB mRNA | CTD | PMID:17584828 |
| N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:10505 | 6480464 | Ethylnitrosourea results in increased mutagenesis of EDNRB gene | CTD | PMID:17174358 PMID:9475716 |
| N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:10505 | 6480464 | Ethylnitrosourea results in increased mutagenesis of EDNRB gene | CTD | PMID:9475716 PMID:17174358 |
| N-methyl-N-nitrosurea | increases mutagenesis | ISO | RGD:10505 | 6480464 | Methylnitrosourea results in increased mutagenesis of EDNRB gene | CTD | PMID:17174358 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of EDNRB mRNA | CTD | PMID:19638242 |
| nicotinic acid | multiple interactions | ISO | RGD:10505 | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of EDNRB mRNA] | CTD | PMID:16940432 |
| nimesulide | multiple interactions | ISO | RGD:736090 | 6480464 | nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB] | CTD | PMID:12126971 |
| nitric oxide | multiple interactions | EXP | | 6480464 | [EDN1 protein results in increased activity of EDNRB protein] which results in increased abundance of Nitric Oxide | CTD | PMID:16380457 |
| nitroprusside | multiple interactions | EXP | | 6480464 | Nitroprusside inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; more ... | CTD | PMID:16023617 |
| ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of EDNRB mRNA | CTD | PMID:16081523 |
| ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of EDNRB mRNA | CTD | PMID:20980218 PMID:16081523 |
| ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of EDNRB mRNA | CTD | PMID:16081523 PMID:20980218 |
| ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Vehicle Emissions] results in increased expression of EDNRB mRNA | CTD | PMID:20980218 |
| paracetamol | affects expression | ISO | RGD:10505 | 6480464 | Acetaminophen affects the expression of EDNRB mRNA | CTD | PMID:17562736 |
| paracetamol | increases expression | ISO | RGD:736090 | 6480464 | Acetaminophen results in increased expression of EDNRB mRNA | CTD | PMID:21420995 |
| paricalcitol | multiple interactions | ISO | RGD:736090 | 6480464 | [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA | CTD | PMID:17715259 |
| phenobarbital | affects expression | ISO | RGD:10505 | 6480464 | Phenobarbital affects the expression of EDNRB mRNA | CTD | PMID:23091169 |
| phenylephrine | increases expression | EXP | | 6480464 | Phenylephrine results in increased expression of EDNRB protein | CTD | PMID:15007106 |
| phosphorus atom | multiple interactions | ISO | RGD:736090 | 6480464 | [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA | CTD | PMID:17715259 |
| phosphorus(.) | multiple interactions | ISO | RGD:736090 | 6480464 | [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA | CTD | PMID:17715259 |
| potassium chloride | multiple interactions | EXP | | 6480464 | atrasentan inhibits the reaction [[19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] | CTD | PMID:18823320 |
| quercetin | increases expression | ISO | RGD:736090 | 6480464 | Quercetin results in increased expression of EDNRB mRNA | CTD | PMID:15309432 |
| quercetin | affects expression | EXP | | 6480464 | Quercetin affects the expression of EDNRB mRNA | CTD | PMID:18178720 |
| rosiglitazone | increases expression | ISO | RGD:736090 | 6480464 | rosiglitazone results in increased expression of EDNRB mRNA; more ... | CTD | PMID:20516393 |
| rosiglitazone | multiple interactions | ISO | RGD:10505 | 6480464 | rosiglitazone promotes the reaction [[PPARG protein binds to EDNRB promoter] which results in increased expression of EDNRB mRNA] | CTD | PMID:20516393 PMID:20516393 |
| rosiglitazone | increases expression | EXP | | 6480464 | rosiglitazone results in increased expression of EDNRB mRNA | CTD | PMID:21172411 |
| rosiglitazone | multiple interactions | ISO | RGD:10505 | 6480464 | rosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRB protein]; more ... | CTD | PMID:21926265 |
| rosiglitazone | increases expression | ISO | RGD:10505 | 6480464 | rosiglitazone results in increased expression of EDNRB mRNA; more ... | CTD | PMID:20516393 |
| rosiglitazone | multiple interactions | ISO | RGD:10505 | 6480464 | rosiglitazone promotes the reaction [[PPARG protein binds to EDNRB promoter] which results in increased expression of EDNRB mRNA] | CTD | PMID:20516393 |
| sodium chloride | multiple interactions | EXP | | 6480464 | [19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA; more ... | CTD | PMID:18823320 |
| staurosporine | multiple interactions | EXP | | 6480464 | Staurosporine inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein]; more ... | CTD | PMID:20561571 |
| telmisartan | multiple interactions | EXP | | 6480464 | telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] | CTD | PMID:20888384 |
| testosterone | affects expression | EXP | | 6480464 | Testosterone affects the expression of EDNRB mRNA | CTD | PMID:14616470 PMID:12122504 |
| testosterone | affects expression | EXP | | 6480464 | Testosterone affects the expression of EDNRB mRNA | CTD | PMID:12122504 PMID:14616470 |
| testosterone enanthate | affects expression | ISO | RGD:736090 | 6480464 | testosterone enanthate affects the expression of EDNRB mRNA | CTD | PMID:17440010 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of EDNRB mRNA | CTD | PMID:16239168 PMID:12873816 |
| tetrachloromethane | multiple interactions | EXP | | 6480464 | EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]] | CTD | PMID:18205269 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of EDNRB protein | CTD | PMID:12708965 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of EDNRB mRNA | CTD | PMID:12873816 PMID:16239168 |
| tetrachloromethane | increases activity | EXP | | 6480464 | Carbon Tetrachloride results in increased activity of EDNRB protein | CTD | PMID:12873816 |
| tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of EDNRB mRNA | CTD | PMID:16644059 |
| tetrachloromethane | decreases expression | ISO | RGD:10505 | 6480464 | Carbon Tetrachloride results in decreased expression of EDNRB mRNA | CTD | PMID:17484886 |
| urethane | multiple interactions | ISO | RGD:10505 | 6480464 | Freund's Adjuvant inhibits the reaction [Urethane results in decreased expression of EDNRB mRNA]; more ... | CTD | PMID:12810352 |
| urethane | decreases expression | ISO | RGD:10505 | 6480464 | Urethane results in decreased expression of EDNRB mRNA | CTD | PMID:12810352 |
| valproic acid | increases expression | ISO | RGD:736090 | 6480464 | Valproic Acid results in increased expression of EDNRB mRNA | CTD | PMID:19101580 |
| vincaleukoblastine | increases expression | EXP | | 6480464 | Vinblastine results in increased expression of EDNRB mRNA | CTD | PMID:20624997 |
| vincristine | increases expression | EXP | | 6480464 | Vincristine results in increased expression of EDNRB mRNA | CTD | PMID:20624997 |
| wedelolactone | multiple interactions | EXP | | 6480464 | wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; more ... | CTD | PMID:20561571 |
| wedelolactone | multiple interactions | EXP | | 6480464 | wedelolactone inhibits the reaction [TNF protein results in increased expression of EDNRB protein]; more ... | CTD | PMID:22207076 |
| wedelolactone | multiple interactions | EXP | | 6480464 | wedelolactone inhibits the reaction [Smoke results in increased expression of EDNRB protein] | CTD | PMID:18718921 |
| zinc atom | decreases expression | EXP | | 6480464 | Zinc results in decreased expression of EDNRB mRNA | CTD | PMID:17074742 |
| zinc sulfate | decreases expression | EXP | | 6480464 | Zinc Sulfate results in decreased expression of EDNRB mRNA | CTD | PMID:17074742 |
| zinc(0) | decreases expression | EXP | | 6480464 | Zinc results in decreased expression of EDNRB mRNA | CTD | PMID:17074742 |