Gene: Prkaa2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)  Rattus norvegicus

Symbol: Prkaa2
Name: protein kinase, AMP-activated, alpha 2 catalytic subunit
Description: ENCODES a protein that exhibits AMP-activated protein kinase activity; ATP binding; protein binding, bridging; INVOLVED IN cellular response to organic nitrogen; fatty acid homeostasis; positive regulation of glycolysis; PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; vascular endothelial growth factor signaling pathway; autophagy pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2 (ortholog); Glucose Intolerance (ortholog); Insulin Resistance (ortholog); FOUND IN AMP-activated protein kinase complex; apical plasma membrane; cytoplasm; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5'-AMP-activated protein kinase catalytic subunit alpha-2; ACACA kinase; acetyl-CoA carboxylase kinase; AMP-activated protein kinase; AMPK; Ampk; AMPK alpha-2 chain; AMPK subunit alpha-2; Ampka2; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 2 catalytic subunit
Orthologs: Homo sapiens : PRKAA2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)  HGNC
Mus musculus : Prkaa2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q34 NCBI
RGSC Genome Assembly v5.05128,436,023 - 128,503,874-NCBI
RGSC Genome Assembly v3.45126,007,672 - 126,074,012-NCBI
Rat Celera Assembly5118,363,351 - 118,429,630-NCBI
Genome Assembly 3.15126,012,897 - 126,079,238-NCBI
RH 3.45688.6 RGD
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkaa2
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RGD Object Information
RGD ID: 620893
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2013-04-23
Status: ACTIVE