Gene: Prkaa2 (protein kinase AMP-activated catalytic subunit alpha 2) Rattus norvegicus
Symbol: Prkaa2
Name: protein kinase AMP-activated catalytic subunit alpha 2
Description: ENCODES a protein that exhibits AMP-activated protein kinase activity; ATP binding; protein binding, bridging; INVOLVED IN cellular response to organonitrogen compound; fatty acid homeostasis; positive regulation of glycolytic process; PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; vascular endothelial growth factor signaling pathway; autophagy pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2 (ortholog); Glucose Intolerance (ortholog); Insulin Resistance (ortholog); FOUND IN apical plasma membrane; cytoplasm; nucleotide-activated protein kinase complex; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
Also known as: 5'-AMP-activated protein kinase catalytic subunit alpha-2; ACACA kinase; acetyl-CoA carboxylase kinase; AMP-activated protein kinase; AMPK; AMPK alpha-2 chain; AMPK subunit alpha-2; Ampka2; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 2 catalytic subunit
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05124,568,845 - 124,642,569 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05128,436,023 - 128,503,874 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.45126,007,672 - 126,074,012 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15126,012,897 - 126,079,238 (-)NCBI
Celera5118,363,351 - 118,429,630 (-)NCBI
Cytogenetic Map5q34NCBImapview
RH 3.4 Map5688.6RGD

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkaa2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 620893
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-20
Status: ACTIVE