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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | increases expression | ISO | RGD:1312720 | 6480464 | Estradiol results in increased expression of STIL mRNA | CTD | PMID:20106945 | 17beta-estradiol | increases expression | ISO | RGD:1312720 | 6480464 | Estradiol results in increased expression of STIL mRNA | CTD | PMID:19167446 PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1312720 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of STIL mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1312720 | 6480464 | Tetrachlorodibenzodioxin affects the expression of STIL mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1312720 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of STIL mRNA | CTD | PMID:20106945 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1312720 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of STIL mRNA | CTD | PMID:20106945 PMID:21802500 | aflatoxin B1 | affects expression | ISO | RGD:1312720 | 6480464 | Aflatoxin B1 affects the expression of STIL protein | CTD | PMID:20106945 | benzo[a]pyrene | decreases expression | ISO | RGD:1312720 | 6480464 | Benzo(a)pyrene results in decreased expression of STIL mRNA | CTD | PMID:21802500 | calcitriol | decreases expression | ISO | RGD:1312720 | 6480464 | Calcitriol results in decreased expression of STIL mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | RGD:1312720 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of STIL mRNA | CTD | PMID:21592394 | chloroprene | increases expression | ISO | RGD:1312721 | 6480464 | Chloroprene results in increased expression of STIL mRNA | CTD | PMID:23125180 | coumestrol | multiple interactions | ISO | RGD:1312720 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of STIL mRNA; more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | RGD:1312720 | 6480464 | Coumestrol results in increased expression of STIL mRNA | CTD | PMID:19167446 | cyclosporin A | decreases expression | ISO | RGD:1312720 | 6480464 | Cyclosporine results in decreased expression of STIL mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | RGD:1312720 | 6480464 | Cyclosporine results in decreased expression of STIL mRNA | CTD | PMID:20106945 PMID:21632981 | dasatinib (anhydrous) | decreases expression | ISO | RGD:1312720 | 6480464 | dasatinib results in decreased expression of STIL mRNA | CTD | PMID:20579391 | formaldehyde | decreases expression | ISO | RGD:1312720 | 6480464 | Formaldehyde results in decreased expression of STIL mRNA | CTD | PMID:20655997 | paracetamol | increases expression | ISO | RGD:1312720 | 6480464 | Acetaminophen results in increased expression of STIL mRNA | CTD | PMID:22230336 | pirinixic acid | decreases expression | ISO | RGD:1312721 | 6480464 | pirinixic acid results in decreased expression of STIL mRNA | CTD | PMID:20813756 | pirinixic acid | multiple interactions | ISO | RGD:1312721 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of STIL mRNA] | CTD | PMID:20059764 | pirinixic acid | multiple interactions | ISO | RGD:1312721 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of STIL mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | ISO | RGD:1312721 | 6480464 | pirinixic acid results in increased expression of STIL mRNA | CTD | PMID:20059764 | quercetin | decreases expression | ISO | RGD:1312720 | 6480464 | Quercetin results in decreased expression of STIL mRNA | CTD | PMID:21632981 | quinolin-8-ol | decreases expression | ISO | RGD:1312720 | 6480464 | Oxyquinoline results in decreased expression of STIL mRNA | CTD | PMID:21632981 | resveratrol | decreases expression | ISO | RGD:1312720 | 6480464 | resveratrol results in decreased expression of STIL mRNA | CTD | PMID:15767336 | resveratrol | multiple interactions | ISO | RGD:1312720 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of STIL mRNA | CTD | PMID:19167446 | testosterone | multiple interactions | ISO | RGD:1312720 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of STIL mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | RGD:1312720 | 6480464 | Testosterone results in decreased expression of STIL mRNA | CTD | PMID:21592394 | trans-resveratrol | decreases expression | ISO | RGD:1312720 | 6480464 | resveratrol results in decreased expression of STIL mRNA | CTD | PMID:15767336 | trans-resveratrol | multiple interactions | ISO | RGD:1312720 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of STIL mRNA | CTD | PMID:19167446 | trimellitic anhydride | increases expression | ISO | RGD:1312721 | 6480464 | trimellitic anhydride results in increased expression of STIL mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | RGD:1312720 | 6480464 | troglitazone results in decreased expression of STIL mRNA | CTD | PMID:19140230 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations| External Database Links | |
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family (PID:200168) |
Disease Annotations
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family (PID:200168) |
References - curated| 1. |
GOA data from the GO Consortium |
| 2. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 3. |
RGD automated import pipeline for gene-chemical interactions |
| 4. |
RGD Automated Pipelines |
| 5. |
RGD comprehensive gene curation |
RGD Disease Portals| Stil has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Stil (Rattus norvegicus) |
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| STIL (Homo sapiens) |
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| Stil (Mus musculus) |
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Position Markers| AW535880 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | XM_001069563 | (Get FASTA) | Search GEO for Microarray Profiles |
| XM_233429 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR06039471 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01039265 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01039266 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01039267 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01039268 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | XM_001069563 | ||||||||||
| RefSeq Status: | |||||||||||
| Type: | CODING | ||||||||||
| Protein Acc Id: | XP_001069563 | ||||||||||
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| RefSeq Acc Id: | XM_233429 | |||||||||||||||
| RefSeq Status: | ||||||||||||||||
| Type: | CODING | |||||||||||||||
| Protein Acc Id: | XP_233429 | |||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | XP_001069563 | (Get FASTA) |
| XP_233429 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000007858 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000010410 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000010410 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 313506 | ENTREZGENE |
| HomoloGene Group ID | 2283 | ENTREZGENE |
| InterPro | Sil | UniProtKB/TrEMBL |
| IPI | IPI00358995 | UniProtKB/TrEMBL |
| KEGG Report | rno:313506 | ENTREZGENE |
| PANTHER | PTHR15128 | UniProtKB/TrEMBL |
| UniProt | D3ZQ85_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2008-04-30 | Stil | Scl/Tal1 interrupting locus | Stil_predicted | Scl/Tal1 interrupting locus (predicted) | 'predicted' is removed | 24709 | APPROVED |
| 2006-03-30 | Stil_predicted | Scl/Tal1 interrupting locus (predicted) | Sil_predicted | Tal1 interrupting locus (predicted) | Symbol and Name updated | 10779 | APPROVED |
| 2005-01-12 | Sil_predicted | Tal1 interrupting locus (predicted) | Symbol and Name status set to approved | 1724 | APPROVED |
| More on Stil | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1304972 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




