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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708463 Species: Rattus norvegicus RGD Object: Gene Symbol: Prf1 Name: perforin 1 (pore forming protein)

Acc ID: CHEBI:2038 Term: 5-azacytidine Definition: A N-glycosyl-1,3,5-triazine that has formula C8H12N4O5. CasRN: 320-67-2 Chemical ID: MESH:D001374

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1350272	6480464	CTD	Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein]	PMID:19394699